Effect of various prokinetic agents on post Roux-en-Y gastric emptying. Experimental and clinical observations.

abstract：BACKGROUND:The prevalence of advanced liver disease and its complications may be on the rise within the Medicare population. The study aim was trend assessment for prevalence, mortality and resource utilization of patients with advanced liver disease. METHODS:A retrospective, cross-sectional design was used to analyze...

journal_title：Digestive diseases and sciences

authors： Otgonsuren M,Henry L,Hunt S,Venkatesan C,Mishra A,Younossi ZM

更新日期：2015-02-01 00:00:00

abstract：:Gastroesophageal reflux may be responsible for atypical symptoms such as chronic cough and hoarseness. Our aim was to evaluate and treat patients with severe gastroesophageal reflux and chronic cough or hoarseness with intensive antireflux therapy. Twenty-seven patients with typical heartburn symptoms in addition to s...

journal_title：Digestive diseases and sciences

authors： Waring JP,Lacayo L,Hunter J,Katz E,Suwak B

更新日期：1995-05-01 00:00:00

abstract：:Capsaicin-sensitive afferent nerves (CSANs) are involved in the protection of gastric mucosa. To clarify the role of CSANs in human Helicobacter pylori-negative or -positive chronic gastritis, after bacterium detection by rapid urease test, (14)C urea breath test, and specific histological staining, the immunodistribu...

journal_title：Digestive diseases and sciences

authors： Dömötör A,Kereskay L,Szekeres G,Hunyady B,Szolcsányi J,Mózsik G

更新日期：2007-02-01 00:00:00

abstract：:Clinical features and liver biopsy findings were studied in six patients with nonalcoholic steatohepatitis associated with hyalin. A comparative study was made on the ultrastructure of the hyalin in one patient with nonalcoholic steatohepatitis and in one patient with alcoholic hepatitis. The patients, all over 50 yea...

journal_title：Digestive diseases and sciences

authors： Itoh S,Matsuo S,Ichinoe A,Yamaba Y,Miyazawa M

更新日期：1982-04-01 00:00:00

abstract：BACKGROUND:Corticotropin-releasing factor (CRF) peptides exert profound effects on the secretomotor function of the gastrointestinal tract. Nevertheless, despite the presence of CRF peptides and receptors in colonic tissue, their influence on colonic blood flow (CBF) is unknown. AIM:To determine the effect and mechani...

journal_title：Digestive diseases and sciences

authors： Akiba Y,Kaunitz JD,Million M

更新日期：2015-04-01 00:00:00

abstract：:The synthetic substrate cholyl-PABA, developed by conjugating cholic acid with paraaminobenzoic acid, is hydrolyzed by the bacterial enzyme cholyl hydrolase to release free PABA. This study aimed to evaluate whether quantitating urinary excretion of PABA after oral administration of cholyl-PABA can detect small intest...

journal_title：Digestive diseases and sciences

authors： Bardhan PK,Feger A,Kogon M,Muller J,Gillessen D,Beglinger C,Gyr N

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND AND AIM:The liver has a high capacity of its regeneration. Most hepatic cells are quiescent unless otherwise stimulated such as their injury or ablation. A previous study suggest that pre-activated hepatic cells have a positive effect on their regeneration. In this study, we examined whether the pre-activate...

journal_title：Digestive diseases and sciences

authors： Arioka Y,Ito H,Ando T,Ogiso H,Hirata A,Hara A,Seishima M

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Mast cells (MCs), PAR2 and TRPV1, play a key role in the regulation of visceral pain. Several studies have found that probiotics regulate visceral sensitivity. AIMS:The purpose of the current study was to explore the role of MC-PAR2-TRPV1 in VH and the mechanism of VSL#3 in a rat model of VH. METHODS:A tot...

journal_title：Digestive diseases and sciences

authors： Li YJ,Dai C,Jiang M

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND AND AIM:Aberrant methylation of specific genes is frequent event in hepatocellular carcinoma (HCC). Our present study aims to explore the methylation levels of acid phosphatase locus 1 (ACP1), bone morphogenetic protein 4 (BMP4), and testis-specific protein, Y-encoded-like 5 (TSPYL5) and their potential clin...

journal_title：Digestive diseases and sciences

authors： Qiu X,Hu B,Huang Y,Deng Y,Wang X,Zheng F

更新日期：2016-01-01 00:00:00

abstract：:The susceptibility to sepsis in obstructive jaundice may be related to bacterial translocation (BT) from the gastrointestinal tract. We evaluated BT to visceral organs and morphological changes of the intestinal mucosa in a rat model of obstructive jaundice. Animals were randomly divided into two groups: in group A th...

journal_title：Digestive diseases and sciences

authors： Sileri P,Morini S,Sica GS,Schena S,Rastellini C,Gaspari AL,Benedetti E,Cicalese L

