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Experimental studies to estimate the intestinal viability in a rat strangulated ileus model using a dielectric parameter.

Abstract：

:This study aimed at establishment of adequate evaluation of intestinal viability before release of the strangulated intestine by measuring electrical properties. In rats a 20-cm segment of the distal ileum and mesentery was strangulated. The intestine was strangulated for 0, 2, 15, 45, 90, and 120 min. The conductance and capacitance obtained by impedance analyzer were used to calculate tan(delta)m in the strangulated intestine. ATP was measured as well. In another experiment, after various periods of strangulation, tan(delta)m was measured just before release of the strangulation. Rats were divided into Group A (survived for 7 days) and Group D (died within 7 days). There was a positive correlation between tan(delta)m and ATP levels (P < 0.01). And tan(delta)m was significantly greater in Group A than in Group D (P < 0.05). There were no deaths at a tan(delta)m value of 2.36 or more and no survivors at a tan(delta)m of less than 2.20 except for one rat. These results suggested that tan(delta)m may be a useful index of the viability of the strangulated intestine before reperfusion.

journal_name

Dig Dis Sci

journal_title

Digestive diseases and sciences

authors

Matsuo H,Hirose H,Mori Y,Takagi H,Iwata H,Yamada T,Sakamoto K,Yasumura M

doi

10.1023/b:ddas.0000026310.71607.4c

subject

Has Abstract

pub_date

2004-04-01 00:00:00

pages

633-8

issue

4

eissn

0163-2116

issn

1573-2568

journal_volume

49

pub_type

杂志文章

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