Abstract:
:Heart failure (HF) can be defined as cardiac structural or functional abnormality leading to a series of symptoms due to deficiency of oxygen delivery. In the clinical practice, acute heart failure (AHF) is usually performed as cardiogenic shock (CS), pulmonary edema, and single or double ventricle congestive heart failure. CS refers to depressed or insufficient cardiac output (CO) attributable to myocardial infarction, fulminant myocarditis, acute circulatory failure attributable to intractable arrhythmias or the exacerbation of chronic heart failure, postcardiotomy low CO syndrome, and so forth. Epidemiological studies have shown that CS has higher in-hospital mortality in patients with AHF. Besides, we call the induced, sustained circulatory failure even after administration of high doses of inotropes and vasopressors refractory cardiogenic shock. In handling these cases, mechanical circulatory support devices are usually needed. In this review, we discuss the current application status and clinical points in utilizing extracorporeal membrane oxygenation (ECMO).
journal_name
Biomed Res Intjournal_title
BioMed research internationalauthors
Zhong ZP,Wang H,Hou XTdoi
10.1155/2016/7263187subject
Has Abstractpub_date
2016-01-01 00:00:00pages
7263187eissn
2314-6133issn
2314-6141journal_volume
2016pub_type
杂志文章,评审abstract::Tuberculosis is an infectious disease caused by Mycobacterium tuberculosis (Mtb, i.e., the aetiological agent); the WHO has established this disease as high priority due to its ensuing mortality. Mtb uses a range of mechanisms for preventing its elimination by an infected host; new, viable alternatives for blocking th...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/8680935
更新日期:2019-04-14 00:00:00
abstract::A novel methylamine-selective amperometric bienzyme biosensor based on recombinant primary amine oxidase isolated from the recombinant yeast strain Saccharomyces cerevisiae and commercial horseradish peroxidase is described. Two amine oxidase preparations were used: free enzyme (AMO) and covalently immobilized on the ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/480498
更新日期:2014-01-01 00:00:00
abstract:Background:DNA methylation is essential for regulating gene expression, and the changes of DNA methylation status are commonly discovered in disease. Therefore, identification of differentially methylation patterns, especially differentially methylated regions (DMRs), in two different groups is important for understand...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/1070645
更新日期:2018-11-18 00:00:00
abstract::The relationship between oxidative stress and miRNA changes in placenta as a potential mechanism involved in preeclampsia (PE) is not fully elucidated. We investigated the impact of oxidative stress on miRNAs and mRNA expression profiles of genes associated with PE in villous 3A first trimester trophoblast cells expos...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/257090
更新日期:2015-01-01 00:00:00
abstract::Macrophages, especially their activation state, are closely related to the progression of diabetic nephropathy. Classically activated macrophages (M1) are proinflammatory effectors, while alternatively activated macrophages (M2) exhibit anti-inflammatory properties. 1,25-Dihydroxyvitamin D3 has renoprotective roles th...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/157834
更新日期:2015-01-01 00:00:00
abstract::A surface plasmon resonance- (SPR-) based recognition method applying H-2 Ld:Ig/peptides complexes for ex vivo monitoring cellular immune responses during murine infection with Leishmania (Leishmania) amazonensis is described. Lymphocytes from lesion-draining popliteal lymph nodes were captured on a carboxylated senso...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2017/9089748
更新日期:2017-01-01 00:00:00
abstract::Autoimmunity remains a complex physiologic deviation, enabled and perpetuated by a variety of interplayers and pathways. Simplistic approaches, targeting either isolated end-effectors of more centrally placed interactors of these mechanisms, are continuously tried in an effort to comprehend and halt cascades with pote...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2014/973609
更新日期:2014-01-01 00:00:00
abstract::Poly(ADP-ribose) polymerase (PARP) inhibitors have proven to be successful agents in inducing synthetic lethality in several malignancies. Several PARP inhibitors have reached clinical trial testing for treatment in different cancers, and, recently, Olaparib (AZD2281) has gained both United States Food and Drug Admini...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2016/2346585
更新日期:2016-01-01 00:00:00
abstract::Several lines of evidence indicate that amyloid β (Aβ), particularly Aβ oligomers (AβOs), plays a causative role in Alzheimer's disease. However, the mechanisms underlying the action of an anti-AβO antibody to clarify the toxic action of AβOs remain elusive. Here, we showed that the anti-AβO antibody (monoclonal 72D9)...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/984041
更新日期:2013-01-01 00:00:00
abstract:Background:Yes-associated protein 1 (YAP1) is an effector of Hippo pathway, which plays a significant role in cell proliferation and tumor progression. The relationship between YAP1 and gastrointestinal cancer has been explored in many previous studies. We conducted a meta-analysis to explore the prognostic effect of Y...
