Therapeutic effect of exendin-4, a long-acting analogue of glucagon-like peptide-1 receptor agonist, on nerve regeneration after the crush nerve injury.

abstract：:A novel methylamine-selective amperometric bienzyme biosensor based on recombinant primary amine oxidase isolated from the recombinant yeast strain Saccharomyces cerevisiae and commercial horseradish peroxidase is described. Two amine oxidase preparations were used: free enzyme (AMO) and covalently immobilized on the ...

journal_title：BioMed research international

authors： Stasyuk NY,Smutok OV,Zakalskiy AE,Zakalska OM,Gonchar MV

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Varicocele is associated with high levels of DNA damage in spermatozoa due to oxidative stress and elevated levels of sperm DNA fragmentation, which has been currently proposed to be an essential additional diagnostic test to be recommended for patients with clinical varicocele. The aim of this study was to ...

journal_title：BioMed research international

authors： Kadioglu TC,Aliyev E,Celtik M

更新日期：2014-01-01 00:00:00

abstract：:Regulation of hematopoietic stem cell release, migration, and homing from the bone marrow (BM) and of the mobilization pathway involves a complex interaction among adhesion molecules, cytokines, proteolytic enzymes, stromal cells, and hematopoietic cells. The identification of new mechanisms that regulate the traffick...

journal_title：BioMed research international

authors： Alvarez P,Carrillo E,Vélez C,Hita-Contreras F,Martínez-Amat A,Rodríguez-Serrano F,Boulaiz H,Ortiz R,Melguizo C,Prados J,Aránega A

更新日期：2013-01-01 00:00:00

abstract：:Somatostatin (SST) receptors (SSTRs) belong to the typical 7-transmembrane domain family of G-protein-coupled receptors. Five distinct subtypes (termed SSTR1-5) have been identified, with SSTR2 showing the highest affinity for natural SST and synthetic SST analogs. Most neuroendocrine tumors (NETs) have high expressio...

journal_title：BioMed research international

authors： Xu C,Zhang H

更新日期：2015-01-01 00:00:00

abstract：:The body's autoimmune process is involved in the development of Graves' disease (GD), which is manifested by an overactive thyroid gland. In some patients, autoreactive inflammatory reactions contribute to the development of symptoms such as thyroid ophthalmopathy, and the subsequent signs and symptoms are derived fro...

journal_title：BioMed research international

authors： Łacheta D,Miśkiewicz P,Głuszko A,Nowicka G,Struga M,Kantor I,Poślednik KB,Mirza S,Szczepański MJ

更新日期：2019-11-12 00:00:00

abstract：:Chronic kidney disease (CKD) is considered a public health problem, assuming epidemic proportions worldwide. In this context, the preponderance of CKD prevalence in male over age-matched female patients is of note. In the present study, we investigated the impact of the gender on the development of experimental CKD in...

journal_title：BioMed research international

authors： Fanelli C,Dellê H,Cavaglieri RC,Dominguez WV,Noronha IL

更新日期：2017-01-01 00:00:00

abstract：:Pregnancy is associated with various physiological changes which may lead to significant alterations in the pharmacokinetics of many drugs. The present study was aimed to investigate the potential effects of pregnancy on the pharmacokinetic profile of zonisamide (ZNM) in the rabbit. Seven female rabbits were used in t...

journal_title：BioMed research international

authors： Matar KM

更新日期：2013-01-01 00:00:00

abstract：:Targeted drug delivery using folate receptors is one of the most interesting chemotherapeutic research areas over the past few years. A novel folate targeted copolymer was synthesized using dextran stearate coupled to folic acid. FT-IR and NMR spectroscopy were used to confirm successful conjugation. Micelles prepared...

journal_title：BioMed research international

authors： Varshosaz J,Hassanzadeh F,Sadeghi-Aliabadi H,Firozian F

更新日期：2014-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2017/7268308.]. ...

journal_title：BioMed research international

authors： Lin JA,Blanco R,Shibata Y,Nakamoto T,Lin KH

更新日期：2018-07-05 00:00:00

abstract：Objectives:To evaluate the role of short-term low-dose glucocorticoids in mild COVID-19 patients. Methods:We conducted a retrospective, cross-sectional, single-center study in Kunming, China. A total of 33 mild COVID-19 cases were divided into two treatment groups (with and without glucocorticoids, methylprednisolone,...

