Eosinophilic gastroenteritis: a review.

abstract：:Phosphorylation/dephosphorylation of intracellular proteins are important steps in the regulation of cell growth. Okadaic acid, an inhibitor of the serine/threonine protein phosphatases 1 and 2A, is a potent tumor promoter. This effect may be through the inhibition of dephosphorylation (termed "hyperphosphorylation") ...

journal_title：Digestive diseases and sciences

authors： Hirai A,Bold RJ,Ishizuka J,Hirai M,Townsend CM Jr,Thompson JC

更新日期：1996-10-01 00:00:00

abstract：:The bile acids in brown pigment stones and gallbladder bile were fractionated into free acids, glycine and taurine conjugates, and sulfates using diethylaminohydroxypropyl Sephadex LH-20 (DEAP-LH-20) column chromatography and were quantitated by gas chromatography. Twenty-eight cases of brown pigment stones were studi...

journal_title：Digestive diseases and sciences

authors： Akiyoshi T,Nakayama F

更新日期：1990-01-01 00:00:00

abstract：:Possible differences in the abilities of esophageal body and lower esophageal sphincter muscles to utilize substrates to support agonist-induced contractions were studied. Strips of longitudinal, circular, and lower esophageal sphincter muscle from the opossum esophagus were first contracted to approximately 70% of th...

journal_title：Digestive diseases and sciences

authors： Percy WH,Sutherland J,Christensen J

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND AND AIMS:The timing of menarche in Crohn's disease (CD) is poorly described. Our objectives were to study age at menarche onset in CD, and factors associated with this. METHODS:We compared the age at menarche of 34 CD patients with that for 545 controls, using data in the National Health and Nutrition Exami...

journal_title：Digestive diseases and sciences

authors： Gupta N,Lustig RH,Kohn MA,Vittinghoff E

更新日期：2012-11-01 00:00:00

abstract：INTRODUCTION:A significant proportion of patients with Crohn's disease (CD) lose response to antibodies directed against tumor necrosis factor α (TNF). Prior TNF-antagonist failure is associated with lower rates of response to subsequent TNF-antagonist therapy. In patients failing two anti-TNF agents, a choice exists b...

journal_title：Digestive diseases and sciences

authors： Ananthakrishnan AN,Hur C,Korzenik JR

更新日期：2012-02-01 00:00:00

abstract：:We previously demonstrated that false-positive findings for tumor markers are frequently observed, and that the sensitivity of marker monitoring for early detection of the recurrence is low after curative resection of gastric cancer. The aim of this study was to investigate whether such characters are specific to gast...

journal_title：Digestive diseases and sciences

authors： Ohtsuka T,Nakafusa Y,Sato S,Kitajima Y,Tanaka M,Miyazaki K

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Assessment and quantification of actual liver function is crucial in patients with chronic liver disease to monitor disease progression and predict individual prognosis. Mathematical models, such as model for end-stage liver disease, are used for risk stratification of patients with chronic liver disease but...

journal_title：Digestive diseases and sciences

authors： Malinowski M,Jara M,Lüttgert K,Orr J,Lock JF,Schott E,Stockmann M

更新日期：2014-12-01 00:00:00

abstract：:Choledochoduodenostomy may be followed by the "sump syndrome." This previously required surgical intervention. We describe the successful application of endoscopic therapy in two patients with this syndrome. ...

journal_title：Digestive diseases and sciences

authors： Barkin JS,Silvis S,Greenwald R

更新日期：1980-08-01 00:00:00

abstract：BACKGROUND:Eosinophilic esophagitis (EoE) is defined by a minimum of 15 eosinophils (eos) per high-powered field (HPF) on esophageal biopsy, along with esophageal symptoms and the exclusion of gastroesophageal reflux (GERD). The clinical significance of fewer eosinophils is unknown. METHODS:Fifty-nine adult patients w...

journal_title：Digestive diseases and sciences

authors： Ravi K,Talley NJ,Smyrk TC,Katzka DA,Kryzer L,Romero Y,Arora AS,Alexander JA

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND AND AIMS:The optimal algorithm to identify Lynch syndrome (LS) among patients with colorectal cancer (CRC) is unclear. The definitive test for LS, germline testing, is too expensive to be applied in all cases. Initial screening with the revised Bethesda Guidelines (RBG) cannot be applied in a considerable nu...

journal_title：Digestive diseases and sciences

authors： Gould-Suarez M,El-Serag HB,Musher B,Franco LM,Chen GJ

更新日期：2014-12-01 00:00:00

abstract：:Previous studies showed that bile salts had a promoting effect on colon cancer development and this effect was inhibited by ursodeoxycholate (UDC). We recently found that both human colorectal adenomas and carcinomas were associated with a specific decrease in alkaline sphingomyelinase activity. In this work, we compa...

