Monoamine oxidase B inhibition reduces gastric mucosal blood flow, basal acid secretion, and cold water restraint-induced gastric mucosal injury in rats.

abstract：:Growth factors, such as epidermal growth factor (EGF), are known to protect upper gut mucosa against irritants and to enhance healing of ulcerative lesions in animal models. A number of salivary growth factors are found in human saliva. The aim of this study was to determine if salivary growth factors and cytokines ar...

journal_title：Digestive diseases and sciences

authors： Kongara K,Varilek G,Soffer EE

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Human hepatocellular carcinoma (HCC) is one of the most common fatal cancers and an important health problem worldwide, but its mechanism is still unclear. Microtubule (MT) kinesin motor proteins orchestrate a variety of cellular processes (e.g. mitosis, motility and organelle transportation) and have been i...

journal_title：Digestive diseases and sciences

authors： Huang X,Liu F,Zhu C,Cai J,Wang H,Wang X,He S,Liu C,Yao L,Ding Z,Zhang Y,Zhang T

更新日期：2014-04-01 00:00:00

abstract：:Rebamipide, a gastroprotective drug, is a compound selected from over 500 amino acid analogs of 2(1H)-quinolinone tested for gastroprotective action and for efficacy to heal experimental gastric ulcers. This drug stimulates prostaglandin generation in gastric mucosa and improves not only the speed but also the quality...

journal_title：Digestive diseases and sciences

authors： Arakawa T,Kobayashi K,Yoshikawa T,Tarnawski A

更新日期：1998-09-01 00:00:00

abstract：:A patient with multiple large hyperplastic (metaplastic) polyps of the colon is reported. Hundreds of polyps, some over 3 cm in size, were distributed uniformly throughout the large bowel. There was no evidence of polyps in the stomach or small intestine. The polyps, except for their large size, had the histologic fea...

journal_title：Digestive diseases and sciences

authors： Sumner HW,Wasserman NF,McClain CJ

更新日期：1981-01-01 00:00:00

abstract：:To understand whether direct transmission of H. pylori occurs from infected mouse to noninfected mouse, the system using a mouse model we developed previously was tested. Six nude mice were challenged with H. pylori inocula; one group consisted of one challenged nude mouse 1 week after inoculation raised with four non...

journal_title：Digestive diseases and sciences

authors： Karita M,Matsumoto S,Kamei T,Shinohara K,Sugiyama T

更新日期：2005-06-01 00:00:00

abstract：:Primary hepatic lymphoma is a rare disease. We report five cases here and summarize clinical and pathologic features of our own and reported cases from Western countries and Japan. The total number of cases was 68. The age of patients ranged from 7 to 87 years (median 55) with a male-to-female ratio of 3.1:1. Chronic ...

journal_title：Digestive diseases and sciences

authors： Ohsawa M,Aozasa K,Horiuchi K,Kataoka M,Hida J,Shimada H,Oka K,Wakata Y

更新日期：1992-07-01 00:00:00

abstract：:The original version of the article unfortunately contained an error in the unit used for 'Distance of propagation'. The distance of propagation should be in the unit 'cm' rather than 'mm' throughout the manuscript. ...

journal_title：Digestive diseases and sciences

authors： Jaung R,Varghese C,Lin AY,Paskaranandavadivel N,Du P,Rowbotham D,Dinning P,O'Grady G,Bissett I

更新日期：2020-08-08 00:00:00

abstract：:A pathogenic role of nitric oxide has been suggested in acute and chronic intestinal inflammation. We took the opportunity offered by studies in patients with excluded colon, which represents a model of chronic intestinal inflammation with no exogenous nitrite or nitrate supply, to evaluate the quantity and the qualit...

journal_title：Digestive diseases and sciences

authors： Neut C,Guillemot F,Colombel JF

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:HAb18G/CD147 expression has been associated with many tumor invasion molecules, which play important roles in recurrence and poor differentiation of esophageal squamous cell carcinoma (ESCC). However, the clinical implications of HAb18G/CD147 in ESCC are still unclear. AIMS:In this study, we clarified the c...

journal_title：Digestive diseases and sciences

authors： Zhu S,Li Y,Mi L,Zhang Y,Zhang L,Gong L,Han X,Yao L,Lan M,Chen Z,Zhang W

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Bloating is one of the most bothersome symptoms of irritable bowel syndrome (IBS), but its association with other symptoms is not well described. AIMS:We investigated the association between symptoms of abdominal bloating, other IBS symptoms, psychological distress, and comorbid pain conditions. METHODS:We...

journal_title：Digestive diseases and sciences

authors： Hod K,Ringel Y,van Tilburg MAL,Ringel-Kulka T

更新日期：2019-05-01 00:00:00

abstract：:There are no requirements concerning the amplitude of simultaneous contractions among the present criteria for the manometric diagnosis of diffuse esophageal spasm. The purpose of this investigation was to determine whether the current criteria effectively identify an appropriately homogenous patient population. Sixty...

