Abstract:
:A new aromatic derivative, 5-(3,4-dihydroxyphenyl)-3-methylcyclohex-2-enone (1), and three known compounds, peltigerine, solorinine, and phenyl butanoid, were isolated from the MeOH extract of the lichen Peltigera dolichorrhiza (Peltigeraceae). Their structures were determined by 1D and 2D nuclear magnetic resonance and mass spectroscopy analysis.
journal_name
J Nat Medjournal_title
Journal of natural medicinesauthors
Yoshikawa K,Kunioka E,Kokudo N,Hashimoto Tdoi
10.1007/s11418-010-0409-6subject
Has Abstractpub_date
2010-07-01 00:00:00pages
362-4issue
3eissn
1340-3443issn
1861-0293journal_volume
64pub_type
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journal_title:Journal of natural medicines
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abstract::We investigated the cytotoxicity of six neolignans (1-6), which are similar in structure to furanocyclohexenone with an angular allyl group, in human neuroblastoma cell lines (IMR-32, LA-N-1, NB-39, SK-N-SH) and normal cells [human umbilical vein endothelial cells (HUVEC) and human dermal fibroblasts (HDF)] using a 3-...
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journal_title:Journal of natural medicines
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journal_title:Journal of natural medicines
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abstract::The hypolipidemic activity of Symplocos cochinchinensis S. Moore leaves was studied in Triton WR-1339- and high fat diet-induced hyperlipidemic rats. In Triton WR-1339-induced hyperlipidemic rats, the hexane extract (250 and 500 mg/kg) exerted a significant (P < 0.01) lipid-lowering effect compared to ethyl acetate an...
journal_title:Journal of natural medicines
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abstract::The hydroalcoholic extract of fruits of Ziziphus jujuba (ZJ) was investigated for its anti-inflammatory effect using acute and chronic models of inflammation in rat. Wistar albino rats of either sex were employed in the present study (n = 6). Acute inflammation was induced by subplantar administration of carrageenan (...
journal_title:Journal of natural medicines
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更新日期:2011-07-01 00:00:00
abstract::A new pyrrolidine derivative, (5S)-hydroxyethyl 2-oxopyrrolidine-5-carboxylate (1), a new flavonol glycoside, tamaraxetin 3,7-di-O-α-L-rhamnopyranoside (2), and a new triterpene saponin, polyscioside A methyl ester (3), along with six known compounds (4-9) were isolated from the leaves of Polyscias balfouriana. Their ...
journal_title:Journal of natural medicines
pub_type: 杂志文章
doi:10.1007/s11418-017-1081-x
更新日期:2017-07-01 00:00:00
abstract::Antihypertensive treatment is highly important to prevent the progression of chronic kidney disease. Shichimotsukokato (SKT), a traditional Japanese medicine (i.e., Kampo formula), lowered systolic blood pressure (SBP) in experimental animal models of hypertension. However, its mechanism of action has not been fully e...
journal_title:Journal of natural medicines
pub_type: 杂志文章
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更新日期:2016-04-01 00:00:00
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journal_title:Journal of natural medicines
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journal_title:Journal of natural medicines
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abstract::Chemotherapy-induced peripheral neuropathy (CIPN) manifests as mechanical allodynia and hyperalgesia, and is one of the main adverse effects of chemotherapeutic agents. Currently available therapeutic drugs are not sufficiently effective for the management of this adverse effect in the clinic. Therefore, the developme...
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journal_title:Journal of natural medicines
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abstract::The article Comparison of glycyrrhizin content in 25 major kinds of Kampo extracts containing Glycyrrhizae Radix used clinically in Japan, written by Mitsuhiko Nose, Momoka Tada, Rika Kojima, Kumiko Nagata, Shinsuke Hisaka, Sayaka Masada, Masato Homma and Takashi Hakamatsuka, was originally published Online First with...
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pub_type: 杂志文章,已发布勘误
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更新日期:2018-03-01 00:00:00
abstract::Ceramicines are a series of limonoids which were isolated from the bark of Malaysian Chisocheton ceramicus (Meliaceae) and show various biological activities. Ceramicine B, in particular, has been reported to show a strong lipid droplet accumulation (LDA) inhibitory activity on a mouse pre-adipocyte cell line (MC3T3-G...
journal_title:Journal of natural medicines
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abstract::Solvent partitioning followed by column chromatography of the MeOH extract of the seeds of Swietenia mahagoni afforded two limonoids, swietenolide (1) and 2-hydroxy-3-O-tigloylswietenolide (2). The compounds were identified by spectroscopic means. The antibacterial activity of these compounds was assessed against eigh...
journal_title:Journal of natural medicines
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更新日期:2009-01-01 00:00:00
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journal_title:Journal of natural medicines
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journal_title:Journal of natural medicines
pub_type: 杂志文章
doi:10.1007/s11418-010-0464-z
更新日期:2011-01-01 00:00:00
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journal_title:Journal of natural medicines
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journal_title:Journal of natural medicines
pub_type: 杂志文章
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更新日期:2020-03-01 00:00:00
abstract::Visceral obesity induces insulin resistance and is recognized as an important risk factor for metabolic syndrome (MS). Therefore, inhibition of lipid absorption from the intestine is regarded as an effective way of preventing MS. Terminalia bellirica is extensively used in Ayurvedic medicine in India and neighboring c...
journal_title:Journal of natural medicines
pub_type: 杂志文章
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更新日期:2012-07-01 00:00:00
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journal_title:Journal of natural medicines
pub_type: 杂志文章
doi:10.1007/s11418-016-1015-z
更新日期:2016-10-01 00:00:00
abstract::Rosae fructus is a traditional Chinese crude drug, used for purgative purposes. It is included in the Japanese Pharmacopoeia XV, in which its origin is stated to be Rosa multiflora Thunberg. These days, some imported Rosae fructus are on the market and the pharmacological activity of the imported product is in questio...
journal_title:Journal of natural medicines
pub_type: 杂志文章
doi:10.1007/s11418-008-0293-5
更新日期:2009-01-01 00:00:00
abstract::Four new Amaryllidaceae alkaloids (1-4) possessing a homolycorine-type or a crinine-type skeleton have been isolated from the aerial part of Zephyranthes candida, and their structures were elucidated on the basis of spectroscopic data. The stereochemistry was elucidated by combination of NOESY correlations and CD anal...
journal_title:Journal of natural medicines
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更新日期:2014-07-01 00:00:00