Health-related quality of life in patients with Crohn's disease: influence of surgical operation--a prospective trial.

Abstract:

:Improvement of health-related quality of life (HRQOL) is a major determinant in decision-making for surgery in patients with Crohn's disease (CD). This study was designed to investigate the short- and long-term effect of surgical resection for CD on HRQOL. Sixteen patients were investigated within one week before surgery and 3, 6, and 24 months postoperatively. Besides the Crohn's disease activity index (CDAI), four instruments: the time trade-off technique (TTO), the direct questioning of objectives (DQO), the rating form of inflammatory bowel disease patients concerns (RFIPC), and the Beck depression inventory--were used for assessment of HRQOL. CDAI decreased significantly after operation and 10 patients remained in remission for 24 months. Two patients had postoperative relapses and went into remission after prednisolone treatment. Four patients developed chronic active disease. HRQOL was significantly improved in all patients three and six months postoperatively. Except for the four patients with chronic active disease, all other patients (N = 12) had also significantly improved HRQOL after 24 months. In conclusion, surgical resections in CD lead to a long-term improvement of HRQOL with the exception of patients with chronic active disease. This finding might be taken in consideration for the indication of surgery in CD.

journal_name

Dig Dis Sci

authors

Tillinger W,Mittermaier C,Lochs H,Moser G

doi

10.1023/a:1026600428484

subject

Has Abstract

pub_date

1999-05-01 00:00:00

pages

932-8

issue

5

eissn

0163-2116

issn

1573-2568

journal_volume

44

pub_type

杂志文章
  • Focal ultrasound lesions in liver cirrhosis diagnosed as regenerating nodules by fine-needle biopsy. Follow-up of 12 cases.

    abstract::In the period 1985-1988, 62 focal liver lesions in 58 cirrhotic patients were studied by ultrasonography; 12 of these focal lesions were documented to be regenerating lesions by echo-guided fine-needle biopsy. During an average follow-up period of 10.2 months (range 3-22 months), hepatocellular carcinoma was subsequen...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01536913

    authors: Rapaccini GL,Pompili M,Caturelli E,Anti M,Aliotta A,Cedrone A,Amadei E,Grattagliano A,Squillante MM,Rabitti C

    更新日期:1990-04-01 00:00:00

  • Organic anions and the diarrhea of inflammatory bowel disease.

    abstract::To determine if organic anions contribute to the diarrhea of inflammatory bowel disease, we measured osmolality, electrolytes, short-chain fatty acids, lactic acid, and some Krebs cycle anions in 24-hr fecal collections from 18 patients with chronic ulcerative colitis, 20 with Crohn's disease of the colon, and 16 norm...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01536987

    authors: Vernia P,Gnaedinger A,Hauck W,Breuer RI

    更新日期:1988-11-01 00:00:00

  • The Canadian Celiac Health Survey.

    abstract::The purpose of this study was to characterize the diagnostic process, frequency of associated disorders, family history, and impact of a gluten-free diet in individuals with celiac disease. All members of the Canadian Celiac Association (n=5240) were surveyed with a questionnaire. Respondents included 2681 adults with...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-006-9258-2

    authors: Cranney A,Zarkadas M,Graham ID,Butzner JD,Rashid M,Warren R,Molloy M,Case S,Burrows V,Switzer C

    更新日期:2007-04-01 00:00:00

  • Usefulness of Controlled Attenuation Parameter in Detecting and Monitoring Hepatic Steatosis with MRI-PDFF as Reference.

    abstract:BACKGROUND:Controlled attenuation parameter (CAP) has been developed to estimate the extent of hepatic steatosis. AIMS:The purpose was to evaluate the usefulness of CAP in assessing hepatic steatosis and its change using magnetic resonance imaging proton density fat fraction (MRI-PDFF) as reference standard. METHODS:...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-019-05883-1

    authors: Wang JH,Ou HY,Yen YH,Chen CH,Lu SN

    更新日期:2020-05-01 00:00:00

  • Minimal Lesions of the Small Intestinal Mucosa: More than Morphology.

