Eosinophilic esophagitis in patients with refractory gastroesophageal reflux disease.

abstract：:Isosmotic liquid peptone meals adjusted to pH 7, 3, and 1.5 were instilled on separate days into the stomachs of 8 duodenal ulcer patients and 7 healthy controls. Using a marker-dilution method, duodenal acid load (DAL) was measured as the amount of unbuffered hydrogen ions delivered to the duodenum per unit time. Gas...

journal_title：Digestive diseases and sciences

authors： Lam SK,Isenberg JI,Grossman MI,Lane WH,Hogan DL

更新日期：1982-07-01 00:00:00

abstract：:Patients with persistently normal ALT affected with HCV-related chronic hepatitis exist. The natural history of liver disease in these patients was demonstrated to be very slow and progression to cirrhosis likely absent. The case we report describes the occurrence of hepatocellular carcinoma (HCC) in a patient with pe...

journal_title：Digestive diseases and sciences

authors： Persico M,Palmentieri B,Coppola L,Di Giacomo Russo G,De Marino F,De Sio I,Torella R

更新日期：2002-11-01 00:00:00

abstract：:Obesity and diet affect the incidence and severity of various types of cancer, including colon cancer. It is not known whether obesity, independent of diet, is a risk factor for colon adenocarcinoma. We used azoxymethane (AOM) to induce colon cancer in mature genetically obese male Zucker rats (fa/fa) on low-fat crude...

journal_title：Digestive diseases and sciences

authors： Weber RV,Stein DE,Scholes J,Kral JG

更新日期：2000-05-01 00:00:00

abstract：:Following surgical operations, opiate analgesics are widely used to control pain. This situation was used to investigate patterns of human gastroduodenal motility and the effect of opiate analgesics on this motility during the early postoperative period. Gastric contractions were absent for 6--12 hr following surgery ...

journal_title：Digestive diseases and sciences

authors： Ingram DM,Catchpole BN

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:Obesity is considered a risk factor for other chronic diseases, and diets rich in lipids can cause alterations in the intestinal functions. AIM:The aim of this study was to investigate the effects of a high-fat diet (HFD) on the myenteric plexus of the large intestine in mice. METHODS:Swiss mice were distr...

journal_title：Digestive diseases and sciences

authors： Beraldi EJ,Soares A,Borges SC,de Souza AC,Natali MR,Bazotte RB,Buttow NC

更新日期：2015-04-01 00:00:00

abstract：:Hepatolithiasis is a major disease in Asia but differences in operative incidence between countries have not been examined. A retrospective study was conducted in Taiwan, Hong Kong, and Singapore, and the results were compared with those in Japan with the aim of defining factors involved in the etiology of the conditi...

journal_title：Digestive diseases and sciences

authors： Nakayama F,Soloway RD,Nakama T,Miyazaki K,Ichimiya H,Sheen PC,Ker CG,Ong GB,Choi TK,Boey J

更新日期：1986-01-01 00:00:00

abstract：:Our aim was to compare standard liver function tests (serum bilirubin, serum albumin and prothrombin concentration), with lidocaine and monoethylglycinexylidide pharmacokinetic parameters, after oral lidocaine administration, to assess hepatic function of cirrhotic individuals. Twenty-one consecutive cirrhotic patient...

journal_title：Digestive diseases and sciences

authors： Muñoz AE,Miguez C,Rubio M,Bartellini M,Levi D,Podestá A,Niselman V,Terg R

更新日期：1999-04-01 00:00:00

abstract：:Patients with previous gastric surgery for benign conditions are thought to be at increased risk for gastric cancer based on studies from Europe. Recommendations have been made to screen these patients repeatedly in order to detect early gastric cancers. We conducted a case-control study to estimate the risk in the Un...

journal_title：Digestive diseases and sciences

authors： Sandler RS,Johnson MD,Holland KL

更新日期：1984-08-01 00:00:00

abstract：:Verapamil, a type-1 calcium-channel blocker, given intraperitoneally, macroscopically protected the gastric mucosa of rats from 96% ethanol-induced lesions in a dose-dependent fashion. This effect was significant when verapamil at 10 or 20 mg/kg was given 1 hr before ethanol. Histopathologically, verapamil prevented t...

journal_title：Digestive diseases and sciences

authors： Gutiérrez-Cabano CA

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:While the short-term benefits of exclusive enteral nutrition (EEN) for induction of remission in children with Crohn's disease (CD) are well documented, the longer-term outcomes are less clear. AIM:This retrospective study aimed to ascertain the outcomes for up to 24 months following EEN in a group of child...

