Effect of ribavirin and amantadine on early hepatitis C virus RNA rebound and clearance in serum during daily high-dose interferon.

abstract：:We examined the influences of aging on gastric damage and gastric mucosal blood flow (GMBF) responses induced by acid back-diffusion, following the barrier disruption, and investigated the relation of capsaicin-sensitive sensory nerves to these changes. Male Fischer rats 3, 13, and 24 months old were used. Under ureth...

journal_title：Digestive diseases and sciences

authors： Miyake H,Inaba N,Kato S,Takeuchi K

更新日期：1996-02-01 00:00:00

abstract：:Orlistat (tetrahydrolipstatin) is a potent inhibitor of gastric and pancreatic lipase activity causing a diminution of free fatty acids in the intestinal lumen. The release of cholecystokinin (CCK) critically depends on the presence of free fatty acids in the small intestine. Postprandial CCK release and gallbladder c...

journal_title：Digestive diseases and sciences

authors： Froehlich F,Hartmann D,Guezelhan C,Gonvers JJ,Jansen JB,Fried M

更新日期：1996-12-01 00:00:00

abstract：:Autoimmune hepatitis has two major variant phenotypes in which the features of classical disease are co-mingled with those of primary biliary cirrhosis or primary sclerosing cholangitis. These overlap syndromes lack codified diagnostic criteria, established pathogenic mechanisms, and confident management strategies. T...

journal_title：Digestive diseases and sciences

authors： Czaja AJ

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Pancreatic leaks occur as a complication of upper gastrointestinal surgery, acute pancreatitis, or abdominal trauma. Pancreatic fistulas and leaks are primarily managed conservatively. Overall, conservative measures are successful in more than half of cases. Whenever conservative treatment is not efficient, ...

journal_title：Digestive diseases and sciences

authors： Mutignani M,Dokas S,Tringali A,Forti E,Pugliese F,Cintolo M,Manta R,Dioscoridi L

更新日期：2017-10-01 00:00:00

abstract：:Gastric stasis and duodenogastric reflux have each been implicated in the pathogenesis of various upper gastrointestinal disorders. However, the relationship between intragastric bile and gastric emptying has not been explored. In each of nine healthy volunteers (seven men and two women, ages 22-47 years), gastric emp...

journal_title：Digestive diseases and sciences

authors： Parr NJ,Baker PR,Grime JS,Mackie CR

更新日期：1988-03-01 00:00:00

abstract：:We previously reported that various gastric irritants induced both apoptosis and necrosis in cultured gastric mucosal cells. In a continuation of this work, the present study has examined the effects of prostaglandin E2 (PGE2), a cytoprotective factor for gastric mucosa in vivo, on gastric irritant-induced apoptosis a...

journal_title：Digestive diseases and sciences

authors： Hoshino T,Takano T,Tsutsumi S,Tomisato W,Tsuchiya T,Mizushima T

更新日期：2002-10-01 00:00:00

abstract：INTRODUCTION:Readmission for achalasia treatment is associated with significant morbidity and cost. Factors predictive of readmission would be useful in identifying patients at risk. METHODS:We performed a retrospective study using the Nationwide Readmission Database for the year 2016 and 2017. We collected data on ho...

journal_title：Digestive diseases and sciences

authors： Gupta K,Khan A,Chalhoub J,Groudan K,Desilets D

更新日期：2021-01-01 00:00:00

abstract：:Viral dynamic studies in chronic hepatitis C virus (HCV) infection indicate a significantly shortened survival of virus-infected cells. Since at the steady state of chronic viral infection, the rate of infected cell elimination equals new cell regeneration, this would imply a high rate of hepatocyte turnover in chroni...

journal_title：Digestive diseases and sciences

authors： Lake-Bakaar G,Mazzoccoli V,Ruffini L

更新日期：2002-07-01 00:00:00

abstract：:The effects of chronic normovolemic anemia on gastric microcirculation and gastric mucosal susceptibility to ethanol-induced gastric damage were investigated in anesthetized rats. Blood exchange by a plasma expander during four consecutive days rendered the animals anemic with a 34% decrease in the baseline hematocrit...

journal_title：Digestive diseases and sciences

authors： Marroni N,Casadevall M,Panés J,Piera C,Jou JM,Pique JM

更新日期：1994-04-01 00:00:00

abstract：:Transient delayed gastric emptying is reported as a frequent complication following pancreas-preserving pancreaticoduodenectomy (PPW). We placed serosal electrodes on the stomach of a patient undergoing PPW. Myoelectric recordings were obtained postoperatively and correlated with simultaneous radionuclide liquid gastr...