    abstract::Minimal lesions of the small bowel are mucosal changes characterized by an increased number of intraepithelial lymphocytes (with or without crypt hyperplasia) and normal villous architecture. Such changes are associated with a wide spectrum of conditions, ranging from food intolerances to infections, and from drugs to...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,评审

    doi:10.1007/s10620-020-06571-1

    authors: Volta U,Caio G,Ghirardi C,Lungaro L,Mansueto P,Carroccio A,De Giorgio R

    更新日期:2020-10-01 00:00:00

  • Antral axial forces postprandially and after erythromycin in organic and functional dysmotilities.

    abstract::Our aims were to measure antral axial forces in patients with suspected upper gut dysmotilities and to compare the number of antral contractions detected by an axial force catheter and by manometric sensors in the distal antrum and pylorus. Fifteen patients (2 men, 13 women; mean age 42 years) underwent studies for 3 ...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF02213125

    authors: Surrenti E,Camilleri M,Kammer PP,Prather CM,Schei AJ,Hanson RB

    更新日期:1996-04-01 00:00:00

  • Effects of antacids, cimetidine, and 16,16-dimethyl prostaglandin E2 on acute gastric erosions in a spinal rat.

    abstract::Acute erosions of the stomach may occur in association with human spinal cord injuries. Erosion of the glandular portion of the stomach also occurs after cervical cord transection in the rat. Reports on the effects of antacids and cimetidine in the prevention of acute "stress" erosions in animals and humans have shown...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01296919

    authors: Sigman HH,Gillich A

    更新日期:1982-03-01 00:00:00

  • Lactulose/mannitol test and specificity, sensitivity, and area under curve of intestinal permeability parameters in patients with liver cirrhosis and Crohn's disease.

    abstract:UNLABELLED:The purpose of this study was to investigate and compare the specificity, sensitivity, and area under curve (AUC) of the lactulose/mannitol ratio, lactulose/creatinine ratio, and lactulose recovery and their diagnostic value for intestinal permeability assessment within the absorption lactulose/mannitol (L/M...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-007-0184-8

    authors: Dastych M,Dastych M Jr,Novotná H,Cíhalová J

    更新日期:2008-10-01 00:00:00

  • Combinatory RNA-Sequencing Analyses Reveal a Dual Mode of Gene Regulation by ADAR1 in Gastric Cancer.

    abstract:BACKGROUND:Adenosine deaminase acting on RNA 1 (ADAR1) is known to mediate deamination of adenosine-to-inosine through binding to double-stranded RNA, the phenomenon known as RNA editing. Currently, the function of ADAR1 in gastric cancer is unclear. AIMS:This study was aimed at investigating RNA editing-dependent and...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-018-5081-9

    authors: Cho CJ,Jung J,Jiang L,Lee EJ,Kim DS,Kim BS,Kim HS,Jung HY,Song HJ,Hwang SW,Park Y,Jung MK,Pack CG,Myung SJ,Chang S

    更新日期:2018-07-01 00:00:00

  • SEL1L, an UPR response protein, a potential marker of colonic cell transformation.

    abstract:BACKGROUND:SEL1L gene product is implicated in the endoplasmic reticulum (ER)-associated protein degradation and Unfolded Protein Response pathways. This gene and associated miRNAs have been indicated as predictive and prognostic markers of pancreatic cancer. AIM:Explore the role of SEL1L in colorectal cancer (CRC) pr...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-011-2026-y

    authors: Ashktorab H,Green W,Finzi G,Sessa F,Nouraie M,Lee EL,Morgano A,Moschetta A,Cattaneo M,Mariani-Costantini R,Brim H,Biunno I

    更新日期:2012-04-01 00:00:00

  • Gallbladder kinetics in obese patients. Effect of a regular meal and low-calorie meal.

