Abstract:
:A large data set of Hanwoo (Korean cattle) ESTs was analyzed to obtain differential gene expression results for the following three libraries: intramuscular fat, longissimus dorsi muscle and liver. To better understand the gene expression profiles, we identified differentially expressed genes (DEGs) via digital gene expression analysis. Hierarchical clustering of genes was performed according to their relative abundance within the six separate groups (Hanwoo fat versus non-Hanwoo fat, Hanwoo muscle versus non-Hanwoo muscle and Hanwoo liver versus non-Hanwoo liver), producing detailed patterns of gene expression. We determined the quantitative traits associated with the highly expressed genes. We also provide the first list of putative regulatory elements associated with differential tissue expression in Hanwoo cattle. In addition, we conducted evolutionary analysis that suggests a subset of genes accelerated in the bovine lineage are strongly correlated with their expression in Hanwoo muscle.
journal_name
BMB Repjournal_title
BMB reportsauthors
Lim D,Lee SH,Cho YM,Yoon D,Shin Y,Kim KW,Park HS,Kim Hdoi
10.5483/bmbrep.2010.43.2.115subject
Has Abstractpub_date
2010-02-01 00:00:00pages
115-21issue
2eissn
1976-6696issn
1976-670Xjournal_volume
43pub_type
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