Development of a simple and rapid method for the detection of isomiroestrol in Pueraria candollei by an immunochromatographic strip test.

abstract：:(E)-methyl-4-hydroxy-3,5-dimethoxycinnamate, (E)-methyl-4-hydroxy-3-methoxycinnamate, (E)-methyl-4-hydroxycinnamate, (Z)-methyl-4-hydroxycinnamate, calycanthine, ursolic acid, 2-hydroxy-3-methylanthraquinone, 4-methoxybenzoic acid, 3,4,5-trimethoxybenzoic acid, methyl 4-hydroxybenzoate and allantoin were isolated from...

journal_title：Journal of natural medicines

authors： da Silva VC,de Carvalho MG,Alves AN

更新日期：2008-07-01 00:00:00

abstract：:We have previously shown that the two sesquiterpene lactones, salograviolide A (Sal A) and iso-seco-tanapartholide (TNP), isolated from the Middle Eastern indigenous plants Centaurea ainetensis and Achillea falcata, respectively, possess selective antitumor properties. Here, we aimed to assess the anticancer effects o...

journal_title：Journal of natural medicines

authors： Salla M,Fakhoury I,Saliba N,Darwiche N,Gali-Muhtasib H

更新日期：2013-07-01 00:00:00

abstract：:Four new Amaryllidaceae alkaloids (1-4) possessing a homolycorine-type or a crinine-type skeleton have been isolated from the aerial part of Zephyranthes candida, and their structures were elucidated on the basis of spectroscopic data. The stereochemistry was elucidated by combination of NOESY correlations and CD anal...

journal_title：Journal of natural medicines

authors： Shitara N,Hirasawa Y,Hasumi S,Sasaki T,Matsumoto M,Wong CP,Kaneda T,Asakawa Y,Morita H

更新日期：2014-07-01 00:00:00

abstract：:Recruitment of immune cells to adipose tissue is altered dramatically in obesity, which results in chronic inflammation of the adipose tissue that leads to metabolic disorders, such as insulin resistance and type 2 diabetes mellitus. The regulation of immune cell infiltration into adipose tissue has prophylactic and t...

journal_title：Journal of natural medicines

authors： Tsuhako R,Yoshida H,Sugita C,Kurokawa M

更新日期：2020-01-01 00:00:00

abstract：:It is generally accepted that fungi have a number of dormant gene clusters for the synthesis of secondary metabolites, and the activation of these gene clusters can expand the diversity of secondary metabolites in culture. Recent studies have revealed that the mycolic acid-containing bacterium Tsukamurella pulmonis ac...

journal_title：Journal of natural medicines

authors： Jomori T,Hara Y,Sasaoka M,Harada K,Setiawan A,Hirata K,Kimishima A,Arai M

更新日期：2020-01-01 00:00:00

abstract：:Rosae fructus is a traditional Chinese crude drug, used for purgative purposes. It is included in the Japanese Pharmacopoeia XV, in which its origin is stated to be Rosa multiflora Thunberg. These days, some imported Rosae fructus are on the market and the pharmacological activity of the imported product is in questio...

journal_title：Journal of natural medicines

authors： Kawakami S,Matsunami K,Otsuka H,Kawahata M,Yamaguchi K

更新日期：2009-01-01 00:00:00

abstract：:Chresta martii (Asteraceae) is a plant found in the Xingó region (semi-arid area) in Northeastearn Brazil, and is recognized by the local population as a traditional herb used to treat gastric diseases. This is the first report of the chemical composition, acute toxicity, and gastroprotective effect in mice of the hyd...

journal_title：Journal of natural medicines

authors： Silva AA,Bezerra MM,Chaves HV,Pereira KM,Aguiar JA,Pinto VP,Abbet C,Simões-Pires CA,Franco ES,Henriques AT,Hostettmann K,Maia MB

更新日期：2013-01-01 00:00:00

abstract：:The signaling of stem cell factor (SCF) through its receptor Kit is known to play an important role in regulating cutaneous melanogenesis. In the course of UVB-induced pigmentation, the expression of membrane-bound SCF by epidermal keratinocytes is upregulated at an early phase and subsequently activates neighboring m...

