Components of convolvulin from Quamoclit × multifida.

Abstract:

:Alkaline hydrolysis of the ether-insoluble resin glycoside (convolvulin) fraction of the seeds of Quamoclit × multifida (syn. Q. sloteri House, Convolvulaceae), a hybrid between Q. pennat and Q. coccinea, gave three new glycosidic acids (maltifidinic acids C, D, and E) along with three known glycosidic acids (quamoclinic acids B, C, and D) and four organic acids (2S-methylbutyric, tiglic, 2R,3R-nilic, and 7S-hydroxydecanoic acids). The structures of the new glycosidic acids were characterized on the basis of spectroscopic data as well as chemical evidence.

journal_name

J Nat Med

authors

Ono M,Kishida M,Ikegami Y,Takaki Y,Okawa M,Kinjo J,Yoshimitsu H,Nohara T,Miyahara K

doi

10.1007/s11418-010-0464-z

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

95-102

issue

1

eissn

1340-3443

issn

1861-0293

journal_volume

65

pub_type

杂志文章
  • Lucidumol C, a new cytotoxic lanostanoid triterpene from Ganoderma lingzhi against human cancer cells.

    abstract::A new oxygenated lanostane-type triterpene, named lucidumol C, together with six known compounds, was isolated from the chloroform extract of the fruiting bodies of Ganoderma lingzhi. Structures were established based on extensive spectroscopic and chemical studies. Potential cytotoxic activities of the isolated compo...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-016-0976-2

    authors: Amen YM,Zhu Q,Tran HB,Afifi MS,Halim AF,Ashour A,Mira A,Shimizu K

    更新日期:2016-07-01 00:00:00

  • Pharmacokinetics study of asperosaponin VI and its metabolites cauloside A, HN saponin F and hederagenin.

    abstract::This experiment's with aim was to study the pharmacokinetics of asperosaponin VI and its three metabolites (cauloside A, HN saponin F and hederagenin) via a sensitive high performance liquid chromatography connected with electrospray ionization triple quadrupole mass spectrum (HPLC-ESI-MS/MS). Chromatographic separati...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-014-0821-4

    authors: Liu EW,Wang JL,Han LF,Chang YX,Wang T,Huo Y,Wang L,Gao XM

    更新日期:2014-07-01 00:00:00

  • Red ginseng and 20(S)-Rg3 control testosterone-induced prostate hyperplasia by deregulating androgen receptor signaling.

    abstract::Since prostate growth is governed by the androgen signaling pathway, blockade of the pathway is regarded as an appropriate strategy for the treatment of benign prostatic hyperplasia (BPH). Panax ginseng is known to have various pharmacological activities. Of several products of its root, red ginseng, having many bioac...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-011-0609-8

    authors: Bae JS,Park HS,Park JW,Li SH,Chun YS

    更新日期:2012-07-01 00:00:00

  • Antitumor effect of the seashell protein Haishengsu on Ehrlich ascites tumor: an experimental study.

    abstract::The aim of the study was to investigate the in vivo effect of the seashell protein Haishengsu (HSS) on Ehrlich ascites tumor. Mice were inoculated with Ehrlich ascites tumor cells and randomly divided into three HSS groups and a control group. The survival times in the three HSS-treated groups was longer than in the c...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-009-0346-4

    authors: Liu JZ,Chen SG,Bin Z,Wang CB,Li GY,Wang LX

    更新日期:2009-10-01 00:00:00

  • Ferrearin C induces apoptosis via heme oxygenase-1 (HO-1) induction in neuroblastoma.

    abstract::We investigated the cytotoxicity of six neolignans (1-6), which are similar in structure to furanocyclohexenone with an angular allyl group, in human neuroblastoma cell lines (IMR-32, LA-N-1, NB-39, SK-N-SH) and normal cells [human umbilical vein endothelial cells (HUVEC) and human dermal fibroblasts (HDF)] using a 3-...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-011-0514-1

    authors: Hayama T,Tabata K,Uchiyama T,Fujimoto Y,Suzuki T

    更新日期:2011-07-01 00:00:00

  • Nondestructive prediction of oren extract powder, a herbal medicine, in suppositories by chemometric near-infrared spectroscopy.