journal_title:BioMed research international
pub_type: 杂志文章,meta分析
doi:10.1155/2018/4039173
更新日期:2018-11-14 00:00:00
abstract::Both human adipose tissue-derived mesenchymal stem cells (ASCs) and umbilical cord-derived mesenchymal stem cells (UC-MSCs) have been explored as attractive mesenchymal stem cells (MSCs) sources, but very few parallel comparative studies of these two cell types have been made. We designed a side-by-side comparative st...
journal_title:BioMed research international
pub_type: 杂志文章,收录出版
doi:10.1155/2013/438243
更新日期:2013-01-01 00:00:00
abstract::The small nucleolar RNA host gene 12 (SNHG12) has been reported to play an important role in the tumorigenesis and progression of PCa, but the functional underlying mechanism has not been studied clearly. We detected the expression level of SNHG12 in PCa tissues and matched adjacent normal tissues that were collected ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/8812923
更新日期:2020-12-22 00:00:00
abstract::Primary ciliary dyskinesia (PCD) is a clinical rare peculiar disorder, mainly featured by respiratory infection, tympanitis, nasosinusitis, and male infertility. Previous study demonstrated it is an autosomal recessive disease and by 2017 almost 40 pathologic genes have been identified. Among them are the leucine-rich...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/1854269
更新日期:2018-01-08 00:00:00
abstract::[This retracts the article DOI: 10.1155/2014/479180.]. ...
journal_title:BioMed research international
pub_type: 撤回出版物
doi:10.1155/2016/4938464
更新日期:2016-01-01 00:00:00
abstract::The framework of graph theory provides useful tools for investigating the neural substrates of neuropsychiatric disorders. Graph description measures may be useful as predictor variables in classification procedures. Here, we consider several centrality measures as predictor features in a classification algorithm to i...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/380531
更新日期:2014-01-01 00:00:00
abstract::Glioblastoma (GBM) is a primary neuroepithelial tumor of the central nervous system, characterized by an extremely aggressive clinical phenotype. Patients with GBM have a poor prognosis and only 3-5% of them survive for more than 5 years. The current GBM treatment standards include maximal resection followed by radiot...
journal_title:BioMed research international
pub_type: 杂志文章,评审
doi:10.1155/2017/8013575
更新日期:2017-01-01 00:00:00
abstract:Background:This study is aimed at identifying unknown clinically relevant genes involved in colorectal cancer using bioinformatics analysis. Methods:Original microarray datasets GSE107499 (ulcerative colitis), GSE8671 (colorectal adenoma), and GSE32323 (colorectal cancer) were downloaded from the Gene Expression Omnib...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/1204605
更新日期:2020-05-23 00:00:00
abstract::Candida krusei is osmotolerant yeast used for the production of glycerol. Addition of osmolyte such as NaCl into culture medium can increase the production of glycerol from glucose, but osmolytes may burden the glycerol separation. A coencapsulation method was suggested to create local extracellular hyperosmotic stres...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/467263
更新日期:2013-01-01 00:00:00
abstract:Aim:Little is known about the association between cancer antigen 125 (MUC16/CA125) concentrations and tumor diameter of patients with hepatocellular carcinoma (HCC) and low AFP levels. To fill this gap in our knowledge, we conducted a retrospective study of 427 patients with HCC with AFP ≤200 ng/mL who underwent R0 res...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2019/6959637
更新日期:2019-09-29 00:00:00
abstract::Plant-associated bacteria provide important services to host plants. Environmental factors such as cultivar type and pedoclimatic conditions contribute to shape their diversity. However, whether these environmental factors may influence the plant growth promoting (PGP) potential of the root-associated bacteria is not ...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2013/491091
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVES:To study effects of a one-year multicomponent intervention on perceived environmental barriers in hip fracture patients. DESIGN:Randomized controlled trial of a 12-month home-based rehabilitation aiming to improve mobility and function (ISRCTN53680197); secondary analyses. Subjects. Community-dwelling hip f...