journal_title：Journal of natural medicines

authors： Kasamatsu S,Hachiya A,Shimotoyodome Y,Kameyama A,Miyauchi Y,Higuchi K,Fujimori T,Ohuchi A,Shibuya Y,Kitahara T

更新日期：2014-07-01 00:00:00

abstract：:Evodiae fructus (EF), a fruit of Evodia rutaecarpa Bentham, has long been used as an analgesic drug in traditional Chinese and Japanese medicine. However, the underlying molecular mechanism of its pharmacological action is unclear. Here, using calcium imaging, whole-cell patch-clamp recording, and behavioral analysis,...

journal_title：Journal of natural medicines

authors： Iwaoka E,Wang S,Matsuyoshi N,Kogure Y,Aoki S,Yamamoto S,Noguchi K,Dai Y

更新日期：2016-01-01 00:00:00

abstract：:Two new phenanthrene and 9, 10-dihydrophenanthrene derivatives (1-2) with six known congeners (3-8) were isolated from the extraction of stems of Dendrobium officinale. Compounds 1 and 2 were based on carbon skeleton in which phenanthrene and 9, 10-dihydrophenanthrene moiety were linked with a phenylpropane unit throu...

journal_title：Journal of natural medicines

authors： Zhao GY,Deng BW,Zhang CY,Cui YD,Bi JY,Zhang GG

更新日期：2018-01-01 00:00:00

abstract：:Oligostilbenoids are a group of natural products derived from the oxidative coupling of C6-C2-C6 units found in some plant families. A structurally diverse chemical pool is produced after the successive regioselective and stereoselective oligomerization of resveratrol. This review describes the current status and know...

journal_title：Journal of natural medicines

authors： Ito T

更新日期：2020-09-01 00:00:00

abstract：:The evaluation of the antioxidant, anti-secretory and anti-inflammatory potentials of the ethyl acetate fraction (ELC) from the root bark of Lycium chinense against ethanol-induced gastric ulcer in mice and the possible mechanisms underlying this action was performed. The results indicated that oral administration of ...

journal_title：Journal of natural medicines

authors： Chen H,Olatunji OJ,Zhou Y

更新日期：2016-07-01 00:00:00

abstract：:Shakuyakukanzoto (SKT) is a kampo medicine composed of equal proportions of Glycyrrhizae radix (G. radix) and Paeoniae radix (P. radix). A double-blind study reported that SKT significantly ameliorated painful muscle cramp in cirrhosis patients without the typical severe side effects of muscle weakness and central ner...

journal_title：Journal of natural medicines

authors： Kaifuchi N,Omiya Y,Kushida H,Fukutake M,Nishimura H,Kase Y

更新日期：2015-07-01 00:00:00

abstract：:An acyclic diterpene (plaunotol; 1) and two furanoditerpenes (plaunolide, 2 and plaunol E, 3), were isolated from Croton stellatopilosus leaves, and assessed for their inhibitory activity on nitric oxide (NO) production by lipopolysaccharide (LPS)-induced RAW264.7 cells. Plaunotol, plaunolide and plaunol E exhibited i...

journal_title：Journal of natural medicines

authors： Premprasert C,Tewtrakul S,Plubrukarn A,Wungsintaweekul J

更新日期：2013-01-01 00:00:00

abstract：:Eurycomanone, an active constituent isolated from Eurycoma longifolia Jack, was examined for modulatory effects on cytochrome P450 (CYP) isoforms CYP1A2, CYP2A6, CYP2C8, CYP2C9, CYP2C19, CYP2E1 and CYP3A4 using in vitro assays. The IC50 value was determined to assess the potencies of modulation for each CYP isoform. O...

