Abstract:
:Excitotoxic cell death stimulated by quinolinic acid injection into the striatum has a long history of "mimicking" many aspects of motor, behavioral, and neurochemical changes observed in Huntington's disease patients. In this issue of Neuron, provide insight into the role of NMDA receptors in the cell-specific excitotoxic death observed in Huntington's disease (HD) using a HD mouse model expressing full-length mutant huntingtin (htt).
journal_name
Neuronjournal_title
Neuronauthors
Ellerby LMdoi
10.1016/s0896-6273(02)00631-1subject
Has Abstractpub_date
2002-03-14 00:00:00pages
841-2issue
6eissn
0896-6273issn
1097-4199pii
S0896627302006311journal_volume
33pub_type
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