Change in colonic motility after extrinsic autonomic denervation in dogs.

abstract：:In a subset of patients with gastroesophageal reflux disease (GERD), symptoms persist in spite of proton pump inhibitor (PPI) therapy. Endoscopic gastroplication (EG) was reported to provide a novel therapeutic option in GERD. To evaluate symptomatic and objective outcome of EG in PPI refractory GERD, consecutive GERD...

journal_title：Digestive diseases and sciences

authors： Arts J,Lerut T,Rutgeerts P,Sifrim D,Janssens J,Tack J

更新日期：2005-02-01 00:00:00

abstract：:Chronic abdominal wall pain (CAWP) is common and frequently mistaken for visceral pain. We determined the stability of this diagnosis with Main Outcome Measures of: (a) change of pain intensity after local anesthetic-corticosteroid injection, (b) pain relief after three or more months follow-up, and (c) costs of diagn...

journal_title：Digestive diseases and sciences

authors： Greenbaum DS,Greenbaum RB,Joseph JG,Natale JE

更新日期：1994-09-01 00:00:00

abstract：:While transilluminating guinea pig gastric wall, we noticed foci of irregular compression of submucosal veins and arteries, featuring parallel bands across arteries, with complete cessation of blood flow, mucosal pallor, and shrinkage of the area. Other features demonstrated that this was not due to artifactual pressu...

journal_title：Digestive diseases and sciences

authors： Piasecki CK,Thrasivoulou C

更新日期：1993-07-01 00:00:00

abstract：:A 65-year-old man with Crohn's disease died of acute myeloblastic leukemia after treatment for 11.8 years with 6-mercaptopurine, 1.5 mg/kg/day (100 mg/day). On cytogenetic analysis, most of the malignant bone marrow cells had deletion of chromosome 7, the most frequently reported cytogenetic abnormality in chemotherap...

journal_title：Digestive diseases and sciences

authors： Heizer WD,Peterson JL

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:Activation of the transcription factor NF-κB and expression of pro-inflammatory mediators have been considered as major events of acute pancreatitis (AP). Karyopherin alpha 2 (KPNA2), a member of the importin α family, reportedly modulates p65 subcellular localization. AIM:This study aimed to investigate th...

journal_title：Digestive diseases and sciences

authors： Cai Y,Shen Y,Gao L,Chen M,Xiao M,Huang Z,Zhang D

更新日期：2016-03-01 00:00:00

abstract：:Helicobacter pylori causes a lifelong infection in the stomach after exposure. H. pylorihas been shown to be associated with peptic ulcer and gastric cancer development. Moreover, it is held responsible for some other nongastric diseases. Among them, coronary heart disease attracts much debate. Many studies have demon...

journal_title：Digestive diseases and sciences

authors： Aydemir S,Bayraktaroglu T,Sert M,Sokmen C,Atmaca H,Mungan G,Gun BD,Borazan A,Ustundag Y

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Approximately 10-28 % of patients experience adverse drug reactions related to treatment with thiopurines. The most serious reaction is myelosuppression, typically manifested as leucopenia, which occurs in approximately 2-5 % of patients. Other adverse drug reactions that often accompany thiopurine therapy a...

journal_title：Digestive diseases and sciences

authors： Wroblova K,Kolorz M,Batovsky M,Zboril V,Suchankova J,Bartos M,Ulicny B,Pav I,Bartosova L

更新日期：2012-09-01 00:00:00

abstract：:A 68-year-old man developed hepatic injury with no hypersensitivity reaction after three years of hydralazine therapy. The liver injury histologically showed centrilobular zonal necrosis. Clinical, biochemical, and histological recovery followed discontinuation of the drug. Challenge tests and serial liver biopsies re...

journal_title：Digestive diseases and sciences

authors： Itoh S,Yamaba Y,Ichinoe A,Tsukada Y

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:We have reported previously that Candida albicans is involved in the pathogenesis of peptic ulcer perforation; it was shown that C. albicans aggravated the severity of duodenal ulceration and increased the rate of perforation. We considered it incumbent upon us to ascertain whether C. albicans is a virulence...

journal_title：Digestive diseases and sciences

authors： Nakamura T,Yoshida M,Kitagawa Y,Jin L,Ishikawa H,Kameyama K,Wakabayashi G,Tanabe M,Kawachi S,Shinoda M,Saikawa Y,Wada N,Kubota T,Kumai K,Sano K,Kitajima M

更新日期：2008-09-01 00:00:00

abstract：:Gastritis caused by Helicobacter pylori (HP) is common in patients with nonulcer dyspepsia (NUD), but an etiologic relationship between the histologic lesion and clinical symptoms is unproven. HP is inhibited by bismuth subsalicylate (BSS), a traditional remedy for dyspeptic complaints. The aim of this study was to as...

