Abstract:
:Activation of plasma membrane calcium channels by depletion of endoplasmic reticulum (ER) calcium stores is important for calcium entry in many cell types. Park et al. (2009) now show that direct binding of the ER protein STIM to tetramers of the Orai1 calcium channel in the plasma membrane triggers opening of this channel.
journal_name
Celljournal_title
Cellauthors
Clapham DEdoi
10.1016/j.cell.2009.02.022subject
Has Abstractpub_date
2009-03-06 00:00:00pages
814-6issue
5eissn
0092-8674issn
1097-4172pii
S0092-8674(09)00198-6journal_volume
136pub_type
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