Accidental occupational injuries to endoscopy personnel in a high-volume endoscopy suite during the last decade: mechanisms, workplace hazards, and proposed remediation.

abstract：:Clinical features and liver biopsy findings were studied in six patients with nonalcoholic steatohepatitis associated with hyalin. A comparative study was made on the ultrastructure of the hyalin in one patient with nonalcoholic steatohepatitis and in one patient with alcoholic hepatitis. The patients, all over 50 yea...

journal_title：Digestive diseases and sciences

authors： Itoh S,Matsuo S,Ichinoe A,Yamaba Y,Miyazawa M

更新日期：1982-04-01 00:00:00

abstract：BACKGROUND:Regenerating islet-derived 3 (Reg3) is abnormally expressed in several human digestive system diseases, including chronic pancreatitis (CP) and pancreatic cancer (PC). AIM:The purpose of this study was to clarify the mechanism of the enhanced expression of Reg3 in inflammation-induced PC. METHODS:C57BL/6 m...

journal_title：Digestive diseases and sciences

authors： Yin G,Du J,Cao H,Liu X,Xu Q,Xiang M

更新日期：2015-12-01 00:00:00

abstract：:Primary hepatic lymphoma is a rare disease. We report five cases here and summarize clinical and pathologic features of our own and reported cases from Western countries and Japan. The total number of cases was 68. The age of patients ranged from 7 to 87 years (median 55) with a male-to-female ratio of 3.1:1. Chronic ...

journal_title：Digestive diseases and sciences

authors： Ohsawa M,Aozasa K,Horiuchi K,Kataoka M,Hida J,Shimada H,Oka K,Wakata Y

更新日期：1992-07-01 00:00:00

abstract：:Apoptosis is an important process in a wide variety of different biological systems. In addition to caspases, recently, calpains, another family of proteases, have been found to be involved in apoptosis of many cell systems. This study is designed with the aims to evaluate the possible effect of Z-LLY-FMK (a calpain i...

journal_title：Digestive diseases and sciences

authors： Sheen-Chen SM,Ho HT,Eng HL

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Intestinal Behcet's disease (BD) is a specific subtype of BD. Effective drug therapy for intestinal BD remains elusive. AIMS:To investigate long-term outcomes and identify predictors of sustained response in intestinal BD patients receiving infliximab (IFX) treatment. METHODS:The medical records were revie...

journal_title：Digestive diseases and sciences

authors： Zou J,Ji DN,Cai JF,Guan JL,Bao ZJ

更新日期：2017-02-01 00:00:00

abstract：:We conducted a randomized prospective study with extended intraesophageal pH monitoring on two consecutive nights to test the hypothesis that a waterbed (WB) might increase recumbent acid exposure compared to a regular bed (RB). We studied 10 controls (mean age 29 years; five males, five females) with no history of re...

journal_title：Digestive diseases and sciences

authors： Wang JC,Castell DO,Sinclair JW,Wu WC

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Topical pharyngeal anesthesia as an adjunct to intravenous sedation to facilitate gastroscopy has been widely acknowledged; however, its efficacy has not been established when it is used in patients under deep sedation with propofol. AIMS:To demonstrate the limited value of topical pharyngeal anesthesia in ...

journal_title：Digestive diseases and sciences

authors： Tsai HI,Tsai YF,Liou SC,Su MY,Lin CC,Chang CJ,Yu HP

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND AND AIM:Simultaneous dilatation of the common bile duct and pancreatic duct, "double-duct sign" (DDS), is an ominous finding concerning for pancreaticobiliary malignancy. Little evidence exists to guide the initial evaluation and subsequent follow-up for patients with DDS in the absence of jaundice or focal ...

journal_title：Digestive diseases and sciences

authors： Cohen J,Sawhney MS,Pleskow DK,Chuttani R,Patel NJ,Sheridan J,Berzin TM

更新日期：2014-09-01 00:00:00

abstract：BACKGROUND:The principle of treating-to-target has been successfully applied to many diseases with significant improvement in patient care and as a useful guidance for healthcare providers. Appreciation of the central role for arterial vasodilatation in the pathogenesis of hepatorenal syndrome (HRS) has led to routine ...

journal_title：Digestive diseases and sciences

authors： Cai CX,Maddukuri G,Jaipaul N,Zhang Z

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND AND AIMS:Patients with decompensated cirrhosis are at increased risk of mortality, even in absence of ACLF. The CLIF-C AD score (CLIF-C ADs) was proposed as a prognostic score but lacks sufficient validation. Our aim was to describe clinical characteristics and hospital evolution according to score groups an...

journal_title：Digestive diseases and sciences

authors： Baldin C,Piedade J,Guimarães L,Victor L,Duarte J,Veiga Z,Alcântara C,Fernandes F,Pereira JL,Pereira G