journal_title：BioMed research international

authors： Fu HY,Luo Y,Gao JP,Wang L,Li HJ,Li X,Xue L,Tang XQ,Li HW,Du YR

更新日期：2020-09-23 00:00:00

abstract：:The objective of the present investigation was to study the effect of combination of telmisartan with cisplatin in oral cancer cachexia induced by applying 0.5% 4-nitroquinoline-1-oxide (4-NQO) in propylene glycol to tongue, thrice a week for 8 weeks. From 8th to 22nd week, cisplatin (0.23 mg/kg, i.v.) was administere...

journal_title：BioMed research international

authors： Patel BM,Damle D

更新日期：2013-01-01 00:00:00

abstract：:Plantar fasciitis is a cause of chronic pain under the heel and bottom of the foot. One of the treatments to reduce pain consists of using plantar orthoses to address specific imbalances during foot placement or gait. The aim of the present study was to determine if reduction of pain with a treatment based on plantar ...

journal_title：BioMed research international

authors： Moyne-Bressand S,Dhieux C,Dousset E,Decherchi P

更新日期：2018-12-12 00:00:00

abstract：Objective:To investigate the prevalence of infections due to carbapenem-resistant Klebsiella pneumoniae (CRKP) among ICU admission patients in central China and develop a reliable prediction model. Methods:Five hundred and seven consecutive ICU admission patients with Klebsiella pneumoniae (KP) infection were enrolled...

journal_title：BioMed research international

authors： Li Y,Shen H,Zhu C,Yu Y

更新日期：2019-03-27 00:00:00

abstract：:Cancer is a significant global health concern affecting men and women worldwide. Although current chemopreventive drugs could inhibit the growth of cancer cells, they exert many adverse side effects. Dietary factor plays a crucial role in the management of cancers and has drawn the attention of researchers to be used ...

journal_title：BioMed research international

authors： Tan BL,Norhaizan ME

更新日期：2017-01-01 00:00:00

abstract：:Increasing consumption of tobacco and alcohol has led to a steady increase in the incidence of head and neck cancers in Asia. The drawbacks associated with the existing chemotherapeutic and surgical interventions have necessitated the development of a safer alternative for therapy of head and neck cancers. In this stu...

journal_title：BioMed research international

authors： Mohan A,Narayanan S,Sethuraman S,Krishnan UM

更新日期：2014-01-01 00:00:00

abstract：:[This corrects the article DOI: 10.1155/2016/3746232.]. ...

journal_title：BioMed research international

authors： Liu Q,Wang C,Li P,Liu J,Huang G,Song S

更新日期：2016-01-01 00:00:00

abstract：Aim:This study aims to evaluate the accuracy of scanned images of 4 clinically used intraoral scanners (CS3600, i500, Trios3, Omnicam) when scanning the surface of full arch models with various kinds of orthodontic brackets in the presence of artificial saliva. Materials and Methods. Four study models were prepared; bo...

journal_title：BioMed research international

authors： Song J,Kim M

更新日期：2020-02-27 00:00:00

abstract：:Objective. To evaluate the gut mucosa and blood-brain barrier (BBB) pharmacokinetic permeability properties of the plant N-alkylamide pellitorine. Methods. Pure pellitorine and an Anacyclus pyrethrum extract were used to investigate the permeation of pellitorine through (1) a Caco-2 cell monolayer, (2) the rat gut aft...

journal_title：BioMed research international

authors： Veryser L,Bracke N,Wynendaele E,Joshi T,Tatke P,Taevernier L,De Spiegeleer B

更新日期：2016-01-01 00:00:00

abstract：:Aim. In periodontology lasers have been suggested for the photodynamic therapy (PDT): such therapy can be defined as the inactivation of cells, microorganisms, or molecules induced by light and not by heat. The aim of this study was to evaluate results of PDT using a 980 nm diode laser (Wiser Doctor Smile, Lambda SPA,...

journal_title：BioMed research international

authors： Caccianiga G,Baldoni M,Ghisalberti CA,Paiusco A

更新日期：2016-01-01 00:00:00

abstract：:Although multimodal therapies including surgery, chemotherapy, and radiotherapy have improved clinical outcomes of patients with bone and soft tissue sarcomas, the prognosis of patients has plateaued over these 20 years. Immunotherapies have shown the effectiveness for several types of advanced tumors. Immunotherapies...

journal_title：BioMed research international

authors： Uehara T,Fujiwara T,Takeda K,Kunisada T,Ozaki T,Udono H

更新日期：2015-01-01 00:00:00

abstract：:Liver regeneration after partial hepatectomy (PH) is a highly orchestrated biological process in which synchronized hepatocyte proliferation is induced after massive liver mass loss. Hepatocyte proliferation could be regulated by multiple signals, such as miRNAs and autophagy, but underlying mechanism remains unclear....