    abstract::Gallbladder contractility has been studied in 21 obese patients (greater than 130% ideal weight) and 30 nonobese subjects before and at regular intervals after the administration of a regular solid-liquid meal, and after a low-calorie, low-fat meal used conventionally for weight-loss purposes (Modifast). Gallbladder v...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01536623

    authors: Marzio L,Capone F,Neri M,Mezzetti A,De Angelis C,Cuccurullo F

    更新日期:1988-01-01 00:00:00

  • Improved prognosis of cirrhosis patients with esophageal varices and thrombocytopenia treated by endoscopic variceal ligation plus partial splenic embolization.

    abstract::The aim of this study was to assess the efficacy of the combination of endoscopic variceal ligation (EVL) and partial splenic embolization (PSE) compared with EVL alone in cirrhosis patients with thrombocytopenia. In a prospective study, 84 cirrhosis patients with esophageal varices and thrombocytopenia (platelet coun...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s10620-006-3137-8

    authors: Ohmoto K,Yoshioka N,Tomiyama Y,Shibata N,Takesue M,Yoshida K,Kuboki M,Yamamoto S

    更新日期:2006-02-01 00:00:00

  • Nitrate-reducing bacteria in diversion colitis: a clue to inflammation?

    abstract::A pathogenic role of nitric oxide has been suggested in acute and chronic intestinal inflammation. We took the opportunity offered by studies in patients with excluded colon, which represents a model of chronic intestinal inflammation with no exogenous nitrite or nitrate supply, to evaluate the quantity and the qualit...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1018885217154

    authors: Neut C,Guillemot F,Colombel JF

    更新日期:1997-12-01 00:00:00

  • The Genetics of Barrett's Esophagus: A Familial and Population-Based Perspective.

    abstract::Barrett's esophagus (BE) is intestinal metaplasia of the lower esophagus and a precursor lesion for esophageal adenocarcinoma (EAC). Both are important health issues as they have rising incidences in the Western world. Improving the management of BE relies on understanding the underlying biology of this disease, but t...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,评审

    doi:10.1007/s10620-016-4109-2

    authors: To H,Clemons NJ,Duong CP,Trainer AH,Phillips WA

    更新日期:2016-07-01 00:00:00

  • Significance of endoscopy in asymptomatic premenopausal women with iron deficiency anemia.

    abstract::There is, currently, no consensus with regard to the role of endoscopy in the etiologic investigation of asymptomatic pemenopausal women suffering from iron deficiency anemia (IDA). We conducted a retrospective case-control study to evaluate the contribution of esophagogastroduodenoscopy (EGD) and colonoscopy to the e...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-005-9069-x

    authors: Park DI,Ryu SH,Oh SJ,Yoo TW,Kim HJ,Cho YK,Sung IK,Sohn CI,Jeon WK,Kim BI

    更新日期:2006-12-01 00:00:00

  • Experience with the new 4-way, 5.5-mm ultrathin endoscope: a case series.

    abstract:BACKGROUND AND STUDY AIMS:Use of ultrathin (ut) endoscopes is sometimes limited by their design (outer diameter, tip angulation and image quality). New ut-endoscopes are being designed to address these limitations. A new ut-endoscope, XGIF-PV70N5 (Olympus America Inc.), with an outer diameter of 5.5 mm, 4-way angulatio...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-010-1344-9

    authors: Agrawal D,Wong RC,Isenberg G,Faulx A,Chak A

    更新日期:2011-03-01 00:00:00

  • Granulocyte migration in uncomplicated intestinal anastomosis in man.

    abstract::We have investigated the presence, duration, and clinical significance of granulocyte accumulation, using indium-111 granulocyte scanning, in patients following uncomplicated intestinal anastomosis. Eight patients underwent intestinal resection and anastomosis (right hemicolectomy, 5; sigmoid colectomy, 2; ileal resec...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01318118

    authors: Keshavarzian A,Gibson R,Guest J,Spencer J,Lavender JP,Hodgson HJ

    更新日期:1986-03-01 00:00:00

  • Pharmacokinetics of Infliximab and Reduction of Treatment for Inflammatory Bowel Diseases.