更新日期：2021-01-03 00:00:00

abstract：:Activation of peroxisome proliferator-activated receptor gamma (PPARgamma) has been shown to inhibit the proliferation of gastric cancer cells. A common polymorphism at codon 12 of this gene (Pro12Ala) has been shown to confer protection against diabetes and colorectal cancer. We investigated the influence of PPARgamm...

journal_title：Digestive diseases and sciences

authors： Tahara T,Arisawa T,Shibata T,Nakamura M,Wang F,Maruyama N,Kamiya Y,Nakamura M,Fujita H,Nagasaka M,Iwata M,Takahama K,Watanabe M,Hirata I,Nakano H

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND AND AIM:The liver has a high capacity of its regeneration. Most hepatic cells are quiescent unless otherwise stimulated such as their injury or ablation. A previous study suggest that pre-activated hepatic cells have a positive effect on their regeneration. In this study, we examined whether the pre-activate...

journal_title：Digestive diseases and sciences

authors： Arioka Y,Ito H,Ando T,Ogiso H,Hirata A,Hara A,Seishima M

更新日期：2015-06-01 00:00:00

abstract：:Oxygen radicals are important regulators in Helicobacter pylori-induced gastric ulceration and carcinogenesis. IL-8 may be regulated by oxidant-sensitive transcription factors, NF-kappaB, and AP-1. The present study aims to investigate whether H. pylori-induced IL-8 expression is regulated by NF-kappaB and AP-1 in gas...

journal_title：Digestive diseases and sciences

authors： Chu SH,Kim H,Seo JY,Lim JW,Mukaida N,Kim KH

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Although the use of cold snare polypectomy (CSP) has spread rapidly, its safety for pedunculated (Ip) polyps remains controversial. In particular, the outcomes of hot snare polypectomy (HSP) and CSP for Ip polyps have not been previously compared. AIMS:This study evaluated whether the rate of delayed postpo...

journal_title：Digestive diseases and sciences

authors： Arimoto J,Chiba H,Ashikari K,Fukui R,Tachikawa J,Okada N,Suto T,Kawano N,Niikura T,Kuwabara H,Nakaoka M,Ida T,Goto T,Nakajima A

更新日期：2020-07-04 00:00:00

abstract：BACKGROUND:Histological remission represents a target distinct from endoscopic healing in ulcerative colitis (UC) and seems a better predictor of clinical outcomes. AIMS:The aim of this study was to assess the ability of adalimumab to achieve histological remission in UC patients. METHODS:Single-center, retrospective...

journal_title：Digestive diseases and sciences

authors： Fernández-Blanco JI,Fernández-Díaz G,Cara C,Vera MI,Olivares D,Taxonera C

更新日期：2018-03-01 00:00:00

abstract：:We measured the effects of cimetidine on antibiotic concentrations in the luminal portion of gastric mucosa. Guinea pigs were premedicated with cimetidine 4 mg/kg intramuscularly. Clindamycin, an antibiotic previously characterized under physiologic pH conditions, was administered intramuscularly and levels measured i...

journal_title：Digestive diseases and sciences

authors： Westblom TU,Duriex DE

更新日期：1991-01-01 00:00:00

abstract：:Inhibition of monoamine oxidase B (MAO B) by selective inhibitors pargyline and L-deprenyl increases dopamine (DA) and norepinephrine (NE) concentrations in nucleus accumbens (NACB) and is associated with reduction in cold water restraint-induced gastric mucosal injury, inhibition of basal gastric acid output, and reg...

journal_title：Digestive diseases and sciences

authors： Xing LP,Washington J,Seaton J,Kauffman G Jr

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The effect of the cystic fibrosis transmembrane conductance regulator protein (CFTR) defect in pancreatic insufficient (PI) patients with cystic fibrosis (CF) on the gastrointestinal pH profile is poorly defined. Adequate and efficient neutralization of the gastric acidity in the duodenum is importa...

journal_title：Digestive diseases and sciences

authors： Gelfond D,Ma C,Semler J,Borowitz D

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVES:Lifestyle and demographic risk factors for the development of oesophageal adenocarcinoma developing from columnar-lined oesophagus are not well defined. METHODS:Demographic and lifestyle factors, endoscopy and histology reports were extracted from 1,761 subjects from seven UK centres. The associations of co...

journal_title：Digestive diseases and sciences

authors： Gatenby PA,Caygill CP,Ramus JR,Charlett A,Watson A

更新日期：2008-05-01 00:00:00

abstract：:A 68-year-old man developed hepatic injury with no hypersensitivity reaction after three years of hydralazine therapy. The liver injury histologically showed centrilobular zonal necrosis. Clinical, biochemical, and histological recovery followed discontinuation of the drug. Challenge tests and serial liver biopsies re...

