Abstract：
:Two new xanthones namely cratochinone A (1) and cratochinone B (2), along with 16 known xanthones, were isolated from the roots of Cratoxylum cochinchinense. Their structures were characterized by spectroscopic methods, especially 1D and 2D NMR as well as comparison with those reported in the literature for known xanthones. All isolated compounds were evaluated for their cytotoxicity against five human cancer cell lines (KB, HeLa S-3, HT-29, MCF-7 and Hep G2 cell lines). Compounds 2, 5, and 7 showed significant cytotoxic effects against all cell lines with IC50 values in the range of 0.91-9.93 μM, while 10 exhibited cytotoxicity against the KB, HeLa S-3, and HT-29 cells with IC50 values of 7.39, 6.07, and 8.11 μM, respectively. Compound 12 exhibited cytotoxicity against both KB and HeLa S-3 cells with IC50 values of 7.28 and 9.84 μM.
journal_name
J Nat Medjournal_title
Journal of natural medicinesauthors
Natrsanga P,Jongaramruong J,Rassamee K,Siripong P,Tip-Pyang Sdoi
10.1007/s11418-019-01376-7subject
Has Abstractpub_date
2020-03-01 00:00:00pages
467-473issue
2eissn
1340-3443issn
1861-0293pii
10.1007/s11418-019-01376-7journal_volume
74pub_type
杂志文章abstract：:Two new phenanthrene and 9, 10-dihydrophenanthrene derivatives (1-2) with six known congeners (3-8) were isolated from the extraction of stems of Dendrobium officinale. Compounds 1 and 2 were based on carbon skeleton in which phenanthrene and 9, 10-dihydrophenanthrene moiety were linked with a phenylpropane unit throu...
journal_title：Journal of natural medicines
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journal_title：Journal of natural medicines
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abstract：:A new oxygenated lanostane-type triterpene, named lucidumol C, together with six known compounds, was isolated from the chloroform extract of the fruiting bodies of Ganoderma lingzhi. Structures were established based on extensive spectroscopic and chemical studies. Potential cytotoxic activities of the isolated compo...
journal_title：Journal of natural medicines
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journal_title：Journal of natural medicines
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journal_title：Journal of natural medicines
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更新日期：2011-07-01 00:00:00
abstract：:The stem of the Akebia plant, "Mokutsu", is a crude diuretic and antiphlogistic drug. Japanese products prepared from wild Akebia plants cover most of the Mokutsu market. Two Akebia plants, Akebia quinata Decaisne (Aq) and A. trifoliata Koidzumi (At) of Lardizabalaceae, are standardized as Mokutsu in Japanese pharmaco...
journal_title：Journal of natural medicines
pub_type： 信件
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更新日期：2009-07-01 00:00:00
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journal_title：Journal of natural medicines
pub_type： 杂志文章
doi：10.1007/s11418-018-1203-0
更新日期：2018-06-01 00:00:00
abstract：:From the dried rhizomes of Curcuma comosa cultivating in Thailand, 26 known sesquiterpenes were isolated: zederone, zederone epoxide, furanodienone, isofuranodienone, 1(10)Z,4Z-furanodiene-6-one, glechomanolide, dehydrocurdione, neocurdione, curdione, 7 alpha-hydroxyneocurdione, 7 beta-hydroxycurdione, germacrone-1(10...
journal_title：Journal of natural medicines
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更新日期：2009-01-01 00:00:00
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journal_title：Journal of natural medicines
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更新日期：2013-07-01 00:00:00
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journal_title：Journal of natural medicines
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更新日期：2018-01-01 00:00:00
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journal_title：Journal of natural medicines
pub_type： 杂志文章
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更新日期：2019-01-01 00:00:00
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journal_title：Journal of natural medicines
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更新日期：2020-01-01 00:00:00
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journal_title：Journal of natural medicines
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更新日期：2020-01-01 00:00:00
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journal_title：Journal of natural medicines
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doi：10.1007/s11418-017-1122-5
更新日期：2018-01-01 00:00:00
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journal_title：Journal of natural medicines
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更新日期：2016-07-01 00:00:00
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journal_title：Journal of natural medicines
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journal_title：Journal of natural medicines
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journal_title：Journal of natural medicines
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更新日期：2017-10-01 00:00:00
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journal_title：Journal of natural medicines
pub_type： 信件
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更新日期：2012-10-01 00:00:00
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journal_title：Journal of natural medicines
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更新日期：2016-01-01 00:00:00
abstract：:Pueraria candollei (P. candollei) is a traditional Thai herb widely used for estrogen replacement therapy because it contains many unique chromenes that possess potent estrogenic activity, one of which is known as isomiroestrol. Since isomiroestrol is a promising compound that is solely present in P. candollei, it can...
journal_title：Journal of natural medicines
pub_type： 杂志文章
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更新日期：2019-06-01 00:00:00
abstract：:The present study was designed to determine the protective effects of Yucca schidigera (Ys) against oxidative damage induced by acute nitrite intoxication as well as the histopathological evaluation of Ys in rats. The rats were divided into three groups each containing 12 rats: control (C); nitrite intoxication (N); Y...
journal_title：Journal of natural medicines
pub_type： 杂志文章
doi：10.1007/s11418-009-0338-4
更新日期：2009-07-01 00:00:00
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journal_title：Journal of natural medicines
pub_type： 杂志文章
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更新日期：2010-07-01 00:00:00
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journal_title：Journal of natural medicines
pub_type： 杂志文章
doi：10.1007/s11418-008-0251-2
更新日期：2008-07-01 00:00:00
abstract：:Blood-brain barrier (BBB)-permeable components in the methanolic extract of Nelumbo nucifera flowers showed accelerative effects on neurite outgrowth in PC-12 cells. Among the constituents isolated from N. nucifera flowers in our previous study, aporphine-type alkaloids, lirinidine, asimilobine, N-methylasimilobine, a...
journal_title：Journal of natural medicines
pub_type： 杂志文章
doi：10.1007/s11418-019-01368-7
更新日期：2020-01-01 00:00:00
