Spasm of gastric muscularis mucosae might play a key role in causing focal mucosal ischemia and ulceration. An experimental study in guinea pigs.

abstract：BACKGROUND:Previous studies have shown vitamin D status to be associated with disease activity in patients with inflammatory bowel disease (IBD), but its influence on the clinical course of IBD has not been established. AIMS:We aimed to analyze whether the serum 25-hydroxyvitamin D3 [25(OH)D] status is associated with...

journal_title：Digestive diseases and sciences

authors： Ham NS,Hwang SW,Oh EH,Kim J,Lee HS,Park SH,Yang DH,Ye BD,Byeon JS,Myung SJ,Yang SK

更新日期：2020-03-26 00:00:00

abstract：:Consumption of high-fiber diets has been recommended prior to fecal blood testing to increase bleeding from polyps, cancer, and other lesions associated with mucosal erosion in the gastrointestinal tract. The effect of a high-fiber diet on fecal hemoglobin loss was examined in 17 healthy subjects during two dietary pe...

journal_title：Digestive diseases and sciences

authors： Slavin JL,Melcher EA,Sundeen M,Schwartz S

更新日期：1991-07-01 00:00:00

abstract：:A method for isolating and characterizing intestinal lymphoid cells from colonoscopic biopsies is presented. Intraepithelial lymphocytes were separated from the lamina propria by incubation in edetic acid (EDTA) and lamina propria lymphoid cells isolated by incubation in collagenase followed by Ficoll-Hypaque density ...

journal_title：Digestive diseases and sciences

authors： Comer GM,Ramey WG,Kotler DP,Holt PR

更新日期：1986-02-01 00:00:00

abstract：:Using conventional statistical analysis and multiple regression analysis, we investigated the viral and host factors that influence the response to recombinant interferon-alpha 2a therapy in patients with chronic hepatitis C. A total of 36 patients was randomly assigned to three administration schedules, 12 patients i...

journal_title：Digestive diseases and sciences

authors： Matsumoto A,Tanaka E,Suzuki T,Ogata H,Kiyosawa K

更新日期：1994-06-01 00:00:00

abstract：:Although viral hepatitis infection is known to be associated with aplastic anemia, a causal link between viral hepatitis and aplastic anemia has not been convincingly demonstrated. A case of hepatitis B-associated severe aplastic anemia is described which only partially responded to conventional immunosuppressive trea...

journal_title：Digestive diseases and sciences

authors： Bozkaya H,Yurdaydin C,Törüner M,Arat M,Bozdayi AM,Erekul S,Cinar K,Koç H,Uzunalimoğlu O

更新日期：2002-08-01 00:00:00

abstract：:Orlistat (tetrahydrolipstatin) is a potent inhibitor of gastric and pancreatic lipase activity causing a diminution of free fatty acids in the intestinal lumen. The release of cholecystokinin (CCK) critically depends on the presence of free fatty acids in the small intestine. Postprandial CCK release and gallbladder c...

journal_title：Digestive diseases and sciences

authors： Froehlich F,Hartmann D,Guezelhan C,Gonvers JJ,Jansen JB,Fried M

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Diverticulosis, a prevalent condition at screening colonoscopy, has been associated with colorectal cancers that develop after a clearing colonoscopy, or interval cancers. AIMS:To quantify the overall risk of diverticulosis in the development of interval cancers and examine this association in relevant subg...

journal_title：Digestive diseases and sciences

authors： Cooper GS,Xu F,Schluchter MD,Koroukian SM,Barnholtz Sloan JS

更新日期：2014-11-01 00:00:00

abstract：:The effect on the mucosa of sodium nitrite that enters the colon from the ileum or transmucosally from the circulation is unknown. Isolated colonic mucosal cells and Roux-en-Y colostomies were used to test whether high doses of sodium nitrite (5-40 mM) had any harmful histological or inhibitory metabolic actions on th...

journal_title：Digestive diseases and sciences

authors： Roediger WE,Radcliffe BC,Deakin EJ,Nance SH

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND AND AIM:Aberrant methylation of specific genes is frequent event in hepatocellular carcinoma (HCC). Our present study aims to explore the methylation levels of acid phosphatase locus 1 (ACP1), bone morphogenetic protein 4 (BMP4), and testis-specific protein, Y-encoded-like 5 (TSPYL5) and their potential clin...

journal_title：Digestive diseases and sciences

authors： Qiu X,Hu B,Huang Y,Deng Y,Wang X,Zheng F

更新日期：2016-01-01 00:00:00

abstract：:This study was designed to evaluate the role of 111In-labeled leukocyte imaging and fecal excretion in the assessment of inflammatory bowel disease. We compared these tests to various indices of disease activity in Crohn's disease, to Truelove's grading in ulcerative colitis, and to endoscopy, x-ray, and pathology in ...

