In vitro ultrastructural changes of MCF-7 for metastasise bone cancer and induction of apoptosis via mitochondrial cytochrome C released by CaCO3/Dox nanocrystals.

abstract：:Vitamin B-6 has a strong antioxidative effect. It would be useful to determine whether vitamin B-6 supplementation had effects on antioxidant capacities in patients with hepatocellular carcinoma (HCC) who had recently undergone tumor resection. Thirty-three HCC patients were randomly assigned to either the placebo (n ...

journal_title：BioMed research international

authors： Cheng SB,Lin PT,Liu HT,Peng YS,Huang SC,Huang YC

更新日期：2016-01-01 00:00:00

abstract：:Tripartite Motif Containing 11 (TRIM11), an E3 ubiquitin ligase, is identified as a carcinogen causing certain human cancers. However, the specific role of TRIM11 is still uncovered in human osteosarcoma (OS) cells. To explore the role of TRIM11 in OS cells, TRIM11 was induced by silencing and overexpression in OS cel...

journal_title：BioMed research international

authors： Wang Z,Xu X,Tang W,Zhu Y,Hu J,Zhang X

更新日期：2019-12-25 00:00:00

abstract：:This study aimed to evaluate the genes that were expressed in the healing bones around SLA-treated titanium orthodontic mini-implants in a beagle at early (1-week) and late (4-week) stages with RNA-sequencing (RNA-Seq). Samples from sites of surgical defects were used as controls. Total RNA was extracted from the tiss...

journal_title：BioMed research international

authors： Nahm KY,Heo JS,Lee JH,Lee DY,Chung KR,Ahn HW,Kim SH

更新日期：2015-01-01 00:00:00

abstract：:Cognitive dysfunction is an important complicated disease in obesity. Exercise ameliorates obesity and the related cognitive dysfunction. However, the underlying mechanism is still unclear. In this study, we investigated whether aerobic interval training (AIT) could attenuate high-fat-diet- (HFD-) associated cognitive...

journal_title：BioMed research international

authors： Shi Z,Li C,Yin Y,Yang Z,Xue H,Mu N,Wang Y,Liu M,Ma H

更新日期：2018-03-22 00:00:00

abstract：:It is unclear whether the methyltransferase-like 14 (METTL14) protein promotes or suppresses cancer growth. We examined the association between METTL14 expression, cancer progression, and patient prognosis in a total of 398 breast cancer tissue specimens. Significantly fewer cancer tissue specimens compared with norma...

journal_title：BioMed research international

authors： Dong XF,Wang Y,Huang BF,Hu GN,Shao JK,Wang Q,Tang CH,Wang CQ

更新日期：2020-10-20 00:00:00

abstract：:Waldenström macroglobulinemia (WM) is a malignant lymphoplasma-proliferative disorder with IgM monoclonal gammopathy. A recent whole-genome study identified MYD88 L265P as the key mutation in WM. We investigated MYD88 mutations in conjunction with cytogenetic study in 22 consecutive Korean WM patients. Conventional G-...

journal_title：BioMed research international

authors： Kim JA,Im K,Park SN,Kwon J,Choi Q,Hwang SM,Sekiguchi N,Yoon SS,Lee DS,Kim SY

更新日期：2014-01-01 00:00:00

abstract：Objective:The aim of this study is to compare the clinical outcomes of two-level percutaneous endoscopic lumbar discectomy (PELD) and foraminoplasty PELD in treating highly migrated lumbar disc herniations. Methods:Patients with highly migrated lumbar disc herniations were enrolled from May 2014 to June 2016. Low back...

journal_title：BioMed research international

authors： Wu X,Fan G,He S,Gu X,Yang Y

更新日期：2019-10-13 00:00:00

abstract：INTRODUCTION:The aim of this report is to study the graft and patient survival in a large cohort of recipients with an analysis of factors that may affect the final outcomes. METHODS:Between March 1976 and March 2008, 1967 consecutive live-donor renal transplants were carried out. Various variables that may have an im...

journal_title：BioMed research international

authors： Ghoneim MA,Bakr MA,Refaie AF,Akl AI,Shokeir AA,Shehab El-Dein AB,Ammar HM,Ismail AM,Sheashaa HA,El-Baz MA

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Physical activity is associated with reduced mortality and morbidity. Cardiac rehabilitation (CR) is an effective intervention for patients with cardiovascular disease (CVD). Unfortunately, women are less likely to engage in, or sustain, regular physical activity. Objectives were to (1) describe women's guid...

journal_title：BioMed research international

authors： Arthur HM,Blanchard C,Gunn E,Kodis J,Walker S,Toner B

更新日期：2013-01-01 00:00:00

abstract：:Heart failure (HF) can be defined as cardiac structural or functional abnormality leading to a series of symptoms due to deficiency of oxygen delivery. In the clinical practice, acute heart failure (AHF) is usually performed as cardiogenic shock (CS), pulmonary edema, and single or double ventricle congestive heart fa...

