Abstract:
:The value of intense nutritional support in inflammatory bowel disease is still debated. Claims have been made that total enteral nutrition is as effective as total parental nutrition. In this review, the use of parenteral and enteral nutritional support as primary therapy in patients with inflammatory bowel disease has been critically evaluated. Most studies have been uncontrolled and nonrandomized with short-term follow-up. The literature does suggest, however, that intense nutritional support may have an adjunctive role to drug therapy in achieving remission in Crohn's disease, especially in corticosteroid-refractory patients. Nutritional support has a lesser role in chronic ulcerative colitis, except for assistance in pre- and postoperative management. The data do not support one variety of nutritional support over another, although enteral support should be used if possible, as it is less costly and potentially less complicated.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Wu S,Craig RMdoi
10.1007/BF02064990subject
Has Abstractpub_date
1995-04-01 00:00:00pages
843-52issue
4eissn
0163-2116issn
1573-2568journal_volume
40pub_type
杂志文章,评审abstract::A novel peptide, submandibular gland peptide-T (SGP-T), which reduces allergen-induced hypotension, was examined for effects on intestinal anaphylaxis. Hooded-Lister rats were sensitized to egg albumin and prepared for the measurement of in vivo myoelectric activity of the jejunum. The disruption of migrating myoelect...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1018847608184
更新日期:1997-11-01 00:00:00
abstract::The effect of smoking on interdigestive gastrointestinal motility is little studied but may play a role in gastrointestinal morbidity. We studied gastroduodenal motility in 10 volunteers (five smokers and five nonsmokers) using a water-perfused pressure catheter. A pH probe was placed in the duodenal bulb. Baseline mo...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF02220449
更新日期:1995-12-01 00:00:00
abstract::Gallbladder dynamics, cholecystokinin (CCK), and pancreatic polypeptide (PP) release were studied in 14 patients with chronic pancreatitis (CP) (2 females, 12 males; age range 24-56 years) and 12 control subjects (4 females, 8 males, 21-50 years). On day 1, gallbladder contractility was investigated after ceruletide i...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01316503
更新日期:1993-03-01 00:00:00
abstract::Somatostatin analog SMS 201-995 causes a dose-related suppression of the release and/or action of several gastrointestinal hormones and impairs several anterior pituitary functions. Some patients with illness involving abnormal hormonal activity have responded to treatment with SMS 201-995, including resolution of sev...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01296623
更新日期:1991-12-01 00:00:00
abstract::Chemiluminescence (CL) analysis of monocytes and polymorphonuclear cells (PMNs) was performed on 13 patients with Crohn's disease (CD) and 10 healthy volunteers. The percentages of monocyte populations in mononuclear cells obtained from the patients with CD were greater than those from the healthy volunteers, but the ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01535990
更新日期:1988-08-01 00:00:00
abstract::The synthetic prostanoid, Ro 22-6923, was studied for its effects on canine gastric secretion. Histamine-stimulated acid secretion was inhibited for up to 8 hr after an orally administered dose of 0.25 mg/kg Ro 22-6923. In the Amdrup (modified Pavlov) pouch model, Ro 22-6923 significantly inhibited food-stimulated aci...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01403843
更新日期:1985-04-01 00:00:00
abstract::The prevalence of the recently described deamidated gliadin peptide antibodies was compared with that of the routinely used antigliadin, antiendomysial, and tissue transglutaminase antibodies in the sera of 128 untreated celiac patients and 134 controls. Sensitivity and specificity for celiac disease were 83.6 and 90....