journal_title：Digestive diseases and sciences

authors： Leddin DJ,Paterson WG,DaCosta LR,Dinda PK,Depew WT,Markotich J,McKaigney JP,Groll A,Beck IT

更新日期：1987-04-01 00:00:00

abstract：:The pathophysiology of constipation after rectopexy remains unclear: acquired anorectal dysfunction or preoperative colonic state are, by turns, the supposed culprit. The aim of this prospective study was to characterize the colorectal motility abnormalities encountered after such a surgical procedure. Twelve patients...

journal_title：Digestive diseases and sciences

authors： Siproudhis L,Ropert A,Gosselin A,Bretagne JF,Heresbach D,Raoul JL,Gosselin M

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Intestinal failure is the most critical complication of Crohn's disease. Intestinal failure requires home parenteral nutrition, which worsens the quality of life of the patients and sometimes causes life-threatening complications. AIMS:The purpose of this study was to investigate the incidence and risk fact...

journal_title：Digestive diseases and sciences

authors： Watanabe Y,Miyoshi N,Fujino S,Takahashi H,Haraguchi N,Hata T,Matsuda C,Yamamoto H,Doki Y,Mori M,Mizushima T

更新日期：2019-08-01 00:00:00

abstract：:The effect of nutrients on small intestinal motility is controversial. Our aim was to analyze the effect of intraduodenal infusion of mixtures of nutrients of increasing caloric load, on intestinal motility. Studies were performed in dogs with a duodenal cannula. Isosmolar infusions of saline, 0.5, 2, and 4 kcal/min w...

journal_title：Digestive diseases and sciences

authors： Defilippi C

更新日期：2003-08-01 00:00:00

abstract：:We examined the preventive effect of metoclopramide on the development of esophageal varices in a rat model. Thirty rats were divided into three groups: metoclopramide (7.5 mg/kg twice a day, intraperitoneally), control group I (saline 2 ml/kg twice a day, intraperitoneally), and control group II (incised lower esopha...

journal_title：Digestive diseases and sciences

authors： Ohta M,Hashizume M,Tanoue K,Ueno K,Komori K,Ishii T,Kitano S,Sugimachi K

更新日期：1994-09-01 00:00:00

abstract：:Selected aspects of bile acid metabolism were assessed in six women with primary biliary cirrhosis and varying degrees of cholestasis. Urinary bile acid excretion was markedly increased and correlated highly with serum levels. In three patients in whom urinary bile acids were separated by chromatography, the majority ...

journal_title：Digestive diseases and sciences

authors： Raedsch R,Lauterburg BH,Hofmann AF

更新日期：1981-05-01 00:00:00

abstract：BACKGROUND:HAb18G/CD147 expression has been associated with many tumor invasion molecules, which play important roles in recurrence and poor differentiation of esophageal squamous cell carcinoma (ESCC). However, the clinical implications of HAb18G/CD147 in ESCC are still unclear. AIMS:In this study, we clarified the c...

journal_title：Digestive diseases and sciences

authors： Zhu S,Li Y,Mi L,Zhang Y,Zhang L,Gong L,Han X,Yao L,Lan M,Chen Z,Zhang W

更新日期：2011-12-01 00:00:00

abstract：:Vitamin D deficiency is frequently observed in patients with Crohn's disease and may be associated with an increased risk of development of metabolic bone disease. To estimate the incidence of metabolic bone disease by noninvasive methods, 31 patients (17-75 years old) with Crohn's disease and low 25-hydroxyvitamin D ...

journal_title：Digestive diseases and sciences

authors： Vogelsang H,Ferenci P,Woloszczuk W,Resch H,Herold C,Frotz S,Gangl A

更新日期：1989-07-01 00:00:00

abstract：OBJECTIVES:The aim of the present study was to determine the potential for pancreatic calcification in autoimmune pancreatitis by investigating osteopontin and CD44 expression. METHODS:Human pancreatic tissues in normal pancreas, chronic pancreatitis, and autoimmune pancreatitis were obtained from the surgical specime...

journal_title：Digestive diseases and sciences

authors： Takada H,Nakazawa T,Ohara H,Ando T,Hayashi K,Naito I,Okumura F,Tanaka H,Yamada T,Takahashi S,Joh T

更新日期：2009-04-01 00:00:00

abstract：:Calcitonin gene-related peptide (CGRP) is thought to be involved in the regulation of gastric and mesenteric blood flow, in the control of gastric acid secretion and in the modulation of intestinal motility, yet the precise physiological roles of CGRP remain to be elucidated. To further examine the role(s) of CGRP in ...

journal_title：Digestive diseases and sciences

authors： Thompson BJ,Washington MK,Kurre U,Singh M,Rula EY,Emeson RB

更新日期：2008-01-01 00:00:00

abstract：:In cases of difficult biliary cannulation, transpancreatic sphincterotomy (TPS) can be an alternative approach of biliary access. However, its success and safety profile have not been studied in detail. A systematic review and meta-analysis were performed to study the overall cannulation success and adverse events of ...

