Abstract:
:Improvement of health-related quality of life (HRQOL) is a major determinant in decision-making for surgery in patients with Crohn's disease (CD). This study was designed to investigate the short- and long-term effect of surgical resection for CD on HRQOL. Sixteen patients were investigated within one week before surgery and 3, 6, and 24 months postoperatively. Besides the Crohn's disease activity index (CDAI), four instruments: the time trade-off technique (TTO), the direct questioning of objectives (DQO), the rating form of inflammatory bowel disease patients concerns (RFIPC), and the Beck depression inventory--were used for assessment of HRQOL. CDAI decreased significantly after operation and 10 patients remained in remission for 24 months. Two patients had postoperative relapses and went into remission after prednisolone treatment. Four patients developed chronic active disease. HRQOL was significantly improved in all patients three and six months postoperatively. Except for the four patients with chronic active disease, all other patients (N = 12) had also significantly improved HRQOL after 24 months. In conclusion, surgical resections in CD lead to a long-term improvement of HRQOL with the exception of patients with chronic active disease. This finding might be taken in consideration for the indication of surgery in CD.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Tillinger W,Mittermaier C,Lochs H,Moser Gdoi
10.1023/a:1026600428484subject
Has Abstractpub_date
1999-05-01 00:00:00pages
932-8issue
5eissn
0163-2116issn
1573-2568journal_volume
44pub_type
杂志文章abstract::In the period 1985-1988, 62 focal liver lesions in 58 cirrhotic patients were studied by ultrasonography; 12 of these focal lesions were documented to be regenerating lesions by echo-guided fine-needle biopsy. During an average follow-up period of 10.2 months (range 3-22 months), hepatocellular carcinoma was subsequen...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01536913
更新日期:1990-04-01 00:00:00
abstract::To determine if organic anions contribute to the diarrhea of inflammatory bowel disease, we measured osmolality, electrolytes, short-chain fatty acids, lactic acid, and some Krebs cycle anions in 24-hr fecal collections from 18 patients with chronic ulcerative colitis, 20 with Crohn's disease of the colon, and 16 norm...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01536987
更新日期:1988-11-01 00:00:00
abstract::The purpose of this study was to characterize the diagnostic process, frequency of associated disorders, family history, and impact of a gluten-free diet in individuals with celiac disease. All members of the Canadian Celiac Association (n=5240) were surveyed with a questionnaire. Respondents included 2681 adults with...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-006-9258-2
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-019-05883-1
更新日期:2020-05-01 00:00:00
abstract::Minimal lesions of the small bowel are mucosal changes characterized by an increased number of intraepithelial lymphocytes (with or without crypt hyperplasia) and normal villous architecture. Such changes are associated with a wide spectrum of conditions, ranging from food intolerances to infections, and from drugs to...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章,评审
doi:10.1007/s10620-020-06571-1
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abstract::Our aims were to measure antral axial forces in patients with suspected upper gut dysmotilities and to compare the number of antral contractions detected by an axial force catheter and by manometric sensors in the distal antrum and pylorus. Fifteen patients (2 men, 13 women; mean age 42 years) underwent studies for 3 ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF02213125
更新日期:1996-04-01 00:00:00
abstract::Acute erosions of the stomach may occur in association with human spinal cord injuries. Erosion of the glandular portion of the stomach also occurs after cervical cord transection in the rat. Reports on the effects of antacids and cimetidine in the prevention of acute "stress" erosions in animals and humans have shown...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01296919
更新日期:1982-03-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-007-0184-8
更新日期:2008-10-01 00:00:00
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journal_title:Digestive diseases and sciences
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doi:10.1007/s10620-011-2026-y
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01536623
更新日期:1988-01-01 00:00:00
abstract::The aim of this study was to assess the efficacy of the combination of endoscopic variceal ligation (EVL) and partial splenic embolization (PSE) compared with EVL alone in cirrhosis patients with thrombocytopenia. In a prospective study, 84 cirrhosis patients with esophageal varices and thrombocytopenia (platelet coun...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章,随机对照试验
doi:10.1007/s10620-006-3137-8
更新日期:2006-02-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1018885217154
更新日期:1997-12-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章,评审
doi:10.1007/s10620-016-4109-2
更新日期:2016-07-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-005-9069-x
更新日期:2006-12-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-010-1344-9
更新日期:2011-03-01 00:00:00
abstract::We have investigated the presence, duration, and clinical significance of granulocyte accumulation, using indium-111 granulocyte scanning, in patients following uncomplicated intestinal anastomosis. Eight patients underwent intestinal resection and anastomosis (right hemicolectomy, 5; sigmoid colectomy, 2; ileal resec...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01318118
更新日期:1986-03-01 00:00:00
abstract::Local or national policy, patients' preferences, safety and/or economic concerns, or reimbursement issues may dictate stopping drug in inflammatory bowel diseases (IBD) patients. Sustained deep remission is an important predictor of a better outcome after anti-tumor necrosis (TNF) factor therapy discontinuation, inclu...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章,评审
doi:10.1007/s10620-015-3984-2
更新日期:2016-04-01 00:00:00
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journal_title:Digestive diseases and sciences
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doi:10.1023/a:1021778229997
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF02065520
更新日期:1995-06-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01540430
更新日期:1988-06-01 00:00:00
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journal_title:Digestive diseases and sciences
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更新日期:2002-03-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
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更新日期:1999-03-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-005-9003-2
更新日期:2006-05-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1018827613809
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01540043
更新日期:1989-11-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-010-1219-0
更新日期:2010-12-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01311944
更新日期:1979-12-01 00:00:00