Gender Differences in the Progression of Experimental Chronic Kidney Disease Induced by Chronic Nitric Oxide Inhibition.

abstract：:Background. Prior studies have demonstrated that conventional and emerging CV risk factors are associated with worsening arterial stiffness among end-stage renal disease (ESRD) patients on hemodialysis. The present cross-sectional study evaluates the association between the etiology of ESRD and arterial stiffness amon...

journal_title：BioMed research international

authors： El Ghoul B,Daaboul Y,Korjian S,El Alam A,Mansour A,Hariri E,Samad S,Salameh P,Dahdah G,Blacher J,Safar ME,Aoun Bahous S

更新日期：2017-01-01 00:00:00

abstract：:Although multimodal therapies including surgery, chemotherapy, and radiotherapy have improved clinical outcomes of patients with bone and soft tissue sarcomas, the prognosis of patients has plateaued over these 20 years. Immunotherapies have shown the effectiveness for several types of advanced tumors. Immunotherapies...

journal_title：BioMed research international

authors： Uehara T,Fujiwara T,Takeda K,Kunisada T,Ozaki T,Udono H

更新日期：2015-01-01 00:00:00

abstract：:A 35 KDa protein referred to as F3 was purified from the seeds of Borreria hispida by precipitation with 80% ammonium sulphate and gel filtration on Sephadex G-100 column. RP-HPLC analysis of protein fraction (F3) on an analytical C-18 column produced a single peak, detected at 220 nm. F3 showed an apparent molecular ...

journal_title：BioMed research international

authors： Rupachandra S,Sarada DV

更新日期：2014-01-01 00:00:00

abstract：:The total knee arthroplasty (TKA) is the gold standard for patients with an advanced symptomatic gonarthrosis. However, there are very few publications dealing with the primary TKA for patients with a proximal tibia fracture. In our retrospective study we evaluated 30 patients treated with a TKA for a proximal tibia f...

journal_title：BioMed research international

authors： Haufe T,Förch S,Müller P,Plath J,Mayr E

更新日期：2016-01-01 00:00:00

abstract：:Retinoblastoma protein (pRB) interacts with E2F and other protein factors to play a pivotal role in regulating the expression of target genes that induce cell cycle arrest, apoptosis, and differentiation. pRB controls the local promoter activity and has the ability to change the structure of nucleosomes and/or chromos...

journal_title：BioMed research international

authors： Uchida C

更新日期：2016-01-01 00:00:00

abstract：:Cancer cells acquire unique secretome compositions that contribute to tumor development and metastasis. The aim of our study was to elucidate the biological processes involved in cervical cancer, by performing a proteomic analysis of the secretome from the following informative cervical cell lines: SiHa (HPV16+), HeLa...

journal_title：BioMed research international

authors： Kontostathi G,Zoidakis J,Makridakis M,Lygirou V,Mermelekas G,Papadopoulos T,Vougas K,Vlamis-Gardikas A,Drakakis P,Loutradis D,Vlahou A,Anagnou NP,Pappa KI

更新日期：2017-01-01 00:00:00

abstract：:Breast cancer mortality disparities continue, particularly for uninsured and minority women. A number of effective evidence-based interventions (EBIs) exist for addressing barriers to mammography screening; however, their uptake and use in community has been limited. Few cancer-specific studies have evaluated adapted ...

journal_title：BioMed research international

authors： Highfield L,Hartman MA,Bartholomew LK,Balihe P,Ausborn VA

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To quantitatively measure changes in cerebral perfusion in select regions of interest in the brain during urinary urgency in women with overactive bladder (OAB) using arterial spin labeling (ASL). METHODS:Twelve women with OAB and 10 controls underwent bladder filling and rated urinary urgency (scale 0-10). AS...

journal_title：BioMed research international

authors： Arya NG,Weissbart SJ,Xu S,Bhavsar R,Rao H

更新日期：2017-01-01 00:00:00

abstract：:The expression profile of long noncoding RNA (lncRNA) in human epicardial adipose tissue (EAT) has not been widely studied. In the present study, we performed RNA sequencing to analyze the expression profiles of lncRNA and mRNA in EAT in coronary artery disease (CAD) patients with and without heart failure (HF). Our r...

journal_title：BioMed research international

authors： Zheng M,Zhao L,Yang X

更新日期：2019-07-04 00:00:00

abstract：INTRODUCTION:Human mesenchymal stromal cells (hMSCs) exhibit the potential to accelerate bone healing by enhanced osteogenic differentiation. Interleukin-1β is highly expressed during fracture healing and has been demonstrated to exert a significant impact on the differentiation behaviour of hMSCs. Here, we investigate...

journal_title：BioMed research international

authors： Voss JO,Loebel C,Bara JJ,Fussinger MA,Duttenhoefer F,Alini M,Stoddart MJ