journal_title：Journal of natural medicines

authors： Pan Y,Tiong KH,Abd-Rashid BA,Ismail Z,Ismail R,Mak JW,Ong CE

更新日期：2014-04-01 00:00:00

abstract：:Mimosa pudica is used in traditional medicine for treating various disorders such as inflammatory conditions, diarrhoea, insomnia, alopecia, urogenital infections and wounds. The present study investigated the effect of M. pudica extract (MPE) on L-arginine-induced acute necrotising pancreatitis in rats. The ethanolic...

journal_title：Journal of natural medicines

authors： Kaur J,Sidhu S,Chopra K,Khan MU

更新日期：2016-07-01 00:00:00

abstract：:Aconitum vilmorinianum Komarov is a local medicinal plant used in many well-known clinical preparations to treat rheumatism and pains in Yunnan Province, China. Phytochemical examination of the roots of A. vilmorinianum led to the isolation of three novel imine-type norditerpenoid alkaloids named vilmorrianines E-G (1...

journal_title：Journal of natural medicines

authors： Chen CL,Tan WH,Wang Y,Xue ZG,Wan CP,Yang ZY,Zhou ZH,Ma XX

更新日期：2015-10-01 00:00:00

abstract：:Blood-brain barrier (BBB)-permeable components in the methanolic extract of Nelumbo nucifera flowers showed accelerative effects on neurite outgrowth in PC-12 cells. Among the constituents isolated from N. nucifera flowers in our previous study, aporphine-type alkaloids, lirinidine, asimilobine, N-methylasimilobine, a...

journal_title：Journal of natural medicines

authors： Yano M,Nakashima S,Oda Y,Nakamura S,Matsuda H

更新日期：2020-01-01 00:00:00

abstract：:A new pyrrolidine derivative, (5S)-hydroxyethyl 2-oxopyrrolidine-5-carboxylate (1), a new flavonol glycoside, tamaraxetin 3,7-di-O-α-L-rhamnopyranoside (2), and a new triterpene saponin, polyscioside A methyl ester (3), along with six known compounds (4-9) were isolated from the leaves of Polyscias balfouriana. Their ...

journal_title：Journal of natural medicines

authors： Sugimoto S,Yamano Y,Khalil HE,Otsuka H,Kamel MS,Matsunami K

更新日期：2017-07-01 00:00:00

abstract：:Ceramicines are a series of limonoids which were isolated from the bark of Malaysian Chisocheton ceramicus (Meliaceae) and show various biological activities. Ceramicine B, in particular, has been reported to show a strong lipid droplet accumulation (LDA) inhibitory activity on a mouse pre-adipocyte cell line (MC3T3-G...

journal_title：Journal of natural medicines

authors： Nugroho AE,Hashimoto A,Wong CP,Yokoe H,Tsubuki M,Kaneda T,Hadi AHA,Morita H

更新日期：2018-01-01 00:00:00

abstract：:Acanthopanax senticosus HARMS (AS) is used as a Chinese herbal medicine and as a health supplement in Japan. However, little is known about the interaction between AS and other drugs. In this study, we investigated the effect of AS extract on intestinal drug transporter (P-glycoprotein, or P-gp) and peptide transporte...

journal_title：Journal of natural medicines

authors： Takahashi T,Kaku T,Sato T,Watanabe K,Sato J

更新日期：2010-01-01 00:00:00

abstract：:From the 1-BuOH-soluble fraction of a MeOH extract of Euphorbia hirta, collected in the Okinawa islands, three new megastigmane glucoside gallates, named hirtionosides A-C, 3-hydroxyoctanoic acid glucosides and a phenylpropanoid glucoside were isolated along with 15 known compounds. The structures of the new compounds...

journal_title：Journal of natural medicines

authors： Nomoto Y,Sugimoto S,Matsunami K,Otsuka H

更新日期：2013-04-01 00:00:00

abstract：:In this study, we analyzed the CYP3A inhibitory components of star fruit Averrhoa carambola L., using liquid chromatography-mass spectrometry (LC-MS). The stereoisomer of procyanidin B1 and B2 and/or the trimer consisting of catechin and/or epicatechin were suggested to be potent inhibitory components. ...