journal_title：Digestive diseases and sciences

authors： Duan RD,Cheng Y,Tauschel HD,Nilsson A

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:Thymoquinone (TQ) is the major constituent of Nigella sativa seed and has shown biological activity in various human carcinomas. However, few studies have reported its effect on esophageal carcinoma (EC). AIMS:To explore the chemosensitive effect and mechanism of TQ in augmentation of cisplatin (DDP)-induce...

journal_title：Digestive diseases and sciences

authors： Hu X,Ma J,Vikash V,Li J,Wu D,Liu Y,Zhang J,Dong W

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:The high mobility group protein A2 (HMGA2) is an architectural transcription factor that plays an important role in the development and progression of many malignant neoplasms. High expression of HMGA2 in gastric cancer correlates with invasiveness of cancer and is an independent prognostic factor. The reaso...

journal_title：Digestive diseases and sciences

authors： Zha L,Zhang J,Tang W,Zhang N,He M,Guo Y,Wang Z

更新日期：2013-03-01 00:00:00

abstract：:Minimal hepatic encephalopathy (MHE) describes patients with chronic liver disease or cirrhosis who have no clinical symptoms of brain dysfunction but perform worse on psychometric tests compared with healthy subjects. The pathogenesis of hepatic encephalopathy is controversial although ammonia has been found to induc...

journal_title：Digestive diseases and sciences

authors： Malaguarnera M,Greco F,Barone G,Gargante MP,Malaguarnera M,Toscano MA

更新日期：2007-11-01 00:00:00

abstract：:Small bowel tumors are rare, accounting for 1-2% of all gastrointestinal neoplasms. We sought to determine the diagnostic and therapeutic impact of double-balloon enteroscopy (DBE) in patients with small bowel tumors. Between January 2005 and March 2008, 78 patients underwent 96 DBE. All nine patients (seven males; me...

journal_title：Digestive diseases and sciences

authors： Almeida N,Figueiredo P,Lopes S,Gouveia H,Leitão MC

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Notch signaling is required for the maintenance of intestinal epithelial proliferation. Dysfunction of this signaling pathway is associated with the loss of proliferated crypt epithelial cells. AIM:The aim of this study was to investigate the role of Notch signaling in small bowel resection (SBR)-associated...

journal_title：Digestive diseases and sciences

authors： Chen G,Sun L,Yu M,Meng D,Wang W,Yang Y,Yang H

更新日期：2013-09-01 00:00:00

abstract：:A 68-year-old man developed hepatic injury with no hypersensitivity reaction after three years of hydralazine therapy. The liver injury histologically showed centrilobular zonal necrosis. Clinical, biochemical, and histological recovery followed discontinuation of the drug. Challenge tests and serial liver biopsies re...

journal_title：Digestive diseases and sciences

authors： Itoh S,Yamaba Y,Ichinoe A,Tsukada Y

更新日期：1980-11-01 00:00:00

abstract：:This study aimed at establishment of adequate evaluation of intestinal viability before release of the strangulated intestine by measuring electrical properties. In rats a 20-cm segment of the distal ileum and mesentery was strangulated. The intestine was strangulated for 0, 2, 15, 45, 90, and 120 min. The conductance...

journal_title：Digestive diseases and sciences

authors： Matsuo H,Hirose H,Mori Y,Takagi H,Iwata H,Yamada T,Sakamoto K,Yasumura M

更新日期：2004-04-01 00:00:00

abstract：:We studied intraesophageal pressure changes in patients with symptoms of gastroesophageal reflux and an abnormal 24-hr pH monitoring record (N = 52). Our method was simultaneous esophageal manometry and pH monitoring. We observed a three-component esophageal manometric sequence (EMS). When this sequence recurred over ...

journal_title：Digestive diseases and sciences

authors： Shay SS,Eggli D,Oliver G,Peura DA,Johnson LF

更新日期：1989-09-01 00:00:00

abstract：:A case of small bowel ulceration and perforation possibly due to therapy with Klotrix in a patient with Crohn's disease is presented. Following emergent surgery with creation of a diverting loop jejunostomy, subsequent reestablishment of intestinal continuity was carried out with excellent clinical results. Gastrointe...

journal_title：Digestive diseases and sciences

authors： Brower RA

更新日期：1986-12-01 00:00:00

abstract：BACKGROUND:Acute variceal bleeding (AVB) in patients with cirrhosis is associated with high mortality, ranging from 12 to 20% at 6 weeks. The existing prognostic models for AVB lack precision and require further validation. AIM:In this prospective study, we aimed to develop and validate a new prognostic model for AVB,...