journal_title：Digestive diseases and sciences

authors： Itoh S,Yamaba Y,Ichinoe A,Tsukada Y

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:Total parenteral nutrition (TPN), a necessary treatment for patients who cannot receive enteral nutrition, is associated with infectious complications due in part to a loss of intestinal epithelial barrier function (EBF). Using a mouse model of TPN, with enteral nutrient deprivation, we previously demonstrat...

journal_title：Digestive diseases and sciences

authors： Demehri FR,Krug SM,Feng Y,Lee IF,Schulzke JD,Teitelbaum DH

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Corticosteroids and pentoxifylline reduce short-term mortality in severe alcoholic hepatitis (SAH), but not to the extent desired. Combining both drugs may lead to better survival, but has not yet been studied. AIM:To compare the efficacy of corticosteroids plus pentoxifylline with that of corticosteroids a...

journal_title：Digestive diseases and sciences

authors： Sidhu SS,Goyal O,Singla P,Gupta D,Sood A,Chhina RS,Soni RK

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Gut inflammation is prevalent in chronic kidney disease (CKD) and likely contributes to systemic inflammation via disruption of the epithelial tight junction with subsequent endotoxin and bacterial translocation. AIMS:To study the expression profile of inflammatory and tight junction proteins in the colon f...

journal_title：Digestive diseases and sciences

authors： Lau WL,Liu SM,Pahlevan S,Yuan J,Khazaeli M,Ni Z,Chan JY,Vaziri ND

更新日期：2015-05-01 00:00:00

abstract：:Antimony electrodes are clinically useful because of their low cost and simple construction; they have no glass to break. There is only a few hundred ohms resistance between an antimony pH electrode and the reference electrode so that the voltage generated can be recorded with simple low-impedance recorders linked to ...

journal_title：Digestive diseases and sciences

authors： Opekun AR,Smith JL,Graham DY

更新日期：1990-08-01 00:00:00

abstract：:Peptide YY (PYY) is an important modulator of stimulated pancreatic exocrine secretion. PYY acts proximal to the acinar cell but the exact site and mechanism of action are unknown. The aim of the present study is to determine the pathway through which PYY exerts its effect on the exocrine pancreas in awake rats under ...

journal_title：Digestive diseases and sciences

authors： Deng X,Guarita DR,Wood PG,Kriess C,Whitcomb DC

更新日期：2001-01-01 00:00:00

abstract：:The destruction of the integrity of the gastric epithelial barrier underlies the pathology of many gastric diseases, including gastric tumors. The Helicobacter pylori virulence factor CagA is one of the main destroyers of the gastric epithelial barrier. There are differences among CagA proteins that originate from dif...

journal_title：Digestive diseases and sciences

authors： Wu J,Xu S,Zhu Y

更新日期：2013-07-01 00:00:00

abstract：:Ornithine decarboxylase (ODC) activity has been associated with mucosal growth and injury, yet, little information is available on ODC activity during gastric ulcer healing. We measured ODC activity in the ulcer base submucosa and the surrounding mucosa at 1 cm and 2 cm and assessed ulcer surface healing and a histolo...

journal_title：Digestive diseases and sciences

authors： Marcuard SP,Silverman JF,Finley JL,Seidel ER

更新日期：1992-07-01 00:00:00

abstract：:To investigate the possible role of pepsin in ulceration induced by hydrogen ion back-diffusion, the ratio of alkali-labile pepsinogen to total pepsinogen was studied during the course of aspirin- and taurocholate-induced gastric ulceration in comparison with the changes in the ion permeability and histological findin...

journal_title：Digestive diseases and sciences

authors： Ohe K,Yokoya H,Kitaura T,Kunita T,Miyoshi A

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:Hepatic encephalopathy (HE) is a serious neuropsychiatric complication in both acute and chronic liver disease. AIMS:To establish the utility of a portable noninvasive method to measure ammonia in the breath of healthy subjects and patients with HE. METHODS:The study included 106 subjects: 44 women and 62 ...

journal_title：Digestive diseases and sciences

authors： Adrover R,Cocozzella D,Ridruejo E,García A,Rome J,Podestá JJ

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND AND AIM:Although cholesterol levels are elevated in patients with primary biliary cirrhosis (PBC), most PBC patients are not at increased risk of dying from atherosclerotic heart disease. There is, however, a subgroup, approximately 10%, who have additional disorders of lipid metabolism. They might benefit f...

journal_title：Digestive diseases and sciences

authors： Abu Rajab M,Kaplan MM

更新日期：2010-07-01 00:00:00