Abstract：
:The aim of our prospective randomized study involving 100 patients was to investigate whether Doppler ultrasound can be used to select patients at risk for ulcer rebleeding. Ulcers in the Forrest group classified as having a visible vessel or a clot were treated prophylactically by injection with epinephrine solution. In the Doppler group, in contrast, only ulcers with a positive Doppler signal were treated endoscopically. In the Doppler group, rebleeds occurred significantly less frequently (2%, P < 0.03) than in the Forrest group (14%). Emergency surgery was only necessary in the Forrest group (0% vs 5%; P = 0.02). Bleeding-related mortality was 0% and 4% (P = 0.15) and the overall mortality 0% and 10% (P = 0.02), in the Doppler and Forrest groups, respectively. These results appear to show that Doppler-based injection treatment is superior to endoscopic treatment based exclusively on the Forrest classification. In our study, Doppler-based local endoscopic treatment reduced the danger of a rebleed and thus the number of emergency operations and the overall mortality.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Kohler B,Maier M,Benz C,Riemann JFdoi
10.1023/a:1018877602113subject
Has Abstractpub_date
1997-07-01 00:00:00pages
1370-4issue
7eissn
0163-2116issn
1573-2568journal_volume
42pub_type
临床试验,杂志文章,随机对照试验abstract：BACKGROUND AND AIM:Atelectasis is one of the pulmonary complications associated with anesthesia. Little is known about atelectasis following endoscopic procedures under deep sedation. This study evaluated the frequency, risk factors, and clinical course of atelectasis after endoscopic resection. METHODS:A total of 349...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-015-3844-0
更新日期：2016-01-01 00:00:00
abstract：:Alterations of small intestinal sensory thresholds and small intestinal dysmotility are associated with functional dyspepsia. Because gastric and duodenal afferents partly project to the same areas, we postulated that patients with functional dyspepsia and H. pylori infection would be characterized by lower duodenal s...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF02088548
更新日期：1996-07-01 00:00:00
abstract：:Although transient increases in intracellular Ca2+ ([Ca2+]i) underlie a number of important physiological processes, sustained elevations in [Ca2+]i mediate damage to a number of tissues and cell types including gastric mucosal cells. Increases in [Ca2+]i can activate phospholipid hydrolysis via increases in phospholi...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1026688819939
更新日期：1999-03-01 00:00:00
abstract：:The time-dependent appearance of phospholipase A2 (PLA2) activity in the preservation media of ischemic rat intestinal grafts is described. In controls, Ca2+-dependent, secretory PLA2 activity accumulated rapidly during the first 6 hr of ischemia, followed by a linear increase for up to 48 hr. LDH levels, by contrast,...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1018876717308
更新日期：1997-05-01 00:00:00
abstract：:Probiotic bacteria exhibit a variety of properties, which are unique to a particular strain. Lactobacillus acidophilus-SDC 2012, 2013 are new strains isolated from Korean infants' feces. The potential utility of Lactobacillus acidophilus-SDC 2012, 2013 in irritable bowel syndrome (IBS) was studied. Forty IBS patients ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,随机对照试验
doi：10.1007/s10620-007-0196-4
更新日期：2008-10-01 00:00:00
abstract：BACKGROUND:Different factors have been associated with prolonged fluoroscopy time (FT) during endoscopic retrograde cholangiopancreatography (ERCP). AIM:We hypothesize that FT depends on both the anatomical location of the pathology managed during ERCP and the complexity of the ERCP. METHODS:Three centers participate...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,多中心研究
doi：10.1007/s10620-014-3508-5
更新日期：2015-06-01 00:00:00
abstract：:Development of type 1 insulin-dependent diabetes mellitus has been recently reported in patients who underwent interferon-alpha (IFN-alpha) therapy because of chronic viral hepatitis. Furthermore IFN-alpha seems to be involved in the immunological events that lead to beta-cell destruction and development of type 1 dia...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF02087923
更新日期：1996-08-01 00:00:00
abstract：:Celiac disease (CD) is an immune-mediated enteropathy triggered by dietary ingestion of gluten in genetically susceptible patients. CD is often diagnosed by a "case-finding" approach of symptomatic patients. In recent times, the diagnostic paradigm has shifted to investigate patients who may be asymptomatic, but are a...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,评审
