Hypermethylation of ACP1, BMP4, and TSPYL5 in Hepatocellular Carcinoma and Their Potential Clinical Significance.

abstract：BACKGROUND AND AIM:Simultaneous dilatation of the common bile duct and pancreatic duct, "double-duct sign" (DDS), is an ominous finding concerning for pancreaticobiliary malignancy. Little evidence exists to guide the initial evaluation and subsequent follow-up for patients with DDS in the absence of jaundice or focal ...

journal_title：Digestive diseases and sciences

authors： Cohen J,Sawhney MS,Pleskow DK,Chuttani R,Patel NJ,Sheridan J,Berzin TM

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:Peyer's patches (PPs), which are covered by specialized follicle-associated epithelium (FAE) including M cells, play a central role in immune induction in the gastrointestinal tract. This study is to investigate a new molecule to characterize PPs. METHODS:We generated a monoclonal antibody (mAb 10-15-3-3) t...

journal_title：Digestive diseases and sciences

authors： Tokuhara D,Nochi T,Matsumura A,Mejima M,Takahashi Y,Kurokawa S,Kiyono H,Yuki Y

更新日期：2014-11-01 00:00:00

abstract：:Vitamin D deficiency is frequently observed in patients with Crohn's disease and may be associated with an increased risk of development of metabolic bone disease. To estimate the incidence of metabolic bone disease by noninvasive methods, 31 patients (17-75 years old) with Crohn's disease and low 25-hydroxyvitamin D ...

journal_title：Digestive diseases and sciences

authors： Vogelsang H,Ferenci P,Woloszczuk W,Resch H,Herold C,Frotz S,Gangl A

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Data on alcohol-related HCC are limited. AIMS:Our aim was to describe the incidence, management, and prognosis of alcohol compared to Hepatitis C (HCV)-related HCC at a national level. METHODS:Incident cases of HCC were identified in French healthcare databases between 2009 and 2012 and analyzed retrospect...

journal_title：Digestive diseases and sciences

authors： Costentin CE,Sogni P,Falissard B,Barbare JC,Bendersky N,Farges O,Goutte N

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:The age to stop screening or surveillance colonoscopy is not well established, and unplanned hospital use after colonoscopy in the elderly is not well understood. AIMS:To evaluate unplanned emergency department (ED) visits and hospitalization in patients over 75 within 7 days of outpatient colonoscopy. MET...

journal_title：Digestive diseases and sciences

authors： Grossberg LB,Papamichael K,Leffler DA,Sawhney MS,Feuerstein JD

更新日期：2020-07-01 00:00:00

abstract：:Many physiological factors can alter gastric emptying, and the role of gastric emptying in functional dyspepsia is controversial. The aim of this study was to assess the effects of different factors (age, sex, the degree of dyspeptic and irritable bowel symptoms, lactase deficiency, smoking habits, the use of antiinfl...

journal_title：Digestive diseases and sciences

authors： Koskenpato J,Kairemo K,Korppi-Tommola T,Färkkilä M

更新日期：1998-06-01 00:00:00

abstract：:Eosinophilic gastroenteritis is a rare benign disease characterized by tissue eosinophilic infiltration that may involve several digestive tract layers. Also known as allergic, or eosinophilic allergic, gastroenteropathy, it usually involves the stomach and small intestine: rarely the colon. It may or may not be accom...

journal_title：Digestive diseases and sciences

authors： Méndez-Sánchez N,Chávez-Tapia NC,Vazquez-Elizondo G,Uribe M

更新日期：2007-11-01 00:00:00

abstract：:Interferon treatment of chronic hepatitis C virus infection is successful in a minority of patients. The sequence of the interferon sensitivity determining region (ISDR) of the NS5A protein may determine the outcome of therapy in patients infected with HCV genotype 1. To determine whether IFN treatment caused selectio...

journal_title：Digestive diseases and sciences

authors： Paterson M,Laxton C,Goldin RD,Ackrill AM,Foster GR

更新日期：2001-07-01 00:00:00

abstract：:Since granulocyte elastase has been shown to be involved in the pathogenesis of gastric mucosal lesion formation induced by nonsteroidal antiinflammatory drugs, inhibition of granulocyte elastase release from neutrophils may be useful in the prevention of these lesions. The objective of this study was to determine whe...

journal_title：Digestive diseases and sciences

authors： Murakami K,Okajima K,Harada N,Isobe H,Okabe H

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Diagnosis of eosinophilic esophagitis (EoE) requires manual quantification of tissue eosinophils. Eosinophil peroxidase (EPX) is an eosinophil-specific, cytoplasmic granule protein released during degranulation. AIMS:The objective of this study was to evaluate image analysis of EPX immunohistochemistry as a...

journal_title：Digestive diseases and sciences

authors： Wright BL,Doyle AD,Shim KP,Pai RK,Barshow SM,Horsley-Silva JL,Luo H,Rank MA,Jacobsen EA,Katzka DA,Kita H,Dellon ES