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-007-0058-0
更新日期:2008-06-01 00:00:00
abstract::Improvement of health-related quality of life (HRQOL) is a major determinant in decision-making for surgery in patients with Crohn's disease (CD). This study was designed to investigate the short- and long-term effect of surgical resection for CD on HRQOL. Sixteen patients were investigated within one week before surg...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1026600428484
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND:It is not known if genetic background, characteristics at diagnosis, physical and psychological well-being, and adherence to a gluten-free diet are comparable between patients with familial or sporadic celiac disease. These issues were investigated in a follow-up study. METHODS:Altogether 1064 patients were...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-020-06490-1
更新日期:2020-07-23 00:00:00
abstract::Telomerase acitivity can be induced in human B lymphocytes by in vitro stimulation of their antigen receptors. To determine whether telomerase activity is induced in vivo, we analyzed telomerase activity in B lymphocytes from the mesenteric lymph nodes of patients with inflammatory bowel disease (IBD), whose lymph nod...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1026107429546
更新日期:2003-10-01 00:00:00
abstract:BACKGROUND:Biliary cannulation failure is a major problem during endoscopic retrograde cholangiopancreatography. It remains unclear how duodenal papilla morphology affects biliary cannulation. Therefore, we proposed a new classification system for the duodenal papilla based on oral protrusion pattern (ratio of the leng...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章,多中心研究
doi:10.1007/s10620-019-05510-z
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:Hepatic encephalopathy (HE) is a serious neuropsychiatric complication in both acute and chronic liver disease. AIMS:To establish the utility of a portable noninvasive method to measure ammonia in the breath of healthy subjects and patients with HE. METHODS:The study included 106 subjects: 44 women and 62 ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-011-1858-9
更新日期:2012-01-01 00:00:00
abstract::Acid inhibition increases gastric mucosal susceptibility to damage by luminal acid. This might be due to reduced metabolic CO2 and bicarbonate whereas, during normal acid, secretion cytoprotective CO2/HCO3- production parallels acid production. Metabolic activity and mucosal damage caused by luminal acid perfusion was...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF02091538
更新日期:1996-05-01 00:00:00
abstract::In the period 1985-1988, 62 focal liver lesions in 58 cirrhotic patients were studied by ultrasonography; 12 of these focal lesions were documented to be regenerating lesions by echo-guided fine-needle biopsy. During an average follow-up period of 10.2 months (range 3-22 months), hepatocellular carcinoma was subsequen...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01536913
更新日期:1990-04-01 00:00:00
abstract::To study the efficacy and mechanism of action of the intragastric bubble, 1- to 5-ml silicone bubbles were surgically implanted into the stomachs of 10- to 12-week-old female rats. To test the hypothesis that the satiety effects of the implant are mediated by visceral sensory nerves, a subgroup was treated as neonates...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01300286
更新日期:1992-07-01 00:00:00
abstract::Background/Aims Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) as a newly identified biological agent has shown promising antitumor effects in a wide range of cancers. However, gastric cancer cells are less sensitive than other cancer cells to TRAIL-induced apoptosis.Here, we combined TRAIL with borte...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-010-1191-8
更新日期:2010-12-01 00:00:00
abstract::To test the role of immune reactivity in the pathogenesis of hepatitis C, serum soluble immune factors were measured in a cohort of 57 patients with chronic hepatitis C, and in 20 healthy subjects. Levels of interleukin-1 beta, granulocyte-macrophage colony-stimulating factor, tumor necrosis factor-alpha, and interleu...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF02087671
更新日期:1994-11-01 00:00:00
abstract::The results of 88 consecutive small-bowel enemas were compared retrospectively with the results of 52 routine small-bowel series and 50 barium enemas done in the same patients. Ninety-six percent of the diagnoses made by small-bowel enema were correct, as compared to only 65% made by routine small-bowel series. The in...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01391448
更新日期:1982-12-01 00:00:00
abstract:BACKGROUND:Data on ERCP nurses and associate (ERCP-NA) training and comfort are lacking. Healthcare industry representative (HCIR) influence may be greater in low-volume units (LVUs) due to decreased procedure and device familiarity. AIM:The aim of this study was to compare ERCP-NA training, safety, and HCIR relations...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-015-3926-z
更新日期:2016-03-01 00:00:00
abstract::The evaluation of suspected esophageal chest pain is frustrating because of difficulty in clearly implicating the esophagus. Balloon distention was considered as a new provocative test in the esophagus because it has been shown to safely produce pain in other hollow gastrointestinal organs. Studies were performed in 5...