doi：10.1007/s10620-020-06352-w
更新日期：2020-08-01 00:00:00
abstract：:The synthetic substrate cholyl-PABA, developed by conjugating cholic acid with paraaminobenzoic acid, is hydrolyzed by the bacterial enzyme cholyl hydrolase to release free PABA. This study aimed to evaluate whether quantitating urinary excretion of PABA after oral administration of cholyl-PABA can detect small intest...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1005428703993
更新日期：2000-03-01 00:00:00
abstract：BACKGROUND:Lymphocytic esophagitis is a rare esophageal condition. Our knowledge of potential risk factors and treatment outcomes of lymphocytic esophagitis is limited. AIM:To investigate potential risk factors associated with the development of lymphocytic esophagitis and compare clinical characteristics and treatmen...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-020-06706-4
更新日期：2020-11-20 00:00:00
abstract：BACKGROUND:Liver metastasis is an indicator of unfavorable responses to immunotherapy in colorectal cancer patients. However, the difference of immune microenvironment between primary tumors and liver metastases has not been well understood. PATIENTS AND METHODS:Fifty-four colon cancer with liver metastasis patients w...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-020-06203-8
更新日期：2020-03-19 00:00:00
abstract：:Of 112 patients with peptic ulcer disease examined for oral carriage of Candida, 66 (59%) were carriers. Candida carriage was associated with blood group O (P < 0.05) and, independently, with nonsecretion of blood group antigens (P < 0.01). For each subject, the presence or absence of yeasts was found to be a constant...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01308603
更新日期：1993-08-01 00:00:00
abstract：OBJECTIVE:To prospectively evaluate the frequency of upper gastrointestinal symptoms and associated disorders in morbidly obese patients with endoscopy and histology prior to their gastric bypass surgery in comparison with age- and sex-matched nonobese control subjects. METHODS:All patients who were scheduled to under...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-008-0485-6
更新日期：2009-06-01 00:00:00
abstract：:A new extracorporeal piezoelectric lithotripter was tested for its gallstone disintegration capability. A total of 177 surgically removed gallbladder stones were submitted to piezoelectric shock-wave treatment. Prior to shock-wave application, the diameter, weight, and volume of all the stones and CT density and MR si...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01536364
更新日期：1989-07-01 00:00:00
abstract：:The evaluation of suspected esophageal chest pain is frustrating because of difficulty in clearly implicating the esophagus. Balloon distention was considered as a new provocative test in the esophagus because it has been shown to safely produce pain in other hollow gastrointestinal organs. Studies were performed in 5...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章
doi：10.1007/BF01299805
更新日期：1986-12-01 00:00:00
abstract：BACKGROUND:Computed tomography (CT) and magnetic resonance (MR) enterography are now widely used to diagnose and monitor Crohn's disease. AIM:We sought to assess the use of enterography for management of inflammatory bowel disease (IBD) in our medical center. METHODS:We performed a retrospective review of all patient...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-013-2964-7
更新日期：2014-04-01 00:00:00
abstract：:This study was undertaken to investigate the effect of ingestion of 80 g Vivonex on gallbladder volume, plasma cholecystokinin (CCK), and pancreatic polypeptide (PP) in eight healthy volunteers and to compare the results with those obtained after ingestion of 60 ml corn oil. Gallbladder volumes were measured by ultras...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01296686
更新日期：1987-01-01 00:00:00
abstract：:Little information on functional status and well-being is available in patients with functional gastrointestinal disease. We aimed to evaluate whether quality of life is poorer in patients with functional dyspepsia. A consecutive sample of 73 patients with functional dyspepsia completed a validated questionnaire prior...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF02064375
更新日期：1995-03-01 00:00:00
abstract：:Autoimmune hepatitis (AIH) is rare in Asian countries compared to the West, and an exceptionally low prevalence was noted previously in Taiwan. Using the revised criteria of the IAIHG, 48 cases of AIH patients were diagnosed. All patients were consecutively diagnosed over a period of 5 years. Detailed medical historie...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-005-9068-y