journal_title:BioMed research international
pub_type: 杂志文章,随机对照试验
doi:10.1155/2013/769645
更新日期:2013-01-01 00:00:00
abstract:Methods:In the study, we included 86 children diagnosed with atopic asthma (n = 25), allergic rhinitis (n = 20), and atopic dermatitis (n = 20) and healthy control subjects (n = 21) of Caucasian origin from the Polish population. The blood leukocyte expression of 31 genes involved in neuroinflammatory response (neurotr...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/7196981
更新日期:2020-06-10 00:00:00
abstract::Acute kidney injury (AKI) is associated with an increased risk of developing advanced chronic kidney disease (CKD). Yet, effective interventions to prevent this conversion are unavailable for clinical practice. In this study, we examined the beneficial effects of Tanshinone IIA on renal fibrosis in a mouse model of fo...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2015/867140
更新日期:2015-01-01 00:00:00
abstract:Objective:To evaluate the performance of contrast-enhanced mammography (CEM) compared to magnetic resonance imaging (MRI) for estimating residual tumor size after neoadjuvant chemotherapy (NAC) in women with newly diagnosed breast cancer. Methods:The institutional review board approved this study. This prospective stu...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/8531916
更新日期:2018-11-08 00:00:00
abstract::Feed efficiency (FE) is an important trait affecting costs in swine industry. Investigation on FE-related genes in different tissues is valuable for molecular breeding. Hypothalamus is a convergent and integrated centre for multiple nutrient-related signals. The present study identified 363 differentially expressed (D...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2018/5862571
更新日期:2018-12-26 00:00:00
abstract::Background. The epidemiology of atopic dermatitis (AD) in Chinese outpatients is yet to be clarified. Objectives. To investigate population-based prevalence and clinical features of AD in Chinese outpatients. Methods. A multicenter cross-sectional study was conducted in outpatients with eczema or dermatitis from 39 te...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/2568301
更新日期:2016-01-01 00:00:00
abstract::Objective. Our objective is to develop a computerized scheme for liver tumor segmentation in MR images. Materials and Methods. Our proposed scheme consists of four main stages. Firstly, the region of interest (ROI) image which contains the liver tumor region in the T1-weighted MR image series was extracted by using se...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2016/3219068
更新日期:2016-01-01 00:00:00
abstract::The aim of this study was to analyse the circadian behavioural responses of mice carrying a functional knockout of the Per3 gene (Per3(-/-)) to different light : dark (L : D) cycles. Male adult wild-type (WT) and Per3(-/-) mice were kept under 12-hour light : 12-hour dark conditions (12L : 12D) and then transferred to...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2014/170795
更新日期:2014-01-01 00:00:00
abstract:Background:The mechanism of inflammatory reaction after intracerebral hemorrhage remains unclear, which to some extent restrains the therapeutic development of hemorrhagic stroke. The present study attempts to verify whether NLRP6 plays an important role in inflammatory reaction after intracerebral hemorrhage and ident...
journal_title:BioMed research international
pub_type: 杂志文章
doi:10.1155/2020/6182464
更新日期:2020-06-07 00:00:00
abstract::Nowadays, several screening strategies are available to prevent cervical cancer, but inadequate resources, sociocultural barriers, and sampling issues impede their success in low-income countries. To overcome these issues, this study aimed to evaluate the performance of human papillomavirus (HPV) testing from dried ur...
journal_title:BioMed research international
pub_type: 临床试验,杂志文章
doi:10.1155/2015/283036
更新日期:2015-01-01 00:00:00