journal_title：BioMed research international

authors： Zhong ZP,Wang H,Hou XT

更新日期：2016-01-01 00:00:00

abstract：:Background. Aortic valve calcification (AVC) is a common feature of aging and is related to coronary artery disease. Although abdominal visceral adipose tissue (VAT) plays fundamental roles in coronary artery disease, the relationship between abdominal VAT and AVC is not fully understood. Methods. We investigated 259 ...

journal_title：BioMed research international

authors： Oikawa M,Owada T,Yamauchi H,Misaka T,Machii H,Yamaki T,Sugimoto K,Kunii H,Nakazato K,Suzuki H,Saitoh S,Takeishi Y

更新日期：2016-01-01 00:00:00

abstract：:A 35 KDa protein referred to as F3 was purified from the seeds of Borreria hispida by precipitation with 80% ammonium sulphate and gel filtration on Sephadex G-100 column. RP-HPLC analysis of protein fraction (F3) on an analytical C-18 column produced a single peak, detected at 220 nm. F3 showed an apparent molecular ...

journal_title：BioMed research international

authors： Rupachandra S,Sarada DV

更新日期：2014-01-01 00:00:00

abstract：:Subarachnoid hemorrhage (SAH) is a devastating neurological disorder. Patients with aneurysmal SAH develop secondary complications that are important causes of morbidity and mortality. Aside from secondary neurological injuries, SAH has been associated with nonneurologic medical complications, such as neurocardiogenic...

journal_title：BioMed research international

authors： Chen S,Li Q,Wu H,Krafft PR,Wang Z,Zhang JH

更新日期：2014-01-01 00:00:00

abstract：:Coronary heart disease (CHD) has become one of the leading causes of death and functional impairment in the world. Hyperglycemia is associated with an increased risk of cardiovascular disease. It was speculated that miRNAs in peripheral blood were a primary parameter in discriminating CHD. The biological characteristi...

journal_title：BioMed research international

authors： Jiang Y,Liu N,Xue B,Hou J,Lin C,Ren J,Liu J

更新日期：2017-01-01 00:00:00

abstract：:Polyketide belongs to a family of abundant natural products typically produced by the filamentous soil bacteria Streptomyces. Similar to the biosynthesis of most secondary metabolites produced in the Streptomyces species, polyketide compounds are synthesized through tight regulatory networks in the cell, and thus extr...

journal_title：BioMed research international

authors： Nah JH,Kim HJ,Lee HN,Lee MJ,Choi SS,Kim ES

更新日期：2013-01-01 00:00:00

abstract：Background:Liver ischaemia-reperfusion injury (IRI) remains a problem in liver transplantation. Interleukin-4 (IL-4) has been found to reduce liver IRI, but the exact mechanism remains unclear. Methods:Donor livers were infused with recombinant IL-4 or normal saline during cold storage, and the hepatocellular apoptosi...

journal_title：BioMed research international

authors： Deng M,Wang J,Wu H,Wang M,Cao D,Li J,Wu Y,Gong J

更新日期：2020-03-18 00:00:00

abstract：:In response to cytokine signalling and other factors, CD4-positive T lymphocytes differentiate into distinct populations that are characterized by the production of certain cytokines and are controlled by different master transcription factors. The spectrum of such populations, which was initially limited to Th1 and T...

journal_title：BioMed research international

authors： Ivanova EA,Orekhov AN

更新日期：2015-01-01 00:00:00

abstract：:One of the most important tasks of a living organism is to maintain its genetic integrity with respect to stress. Endoplasmic reticulum (ER) has a crucial role in sensing cellular homeostasis by controlling metabolism, proteostasis, and several signaling processes. ER stressors can induce autophagy-dependent survival;...

journal_title：BioMed research international

authors： Holczer M,Márton M,Kurucz A,Bánhegyi G,Kapuy O

更新日期：2015-01-01 00:00:00

abstract：:CD13 is a membrane glycoprotein with aminopeptidase activity, expressed on several cell types, including myeloid cells (dendritic cells, monocytes, macrophages, neutrophils, etc.). CD13 participates in several functions such as proteolytic regulation of bioactive peptides, viral receptor, angiogenesis, and tumor metas...

journal_title：BioMed research international

authors： Garay-Canales CA,Licona-Limón I,Ortega E

更新日期：2018-03-29 00:00:00

abstract：:Spinal cord stimulation has been utilized for decades in the treatment of numerous conditions such as failed back surgery and phantom limb syndromes, arachnoiditis, cancer pain, and others. The placement of the stimulating electrode array was originally subdural but, to minimize surgical complexity and reduce the risk...

journal_title：BioMed research international

authors： Gibson-Corley KN,Flouty O,Oya H,Gillies GT,Howard MA

更新日期：2014-01-01 00:00:00

abstract：:Bacterial infections are the most common cause of purulent soft tissue inflammations in the head and neck area. These bacteria are also responsible for the majority of inflammatory complications after third molar removal. The key to success of antibacterial treatment in both cases is the use of an appropriate antibact...