    abstract::Near-infrared (NIR) spectroscopy combined with chemometrics has been utilized in predictions of natural medicine content without destroying samples. Suppositories (oren powdered extract content 0, 0.5, 1.0, 2.5, 10, 12.5, and 15%) were produced by mixing oren powdered extract with macrogol mixture consisting of 1 part...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-011-0596-9

    authors: Teraoka R,Abe H,Sugama T,Ito K,Aburada M,Otsuka M

    更新日期:2012-04-01 00:00:00

  • Bioactive constituents obtained from the fruits of Citrus aurantium.

    abstract::Three new compounds, citrusauranosides A (1), B (2), and C (3), along with 22 known compounds (4-25) were obtained from the 70% ethanol-water extract of the fruits of Citrus aurantium L.. Their structures were identified by spectroscopic methods. Among the known compounds, 14, 15, 17 and 23 were firstly obtained from ...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-018-1255-1

    authors: Zhang Y,Huang P,He W,Sakah KJ,Ruan J,Li Z,Wang T

    更新日期:2019-01-01 00:00:00

  • Correction to: Comparison of glycyrrhizin content in 25 major kinds of Kampo extracts containing Glycyrrhizae Radix used clinically in Japan.

    abstract::The article Comparison of glycyrrhizin content in 25 major kinds of Kampo extracts containing Glycyrrhizae Radix used clinically in Japan, written by Mitsuhiko Nose, Momoka Tada, Rika Kojima, Kumiko Nagata, Shinsuke Hisaka, Sayaka Masada, Masato Homma and Takashi Hakamatsuka, was originally published Online First with...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章,已发布勘误

    doi:10.1007/s11418-018-1195-9

    authors: Nose M,Tada M,Kojima R,Nagata K,Hisaka S,Masada S,Homma M,Hakamatsuka T

    更新日期:2018-03-01 00:00:00

  • Magnolol inhibits myotube atrophy induced by cancer cachexia through myostatin signaling pathway in vitro.

    abstract::Cancer cachexia is a complex and multifactorial syndrome that influences about 50-80% of cancer patients and may lead to 20% of cancer deaths and muscle atrophy is the key characteristic of the syndrome. Recent researches have shown that myostatin is a negative regulator in the growth and differentiation of skeletal m...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-020-01428-3

    authors: Ge Z,Liu D,Shang Y,Li Y,Chen SZ

    更新日期:2020-09-01 00:00:00

  • Chemical structures of constituents from the leaves of Polyscias balfouriana.

    abstract::A new pyrrolidine derivative, (5S)-hydroxyethyl 2-oxopyrrolidine-5-carboxylate (1), a new flavonol glycoside, tamaraxetin 3,7-di-O-α-L-rhamnopyranoside (2), and a new triterpene saponin, polyscioside A methyl ester (3), along with six known compounds (4-9) were isolated from the leaves of Polyscias balfouriana. Their ...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-017-1081-x

    authors: Sugimoto S,Yamano Y,Khalil HE,Otsuka H,Kamel MS,Matsunami K

    更新日期:2017-07-01 00:00:00

  • Protective effects of aloperine on neonatal rat primary cultured hippocampal neurons injured by oxygen-glucose deprivation and reperfusion.

    abstract::Aloperine (ALO), one of the alkaloids isolated from Sophora alopecuroides L., is traditionally used for various diseases including neuronal disorders. This study investigated the protective effects of ALO on neonatal rat primary-cultured hippocampal neurons injured by oxygen-glucose deprivation and reperfusion (OGD/RP...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-015-0928-2

    authors: Ma NT,Zhou R,Chang RY,Hao YJ,Ma L,Jin SJ,Du J,Zheng J,Zhao CJ,Niu Y,Sun T,Li W,Koike K,Yu JQ,Li YX

