Pneumolysin expression by streptococcus pneumoniae protects colonized mice from influenza virus-induced disease.

abstract：:Cryphonectria parasitica, the causal agent of chestnut blight is controlled in Europe through natural spread of Cryphonectria hypovirus 1 (CHV1), a mycovirus able to induce hypovirulence to the host. In recent years C. parasitica was reported infecting Azerbaijani population of chestnut, but the presence of CHV1 still...

journal_title：Virology

authors： Forgia M,Isgandarli E,Aghayeva DN,Huseynova I,Turina M

更新日期：2021-01-15 00:00:00

abstract：:The dependence of retroviral replication on cell proliferation was described as early as 1958, although different classes of retroviruses are able to infect non-dividing cells with different efficiencies. For example, the human immunodeficiency virus (HIV) and other lentiviruses infect most non-dividing cells nearly a...

journal_title：Virology

authors： Yamashita M,Emerman M

更新日期：2006-01-05 00:00:00

abstract：:To comprehensively understand the endocytosis of Sapelovirus A (PSV) entry into PK-15 cells, we studied PSV infection in the context of cell perturbations through drug inhibition, siRNA silencing and overexpression of dominant negative (DN) mutants. We showed here that PSV infection of PK-15 cells was unaffected by pr...

journal_title：Virology

authors： Zhao T,Cui L,Yu X,Zhang Z,Shen X,Hua X

更新日期：2019-03-01 00:00:00

abstract：:In mid-January 2016, an outbreak of H7N8 high-pathogenicity avian influenza virus (HPAIV) in commercial turkeys occurred in Indiana. Surveillance within the 10km control zone identified H7N8 low-pathogenicity avian influenza virus (LPAIV) in nine surrounding turkey flocks but no other HPAIV-affected premises. We seque...

journal_title：Virology

authors： Lee DH,Torchetti MK,Killian ML,Swayne DE

更新日期：2017-07-01 00:00:00

abstract：:The measles virus (MV) phosphoprotein (P) and V proteins block the interferon (IFN) response by impeding phosphorylation of the signal transducer and activator of transcription 1 (STAT1) by the Janus kinase 1 (JAK1). We characterized how STAT1 mutants interact with P and JAK1 phosphorylation. Certain mutants of the li...

journal_title：Virology

authors： Devaux P,Priniski L,Cattaneo R

更新日期：2013-09-01 00:00:00

abstract：:About 100 nucleotides of DNA sequence at the 5' noncoding region of the Choristoneura biennis entomopoxvirus spheroidin gene was chemically synthesized and inserted into a vaccinia expression vector, interrupting the vaccinia thymidine kinase gene. When the bacterial beta-galactosidase gene was introduced downstream o...

journal_title：Virology

authors： Pearson A,Richardson C,Yuen L

更新日期：1991-02-01 00:00:00

abstract：:We have investigated the interaction of SV40 virions with polarized monkey kidney epithelial cells. Virions were tagged with biotin to facilitate their detection and were found to retain full infectivity. When polarized Vero C1008 cells were incubated with biotinylated virions followed by a strepavidin-rhodamine conju...

journal_title：Virology

authors： Basak S,Turner H,Compans RW

更新日期：1992-09-01 00:00:00

abstract：:Powassan virus (POWV, Flaviviridae: Flavivirus) is the sole North American member of the tick-borne encephalitis complex and consists of two distinct lineages that are maintained in ecologically discrete enzootic transmission cycles. The underlying genetic mechanisms that lead to niche partitioning in arboviruses are ...

journal_title：Virology

authors： Brackney DE,Brown IK,Nofchissey RA,Fitzpatrick KA,Ebel GD

更新日期：2010-07-05 00:00:00

abstract：:In HSV types 1 and 2, gH forms a noncovalent heterodimer with gL. Previous studies demonstrated that the first 323 amino acids of gH1 and the first 161 amino acids of gL1 are sufficient for gH/gL binding. For gL1, substitution of any of its four cysteine (C) residues (all located within the gH/gL binding region) destr...

journal_title：Virology

authors： Cairns TM,Landsburg DJ,Whitbeck JC,Eisenberg RJ,Cohen GH

更新日期：2005-02-20 00:00:00

abstract：:Human immunodeficiency virus type 1 (HIV-1) exploits multiple host factors during its replication. The REV/RRE-dependent nuclear export of unspliced/partially spliced viral transcripts needs the assistance of host proteins. Recent studies have shown that MOV10 overexpression inhibited HIV-1 replication at various step...