journal_title：Journal of natural medicines

authors： Hosoi S,Shimizu E,Arimori K,Okumura M,Hidaka M,Yamada M,Sakushima A

更新日期：2008-07-01 00:00:00

abstract：:Solvent partitioning followed by column chromatography of the MeOH extract of the seeds of Swietenia mahagoni afforded two limonoids, swietenolide (1) and 2-hydroxy-3-O-tigloylswietenolide (2). The compounds were identified by spectroscopic means. The antibacterial activity of these compounds was assessed against eigh...

journal_title：Journal of natural medicines

authors： Rahman AK,Chowdhury AK,Ali HA,Raihan SZ,Ali MS,Nahar L,Sarker SD

更新日期：2009-01-01 00:00:00

abstract：:Four hydrolyzable tannins [oenothein B (1), eugeniflorin D(2) (2), and tellimagrandins I (3) and II (4)], two related polyphenolic compounds [gallic acid (5) and quinic acid 3,5-di-O-gallate (6)], and four myricetin glycosides [myricetins 3-O-beta-D-xyloside (7), 3-O-beta-D-galactoside (8), 3-O-beta-D-galactoside 6''-...

journal_title：Journal of natural medicines

authors： Yoshimura M,Amakura Y,Tokuhara M,Yoshida T

更新日期：2008-07-01 00:00:00

abstract：:Two new xanthones namely cratochinone A (1) and cratochinone B (2), along with 16 known xanthones, were isolated from the roots of Cratoxylum cochinchinense. Their structures were characterized by spectroscopic methods, especially 1D and 2D NMR as well as comparison with those reported in the literature for known xant...

journal_title：Journal of natural medicines

authors： Natrsanga P,Jongaramruong J,Rassamee K,Siripong P,Tip-Pyang S

更新日期：2020-03-01 00:00:00

abstract：:Picrasma javanica Blume (Simaroubaceae) is a medium-sized tree that is distributed widely in tropical Asia. In our previous study, we isolated quassinoids from P. javanica bark collected in Myanmar, and reported their antiproliferative activities. In our ongoing research for the discovery of bioactive compounds from M...

journal_title：Journal of natural medicines

authors： Prema,Wong CP,Nugroho AE,Awouafack MD,Win YY,Win NN,Ngwe H,Morita H,Morita H

更新日期：2019-06-01 00:00:00

abstract：:In vitro screening methods using cultured Neuro2a cells to examine the activation (phosphorylation) of extracellular signal-regulated kinase (ERK) 1/2 and promotion of neurite outgrowth revealed that the extracts of 5 Kampo (Japanese traditional) formulations have potential as medicines for the treatment of behavioral...

journal_title：Journal of natural medicines

authors： Sawamoto A,Okuyama S,Amakura Y,Yamada R,Yoshimura M,Nakajima M,Furukawa Y

更新日期：2018-01-01 00:00:00

abstract：:The hypolipidemic activity of Symplocos cochinchinensis S. Moore leaves was studied in Triton WR-1339- and high fat diet-induced hyperlipidemic rats. In Triton WR-1339-induced hyperlipidemic rats, the hexane extract (250 and 500 mg/kg) exerted a significant (P < 0.01) lipid-lowering effect compared to ethyl acetate an...

journal_title：Journal of natural medicines

authors： Sunil C,Ignacimuthu S,Kumarappan C

更新日期：2012-01-01 00:00:00

abstract：:In our previous study, piperlonguminine from the fruit of Piper chaba was reported to promote adipogenesis in 3T3-L1 cells like the peroxisome proliferator-activated receptor-γ (PPARγ) agonist, troglitazone. In the present study, the mode of action of piperlonguminine in cells was examined. Piperlonguminine increased ...

journal_title：Journal of natural medicines

authors： Yamaguchi I,Matsuda H,Zhang H,Hamao M,Yamashita C,Kogami Y,Kon'I H,Murata M,Nakamura S,Yoshikawa M

更新日期：2014-01-01 00:00:00