    更新日期:2015-10-01 00:00:00

  • Effects of shakuyakukanzoto and its absorbed components on twitch contractions induced by physiological Ca2+ release in rat skeletal muscle.

    abstract::Shakuyakukanzoto (SKT) is a kampo medicine composed of equal proportions of Glycyrrhizae radix (G. radix) and Paeoniae radix (P. radix). A double-blind study reported that SKT significantly ameliorated painful muscle cramp in cirrhosis patients without the typical severe side effects of muscle weakness and central ner...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-015-0890-z

    authors: Kaifuchi N,Omiya Y,Kushida H,Fukutake M,Nishimura H,Kase Y

    更新日期:2015-07-01 00:00:00

  • Determination of (E)-ferulic acid content in the root of Angelica acutiloba: a simple chemical evaluation method for crude drug quality control.

    abstract::The root of Angelica acutiloba Kitagawa is an important crude drug in Kampo medicines (traditional Japanese medicine). Chemical evaluation of crude drugs is crucial to ensuring the safety and efficacy of herbal medicine; however, there is currently no chemical standard for the A. acutiloba crude drug in Japanese pharm...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-018-1190-1

    authors: Shinjyo N,Fuchino H,Kawahara N,Hishida A

    更新日期:2018-06-01 00:00:00

  • Production of monoclonal antibodies against antitumor cyclohexapeptide RA-VII from Rubia cordifolia and their characterization.

    abstract::An immunoassay system was established for the estimation of the quantity of an antitumor cyclic hexapeptide RA-VII (1) from Rubia cordifolia L. and R. akane Nakai (Rubiaceae). First, 1 was converted into its hapten, which was then conjugated with a carrier protein to be used as an effective antigen to obtain its monoc...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-011-0508-z

    authors: Hasuda T,Hitotsuyanagi Y,Takeya K

    更新日期:2011-07-01 00:00:00

  • A molecular pharmacology study into the anti-inflammatory actions of Euphorbia hirta L. on the LPS-induced RAW 264.7 cells through selective iNOS protein inhibition.

    abstract::Euphorbia hirta L. has been widely used in India and Chinese society. The molecular pharmacology basis of its anti-inflammatory effect is revealed in this work. The ethanol extract of Euphorbia hirta L. (Eh) and its active component were studied in lipopolysaccharide (LPS)-activated macrophage cells (RAW 264.7) as an ...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-010-0417-6

    authors: Shih MF,Cheng YD,Shen CR,Cherng JY

    更新日期:2010-07-01 00:00:00

  • Acacienone, a terpenoid-like natural product having an unprecedented C20 framework isolated from Acacia mangium leaves.

    abstract::A novel C20 natural product, acacienone (1), was isolated from the leaves of Acacia mangium collected in Bangladesh. The structure of compound 1 was elucidated by spectral studies and X-ray crystallographic analysis. Acacienone (1) possesses a terpenoid-related tetracyclic framework containing 20 carbons with biogenet...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-020-01457-y

    authors: Hara Y,Totsugi Y,Ichikawa H,Harada S,Fujii K,Ahmed F,Sadhu SK,Arai MA,Ishibashi M

    更新日期:2021-01-01 00:00:00

  • Sedative effects of vapor inhalation of agarwood oil and spikenard extract and identification of their active components.

    abstract::Agarwood oil and spikenard extract were examined for their sedative activity using a spontaneous vapor administration system. It was shown that inhalation of agarwood oil vapor sedated mice. The main volatile constituents of the oil were found to be benzylacetone [agarwood oil from a Hong Kong market (1)], or alpha-gu...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-007-0177-0

    authors: Takemoto H,Ito M,Shiraki T,Yagura T,Honda G

    更新日期:2008-01-01 00:00:00

  • Constituents of the lichen Peltigera dolichorrhiza.