journal_title：Virology

authors： Huang F,Zhang J,Zhang Y,Geng G,Liang J,Li Y,Chen J,Liu C,Zhang H

更新日期：2015-12-01 00:00:00

abstract：:Matrix protein M1 purified from influenza A and B viruses has been analyzed for its ability to specifically interact with cellular proteins by immune coprecipitation and by an in vitro binding assay on nitrocellulose on PVDF membranes. When M1 was mixed with lysates of uninfected cells there was selective binding of h...

journal_title：Virology

authors： Zhirnov OP,Klenk HD

更新日期：1997-09-01 00:00:00

abstract：:The genome of the lytic Pseudomonas putida bacteriophage gh-1 is linear double-stranded DNA containing 37,359 bp with 216-bp direct terminal repeats. Like other members of the T7 group, the gh-1 genome contains regions of high homology to T7 interspersed with nonhomologous regions that contain small open reading frame...

journal_title：Virology

authors： Kovalyova IV,Kropinski AM

更新日期：2003-07-05 00:00:00

abstract：:The nucleic acid of carnation cryptic virus has been identified as double-stranded RNA on the basis of (i) susceptibility to RNase in 0.1 x SSC (SSC = 0.15 M NaCl-0.015 M sodium citrate buffer, pH 7.0) and resistance to RNase in 2 x SSC and to DNase, (ii) reaction with an antiserum containing antibodies to dsRNA, and ...

journal_title：Virology

authors： Lisa V,Boccardo G,Milne RG

更新日期：1981-12-01 00:00:00

abstract：:Adenovirus early region 1A (E1A) products are phosphorylated nuclear oncoproteins which appear to derive transforming activity largely through interactions with cellular proteins including the tumor suppressor p105/Rb-1 and cyclin A (p60cycA), a regulatory subunit associated with p34cdc2 and the related protein kinase...

journal_title：Virology

authors： Dumont DJ,Branton PE

更新日期：1992-07-01 00:00:00

abstract：:Ovine pulmonary carcinoma is a contagious neoplastic disease of sheep which can be transmitted experimentally with cell-free filtrate. Products homologous to structural proteins of type D and type B retroviruses are expressed in the tumors, but an infectious retrovirus has yet to be isolated. Retroviral RNA was isolat...

journal_title：Virology

authors： Hecht SJ,Carlson JO,DeMartin JC

更新日期：1994-07-01 00:00:00

abstract：:Simian-human immunodeficiency virus encoding both reverse transcriptase (RT) and envelope genes of HIV-1 (RT Env SHIV) is important for evaluating biomedical prevention modalities for HIV/AIDS. We describe virological characterization of a clade B RT Env SHIV following infection of macaques via multiple routes. In viv...

journal_title：Virology

authors： Pal R,Galmin L,Pereira LE,Li B,Zhang J,Li D,Francis J,McNicholl JM,Weiss DE,Smith JM

更新日期：2012-10-10 00:00:00

abstract：:The management of hand-foot-and-mouth disease(HFMD) epidemic is difficult due to the frequent emergence of non-EV71 and non-CVA16 enteroviruses and some cases testing negative for HFMD-associated causative agents. To clarify the virus spectrum of mild and severe HFMD, a comprehensive virome analysis of 238 samples was...

journal_title：Virology

authors： Wang C,Zhou S,Xue W,Shen L,Huang W,Zhang Y,Li X,Wang J,Zhang H,Ma X

更新日期：2018-05-01 00:00:00

abstract：:Morphological and molecular changes produced by Autographa californica nuclear polyhedrosis virus (AcMNPV) infection in a permissive cell line, IPLB-SF-21AE (SF-21), of Spodoptera frugiperda and a nonpermissive cell line, FPMI-CF-203 (CF-203), of Choristoneura fumiferana are described. CF-203 cells inoculated with AcM...

journal_title：Virology

authors： Palli SR,Caputo GF,Sohi SS,Brownwright AJ,Ladd TR,Cook BJ,Primavera M,Arif BM,Retnakaran A

更新日期：1996-08-01 00:00:00

abstract：:Most adenovirus transducing vectors have the cytomegalovirus major immediate-early (CMV) or the Rous sarcoma virus long terminal repeat (RSV) promoter driving expression of the transgene. Both of these promoters are highly active in transfection and transduction assays in 293 cells, in which transducing vectors are co...

journal_title：Virology

authors： Schaack J,Allen B,Orlicky DJ,Bennett ML,Maxwell IH,Smith RL

更新日期：2001-12-05 00:00:00

abstract：:The trans-activation-responsive (TAR) element located within the 5' untranslated region of HIV-1 mRNA is the cis-responsive element for Tat, the viral trans-activator protein. Several TAR RNA binding proteins (TRBPs) have been identified in the nuclear extract from HeLa cells as cellular factors required for a full Ta...