journal_title:Digestive diseases and sciences
pub_type: 临床试验,杂志文章
doi:10.1007/BF01299805
更新日期:1986-12-01 00:00:00
abstract:BACKGROUND:The use of volatile organic compounds (VOCs) in bile was recently studied and appeared promising for diagnosis of malignancy. Noninvasive diagnosis of malignant biliary strictures by using VOCs in urine has not been studied. AIM:To identify potential VOCs in urine to diagnose malignant biliary strictures. ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-015-3596-x
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:A new device with metallic wires for scrape cytology was developed. AIMS:To compare the diagnostic performance of scrape cytology and conventional cytology during endoscopic retrograde cholangiopancreatography for biliary strictures. METHODS:A total of 420 cases with biliary stricture underwent transpapill...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-018-5217-y
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND AND AIMS:Accumulating evidence has indicated that variations of mitochondrial DNA (mtDNA) content may affect the susceptibility to hepatocellular carcinoma (HCC). However, no study has been conducted to evaluate the association of circulating mtDNA content and the risk of liver cirrhosis, a leading cause of ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-015-3523-1
更新日期:2015-06-01 00:00:00
abstract::Inhibitors of gastric acid secretion are efficient drugs in the treatment of acid-related diseases. However, by reducing gastric acidity, hypergastrinemia develops. Gastrin regulates its target cell, the enterochromaffin (ECL) cell, both functionally and tropicaly. Long-term hypergastrinemia in whatever species studie...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章,评审
doi:10.1007/s10620-005-2805-4
更新日期:2005-10-01 00:00:00
abstract::It is unknown whether demography, gallbladder function, or the radiographic appearance of gallstones predispose them to cause symptoms. We investigated these features in a consecutive series of 260 patients with newly diagnosed, uncomplicated gallstone disease, of whom 146 had experienced biliary pain and 114 were asy...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF02087779
更新日期:1994-08-01 00:00:00
abstract:BACKGROUND:Gastric acidification inhibits motilin-induced gastric phase III contractions. However, the underlying mechanism has not been thoroughly investigated. Here, we studied the inhibitory mechanism by gastric acidification on motilin-induced contraction in Suncus murinus (S. murinus). METHODS:We measured interdi...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-015-4023-z
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Inflammatory bowel disease (IBD) consists of ulcerative colitis (UC) and Crohn's disease (CD), which are complex genetic disorders resulting from the interplay between several genetic and environmental risk factors. The arylamine N-acetyltransferase 2 (NAT2) enzyme detoxifies a wide spectrum of n...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-010-1527-4
更新日期:2011-07-01 00:00:00
abstract::During topical dissolution of gallstones, solvent can escape to the duodenum causing toxic effects that have not yet been adequately quantified. We compared the local intestinal cytotoxic and systemic hepatotoxic effects of two gallstone solvents, methyl tert-butyl ether and ethyl propionate, on the rabbit's duodenum....
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1018830622508
更新日期:1997-03-01 00:00:00
abstract::We explored the hemodynamic effects of rapid injection of 0.9% saline and arterial blood into the canine superior mesenteric artery in anesthetized animals. Mesenteric artery blood flow and pressure were measured in the vessel distal to the site of injection. Injection rates were at or below the rate of blood flow in ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01309495
更新日期:1981-10-01 00:00:00
abstract::Inhibition of monoamine oxidase B (MAO B) by selective inhibitors pargyline and L-deprenyl increases dopamine (DA) and norepinephrine (NE) concentrations in nucleus accumbens (NACB) and is associated with reduction in cold water restraint-induced gastric mucosal injury, inhibition of basal gastric acid output, and reg...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01537224
更新日期:1990-01-01 00:00:00