    abstract::A new aromatic derivative, 5-(3,4-dihydroxyphenyl)-3-methylcyclohex-2-enone (1), and three known compounds, peltigerine, solorinine, and phenyl butanoid, were isolated from the MeOH extract of the lichen Peltigera dolichorrhiza (Peltigeraceae). Their structures were determined by 1D and 2D nuclear magnetic resonance a...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-010-0409-6

    authors: Yoshikawa K,Kunioka E,Kokudo N,Hashimoto T

    更新日期:2010-07-01 00:00:00

  • Methylquercetins stimulate melanin biosynthesis in a three-dimensional skin model.

    abstract::In a previous study, we found that both synthetic 3-O-methylquercetin (3MQ) and 3,4',7-O-trimethylquercetin (34'7TMQ) increased extracellular melanin content. 34'7TMQ increased the activity of melanogenic enzymes by stimulating the p38 pathway and the expression of microphthalmia-associated transcription factor (MITF)...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-018-1175-0

    authors: Yamauchi K,Mitsunaga T

    更新日期:2018-03-01 00:00:00

  • A glycerol α-D-glucuronide and a megastigmane glycoside from the leaves of Guettarda speciosa L.

    abstract::From the 1-BuOH-soluble fraction of a MeOH extract of the leaves of Guettarda speciosa L., two new compounds (1, 2) were isolated together with six known compounds. Spectroscopic analysis of 1 and 2 established their structures to be derivatives of a glycerol α-glucuronide and a megastigmane glycoside, respectively. H...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-010-0484-8

    authors: Cai WH,Matsunami K,Otsuka H,Shinzato T,Takeda Y

    更新日期:2011-04-01 00:00:00

  • Rosmarinic acid in Argusia argentea inhibits snake venom-induced hemorrhage.

    abstract::A methanolic extract of Argusia (or Messerschmidia or Tournefortia) argentea (Boraginaceae) significantly inhibited hemorrhage induced by crude venom of Trimeresurus flavoviridis. The extract was then separated according to antivenom activity by using silica gel column chromatography and HPLC equipped with an octadecy...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-010-0428-3

    authors: Aung HT,Nikai T,Niwa M,Takaya Y

    更新日期:2010-10-01 00:00:00

  • Antiplasmodial indole alkaloids from Leuconotis griffithii.

    abstract::A new indole alkaloid, leucoridine A N-oxide (1), consisting of two units of a strychnan type of skeleton, was isolated from the leaves of Leuconotis griffithii. Its structure was elucidated by various spectroscopic means such as NMR and MS, and also by chemical means. Antiplasmodial activity against Plasmodium falcip...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-011-0574-2

    authors: Nugroho AE,Hirasawa Y,Piow WC,Kaneda T,Hadi AH,Shirota O,Ekasari W,Widyawaruyanti A,Morita H

    更新日期:2012-04-01 00:00:00

  • Rigenolides D-H, norsecoiridoid and secoiridoids from Gentiana rigescens Franch.

    abstract::Five new compounds, rigenolides D-H (1-5), were isolated from the aerial parts of Gentiana rigescens Franch. Their structures were assigned by detailed spectroscopic analyses and chemical conversions. Rigenolides D (1) and E (2) were elucidated to be a secoiridoid and a norsecoiridoid, respectively, possessing a dieno...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-018-1181-2

    authors: Suyama Y,Tanaka N,Kawazoe K,Murakami K,Li SL,Sun HD,Kashiwada Y

    更新日期:2018-03-01 00:00:00

  • Isoorientin exerts a urate-lowering effect through inhibition of xanthine oxidase and regulation of the TLR4-NLRP3 inflammasome signaling pathway.

    abstract::Isoorientin (ISO), a natural flavonoid compound, has been identified in several plants and its biological activity is determined and the study on lowering uric acid has not been reported. In view of the current status of treatment of hyperuricemia, we evaluated the hypouricemic effects of ISO in vivo and in vitro, and...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-020-01464-z

    authors: An MF,Wang MY,Shen C,Sun ZR,Zhao YL,Wang XJ,Sheng J

    更新日期:2021-01-01 00:00:00

  • Development of a simple and rapid method for the detection of isomiroestrol in Pueraria candollei by an immunochromatographic strip test.