更新日期：2015-01-01 00:00:00

abstract：:Lipases are water-soluble enzymes that act on insoluble substrates and catalyze the hydrolysis of long-chain triglycerides. Lipases play a vital role in the food, detergent, chemical, and pharmaceutical industries. In the past, fungal lipases gained significant attention in the industries due to their substrate specif...

journal_title：BioMed research international

authors： Gopinath SC,Anbu P,Lakshmipriya T,Hilda A

更新日期：2013-01-01 00:00:00

abstract：:Introduction. NOTCH pathway and TP53 protein are involved in the development of fibrosis and autoimmune disorders, respectively. The aim of this study was to evaluate the role of single nucleotide polymorphisms (SNPs) of NOTCH3 and TP53 genes and serum anti-TP53 antibodies with the susceptibility, clinical subset of s...

journal_title：BioMed research international

authors： Zmorzyński S,Wojcierowska-Litwin M,Kowal M,Michalska-Jakubus M,Styk W,Filip AA,Walecka I,Krasowska D

更新日期：2020-02-25 00:00:00

abstract：:Objectives. To construct a frailty index from next-of-kin information of the last year of life of community-dwelling 50 years old or older adults and test its association with health services utilization. Methods. Cross-sectional analysis from next-of-kin data available from the last wave of the Mexican Health and Agi...

journal_title：BioMed research international

authors： Pérez-Zepeda MU,Cesari M,Carrillo-Vega MF,Salinas-Escudero G,Tella-Vega P,García-Peña C

更新日期：2017-01-01 00:00:00

abstract：:This study evaluated the microtensile bond strength (μTBS) of 1-step self-etch adhesives (1-SEAs) and 2-step self-etch adhesives (2-SEAs) to pulp chamber dentin immediately after bleaching with 2 types of common bleaching techniques. Pulp chamber dentin of bovine teeth was bleached using 30% hydrogen peroxide (H2O2) s...

journal_title：BioMed research international

authors： Haruyama A,Kameyama A,Kato J,Takemoto S,Oda Y,Kawada E,Takahashi T,Furusawa M

更新日期：2016-01-01 00:00:00

abstract：:Mild cognitive impairment (MCI) refers to a transitional state between normal aging and dementia and is a syndrome with cognitive decline greater than expected for an individual's age and educational level. As a subtype of MCI, amnestic mild cognitive impairment (aMCI) most often leads to Alzheimer's disease. This stu...

journal_title：BioMed research international

authors： Zhao Z,Lu J,Jia X,Chao W,Han Y,Jia J,Li K

更新日期：2014-01-01 00:00:00

abstract：:Bone defects are repaired using either natural or synthetic bone grafts. Poly(ϵ-caprolactone) (PCL), β-tricalcium phosphate (TCP), and poly(lactic-co-glycolic acid) (PLGA) are widely used as synthetic materials for tissue engineering. This study aimed to investigate the bone-healing capacity of PCL/PLGA/duck beak scaf...

journal_title：BioMed research international

authors： Lee JY,Son SJ,Son JS,Kang SS,Choi SH

更新日期：2016-01-01 00:00:00

abstract：:Purpose. The aim of the present study was to elucidate the metabolic mechanisms associated with chronic fatigue syndrome (CFS) via an analysis of urine metabolites prior to and following exercise in a rat model. Methods. A rat model of CFS was established using restraint-stress, forced exercise, and crowded and noisy ...

journal_title：BioMed research international

authors： Shao C,Ren Y,Wang Z,Kang C,Jiang H,Chi A

更新日期：2017-01-01 00:00:00

abstract：:Molecular recognition elements (MREs) can be short sequences of single-stranded DNA, RNA, small peptides, or antibody fragments. They can bind to user-defined targets with high affinity and specificity. There has been an increasing interest in the identification and application of nucleic acid molecular recognition el...

journal_title：BioMed research international

authors： Hong KL,Sooter LJ

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:To evaluate tumor structure in children with diffuse intrinsic pontine glioma (DIPG) using histogram analyses of mean diffusivity (MD), determine potential treatment and corticosteroid-related effects on MD, and monitor changes in MD distributions over time. MATERIALS AND METHODS:DTI was performed on a 1.5T GE...

journal_title：BioMed research international

authors： Steffen-Smith EA,Sarlls JE,Pierpaoli C,Shih JH,Bent RS,Walker L,Warren KE

更新日期：2014-01-01 00:00:00

abstract：:The hepatoprotective and antioxidant activity of Bauhinia hookeri ethanol extract (BHE) against CCl4-induced liver injury was investigated in mice. BHE was administered (500 and 1000 mg/kg/day) along with CCl4 for 6 weeks. The hepatic marker enzymes: alanine aminotransferase (ALT), aspartate aminotransferase (AST), an...