更新日期：2020-04-04 00:00:00

abstract：:The effect of ischemia-reperfusion and 48-hr fasting on apoptosis was characterized in rat gastric mucosa and compared to small intestinal mucosa. Under halothane anesthesia, the celiac artery or superior mesenteric artery in the rat was occluded for 60 min followed by reperfusion. Occlusion of the celiac artery reduc...

journal_title：Digestive diseases and sciences

authors： Fukuyama K,Iwakiri R,Noda T,Kojima M,Utsumi H,Tsunada S,Sakata H,Ootani A,Fujimoto K

更新日期：2001-03-01 00:00:00

abstract：:Magnifying videoendoscopic observation of a minute lesion with a single IIIL type cryptal orifice was reported. This minute lesion was a single-gland adenoma accompanied histopathologically by a bud of adenomatous gland and was located in the upper part of the mucosa. This finding regarding a pit pattern should make p...

journal_title：Digestive diseases and sciences

authors： Tamura S,Nakajo K,Kitamura M,Kamiji I,Onishi S

更新日期：2002-10-01 00:00:00

abstract：:Concordance between gram-negative enteric and other toxin-producing bacteria in blood and stool culture, endotoxin (lipopolysaccharide), and interleukin-6 (IL-6) was measured in 60 preterm infants (600-1600 g) as a clinical index in neonatal necrotizing enterocolitis (NEC). E. coli, Klebsiella, Enterobacter, and Clost...

journal_title：Digestive diseases and sciences

authors： Duffy LC,Zielezny MA,Carrion V,Griffiths E,Dryja D,Hilty M,Rook C,Morin F 3rd

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Systemic sclerosis (SS) patients with severe esophageal affection have impaired peristalsis. However, motor function evaluated in vivo by manometry and fluoroscopy does not provide detailed information about the individual contraction cycles. AIMS:To apply, for the first time in gastrointestinal (GI) patien...

journal_title：Digestive diseases and sciences

authors： Gregersen H,Villadsen GE,Liao D

更新日期：2011-12-01 00:00:00

abstract：:We have developed an improved semiconductor recording probe for monitoring motility of the upper small intestine in humans. The probe consists of six ultraminiature silicon pressure sensors spaced 10 cm apart and encased in a flexible polyurethane sheath. The probe is small [2.67 mm (8F) diameter], is easily passed tr...

journal_title：Digestive diseases and sciences

authors： Mathias JR,Sninsky CA,Millar HD,Clench MH,Davis RH

更新日期：1985-02-01 00:00:00

abstract：:In previous open studies, misoprostol and metronidazole reduced nonsteroidal anti-inflammatory drug-induced intestinal permeability changes and inflammation respectively. We assessed the effects of indomethacin treatment (50 mg three times a day) for one week with either coadministered metronidazole (400 mg twice a da...

journal_title：Digestive diseases and sciences

authors： Davies GR,Wilkie ME,Rampton DS

更新日期：1993-03-01 00:00:00

abstract：:A newly developed enzymatic method for determining urinary 3 alpha-sulfated bile acids was used to measure serum 3 alpha-sulfated bile acid levels in 114 patients with hepatobiliary diseases and 56 healthy subjects. The lowest measurable amount of the 3 alpha-sulfated bile acids was 0.5 mumol/liter. The standard curve...

journal_title：Digestive diseases and sciences

authors： Kato T,Yoneda M,Nakamura K,Makino I

更新日期：1996-08-01 00:00:00

abstract：:Duodenal ulcer has not been observed in full-heritage Pima Indians, while gastric cancer is relatively frequent. To investigate possible underlying factors for this phenomenon, we determined gastric acid output, gastric emptying rate, and plasma levels of gastrin, pepsinogen I, and pepsinogen II in apparently healthy ...

journal_title：Digestive diseases and sciences

authors： Sasaki H,Nagulesparan M,Samloff IM,Straus E,Sievers ML,Dubois A

更新日期：1984-09-01 00:00:00

abstract：:Congenital gastric outlet anomalies are rarely seen defects resulting from early embryologic development of foregut. We report a case of congenital pyloric outlet anomaly in a 60-year-old man with mild postprandial epigastric discomfort of approximately 3 months' duration. Endoscopic examination of the stomach showed ...

journal_title：Digestive diseases and sciences

authors： Uraz S,Aygün C,Konduk T,Celebi A,Sentürk O,Hülagü S

更新日期：2007-04-01 00:00:00

abstract：:The purpose of the present study was to investigate the prognostic role of severe hypoxemia on admission as an independent risk factor of pulmonary complications and mortality in patients with acute pancreatitis. Pulmonary complications were studied in 166 previously healthy patients with acute pancreatitis. Forty-eig...