journal_title：BioMed research international

authors： Bogacz M,Morawiec T,Śmieszek-Wilczewska J,Janowska-Bogacz K,Bubiłek-Bogacz A,Rój R,Pinocy K,Mertas A

更新日期：2019-10-07 00:00:00

abstract：Background:It is unclear whether computer navigation can improve the accuracy and reliability of targeted lower limb alignment correction following open-wedge high tibial osteotomy (HTO). This meta-analysis was designed to compare the accuracy and reliability of limb alignment correction between computer navigated and ...

journal_title：BioMed research international

authors： Han SB,Kim HJ,Lee DH

更新日期：2017-01-01 00:00:00

abstract：:Introduction. NOTCH pathway and TP53 protein are involved in the development of fibrosis and autoimmune disorders, respectively. The aim of this study was to evaluate the role of single nucleotide polymorphisms (SNPs) of NOTCH3 and TP53 genes and serum anti-TP53 antibodies with the susceptibility, clinical subset of s...

journal_title：BioMed research international

authors： Zmorzyński S,Wojcierowska-Litwin M,Kowal M,Michalska-Jakubus M,Styk W,Filip AA,Walecka I,Krasowska D

更新日期：2020-02-25 00:00:00

abstract：AIM:Gastrointestinal mucositis is a frequent complication of antineoplastic chemotherapy, but the effects of chemotherapy on mucosal defense mechanisms remain poorly understood. We studied the effects of cisplatin on mucin, one of the principal defense factors of the gastrointestinal mucosa, and evaluated the efficacy ...

journal_title：BioMed research international

authors： Yamamoto H,Ishihara K,Takeda Y,Koizumi W,Ichikawa T

更新日期：2013-01-01 00:00:00

abstract：:Diarrhea is a major clinical problem affecting foals up to 3 months of age. The aim of this study was to identify enteric microorganisms involved in monoinfections and coinfections and the associated virulence factors in healthy and diarrheic foals. Diarrheic (D) (n = 56) and nondiarrheic (ND) foals (n = 60) up to thr...

journal_title：BioMed research international

authors： Olivo G,Lucas TM,Borges AS,Silva RO,Lobato FC,Siqueira AK,da Silva Leite D,Brandão PE,Gregori F,de Oliveira-Filho JP,Takai S,Ribeiro MG

更新日期：2016-01-01 00:00:00

abstract：:A point mutation of mitochondrial DNA (mtDNA) at nucleotide position 3243 A to G (mt.3243A>G) is involved in many common diseases, including maternally inherited diabetes and deafness (MIDD) and mitochondrial encephalomyopathy, lactic acidosis with stroke-like episodes (MELAS). However, the mutant level of mt.3243A>G ...

journal_title：BioMed research international

authors： Rong E,Wang H,Hao S,Fu Y,Ma Y,Wang T

更新日期：2018-11-13 00:00:00

abstract：:Effective alteration of the recalcitrance properties like crystallization of cellulose, lignin shield, and interlinking of lignocellulosic biomass is an ideal way to utilize the full-scale potential for biofuel production. This study exhibited three different pretreatment effects to enhance the digestibility of corn s...

journal_title：BioMed research international

authors： Siddhu MA,Li J,Zhang J,Huang Y,Wang W,Chen C,Liu G

更新日期：2016-01-01 00:00:00

abstract：:Initiation and maintenance of atrial fibrillation (AF) is often associated with pharmacologically or pathologically induced bradycardic states. Even drugs specifically developed in order to counteract cardiac arrhythmias often combine their action with bradycardia and, in turn, with development of AF, via still largel...

journal_title：BioMed research international

authors： Cacciani F,Zaniboni M

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Histones play important roles in both host defenses and inflammation related to microbial infection. A peptide mimotope (SSV) was identified from a novel histone H1 monoclonal antibody (16G9 mAb) that was shown to inhibit the mixed lymphocyte reaction. In the present study, an anti-SSV producing hybridoma wa...

journal_title：BioMed research international

authors： Kusano T,Chiang KC,Inomata M,Shimada Y,Ohmori N,Goto T,Sato S,Goto S,Nakano T,Kawamoto S,Takaoka Y,Shiraishi N,Noguchi T,Kitano S

更新日期：2015-01-01 00:00:00

abstract：:Due to alarming increase in population and rapid industrialization, drinking water quality is being deteriorated day by day in Pakistan. This review sums up the outcomes of various research studies conducted for drinking water quality status of different areas of Pakistan by taking into account the physicochemical pro...

journal_title：BioMed research international

authors： Daud MK,Nafees M,Ali S,Rizwan M,Bajwa RA,Shakoor MB,Arshad MU,Chatha SAS,Deeba F,Murad W,Malook I,Zhu SJ

更新日期：2017-01-01 00:00:00