Abstract:
:The global rise in the prevalence of obesity and associated co-morbidities such as type 2 diabetes, cardiovascular disease, and cancer represents a major public health concern. The biological response to increased consumption of palatable foods or a reduction in energy expenditure is highly variable between individuals. A more detailed mechanistic understanding of the molecular, physiological, and behavioral pathways involved in the development of obesity in susceptible individuals is critical for identifying effective mechanism-based preventative and therapeutic interventions.
journal_name
Celljournal_title
Cellauthors
van der Klaauw AA,Farooqi ISdoi
10.1016/j.cell.2015.03.008subject
Has Abstractpub_date
2015-03-26 00:00:00pages
119-132issue
1eissn
0092-8674issn
1097-4172pii
S0092-8674(15)00261-5journal_volume
161pub_type
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