journal_title：Digestive diseases and sciences

authors： Allen ML,DiMarino AJ Jr

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND:It is not known whether transjugular intrahepatic porto-systemic shunt (TIPS) is safe in patients with advanced liver cirrhosis. The aim of our study was to evaluate the impact of TIPS on transplant-free survival in patients with liver cirrhosis and MELD score ≥15. METHODS:All adult patients who underwent T...

journal_title：Digestive diseases and sciences

authors： Ascha M,Hanouneh M,S Ascha M,Zein NN,Sands M,Lopez R,Hanouneh IA

更新日期：2017-02-01 00:00:00

abstract：:To investigate the role of heredity in alcoholic pancreatitis, an HLA typing study has been performed. Patients with alcoholic pancreatitis exhibited an increased frequency of HLA Bw 39 when compared with the general population [13.6% vs 3.3%, P (corrected) less than 0.02; relative risk 4.7]. Alcoholics without pancre...

journal_title：Digestive diseases and sciences

authors： Wilson JS,Gossat D,Tait A,Rouse S,Juan XJ,Pirola RC

更新日期：1984-08-01 00:00:00

abstract：INTRODUCTION:Interpretation of video capsule data is time-consuming. Olympus capsule endoscopy (CE) software systems are equipped with auto-speed-adjusted and express-selected playback modes and overview function in an effort to reduce reading times. The clinical efficacy of these new playback features is unknown. Our ...

journal_title：Digestive diseases and sciences

authors： Subramanian V,Mannath J,Telakis E,Ragunath K,Hawkey CJ

更新日期：2012-06-01 00:00:00

abstract：:When radiolabeled 1,25-dihydroxyvitamin D3 is added to the perfusion medium of a rat liver perfusion system, a polar metabolite of 1,25-dihydroxyvitamin D3 is formed in the liver and excreted in the bile. Addition of radiolabeled 1,25-dihydroxyvitamin D3 to the perfusion medium without a liver in the circuit results i...

journal_title：Digestive diseases and sciences

authors： Kumar R,Nagubandi S,Londowski JM

更新日期：1981-03-01 00:00:00

abstract：:The association of chronic intestinal pseudoobstruction with ophthalmoplegia has been reported previously in visceral myopathies. We report a case of this association in which muscle mitochondria had a crystalline appearance, a dense core, and decreased cytochrome c oxidase and succinate cytochrome c reductase activit...

journal_title：Digestive diseases and sciences

authors： Li V,Hostein J,Romero NB,Marsac C,Mezin P,Bost R,Degoul F,Fardeau M,Fournet J

更新日期：1992-03-01 00:00:00

abstract：:The double pylorus is a fistulous communication between the gastric antrum and duodenal bulb. In most instances, it is believed to be a complication of peptic ulcer disease. In prior reports, the longest follow-up has been only 5 years. We report four cases of double pylorus, three of which have been followed medicall...

journal_title：Digestive diseases and sciences

authors： Einhorn RI,Grace ND,Banks PA

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:Subjects with fatty liver disease (FLD) can show increased hepatic 2-deoxy-2-((18)F)fluoro-D-glucose (FDG) uptake, but the role of hepatic inflammation has not been explored. AIMS:We investigated whether hepatic inflammatory response, as implicated by elevated serum markers, is associated with increased liv...

journal_title：Digestive diseases and sciences

authors： Hong SP,Noh TS,Moon SH,Cho YS,Lee EJ,Choi JY,Kim BT,Lee KH

更新日期：2014-03-01 00:00:00

abstract：:Serum levels of immunosuppressive acidic protein (IAP) were determined in 68 patients undergoing resection of colorectal cancer and 21 healthy subjects. Eighteen patients had perioperative transfusion of allogeneic blood (transfused patients) and 50 patients had no blood transfusion (nontransfused patients). Transfuse...

journal_title：Digestive diseases and sciences

authors： Iwanaga T,Suzuki H

更新日期：1999-08-01 00:00:00

abstract：AIM:Intestinal ischemia reperfusion (IR) causes tissue injury in two ways, starting a pro-inflammatory cascade and oxidative stress. The aim of this study was to investigate the possible protective effects of caffeic acid phenethyl ester (CAPE), which has antioxidant and anti-inflammatory properties, against intestinal...

journal_title：Digestive diseases and sciences

authors： Yildiz Y,Serter M,Ek RO,Ergin K,Cecen S,Demir EM,Yenisey C

更新日期：2009-04-01 00:00:00

abstract：:This study assessed the mucosal antioxidant response during acute (mouse) and chronic (adult human) H. pylori infection and following N-acetylcysteine administration. Antral biopsies were obtained from 44 patients (16 infected, 28 noninfected). Sixty-nine mice were sacrificed after 1 (n = 25), 4 (n = 28), or 6 (n = 16...