    abstract::Pueraria candollei (P. candollei) is a traditional Thai herb widely used for estrogen replacement therapy because it contains many unique chromenes that possess potent estrogenic activity, one of which is known as isomiroestrol. Since isomiroestrol is a promising compound that is solely present in P. candollei, it can...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-019-01307-6

    authors: Chaingam J,Kitisripanya T,Krittanai S,Sakamoto S,Tanaka H,Putalun W

    更新日期:2019-06-01 00:00:00

  • Antithrombosis activity of protocatechuic and shikimic acids from functional plant Pinus densiflora Sieb. et Zucc needles.

    abstract::Pine needle extract (PE) and fermented pine needle extract (FPE) have been reported to show various biological and pharmacological activities such as antioxidant, anti-inflammatory, anti-bacterial, anti-cholesterol, gastrointestinal motility control, and fibrinolytic effect. The aims of our research were to isolate fi...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-015-0956-y

    authors: Park J,Lee B,Choi H,Kim W,Kim HJ,Cheong H

    更新日期:2016-07-01 00:00:00

  • Antibacterial activity of two limonoids from Swietenia mahagoni against multiple-drug-resistant (MDR) bacterial strains.

    abstract::Solvent partitioning followed by column chromatography of the MeOH extract of the seeds of Swietenia mahagoni afforded two limonoids, swietenolide (1) and 2-hydroxy-3-O-tigloylswietenolide (2). The compounds were identified by spectroscopic means. The antibacterial activity of these compounds was assessed against eigh...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-008-0287-3

    authors: Rahman AK,Chowdhury AK,Ali HA,Raihan SZ,Ali MS,Nahar L,Sarker SD

    更新日期:2009-01-01 00:00:00

  • Different expression systems resulted in varied binding properties of anti-paclitaxel single-chain variable fragment antibody clone 1C2.

    abstract::The binding properties of recombinant antibody fragments, such as affinity and specificity, determine their usefulness for therapeutic and analytical applications. Anti-paclitaxel single-chain variable fragment clone 1C2 (anti-PT scFv1C2) was expressed using Escherichia coli cell and Bombyx mori larvae expression syst...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-017-1136-z

    authors: Yusakul G,Sakamoto S,Nuntawong P,Tanaka H,Morimoto S

    更新日期:2018-01-01 00:00:00

  • Aqueous-methanolic extract of sweet flag (Acorus calamus) possesses cardiac depressant and endothelial-derived hyperpolarizing factor-mediated coronary vasodilator effects.

    abstract::This investigation was aimed to probe the pharmacological base of medicinal use of Acorus calamus in ischemic heart diseases. Effect on heart parameters was studied in isolated rabbit heart while coronary vasodilator effect was studied in isolated bovine coronary arterial rings, suspended in tissue baths filled with K...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-011-0561-7

    authors: Shah AJ,Gilani AH

    更新日期:2012-01-01 00:00:00

  • Satureja khuzestanica attenuates apoptosis in hyperglycemic PC12 cells and spinal cord of diabetic rats.

    abstract::Several studies have indicated the involvement of oxidative stress and high glucose-induced cell death in the development of diabetic neuropathy. Satureja khuzestanica has been recommended in the literature as a remedy for the treatment of diabetes, and also contains antioxidant agents. Here, we investigated the possi...

    journal_title:Journal of natural medicines

    pub_type: 杂志文章

    doi:10.1007/s11418-012-0646-y

    authors: Kaeidi A,Esmaeili-Mahani S,Abbasnejad M,Sheibani V,Rasoulian B,Hajializadeh Z,Pasban-Aliabadi H

    更新日期:2013-01-01 00:00:00