    abstract::Local or national policy, patients' preferences, safety and/or economic concerns, or reimbursement issues may dictate stopping drug in inflammatory bowel diseases (IBD) patients. Sustained deep remission is an important predictor of a better outcome after anti-tumor necrosis (TNF) factor therapy discontinuation, inclu...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章,评审

    doi:10.1007/s10620-015-3984-2

    authors: Williet N,Paul S,Peyrin-Biroulet L,Roblin X

    更新日期:2016-04-01 00:00:00

  • A novel vitamin E derivative (TMG) protects against gastric mucosal damage induced by ischemia and reperfusion in rats.

    abstract::The aim of the present study was to investigate the antioxidative effects of water-soluble vitamin E derivative, 2-(alpha-D-glucopyranosyl)methyl-2,5,7,8-tetramethylchroman-6-ol (TMG), on ischemia-reperfusion (I/R) -induced gastric mucosal injury in rats. Gastric ischemia was induced by applying a small clamp to the c...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1021778229997

    authors: Ichikawa H,Yoshida N,Takano H,Ishikawa T,Handa O,Takagi T,Naito Y,Murase H,Yoshikawa T

    更新日期:2003-01-01 00:00:00

  • Hospital Cirrhosis Volume and Readmission in Patients with Cirrhosis in California.

    abstract:BACKGROUND:Patients with cirrhosis are at high readmission risk. Using a large statewide database, we evaluated the effect of hospital cirrhosis-related patient volume on 30-day readmissions in patients with cirrhosis. METHODS:We conducted a retrospective study of the Healthcare Cost and Utilization Project State Inpa...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-018-4964-0

    authors: Wei M,Ford J,Li Q,Jeong D,Kwong AJ,Nguyen MH,Chang MS

    更新日期:2018-09-01 00:00:00

  • Impact of microscopic duodenitis on symptomatic response to Helicobacter pylori eradication in functional dyspepsia.

    abstract:BACKGROUND AND AIM:There is no consensus regarding the benefit of eradicating Helicobacter pylori (H. pylori) infection in patients with functional dyspepsia (FD). We intended to compare the symptom response to H. pylori eradication in FD patients in presence or absence of microscopic duodenitis (MD). METHODS:Patients...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-014-3285-1

    authors: Mirbagheri SS,Mirbagheri SA,Nabavizadeh B,Entezari P,Ostovaneh MR,Hosseini SM,Rakhshani N,Safa H

    更新日期:2015-01-01 00:00:00

  • Correlation between biliary alpha 1-acid glycoprotein concentration and cholesterol crystal nucleation time in gallstone disease.

    abstract::A biliary form of the alpha 1-acid glycoprotein (AAG) promotes cholesterol crystallization in the lower-molecular-weight, concanavalin A-bound fraction of gallbladder bile. In addition, bile AAG concentration is higher in cholesterol gallstone patients with multiple stones than in control patients without gallstone di...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF02065520

    authors: Nuutinen H,Ginanni Corradini S,Jüngst D,Lange V,Abei M,Schwarzendrube J,Williams C,Holzbach RT

    更新日期:1995-06-01 00:00:00

  • Circulating IgA immune complexes and skin IgA deposits in liver disease. Relation to liver histopathology.

    abstract::Alcoholic liver disease (ALD) is characterized by elevated serum IgA concentrations, the presence of circulating immune complexes containing IgA, and IgA deposits along sinusoids in the liver. When combined with the presupposed IgA-clearance function of the liver, a causal association between IgA abnormalities and the...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01540430

    authors: van de Wiel A,Valentijn RM,Schuurman HJ,Daha MR,Hené RJ,Kater L

    更新日期:1988-06-01 00:00:00

  • Various S-GOT/S-GPT ratios in nonviral liver disorders and related physical conditions and life-style.