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Sorafenib is a proven first-line treatment recommended for hepatocellular carcinoma (HCC) patients with portal vein invasion (PVI). However, multiple treatment modalities are used in clinical practice as a first-line option. This study is a prospective, observational, multicenter, cohort study evalu...

journal_title：Digestive diseases and sciences

authors： Sinn DH,Lee HW,Paik YH,Kim DY,Kim YJ,Kim KM,Bae SH,Kim JH,Seo YS,Jang JY,Jang BK,Yim HJ,Kim HJ,Lee BS,Kim BH,Kim IH,Cho EY,Lee JI,Suh KS

更新日期：2021-01-01 00:00:00

abstract：:The association of chronic intestinal pseudoobstruction with ophthalmoplegia has been reported previously in visceral myopathies. We report a case of this association in which muscle mitochondria had a crystalline appearance, a dense core, and decreased cytochrome c oxidase and succinate cytochrome c reductase activit...

journal_title：Digestive diseases and sciences

authors： Li V,Hostein J,Romero NB,Marsac C,Mezin P,Bost R,Degoul F,Fardeau M,Fournet J

更新日期：1992-03-01 00:00:00

abstract：INTRODUCTION:The C-31G polymorphism in the survivin promoter could de-repress the cell-cycle-dependent transcription of the human survivin gene, resulting in overexpression of survivin. This survivin mutation has only been studied on cervical carcinoma. However, no study has ever been conducted to evaluate the effect o...

journal_title：Digestive diseases and sciences

authors： Yang L,Zhu H,Zhou B,Gu H,Yan H,Tang N,Dong H,Sun Q,Cong R,Chen G,Wang B

更新日期：2009-05-01 00:00:00

abstract：:Gastric distension has been used to evaluate gastric sensory function in humans, but the methodology is poorly validated and studies in vivo comparing different distension protocols are lacking. We aimed to compare the influence of the mode of gastric distension on sensation and gastric compliance utilizing a barostat...

journal_title：Digestive diseases and sciences

authors： Holtmann G,Gschossmann J,Guerra G,Goebell H,Talley NJ

更新日期：1995-12-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) is caused by a mechanically defective lower esophageal sphincter (LES) and may be worsened by impaired esophageal peristalsis. The aim of this study was to evaluate the efficacy of medical treatment depending on the function of the LES and esophageal peristalsis. We studied 128 G...

journal_title：Digestive diseases and sciences

authors： Klaus A,Gadenstaetter M,Mühlmann G,Kirchmayr W,Profanter C,Achem SR,Wetscher GJ

更新日期：2003-09-01 00:00:00

abstract：:The value of intense nutritional support in inflammatory bowel disease is still debated. Claims have been made that total enteral nutrition is as effective as total parental nutrition. In this review, the use of parenteral and enteral nutritional support as primary therapy in patients with inflammatory bowel disease h...

journal_title：Digestive diseases and sciences

authors： Wu S,Craig RM

更新日期：1995-04-01 00:00:00

abstract：:It is known that the muscularis mucosae and mucosa are not pharmacologically homogeneous throughout the rat colon. The aim of this study was to simultaneously characterize all three neurokinin (NK) receptors in the muscularis mucosae and mucosa along the length of the rat colon. Strips of proximal, mid, and distal col...

journal_title：Digestive diseases and sciences

authors： Appleyard CB,Morales M,Percy WH

更新日期：2006-03-01 00:00:00

abstract：:Health-care-seeking behaviors related to bowel complaints may vary between ethnic groups. A survey of a nonpatient population in El Paso, Texas, was conducted in order to examine differences in health care behavior related to bowel dysfunction, and in the perception of health and bowel function, in Hispanics and non-H...

journal_title：Digestive diseases and sciences

authors： Zuckerman MJ,Guerra LG,Drossman DA,Foland JA,Gregory GG

更新日期：1996-01-01 00:00:00

abstract：:Fish oil (a very long chain triglycerides, VLCT) has received much attention because of its favorable metabolic properties; however, its effect on gastrointestinal function has not been studied. We investigated the effects of intraduodenally administered VLCT on gut-hormone release [cholecystokinin (CCK), neurotensin,...

journal_title：Digestive diseases and sciences

authors： Jonkers IJ,Ledeboer M,Steens J,Smelt AH,Masclee AA

更新日期：2000-09-01 00:00:00

abstract：:A sustained increase in cytosolic Ca2+ can damage gastric mucosal cells. The present study has examined the role of Ca2+ in thromboxane B2 (TXB2)-mediated damage of rabbit isolated gastric mucosal cells. Cells were isolated from rabbit oxyntic mucosa by collagenase-EDTA digestion. Cell metabolic activity and cell dama...