更新日期：2006-11-01 00:00:00
abstract：:To determine if organic anions contribute to the diarrhea of inflammatory bowel disease, we measured osmolality, electrolytes, short-chain fatty acids, lactic acid, and some Krebs cycle anions in 24-hr fecal collections from 18 patients with chronic ulcerative colitis, 20 with Crohn's disease of the colon, and 16 norm...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01536987
更新日期：1988-11-01 00:00:00
abstract：:The motor function of the gallbladder after partial distal gastrectomy for gastric carcinoma (Billroth-I reconstruction) and its relationship to the motor function of the stomach was investigated using a double-isotope method. In this method, [99mTc]N-54-pyridoxyl-5-methyltryptophan ([99mTc]PMT) was utilized as a trac...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF02064968
更新日期：1995-04-01 00:00:00
abstract：:In recent years, a number of comprehensive reviews have been written on inherited intestinal polyposis syndromes (1-7), but none has dealt specifically with Gardner's syndrome and none has focused on basic research being carried out in an attempt to understand this syndrome and to improve the medical management of aff...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,评审
doi：10.1007/BF01308046
更新日期：1980-12-01 00:00:00
abstract：:Gastrin-secreting tumors have been identified in ectopic locations including the ovary; the mechanisms regulating gastrin gene expression, its distribution, and signaling pathways in these ectopic tissues are not known. The purpose of our present study was to determine: (1) whether the gastrin gene and peptide could b...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1018846311239
更新日期：1998-07-01 00:00:00
abstract：:The early rebound in serum HCV RNA during HCV dynamic studies with high-dose interferon may be due to de novo infection with interferon escape quasispecies. We simultaneously measured serum alanine aminotransferase (ALT) and HCV RNA at rapid intervals in chronic HCV liver disease patients during interferon therapy alo...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1021798701772
更新日期：2003-01-01 00:00:00
abstract：:In this study we investigated the relative vascular response of different locations of the gastrointestinal tract to continuous intravenous infusion of isoproterenol (0.1 microgram kg-1 min-1 for 10 min). The vascular response of some nonsplanchnic organs was also examined. Blood flow of the arteries was measured by e...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01536997
更新日期：1988-11-01 00:00:00
abstract：:If an effective hepatic assist system existed, it could serve as a bridge to transplantation. Most of the patients waiting for liver transplantation have chronic liver insufficiency but are not in hepatic coma. Various hepatic assist systems have been used to salvage patients with acute liver insufficiency. Most attem...
journal_title：Digestive diseases and sciences
pub_type： 历史文章,杂志文章,评审
doi：10.1007/BF01307531
更新日期：1991-09-01 00:00:00
abstract：:The aims of our randomized, single-blind trial involving 49 patients were to study the efficacy, side effects, and tolerance of metronidazole and satranidazole in patients of amebic liver abscess. Twenty-five patients received metronidazole (800 mg TID) and 24 received satranidazole (300 mg TID with placebo at mealtim...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s10620-006-9111-7
更新日期：2006-12-01 00:00:00
abstract：:The neutralizing capacity of two antacids (Alucol = A, Syntrogel = S), differing both in their composition and theoretical neutralizing capacity, was evaluated in vitro and in vivo. In vitro at pH 3.5, 1 ml of A or S neutralizes 3.9 and 1.6 meq of acid, respectively, in an aqueous solution. When tested in vivo in the ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01320257
更新日期：1985-06-01 00:00:00
abstract：:A 24-year-old white woman presented with abdominal discomfort associated with a firm, nonpulsatile hepatic mass. Radiological examination, which included radionuclide liver scan, abdominal ultrasonography, computed tomography, and hepatic angiography, demonstrated a large, globular, multilocular cyst arising from the ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01296059
更新日期：1986-08-01 00:00:00
abstract：:Hereditary type 2 diabetes mellitus is a risk factor for chronic liver disease, and ~30 % of patients with liver cirrhosis develop diabetes. Diabetes mellitus has been associated with cirrhotic and non-cirrhotic hepatitis C virus liver infection, can aggravate the course the liver infection, and can induce a lower sus...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,评审
doi：10.1007/s10620-015-3907-2
更新日期：2016-02-01 00:00:00