journal_title：Digestive diseases and sciences

authors： Marshall BJ,Valenzuela JE,McCallum RW,Dooley CP,Guerrant RL,Cohen H,Frierson HF Jr,Field LG,Jerdack GR,Mitra S

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Trinitrobenzenesulfonic acid (TNBS)-induced colitis is one of the most widely used experimental colitis models. However, there is no standard procedure for inducing colitis by TNBS because it is difficult to achieve a uniform distribution of colitis. We have developed a modified method of murine TNBS-induced...

journal_title：Digestive diseases and sciences

authors： Terai T,Osawa S,Tani S,Oishi S,Arai Y,Yamada T,Sugimoto M,Furuta T,Kanaoka S,Miyajima H,Sugimoto K

更新日期：2014-07-01 00:00:00

abstract：:Turmeric is widely used in Indian cuisine. The main constituents of turmeric are curcumin and its analogues, which are well-known antioxidant compounds. In the present study, we hypothesized that turmeric in curry might increase bowel motility and activate hydrogen-producing bacterial flora in the colon, thereby incre...

journal_title：Digestive diseases and sciences

authors： Shimouchi A,Nose K,Takaoka M,Hayashi H,Kondo T

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), which are most abundant in the liver, are the main enzymes involved in ethanol and acetaldehyde metabolism. AIMS:The purpose of this study was to compare the activity of ADH isoenzymes and ALDH between liver carcinoma cells and healthy hepatocyt...

journal_title：Digestive diseases and sciences

authors： Jelski W,Zalewski B,Szmitkowski M

更新日期：2008-09-01 00:00:00

abstract：:We measured suprahepatic vein and arterial partial oxygen pressure in 35 alcoholics with severe (N = 7) or mild (N = 28) histological liver damage and without evidence of clinical liver failure. The suprahepatic vein was punctured with a fine needle, using a percutaneous approach. Suprahepatic vein partial oxygen pres...

journal_title：Digestive diseases and sciences

authors： Bunout D,Moya P,de la Maza MP,Petermann M,Iturriaga H,Hirsch S

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Prior to the consensus guideline conference in 2007, eosinophilic esophagitis (EoE) was uncommon dominated by the fibrostenotic phenotype, but over the past decade has become a common cause of dysphagia with more inflammatory phenotypes diagnosed. We assessed the impact of guideline definitions on t...

journal_title：Digestive diseases and sciences

authors： Lipka S,Boyce HW,Kumar A,Richter JE

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Our previous study has shown that MYO5B is downregulated in gastric cancer. However, the mechanism by which the expression of MYO5B was inhibited remains unknown. METHODS:Inspection of the human MYO5B locus uncovered a large and dense CpG island within the 5' region of this gene. Methylation-specific PCR (M...

journal_title：Digestive diseases and sciences

authors： Dong W,Wang L,Shen R

更新日期：2013-07-01 00:00:00

abstract：INTRODUCTION:Assessment of whole gut transit, by radio-opaque markers or scintigraphy, is used to evaluate patients with constipation for slow gastrointestinal transit. Wireless capsule motility, using the SmartPill GI monitoring system, samples and transmits intraluminal pH, pressure, and temperature data from a capsu...

journal_title：Digestive diseases and sciences

authors： Maqbool S,Parkman HP,Friedenberg FK

更新日期：2009-10-01 00:00:00

abstract：:To investigate the pathophysiological basis of Courvoisier's law, the gallbladder size and pliability were measured in chronic calculous cholecystitis with (7 patients) or without (25 patients) common duct obstruction, in periampullary malignancy (6 patients), and in the normal state (3 patients). The duration and lev...

journal_title：Digestive diseases and sciences

authors： Chung RS

更新日期：1983-01-01 00:00:00

abstract：:The aim of this study was to assess the efficacy of the combination of endoscopic variceal ligation (EVL) and partial splenic embolization (PSE) compared with EVL alone in cirrhosis patients with thrombocytopenia. In a prospective study, 84 cirrhosis patients with esophageal varices and thrombocytopenia (platelet coun...

journal_title：Digestive diseases and sciences

authors： Ohmoto K,Yoshioka N,Tomiyama Y,Shibata N,Takesue M,Yoshida K,Kuboki M,Yamamoto S

更新日期：2006-02-01 00:00:00

abstract：:Models using dextran sulfate sodium (DSS) to induce experimental colitis in rodents have been performed mostly in adult animals. For this reason, we aimed to develop a model of colitis in young rats. DSS was administered to 30-day-old rats at concentrations ranging from 0.5 to 5% in drinking water. Young rats were rem...