journal_title：Digestive diseases and sciences

authors： Rout G,Sharma S,Gunjan D,Kedia S,Saraya A,Nayak B,Singh V,Kumar R,Shalimar

更新日期：2019-08-01 00:00:00

abstract：:We investigated the effect of pH change on octapeptide cholecystokinin's ability to contract guinea pig gallbladder strips. In the absence of exogenous drugs, pH changes had no demonstrable effect on gallbladder tension. However, when gallbladder strips were contracted with CCK-OP at pH 7.3, increasing the pH in the m...

journal_title：Digestive diseases and sciences

authors： La Morte WW,Hingston S,Matolo N,Birkett DH,Williams LF Jr

更新日期：1982-07-01 00:00:00

abstract：BACKGROUND:The use of proton pump inhibitors (PPIs) is thought to increase the incidence of microscopic colitis (MC), although the exact mechanisms are not fully understood. Increased infiltration of intraepithelial lymphocytes (IELs) is a pathologic finding of MC (including collagenous or lymphocytic colitis). AIMS:W...

journal_title：Digestive diseases and sciences

authors： Yu YH,Han DS,Choi EY,Park HS,Jeong JY,Eun CS,Oh YH,Pyo JY

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Average-risk women aged 50-59 years have a lower incidence and mortality of colorectal cancer relative to age-matched men, calling into question the benefit of screening colonoscopy in this age group. AIMS:We aimed to determine whether FOBT is an effective initial screening test in 50-59-year-old women. ME...

journal_title：Digestive diseases and sciences

authors： Mooers HM,Holub JL,Lieberman DA

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Eosinophilic esophagitis is among the causes of refractory reflux disease. Biopsy of esophagus is the gold standard for diagnosis. In this study we determined the frequency of eosinophilic esophagitis (EE) in refractory reflux cases referred to Motility Department of Shahid Beheshti Research Center of Gastro...

journal_title：Digestive diseases and sciences

authors： Foroutan M,Norouzi A,Molaei M,Mirbagheri SA,Irvani S,Sadeghi A,Derakhshan F,Tavassoli S,Besharat S,Zali M

更新日期：2010-01-01 00:00:00

abstract：:The aim of our prospective randomized study involving 100 patients was to investigate whether Doppler ultrasound can be used to select patients at risk for ulcer rebleeding. Ulcers in the Forrest group classified as having a visible vessel or a clot were treated prophylactically by injection with epinephrine solution....

journal_title：Digestive diseases and sciences

authors： Kohler B,Maier M,Benz C,Riemann JF

更新日期：1997-07-01 00:00:00

abstract：:Peutz-Jeghers syndrome (PJS) is an autosomal-dominant inherited disorder characterized by mucocutaneous pigmentation, hamartomatous polyposis of the gastrointestinal tract, and an increased risk for the development of both gastrointestinal and extraintestinal malignancies. Germline mutation of the STK11 gene, which en...

journal_title：Digestive diseases and sciences

authors： Gao Y,Zhang FM,Huang S,Wang X,Zhang P,Huang XD,Ji GZ,Fan ZN

更新日期：2010-04-01 00:00:00

abstract：:Pancreatic polypeptide (PP) has been shown to be released postprandially in several species. In this study we tested the efficacy of an amino acid solution (905 mOsM), 0.1 N HCl (300 mOsM), 905 mOsM NaCl, 300 mOsM glucose, corn oil, and balloon distention within the stomach, duodenum, or ileum in stimulating release o...

journal_title：Digestive diseases and sciences

authors： Duke GE,Kimmel JR,Durham K,Pollock HG,Bertoy R,Rains-Epstein D

更新日期：1982-09-01 00:00:00

abstract：BACKGROUND AND AIM:Self-expandable metal stents (SEMSs) have been a good treatment option for malignant intestinal obstruction. However, stent placement with a gastroscope can be technically difficult for the distal duodenum obstruction. A side-viewing duodenoscope may be helpful for these patients. We report our exper...

journal_title：Digestive diseases and sciences

authors： Park JM,Min BH,Lee SH,Chung KH,Lee JM,Song BJ,Lee JK,Ryu JK,Kim YT

更新日期：2015-02-01 00:00:00

abstract：:The role of carbonic anhydrase in the process of proximal duodenal mucosal bicarbonate secretion was investigated in the guinea pig. In a series of experiments in vivo, the duodenum was perfused with 24 mmol/liter NaHCO3 solution (+ NaCl for isotonicity) to ensure that active duodenal HCO3- secretion against a concent...

journal_title：Digestive diseases and sciences

authors： Muallem R,Reimer R,Odes HS,Schwenk M,Beil W,Sewing KF

更新日期：1994-05-01 00:00:00