    abstract::The relationship between the GOT/GPT ratio in nonviral liver disorders and underlying physical condition and life-style were evaluated. The subjects were 12,808 male railway company workers who underwent an annual health checkup. Nonviral liver disorders were defined as elevated transaminases (GOT > 76 IU/liter or GPT...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1017959801493

    authors: Mukai M,Ozasa K,Hayashi K,Kawai K

    更新日期:2002-03-01 00:00:00

  • Plasma levels of matrix metalloproteinase-2 (MMP-2) and tissue inhibitors of metalloproteinases -1 and -2 (TIMP-1 and TIMP-2) as noninvasive markers of liver disease in chronic hepatitis C: comparison using ROC analysis.

    abstract::As chronic liver disease progresses, an imbalance occurs between synthesis and breakdown of extracellular matrix (ECM). Matrix metalloproteinases (MMPs) are involved in degrading ECM while tissue inhibitors of metalloproteinases (TIMPs) prevent their fibrolytic action. We determined if plasma levels of MMP-2, TIMP-1 a...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1026630129025

    authors: Walsh KM,Timms P,Campbell S,MacSween RN,Morris AJ

    更新日期:1999-03-01 00:00:00

  • Heat stress increases protein antigen transport across the intestinal epithelium via a mechanism of impairing proteolytic enzymatic activity.

    abstract::It has not been fully understood how intact protein antigens escape digestion in the course of absorption. The present study was designed to investigate the mechanism that heat stress induced an increase in intact protein antigen absorption. Human colonic cell line Caco-2 cells were treated with high temperature (37 t...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-005-9003-2

    authors: Yang PC,Wang CS

    更新日期:2006-05-01 00:00:00

  • Change in colonic motility after extrinsic autonomic denervation in dogs.

    abstract::Changes in colonic motility were compared in dogs undergoing autonomic denervation of the paraaortic and presacral (group A), paraaortic (group B), or mesocolonic region (group C), and sham operation (group D). Five bipolar recording electrodes were placed into the seromuscular layer of the colon and rectum. The numbe...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1023/a:1018827613809

    authors: Ishikawa M,Mibu R,Iwamoto T,Konomi H,Oohata Y,Tanaka M

    更新日期:1997-09-01 00:00:00

  • Campylobacter pylori is not associated with gastroparesis.

    abstract::There is a high incidence of Campylobacter pylori in the gastric mucosa of patients with duodenal ulcer, gastric ulcer, and nonulcer dyspepsia. Factors that lead to development of this infection are unknown. We hypothesized that delayed solid-phase gastric emptying, a condition characterized by antral stasis, might pr...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01540043

    authors: Barnett JL,Behler EM,Appelman HD,Elta GH

    更新日期:1989-11-01 00:00:00

  • Comparison of surrogate serum markers and transient elastography (Fibroscan) for assessing cirrhosis in patients with chronic viral hepatitis.

    abstract:BACKGROUND:Progressive hepatic fibrosis with development of cirrhosis is a feature of almost all chronic liver diseases. AIMS:We assessed the performance of Fibroscan in patients with chronic viral hepatitis, and in comparison with and combined with several surrogate serum markers for predicting cirrhosis. METHODS:In...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/s10620-010-1219-0

    authors: Lee MH,Cheong JY,Um SH,Seo YS,Kim DJ,Hwang SG,Yang JM,Han KH,Cho SW

    更新日期:2010-12-01 00:00:00

  • Acute right-sided hemorrhagic colitis associated with oral administration of ampicillin.

    abstract::Among 56 cases who presented to Kanto-Teishin Hospital complaining of bloody diarrhea or considerable hematochezia of acute onset, 8 cases (14.3%) were considered due to colitis associated with oral ampicillin therapy. The bloody diarrhea, often with abdominal cramps, began 2-7 days after starting the treatment. The d...

    journal_title:Digestive diseases and sciences

    pub_type: 杂志文章

    doi:10.1007/BF01311944

    authors: Sakurai Y,Tsuchiya H,Ikegami F,Funatomi T,Takasu S,Uchikoshi T

    更新日期:1979-12-01 00:00:00