journal_title：Digestive diseases and sciences

authors： Vicario M,Crespí M,Franch À,Amat C,Pelegrí C,Moretó M

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Eosinophilic esophagitis is among the causes of refractory reflux disease. Biopsy of esophagus is the gold standard for diagnosis. In this study we determined the frequency of eosinophilic esophagitis (EE) in refractory reflux cases referred to Motility Department of Shahid Beheshti Research Center of Gastro...

journal_title：Digestive diseases and sciences

authors： Foroutan M,Norouzi A,Molaei M,Mirbagheri SA,Irvani S,Sadeghi A,Derakhshan F,Tavassoli S,Besharat S,Zali M

更新日期：2010-01-01 00:00:00

abstract：:Eosinophilic gastroenteritis is a rare benign disease characterized by tissue eosinophilic infiltration that may involve several digestive tract layers. Also known as allergic, or eosinophilic allergic, gastroenteropathy, it usually involves the stomach and small intestine: rarely the colon. It may or may not be accom...

journal_title：Digestive diseases and sciences

authors： Méndez-Sánchez N,Chávez-Tapia NC,Vazquez-Elizondo G,Uribe M

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Tyrosine phosphorylation and dephosphorylation by protein tyrosine kinases and phosphatases (PTPs), respectively, play crucial roles in cellular signal transduction. Protein phosphatase non-receptor type 11 (PTPN11) is a positive signaling PTP that activates RAS and ERK signaling. Also, the PTPN11 binds with...

journal_title：Digestive diseases and sciences

authors： Kim JS,Shin OR,Kim HK,Cho YS,An CH,Lim KW,Kim SS

更新日期：2010-06-01 00:00:00

abstract：:Previous studies have demonstrated alterations in brain response to rectal distension in patients with irritable bowel syndrome (IBS) compared to controls. Our aim was to compare regional brain activity in response to rectal balloon distension in patients with IBS and healthy controls. We studied six patients with IBS...

journal_title：Digestive diseases and sciences

authors： Ringel Y,Drossman DA,Turkington TG,Bradshaw B,Hawk TC,Bangdiwala S,Coleman RE,Whitehead WE

更新日期：2003-09-01 00:00:00

abstract：:Animal studies have shown that calcium blocking drugs decrease lower esophageal sphincter pressure and inhibit peristaltic amplitude and duration. In a single-dose acute study, we compared the effects of a new oral calcium blocker, diltiazem (90, 120, 150 mg) with placebo in five volunteers and 10 patients with chest ...

journal_title：Digestive diseases and sciences

authors： Richter JE,Spurling TJ,Cordova CM,Castell DO

更新日期：1984-07-01 00:00:00

abstract：:We studied intraesophageal pressure changes in patients with symptoms of gastroesophageal reflux and an abnormal 24-hr pH monitoring record (N = 52). Our method was simultaneous esophageal manometry and pH monitoring. We observed a three-component esophageal manometric sequence (EMS). When this sequence recurred over ...

journal_title：Digestive diseases and sciences

authors： Shay SS,Eggli D,Oliver G,Peura DA,Johnson LF

更新日期：1989-09-01 00:00:00

abstract：:Patients with long-standing ulcerative colitis (UC) or Crohn's colitis are at increased risk of developing colorectal cancer (CRC). Given that most cases of CRC are thought to arise from dysplasia, previous guidelines have recommended endoscopic surveillance with random biopsies obtained from all segments of the colon...

journal_title：Digestive diseases and sciences

authors： Sengupta N,Yee E,Feuerstein JD

更新日期：2016-04-01 00:00:00

abstract：:In a young woman with Takayasu's arteritis, standard roentgenographic studies suggested a diagnosis of Crohn's ileocolitis. Mesenteric angiography was performed and revealed specific abnormalities diagnostic of Crohn's disease, namely, the zoning sign in the cecum with a hypervascular inner layer and a hypovascular ou...

journal_title：Digestive diseases and sciences

authors： Friedman CJ,Tegtmeyer CJ

更新日期：1979-12-01 00:00:00

abstract：:The original version of the article unfortunately contained tagging error in first and family name of authors Ariella Bar-Gil Shitrit and Ami Ben Ya'acov. This has been corrected with this erratum. ...

journal_title：Digestive diseases and sciences

authors： Bar-Gil Shitrit A,Cohen Y,Hassin O,Ben Ya'acov A,Farkash R,Koslowsky B,Milgrom Y,Livovsky DM,Samueloff A,Goldin E,Grisaru-Granovsky S

更新日期：2018-09-01 00:00:00

abstract：:We assessed the characteristics of muscarinic neural transmission in the vagal inhibitory pathway to the lower esophageal sphincter (LES) of anesthetized opossums. LES relaxation was induced by electrical stimulation of the cervical vagus. Measurements were made of LES relaxation before and after intravenous administr...

journal_title：Digestive diseases and sciences

authors： Gilbert RJ,Dodds WJ

更新日期：1987-10-01 00:00:00