journal_title：BioMed research international

authors： Al-Sayed E,Martiskainen O,Seif el-Din SH,Sabra AN,Hammam OA,El-Lakkany NM,Abdel-Daim MM

更新日期：2014-01-01 00:00:00

abstract：:Bacteria are a source of a large number of secondary metabolites with several biomedical and biotechnological applications. In recent years, there has been tremendous progress in the development of novel synthetic biology approaches both to increase the production rate of secondary metabolites of interest in native pr...

journal_title：BioMed research international

authors： de Frias UA,Pereira GKB,Guazzaroni ME,Silva-Rocha R

更新日期：2018-07-09 00:00:00

abstract：OBJECTIVE:This study aims to explore the usage of intraocular pressure measurements as the early indicator of the increase in intra-abdominal pressure. METHODS:In this prospective study, 40 patients undergoing elective surgery were included. Patients were divided into four groups of 10 patients. The control group (Gro...

journal_title：BioMed research international

authors： Ece I,Vatansev C,Kucukkartallar T,Tekin A,Kartal A,Okka M

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:Radiopharmaceutical production process must adhere to current good manufacturing process (CGMP) compliance to ensure the quality of precursor, prodrug (active pharmaceutical ingredient, API), and the final drug product that meet acceptance criteria. We aimed to develop an automated system for production of CG...

journal_title：BioMed research international

authors： Chi YT,Chu PC,Chao HY,Shieh WC,Chen CC

更新日期：2014-01-01 00:00:00

abstract：:Bones are the most frequent site for breast cancer cells to settle and spread (metastasise); bone metastasis is considered to have a substantial impact on the quality of patients with common cancers. However, majority of breast cancers develop insensitivity to conventional chemotherapy which provides only palliation a...

journal_title：BioMed research international

authors： Kamba AS,Ismail M,Ibrahim TA,Zakaria ZA,Gusau LH

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The aim of this study is to investigate the effectiveness of preemptive thoracic epidural analgesia (TEA) comparing conventional postoperative epidural analgesia on thoracotomy. MATERIAL AND METHODS:Forty-four patients were randomized in to two groups (preemptive: Group P, control: Group C). Epidural cathet...

journal_title：BioMed research international

authors： Erturk E,Aydogdu Kaya F,Kutanis D,Besir A,Akdogan A,Geze S,Tugcugil E

更新日期：2014-01-01 00:00:00

abstract：PURPOSE:Assessing the role of breast MRI compared to galactography in patients with unilateral bloody or serous-bloody nipple discharge. MATERIALS AND METHODS:Retrospective study including 53 unilateral discharge patients who performed galactography and MRI. We evaluated the capability of both techniques in identifyin...

journal_title：BioMed research international

authors： Manganaro L,D'Ambrosio I,Gigli S,Di Pastena F,Giraldi G,Tardioli S,Framarino M,Porfiri LM,Ballesio L

更新日期：2015-01-01 00:00:00

abstract：Purpose:In this study, we examined whether the associations between working hours, job satisfaction, and work-life balance are mediated by occupational stress. In addition, we tested whether perceived time control helps moderate the effects of working hours and occupational stress. Methodology:Questionnaires were admi...

journal_title：BioMed research international

authors： Hsu YY,Bai CH,Yang CM,Huang YC,Lin TT,Lin CH

更新日期：2019-06-23 00:00:00

abstract：:Experimental animal models improve our understanding of technical problems in peritoneal dialysis PD, and such studies contribute to solving crucial clinical problems. We established an acute and chronic PD model in nonuremic and uremic rats. We observed that kinetics of PD in rats change as the animals are aging, and...

journal_title：BioMed research international

authors： Pawlaczyk K,Baum E,Schwermer K,Hoppe K,Lindholm B,Breborowicz A

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:The aim of this study is to describe the robotic assisted transfer device (RATD) and an initial focus group evaluation by end users. The purpose of the device is to aid in the transfers of people with disabilities to and from their electric powered wheelchair (EPW) onto other surfaces. The device can be used fo...

journal_title：BioMed research international

authors： Grindle GG,Wang H,Jeannis H,Teodorski E,Cooper RA

更新日期：2015-01-01 00:00:00

abstract：:This study introduced a combined computational fluid dynamics (CFD) and echocardiography methodology to simulate blood flow in the single right ventricle (SRV) and normal ventricles to study the intraventricular flow. Derived from echocardiographic image loops, CFD-based three-dimensional (3D) flow models of normal su...

journal_title：BioMed research international

authors： Chen LJ,Tong ZR,Wang Q,Zhang YQ,Liu JL

更新日期：2018-01-16 00:00:00