journal_title：Digestive diseases and sciences

authors： Pécsi D,Farkas N,Hegyi P,Varjú P,Szakács Z,Fábián A,Varga G,Rakonczay Z Jr,Bálint ER,Erőss B,Czimmer J,Szepes Z,Vincze Á

更新日期：2019-09-01 00:00:00

abstract：:Apoptosis is an important process in a wide variety of different biological systems. In addition to caspases, recently, calpains, another family of proteases, have been found to be involved in apoptosis of many cell systems. This study is designed with the aims to evaluate the possible effect of Z-LLY-FMK (a calpain i...

journal_title：Digestive diseases and sciences

authors： Sheen-Chen SM,Ho HT,Eng HL

更新日期：2009-11-01 00:00:00

abstract：:A 24-year-old white woman presented with abdominal discomfort associated with a firm, nonpulsatile hepatic mass. Radiological examination, which included radionuclide liver scan, abdominal ultrasonography, computed tomography, and hepatic angiography, demonstrated a large, globular, multilocular cyst arising from the ...

journal_title：Digestive diseases and sciences

authors： Marcial MA,Hauser SC,Cibas ES,Braver J

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:Diarrhea, a major pathological hallmark of inflammatory bowel disease, is characterized by a significant reduction in the expression and function of key intestinal ion transporters. The adoptive naïve CD4+ T cell transfer colitis is an immune-based, chronic colitis mouse model which resembles human Crohn's d...

journal_title：Digestive diseases and sciences

authors： Jayawardena D,Tyagi S,Nazmi A,Olivares-Villagómez D,Dudeja PK

更新日期：2020-06-01 00:00:00

abstract：:To investigate the colonic adenoma-adenocarcinoma progression sequence, DNA ploidy analysis was performed on hyperplastic polyps to adenocarcinomas. DNA ploidy data were then compared with immunocytochemical staining for proliferating cell nuclear antigen (PCNA). In hyperplastic polyps to villous adenomas, all cases w...

journal_title：Digestive diseases and sciences

authors： Tomita T

更新日期：1995-05-01 00:00:00

abstract：:We have developed an improved semiconductor recording probe for monitoring motility of the upper small intestine in humans. The probe consists of six ultraminiature silicon pressure sensors spaced 10 cm apart and encased in a flexible polyurethane sheath. The probe is small [2.67 mm (8F) diameter], is easily passed tr...

journal_title：Digestive diseases and sciences

authors： Mathias JR,Sninsky CA,Millar HD,Clench MH,Davis RH

更新日期：1985-02-01 00:00:00

abstract：:Clinical features and liver biopsy findings were studied in six patients with nonalcoholic steatohepatitis associated with hyalin. A comparative study was made on the ultrastructure of the hyalin in one patient with nonalcoholic steatohepatitis and in one patient with alcoholic hepatitis. The patients, all over 50 yea...

journal_title：Digestive diseases and sciences

authors： Itoh S,Matsuo S,Ichinoe A,Yamaba Y,Miyazawa M

更新日期：1982-04-01 00:00:00

abstract：BACKGROUND:The high mobility group protein A2 (HMGA2) is an architectural transcription factor that plays an important role in the development and progression of many malignant neoplasms. High expression of HMGA2 in gastric cancer correlates with invasiveness of cancer and is an independent prognostic factor. The reaso...

journal_title：Digestive diseases and sciences

authors： Zha L,Zhang J,Tang W,Zhang N,He M,Guo Y,Wang Z

更新日期：2013-03-01 00:00:00

abstract：:Our purpose was to evaluate the relationship between the clinical and histological features in a cohort of patients who had gastroesophageal reflux-related lesions diagnosed after upper digestive endoscopy. In all, 589 patients scheduled for elective endoscopy in a multicentric prospective study were evaluated. Multip...

journal_title：Digestive diseases and sciences

authors： Aste H,Bonelli L,Ferraris R,Conio M,Lapertosa G

更新日期：1999-12-01 00:00:00

abstract：:The effect of inhibition of acid secretion on parietal cell morphology and the concentration of H,K-ATPase alpha-subunit protein was determined by electron microscopy and western blotting. Omeprazole or famotidine alone or in combination were used. Control animals showed a morphological stimulation index (0 = resting,...

journal_title：Digestive diseases and sciences

authors： Scott DR,Besancon M,Sachs G,Helander H

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Repeated challenges of lipopolysaccharide (LPS) could reduce the expression of proinflammatory cytokines in vitro, and oral administration of ovalbumin (OVA) induces mucosal tolerance in vivo. However, the effect of local administration of LPS and OVA on experimental colitis in vivo remains unknown. AIMS:Th...

journal_title：Digestive diseases and sciences

authors： Im JP,Ye BD,Kim JM,Jung HC,Song IS,Kim JS

更新日期：2011-08-01 00:00:00