journal_title：Digestive diseases and sciences

authors： Polyzogopoulou E,Bikas C,Danikas D,Koutras A,Kalfarentzos F,Gogos CA

更新日期：2004-01-01 00:00:00

abstract：:A detailed comparison was made of the bile acid composition in gallstones (brown pigment stones) and paired bile and liver from both affected and unaffected lobes by gallstones, which were taken at operation from 16 patients with hepatolithiasis, with the aim of elucidating whether stone formation is derived from poss...

journal_title：Digestive diseases and sciences

authors： Shoda J,Tanaka N,He BF,Matsuzaki Y,Osuga T,Miyazaki H

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND AND AIM:The liver has a high capacity of its regeneration. Most hepatic cells are quiescent unless otherwise stimulated such as their injury or ablation. A previous study suggest that pre-activated hepatic cells have a positive effect on their regeneration. In this study, we examined whether the pre-activate...

journal_title：Digestive diseases and sciences

authors： Arioka Y,Ito H,Ando T,Ogiso H,Hirata A,Hara A,Seishima M

更新日期：2015-06-01 00:00:00

abstract：:Ten patients were prospectively studied using 99mTc-PIPIDA imaging to evaluate the effects of fasting and parenteral alimentation on gallbladder function. Three of ten patients had initial nonvisualization of the gallbladder for up to 2 hr, yet had normal visualization on repeat imaging performed after resumption of o...

journal_title：Digestive diseases and sciences

authors： Potter T,McClain CJ,Shafer RB

更新日期：1983-08-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to determine the potential for pancreatic calcification in autoimmune pancreatitis by investigating osteopontin and CD44 expression. METHODS:Human pancreatic tissues in normal pancreas, chronic pancreatitis, and autoimmune pancreatitis were obtained from the surgical specime...

journal_title：Digestive diseases and sciences

authors： Takada H,Nakazawa T,Ohara H,Ando T,Hayashi K,Naito I,Okumura F,Tanaka H,Yamada T,Takahashi S,Joh T

更新日期：2009-04-01 00:00:00

abstract：:Cirrhotic patients with hepatocellular carcinoma (HCC) frequently develop hepatic encephalopathy. Metabolic etiology of encephalopathy is less often considered in these patients. Although paraneoplastic hypercalcemia may be associated with several malignant tumors, it has also been described in HCC [1-4], and may caus...

journal_title：Digestive diseases and sciences

authors： Tudela P,Soldevila B,Mòdol JM,Domènech E

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Alcoholic hepatitis (AH) is a serious clinical syndrome often associated with muscle wasting. Myostatin, a member of the transforming growth factor-β superfamily, has been studied in diseases with muscle wasting; however, the role of myostatin in AH is unknown. AIMS:To investigate the association between my...

journal_title：Digestive diseases and sciences

authors： Shamseddeen H,Madathanapalli A,Are VS,Shah VH,Sanyal AJ,Tang Q,Liang T,Gelow K,Zimmers TA,Chalasani N,Desai AP

更新日期：2020-10-19 00:00:00

abstract：:After gastrectomy, Roux-Y limb reconstruction leads to duodenojejunal motor disturbances. Because motilin and pancreatic polypeptide (PP) play a role in the regulation of digestive motility, their plasma concentrations were determined in rats after Roux-Y gastrectomy. Three months after a distal Roux-Y gastrectomy, co...

journal_title：Digestive diseases and sciences

authors： Le Blanc-Louvry I,Ducrotte P,Chayvialle JA,Coquerel A,Michot F,Ténière P

更新日期：2000-08-01 00:00:00

abstract：:With the increasing incidence of hepatocellular carcinoma (HCC) and its high mortality rates, effective treatment options are of urgent need, preferably in a multidisciplinary setting. In the management of those patients, interventional radiologists play a key role. In this article, we reviewed the current literature ...

journal_title：Digestive diseases and sciences

authors： Vogl TJ,Gruber-Rouh T

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:The gut is an important target organ of injury during critically ill conditions. Although Gram staining is a common and quick method for identifying bacteria, its clinical application has not been fully evaluated in critically ill conditions. AIMS:This study's aims were to identify patterns of Gram-stained ...

journal_title：Digestive diseases and sciences

authors： Shimizu K,Ogura H,Tomono K,Tasaki O,Asahara T,Nomoto K,Morotomi M,Matsushima A,Nakahori Y,Yamano S,Osuka A,Kuwagata Y,Sugimoto H

更新日期：2011-06-01 00:00:00

abstract：:This study determined how the luminal surface hydrophobicity and transmucosal potential difference (PD) of canine gastric mucosa changed during the recovery period after the tissue was challenged with acidified aspirin. Luminal aspirin reduced both the contact angle and PD of mucosae incubated in Ussing chambers. Afte...

journal_title：Digestive diseases and sciences

authors： Goddard PJ,Lichtenberger LM

更新日期：1995-06-01 00:00:00