journal_title：Virology

authors： Masuda T,Harada S

更新日期：1993-02-01 00:00:00

abstract：:Plasmids containing the E1 region of Ad12 DNA can transform certain rodent cells into oncogenic cells. To study the role of the E1a subregion in the process of oncogenic transformation, Ad12 region E1 mutants carrying deletions in the E1a region were constructed. Deletion mutants pR7 and pR8 affect only the 13 S mRNA ...

journal_title：Virology

authors： Bos JL,Jochemsen AG,Bernards R,Schrier PI,van Ormondt H,van der Eb AJ

更新日期：1983-09-01 00:00:00

abstract：:Hepatitis A virus infection and growth in cultured cells is protracted, cell-type restricted, and generally not accompanied by the appearance of a cytopathic effect, with the exception of some culture-adapted strains. We demonstrate that the non-cytopathic HAV strain HM175/clone 1 can be induced to exhibit a cytopathi...

journal_title：Virology

authors： Wales SQ,Ngo D,Hida K,Kulka M

更新日期：2012-08-15 00:00:00

abstract：:Intact clones containing partial repeats of the genomic components of African cassava mosaic (ACMV DNAs A and B) are infectious when mechanically coinoculated onto Nicotiana benthamiana. Monomeric genomic components may be generated either by homologous recombination or, when two copies of the origin of replication (o...

journal_title：Virology

authors： Stanley J

更新日期：1995-01-10 00:00:00

abstract：:Many plant virus coat proteins have binding sites for divalent cations, particularly calcium. It has been speculated that the purpose of such sites is to ensure that plant viruses release their RNA only in the host cytoplasm which has a low calcium concentration. By comparison to tomato bushy stunt virus, two of the a...

journal_title：Virology

authors： Laakso MM,Heaton LA

更新日期：1993-12-01 00:00:00

abstract：:Porcine reproductive and respiratory syndrome virus (PRRSV) displays notorious genetic, antigenic, and clinical variability. Little is known, however, about the nature and extent of viral variation present within naturally infected animals. By amplifying and cloning the open reading frame 5 gene from tonsils of natura...

journal_title：Virology

authors： Goldberg TL,Lowe JF,Milburn SM,Firkins LD

更新日期：2003-12-20 00:00:00

abstract：:The expression and subcellular location of the 33.6-kDa nonstructural protein NSm of tomato spotted wilt virus (TSWV) was analyzed in Nicotiana rustica plants and protoplasts as a function of time. Immunofluorescent studies in protoplasts isolated from TSWV-infected N. rustica leaves showed that this protein could fir...

journal_title：Virology

authors： Storms MM,Kormelink R,Peters D,Van Lent JW,Goldbach RW

更新日期：1995-12-20 00:00:00

abstract：:When electrophoresed in 0.7% agarose gels, populations of reovirus particles can be resolved into 13 well-defined bands that possess from 0 to 12 projection/spike-associated trimers of protein sigma 1. This state of affairs is not an artifact of purification, of the techniques used to demonstrate it, of aggregation, o...

journal_title：Virology

authors： Larson SM,Antczak JB,Joklik WK

更新日期：1994-06-01 00:00:00

abstract：:Norwalk virus (NV) is the prototype strain of a group of noncultivatable caliciviruses that infect humans and cause outbreaks of epidemic acute nonbacterial gastroenteritis. The NV virion is composed of 180 copies of a single structural protein that, when expressed in insect cells infected with a recombinant baculovir...

journal_title：Virology

authors： Hardy ME,Tanaka TN,Kitamoto N,White LJ,Ball JM,Jiang X,Estes MK

更新日期：1996-03-01 00:00:00

abstract：:DI7 is a defective interfering RNA derived from RNA 2 of tobacco rattle tobravirus (TRV) isolate PpK20. Tobacco was transformed with DI7 cDNA fused to the CaMV 35S promoter. Upon infection of the transgenic plants with TRV isolate PpK20 or the serologically unrelated isolate PaY4, the transgenic DI7 RNA started to acc...

journal_title：Virology

authors： Visser PB,Brown DJ,Brederode FT,Bol JF

更新日期：1999-10-10 00:00:00

abstract：:We have used a microinjection approach to identify a domain of the simian virus 40 (SV40) structural proteins Vp2 and Vp3(Vp2/3) responsible for their nuclear transport. By using both synthetic peptides, containing small regions of Vp2/3 conjugated to bovine serum albumin (BSA), and beta-galactosidase-Vp3 fusion prote...

journal_title：Virology

authors： Clever J,Kasamatsu H

更新日期：1991-03-01 00:00:00