journal_title：BioMed research international

authors： Lu T,Hao J,Shen C,Gu G,Zhang J,Xu N

更新日期：2018-07-31 00:00:00

abstract：:It is well known that Down syndrome (DS) is a condition in which extra genetic material causes delays in the way a child develops, both mentally and physically. Intellectual disability is the foremost and most debilitating trait, which caused loss of cognitive abilities and the development of early onset Alzheimer's d...

journal_title：BioMed research international

authors： Yu B,Zhang B,Zhou WB,Wang QW,Yuan P,Yang YQ,Kong J

更新日期：2015-01-01 00:00:00

abstract：:Preeclampsia (PE) is a unique complication of pregnancy, the pathogenesis of which has been generally accepted to be associated with the dysfunctions of extravillous trophoblast (EVT) including proliferation, apoptosis, and migration and invasion. Decorin (DCN) has been proved to be a decidua-derived TGF-binding prote...

journal_title：BioMed research international

authors： Zou Y,Yu X,Lu J,Jiang Z,Zuo Q,Fan M,Huang S,Sun L

更新日期：2015-01-01 00:00:00

abstract：:Chronic Obstructive Pulmonary Disease (COPD) is defined as a disease characterized by persistent, progressive airflow limitation. Recent studies have underlined that COPD is correlated to many systemic manifestations, probably due to an underlying pattern of systemic inflammation. In COPD fractional exhaled Nitric Oxi...

journal_title：BioMed research international

authors： Malerba M,Radaeli A,Olivini A,Damiani G,Ragnoli B,Montuschi P,Ricciardolo FL

更新日期：2014-01-01 00:00:00

abstract：:New antimicrobial properties of products derived from Humulus lupulus L. such as antiadherent and antibiofilm activities were evaluated. The growth of gram-positive but not gram-negative bacteria was inhibited to different extents by these compounds. An extract of hop cones containing 51% xanthohumol was slightly less...

journal_title：BioMed research international

authors： Rozalski M,Micota B,Sadowska B,Stochmal A,Jedrejek D,Wieckowska-Szakiel M,Rozalska B

更新日期：2013-01-01 00:00:00

abstract：:Several studies suggested that migraine attack onset shows a circadian variation; however, there has not been an overview and synthesis of these findings. A PubMed search with keywords "migraine" AND "circadian" resulted in ten studies directly investigating this topic. Results of these studies mostly show that migrai...

journal_title：BioMed research international

authors： Baksa D,Gecse K,Kumar S,Toth Z,Gal Z,Gonda X,Juhasz G

更新日期：2019-08-25 00:00:00

abstract：:The number of RNA-Seq studies has grown in recent years. The design of RNA-Seq studies varies from very simple (e.g., two-condition case-control) to very complicated (e.g., time series involving multiple samples at each time point with separate drug treatments). Most of these publically available RNA-Seq studies are d...

journal_title：BioMed research international

authors： Kumar P,Halama A,Hayat S,Billing AM,Gupta M,Yousri NA,Smith GM,Suhre K

更新日期：2015-01-01 00:00:00

abstract：:This study was conducted to evaluate the effect of mesenchymal stem cells (MSCs) and a novel curcumin derivative (NCD) on HepG2 cells (hepatoma cell line) and to investigate their effect on Notch1 signaling pathway target genes. HepG2 cells were divided into HepG2 control group, HepG2 cells treated with MSC conditione...

journal_title：BioMed research international

authors： Abdel Aziz MT,Khaled HM,El Hindawi A,Roshdy NK,Rashed LA,Sabry D,Hassouna AA,Taha F,Ali WI

更新日期：2013-01-01 00:00:00

abstract：:Vitamin B-6 has a strong antioxidative effect. It would be useful to determine whether vitamin B-6 supplementation had effects on antioxidant capacities in patients with hepatocellular carcinoma (HCC) who had recently undergone tumor resection. Thirty-three HCC patients were randomly assigned to either the placebo (n ...

journal_title：BioMed research international

authors： Cheng SB,Lin PT,Liu HT,Peng YS,Huang SC,Huang YC

更新日期：2016-01-01 00:00:00

abstract：:To compare the clinical efficacy and radiological outcome of treating 4-level cervical spondylotic myelopathy (CSM) with either anterior cervical discectomy and fusion (ACDF) or "skip" corpectomy and fusion, 48 patients with 4-level CSM who had undergone ACDF or SCF at our hospital were analyzed retrospectively betwee...

journal_title：BioMed research international

authors： Li F,Li Z,Huang X,Chen Z,Zhang F,Shen H,Kang Y,Zhang Y,Cai B,Hou T

更新日期：2015-01-01 00:00:00