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Cycling, a manometric phenomenon due to repetitive episodes of gastroesophageal reflux and clearance.

Abstract：

:We studied intraesophageal pressure changes in patients with symptoms of gastroesophageal reflux and an abnormal 24-hr pH monitoring record (N = 52). Our method was simultaneous esophageal manometry and pH monitoring. We observed a three-component esophageal manometric sequence (EMS). When this sequence recurred over and over, we termed this phenomenon "cycling." We found cycling in 35% of the patients (18/52). Those with cycling had lower basal LES pressures, more acid exposure, and an increased incidence of endoscopic esophagitis. That cycling resulted from repeated reflux events and their esophageal clearance was documented by scintigraphy during simultaneous manometry and pH monitoring (N = 7 patients). Cycling was found on the routine esophageal manometry record of 25% of symptomatic patients (N = 112) with an abnormal 24-hr pH score. In conclusion, cycling represents an esophageal manometric phenomenon due to repetitive reflux events. Its recognition during esophageal manometry may denote a severe reflux diathesis.

journal_name

Dig Dis Sci

journal_title

Digestive diseases and sciences

authors

Shay SS,Eggli D,Oliver G,Peura DA,Johnson LF

doi

10.1007/BF01538066

subject

Has Abstract

pub_date

1989-09-01 00:00:00

pages

1340-8

issue

9

eissn

0163-2116

issn

1573-2568

journal_volume

34

pub_type

杂志文章

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