The hunger genes: pathways to obesity.

Abstract:

:The global rise in the prevalence of obesity and associated co-morbidities such as type 2 diabetes, cardiovascular disease, and cancer represents a major public health concern. The biological response to increased consumption of palatable foods or a reduction in energy expenditure is highly variable between individuals. A more detailed mechanistic understanding of the molecular, physiological, and behavioral pathways involved in the development of obesity in susceptible individuals is critical for identifying effective mechanism-based preventative and therapeutic interventions.

journal_name

Cell

journal_title

Cell

authors

van der Klaauw AA,Farooqi IS

doi

10.1016/j.cell.2015.03.008

subject

Has Abstract

pub_date

2015-03-26 00:00:00

pages

119-132

issue

1

eissn

0092-8674

issn

1097-4172

pii

S0092-8674(15)00261-5

journal_volume

161

pub_type

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