journal_title：Digestive diseases and sciences

authors： Lambert B,Lemberg DA,Leach ST,Day AS

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:There are sporadic reports in the literature in which radiologic liver and lung lesions found incidentally during follow-up metastatic surveillance were shown to be caused by toxocariasis. AIMS:The objective of the work discussed in this report was to identify common clinical and histopathological features ...

journal_title：Digestive diseases and sciences

authors： Park S,Kim YS,Kim YJ,Kyung SY,Park JW,Jeong SH,Lee SP

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Microinflammation frequently develops in chronic uremia with pathological intestinal changes. However, the relationship between gut bacterial translocation and microinflammation in uremia has not been widely investigated. AIM:This study aimed to investigate whether gut microbiome dysbiosis and translocation...

journal_title：Digestive diseases and sciences

authors： Wang F,Zhang P,Jiang H,Cheng S

更新日期：2012-11-01 00:00:00

abstract：:Polycystic liver disease (PCLD) without polycystic kidney is infrequent in clinical setting. Family clustering is found in patients with PCLD, and it is inherited in an autosomal dominant fashion. Through positional cloning in North America and Europe (mostly in Dutch and Finnish descents), mutations in PRKCSH gene on...

journal_title：Digestive diseases and sciences

authors： Yang AM,Shih SC,Chu CH,Wang TE,Yang WS

更新日期：2010-03-01 00:00:00

abstract：:Modern methods of diagnosing diarrhea-predominant irritable bowel syndrome (D-IBS) require a "diagnosis of exclusion" approach. In this study we aim to test the diagnostic ability of using the fluctuation of frequency and consistency of bowel patterns in IBS to discriminate it from other causes of diarrhea. Eligible s...

journal_title：Digestive diseases and sciences

authors： Pimentel M,Hwang L,Melmed GY,Low K,Vasiliauskas E,Ippoliti A,Yang J,Lezcano S,Conklin JL,Sahakian A

更新日期：2010-01-01 00:00:00

abstract：:Crohn's disease (CD) is a heterogeneous disorder. A genetic linkage to chromosome 16 (IBD1) has been previously observed and replicated in unrelated populations. Recently, in this region, NOD2/CARD15 has been identified as a susceptibility gene. The aim of this report is to determine whether this gene is implicated in...

journal_title：Digestive diseases and sciences

authors： Zouiten-Mekki L,Zaouali H,Boubaker J,Karoui S,Fekih M,Matri S,Hamzaoui S,Filali A,Chaabouni H,Hugot JP

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Cognitive deficiency noted post-liver transplantation might be a result of consequential metabolic derangement before liver transplantation. Long-chain polyunsaturated fatty acids, especially arachidonic acid (AA) and docosahexaenoic acid (DHA), affect the development of the central nervous system and its ab...

journal_title：Digestive diseases and sciences

authors： Chen CC,Huang LT,Tain YL,Chaung HC,Hsieh CS,Eng HL,Wei YC,Yang CY

更新日期：2010-10-01 00:00:00

abstract：:Maintenance of intragastric pH > 4 is vital for effective management of gastroesophageal reflux disease (GERD). Esomeprazole 40 mg, the first proton pump inhibitor developed as an optical isomer, demonstrates improved acid inhibition over omeprazole 20 mg. Our aim was to compare esomeprazole 40 mg with omeprazole 40 m...

journal_title：Digestive diseases and sciences

authors： Röhss K,Hasselgren G,Hedenström H

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND:The chemokine SDF-1 and its receptor CXCR4 are essential for the proper functioning of multiple organs. In the liver, cholangiocytes and hepatic progenitor cells (HPCs) are the main cells that produce SDF-1, and SDF-1 is thought to be essential for HPC-stimulated liver regeneration. AIMS:In this study, CXCR...

journal_title：Digestive diseases and sciences

authors： Tsuchiya A,Imai M,Kamimura H,Takamura M,Yamagiwa S,Sugiyama T,Nomoto M,Heike T,Nagasawa T,Nakahata T,Aoyagi Y

更新日期：2012-11-01 00:00:00

abstract：:To investigate a potential new treatment for gastric Helicobacter pylori infection, we have examined the use of the natural antibiotic lactoferrin, found in bovine milk, for activity against Helicobacter species both in vitro and in vivo. Lactoferrin was bacteriostatic to H. pylori when cultured at concentrations > or...

journal_title：Digestive diseases and sciences

authors： Dial EJ,Hall LR,Serna H,Romero JJ,Fox JG,Lichtenberger LM

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Accumulating evidence has indicated that variations of mitochondrial DNA (mtDNA) content may affect the susceptibility to hepatocellular carcinoma (HCC). However, no study has been conducted to evaluate the association of circulating mtDNA content and the risk of liver cirrhosis, a leading cause of ...