journal_title：Digestive diseases and sciences

authors： Wong HM,Soper BD,Tepperman BL

更新日期：1995-09-01 00:00:00

abstract：:We studied intraesophageal pressure changes in patients with symptoms of gastroesophageal reflux and an abnormal 24-hr pH monitoring record (N = 52). Our method was simultaneous esophageal manometry and pH monitoring. We observed a three-component esophageal manometric sequence (EMS). When this sequence recurred over ...

journal_title：Digestive diseases and sciences

authors： Shay SS,Eggli D,Oliver G,Peura DA,Johnson LF

更新日期：1989-09-01 00:00:00

abstract：:Positive findings on capsule endoscopy (CE) often prompt a follow-up procedure with therapeutic intent. Our purpose was to review the therapeutic yield of subsequent procedural interventions based on positive CE findings. The medical records of all patients who underwent CE between June 2002 and February 2005 for obsc...

journal_title：Digestive diseases and sciences

authors： Baichi MM,Arifuddin RM,Mantry PS

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:There is a large Barrett's esophagus patient population undergoing endoscopic surveillance. Methods to stratify patients into higher and lower risk groups may enable more varied surveillance intervals for patients with non-dysplastic Barrett's esophagus that could optimize use of endoscopy resources. OBJECT...

journal_title：Digestive diseases and sciences

authors： Kunzmann AT,Coleman HG,Johnston BT,Turkington RC,McManus D,Anderson LA,Thrift AP

更新日期：2020-07-20 00:00:00

abstract：:Fructose and lactose malabsorption are characterized by impaired duodenal fructose transport or by the deficiency of mucosal lactase, respectively. As a consequence, the nonabsorbed saccharides reach the colon, where they are broken down by bacteria to short fatty acids, CO2, and H2. Bloating, cramps, osmotic diarrhea...

journal_title：Digestive diseases and sciences

authors： Ledochowski M,Widner B,Sperner-Unterweger B,Propst T,Vogel W,Fuchs D

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Percutaneous catheter drainage (PCD) performed pro-actively for collections in acute pancreatitis (AP) is associated with better outcomes. However, there are only a few studies describing this protocol. AIM:We aimed to evaluate an aggressive PCD protocol. METHODS:Consecutive patients with AP who underwent ...

journal_title：Digestive diseases and sciences

authors： Gupta P,Gupta J,Kumar C,Samanta J,Mandavdhare H,Sharma V,Sinha SK,Gupta V,Yadav TD,Dutta U,Kochhar R

更新日期：2020-12-01 00:00:00

abstract：:In situ steady-state, single-pass small intestine perfusions in rats were carried out to compare the effect of the bicarbonate and citrate World Health Organization oral rehydration solutions and a base precursor-free solution on intestinal water and electrolyte transport after inducing intestinal secretion with purif...

journal_title：Digestive diseases and sciences

authors： Rolston DD,Mathan VI

更新日期：1992-01-01 00:00:00

abstract：:Rebamipide, a gastroprotective drug, is a compound selected from over 500 amino acid analogs of 2(1H)-quinolinone tested for gastroprotective action and for efficacy to heal experimental gastric ulcers. This drug stimulates prostaglandin generation in gastric mucosa and improves not only the speed but also the quality...

journal_title：Digestive diseases and sciences

authors： Arakawa T,Kobayashi K,Yoshikawa T,Tarnawski A

更新日期：1998-09-01 00:00:00

abstract：:Our aim was to compare standard liver function tests (serum bilirubin, serum albumin and prothrombin concentration), with lidocaine and monoethylglycinexylidide pharmacokinetic parameters, after oral lidocaine administration, to assess hepatic function of cirrhotic individuals. Twenty-one consecutive cirrhotic patient...

journal_title：Digestive diseases and sciences

authors： Muñoz AE,Miguez C,Rubio M,Bartellini M,Levi D,Podestá A,Niselman V,Terg R

更新日期：1999-04-01 00:00:00

abstract：:This study aimed at establishment of adequate evaluation of intestinal viability before release of the strangulated intestine by measuring electrical properties. In rats a 20-cm segment of the distal ileum and mesentery was strangulated. The intestine was strangulated for 0, 2, 15, 45, 90, and 120 min. The conductance...

journal_title：Digestive diseases and sciences

authors： Matsuo H,Hirose H,Mori Y,Takagi H,Iwata H,Yamada T,Sakamoto K,Yasumura M

更新日期：2004-04-01 00:00:00

abstract：:We describe a 28-yr-old woman who presented with severe, recurrent cholangitis due to Caroli's disease in association with congenital hepatic fibrosis. Cystic dilatation of the segmental bile ducts was diffuse, but predominated in the right lobe and left medial segment of the liver. Extended right lobectomy was follow...

journal_title：Digestive diseases and sciences

authors： Ramond MJ,Huguet C,Danan G,Rueff B,Benhamou JP

更新日期：1984-04-01 00:00:00