journal_title：Digestive diseases and sciences

authors： Matthews GM,Tivey D,Cummins AG,Butler RN

更新日期：2004-08-01 00:00:00

abstract：:The aim of this study was to examine the effect of the antithrombotic drugs aspirin and enoxaparin on fibrosis progression and regenerative activity in a rat model of liver cirrhosis and to determine if these two drugs are beneficial in animals with advanced fibrosis or with established cirrhosis undergoing partial he...

journal_title：Digestive diseases and sciences

authors： Assy N,Hussein O,Khalil A,Luder A,Szvalb S,Paizi M,Spira G

更新日期：2007-05-01 00:00:00

abstract：:This study evaluates the hypothesis that cerulein relaxes the sphincter of Oddi (SO) via nitric oxide (NO). The spontaneous motility and the response to cerulein on the canine SO were recorded using a constant-perfusion technique. N(G)-L-arginine-methyl-ester (L-NAME) increased the spontaneous motility and dose-depend...

journal_title：Digestive diseases and sciences

authors： Shima Y,Mori M,Harano M,Tsuge H,Tanaka N,Yamazato T

更新日期：1998-03-01 00:00:00

abstract：:Endoscopic papillary balloon dilatation (EPBD) has been recently used in conjunction with endoscopic sphincterotomy (EST) for the removal of common bile duct (CBD) stones. The present study was aimed at assessing the safety and outcome of sequential EPBD following EST for CBD stones. A total of 74 patients (43 females...

journal_title：Digestive diseases and sciences

authors： Kochhar R,Dutta U,Shukla R,Nagi B,Singh K,Wig JD

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND AIMS:The optimal algorithm to identify Lynch syndrome (LS) among patients with colorectal cancer (CRC) is unclear. The definitive test for LS, germline testing, is too expensive to be applied in all cases. Initial screening with the revised Bethesda Guidelines (RBG) cannot be applied in a considerable nu...

journal_title：Digestive diseases and sciences

authors： Gould-Suarez M,El-Serag HB,Musher B,Franco LM,Chen GJ

更新日期：2014-12-01 00:00:00

abstract：:Our purpose was to observe the effects of sodium phosphate (NaP) colonoscopy preparation on serum electrolytes, phosphate, and calcium and to identify factors associated with any adverse effects. In an unselected group of 100 consecutive patients attending for out patient colonoscopy, 45% of patients had raised serum ...

journal_title：Digestive diseases and sciences

authors： Ainley EJ,Winwood PJ,Begley JP

更新日期：2005-07-01 00:00:00

abstract：:Some endoscopic trainees find it difficult to manipulate an endoscope's controls, possibly due to small hand size. To assess this, a survey was mailed to all gastroenterology fellows in the US. Two hundred twenty-seven of 1,295 (17.5%) fellows responded. Median surgical glove size was 7.5. Ninety-three respondents (41...

journal_title：Digestive diseases and sciences

authors： Cohen DL,Naik JR,Tamariz LJ,Madanick RD

更新日期：2008-07-01 00:00:00

abstract：:Forty-nine Japanese patients were enrolled in a randomized, placebo-controlled, double-blind trial of alpha-interferon for chronic non-A, non-B hepatitis: 24 patients received 3 million units of recombinant human alpha alpha-interferon (alpha-2a) thrice weekly for eight weeks, and 25 patients received placebo in a sim...

journal_title：Digestive diseases and sciences

authors： Omata M,Ito Y,Yokosuka O,Imazeki F,Tagawa M,Takano S,Hosoda K,Tada M,Ohto M,Ito K

更新日期：1991-09-01 00:00:00

abstract：:The gold standard for measuring gastric emptying is scintigraphy, either with digestible solids or liquids. Unfortunately, this method is expensive and of limited availability. An alternative could be to use radiopaque markers (ROMs). Our aim was to compare these two tests in healthy volunteers and in patients to see ...

journal_title：Digestive diseases and sciences

authors： Stotzer PO,Fjälling M,Grétarsdóttir J,Abrahamsson H

更新日期：1999-04-01 00:00:00

abstract：AIM:The aim of this case-control study was to investigate both the distribution of MCP-1, eNOS, tPA and PAI-1 gene polymorphism and correlation of genotypes and phenotypes. METHOD:Between September 1997-January 2005, 20 patients with HPS (group 1) were compared with a group of cirrhotic patients (group 2, n = 19) as w...

journal_title：Digestive diseases and sciences

authors： Tumgor G,Berdeli A,Arikan C,Levent E,Aydogdu S

更新日期：2008-05-01 00:00:00