journal_title：Digestive diseases and sciences

authors： Wang C,Hann HW,Hann RS,Wan S,Myers RE,Ye Z,Xing J,Yang H

更新日期：2015-06-01 00:00:00

abstract：:A primary histiocytic lymphoma arising in the esophagus and its resultant spontaneous perforation is reported in a 69-year-old female. To our knowledge esophageal perforation occurring as a complication of a primary non-Hodgkin's lymphoma of the esophagus has not been previously reported. ...

journal_title：Digestive diseases and sciences

authors： Kirsch HL,Cronin DW,Stein GN,Latour F,Herrera AF

更新日期：1983-04-01 00:00:00

abstract：:Growing evidence suggests that complex gene and environment interactions underlie a number of diseases including chronic inflammatory diseases of the digestive system. The rapid advances in information and technology provide opportunities to discover the risks or etiology for a variety of disorders within individual p...

journal_title：Digestive diseases and sciences

authors： Whitcomb DC,Aoun E,Vodovotz Y,Clermont G,Barmada MM

更新日期：2005-12-01 00:00:00

abstract：:A newly developed enzymatic method for determining urinary 3 alpha-sulfated bile acids was used to measure serum 3 alpha-sulfated bile acid levels in 114 patients with hepatobiliary diseases and 56 healthy subjects. The lowest measurable amount of the 3 alpha-sulfated bile acids was 0.5 mumol/liter. The standard curve...

journal_title：Digestive diseases and sciences

authors： Kato T,Yoneda M,Nakamura K,Makino I

更新日期：1996-08-01 00:00:00

abstract：INTRODUCTION:Scant data exist about accidental occupational injuries in endoscopy suites. This work systematically analyzes injuries, identifies workplace hazards, and proposes hazard remediation to potentially reduce risks. METHODS:A retrospective study was performed on 14 previously unreported injuries among 120 end...

journal_title：Digestive diseases and sciences

authors： Cappell MS

更新日期：2011-02-01 00:00:00

abstract：:The gastric acid response to a 200-ml cup of tea was measured by in situ titration in 36 patients with duodenal ulcer (DU) and 56 without duodenal ulcer (controls). Tea resulted in an acid secretory response which was almost equal to that after a maximal dose (0.04 mg/kg) of histamine. The effect of tea was mainly due...

journal_title：Digestive diseases and sciences

authors： Dubey P,Sundram KR,Nundy S

更新日期：1984-03-01 00:00:00

abstract：:The evaluation of agents potentially accelerating gastric emptying in gastric stasis syndromes is time-consuming. Since a previous study showed that emptying is slowed after antecedent fat ingestion and intravenous cisapride abolishes this effect, we investigated whether emptying delayed by fat incorporated into a mea...

journal_title：Digestive diseases and sciences

authors： Stacher G,Granser GV,Bergmann H,Kugi A,Stacher-Janotta G,Höbart J

更新日期：1991-09-01 00:00:00

abstract：:The literature regarding the effect of nicotine and cigarette smoke on gastric blood flow is conflicting. The hydrogen gas clearance technique was used to measure the effects of nicotine and cigarette smoke on basal gastric mucosal blood flow in anesthetized rats. Blood flow was measured before, during, and after trea...

journal_title：Digestive diseases and sciences

authors： Robert ME,Leung FW,Guth PH

更新日期：1986-05-01 00:00:00

abstract：:Concentration and voltage dependence of Mg transport across the rat duodenum was measured in an Ussing chamber. Mucosa (m) to serosa (s) Mg flux exhibits a cellular fraction comparable to that found for Ca. Mg sm flux is purely diffusive and probably restricted to the paracellular pathway. At all concentrations betwee...

journal_title：Digestive diseases and sciences

authors： Karbach U,Schmitt A,Saner FH

更新日期：1991-11-01 00:00:00

abstract：:Animal studies have shown that calcium blocking drugs decrease lower esophageal sphincter pressure and inhibit peristaltic amplitude and duration. In a single-dose acute study, we compared the effects of a new oral calcium blocker, diltiazem (90, 120, 150 mg) with placebo in five volunteers and 10 patients with chest ...

journal_title：Digestive diseases and sciences

authors： Richter JE,Spurling TJ,Cordova CM,Castell DO

更新日期：1984-07-01 00:00:00

abstract：:We have previously shown that methane on lactulose breath test (LBT) is highly associated with constipation in IBS and that methane gas itself slows small bowel transit in dogs. Previous studies suggest that serotonin may have a role in the control of transit in IBS. In this study, we aim to evaluate the role of serot...

journal_title：Digestive diseases and sciences

authors： Pimentel M,Kong Y,Park S

更新日期：2004-01-01 00:00:00