journal_title：Digestive diseases and sciences

authors： Hocking MP,Harrison WD,Sninsky CA

更新日期：1990-10-01 00:00:00

abstract：:Mutations in the gene encoding the CYP2C-19 enzyme for PPI metabolism have been shown to enhance the chance for a cure in a H. pylori-positive patients using a two-week dual-therapy regimen involving omeprazole and amoxicillin. However, the impact of CYP2C-19 genetic polymorphism on eradication rates of a one-week tri...

journal_title：Digestive diseases and sciences

authors： Miwa H,Misawa H,Yamada T,Nagahara A,Ohtaka K,Sato N

更新日期：2001-11-01 00:00:00

abstract：:Patients with persistently normal ALT affected with HCV-related chronic hepatitis exist. The natural history of liver disease in these patients was demonstrated to be very slow and progression to cirrhosis likely absent. The case we report describes the occurrence of hepatocellular carcinoma (HCC) in a patient with pe...

journal_title：Digestive diseases and sciences

authors： Persico M,Palmentieri B,Coppola L,Di Giacomo Russo G,De Marino F,De Sio I,Torella R

更新日期：2002-11-01 00:00:00

abstract：:Glutamine synthetase is responsible for the ATP-dependent amidation of glutamate to glutamine. In liver the enzyme is highly localized in perivenous hepatocytes; in brain the enzyme is localized in astrocytes. Portacaval anastomosis resulted in liver atrophy, hyperammonemia, and up to 90% loss of glutamine synthetase ...

journal_title：Digestive diseases and sciences

authors： Girard G,Butterworth RF

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Birth characteristics, including weight and gestational age, may be associated with risk of Barrett's esophagus (BE), the only known precursor for esophageal adenocarcinoma; however, data are limited. AIMS:To examine associations between various birth characteristics and BE, and whether these associations a...

journal_title：Digestive diseases and sciences

authors： Shiota S,El-Serag HB,Thrift AP

更新日期：2016-04-01 00:00:00

abstract：:The mechanism by which alcohol causes pancreatic damage is still largely unknown. One important contributory factor may be the endothelins, potent vasoconstricting endothelial-derived peptides. The aim of this study was to examine in vivo endothelin release from the pancreatic vascular endothelium after alcohol ingest...

journal_title：Digestive diseases and sciences

authors： Lewis MP,Reber PU,Kusske AM,Toyama MT,Todd KE,Ashley SW,Reber HA

更新日期：1998-05-01 00:00:00

abstract：:Radionuclide gastric solid-phase emptying was studied in 10 subjects with diabetic gastroparesis comparing the acute intravenous administration of cisapride (2.5, 5, 10 mg), placebo, and metoclopramide (10 mg). No hemodynamic or electrocardiographic changes were noted. While both cisapride and metoclopramide normalize...

journal_title：Digestive diseases and sciences

authors： McHugh S,Lico S,Diamant NE

更新日期：1992-07-01 00:00:00

abstract：:Sera from Japanese patients with chronic liver disease were tested for hepatitis B virus (HBV) markers and antibodies to hepatitis C virus (anti-HCV), and the results were correlated to the presence of hepatocellular carcinoma. In chronic non-A, non-B liver disease, anti-HCV prevalence was high both in patients with h...

journal_title：Digestive diseases and sciences

authors： Yuki N,Hayashi N,Kasahara A,Hagiwara H,Katayama K,Fusamoto H,Kamada T

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:Corticotropin-releasing factor (CRF) peptides exert profound effects on the secretomotor function of the gastrointestinal tract. Nevertheless, despite the presence of CRF peptides and receptors in colonic tissue, their influence on colonic blood flow (CBF) is unknown. AIM:To determine the effect and mechani...

journal_title：Digestive diseases and sciences

authors： Akiba Y,Kaunitz JD,Million M

更新日期：2015-04-01 00:00:00

abstract：:There is, currently, no consensus with regard to the role of endoscopy in the etiologic investigation of asymptomatic pemenopausal women suffering from iron deficiency anemia (IDA). We conducted a retrospective case-control study to evaluate the contribution of esophagogastroduodenoscopy (EGD) and colonoscopy to the e...

journal_title：Digestive diseases and sciences

authors： Park DI,Ryu SH,Oh SJ,Yoo TW,Kim HJ,Cho YK,Sung IK,Sohn CI,Jeon WK,Kim BI

更新日期：2006-12-01 00:00:00

abstract：:Anorectal manometry was performed in 40 women, who consulted for functional disorders of the lower gastrointestinal tract and had been sexually abused. Anismus, defined as a rise in anal pressure during straining, was observed in 39 of 40 abused women, but in only six of 20 healthy control women (P < 0.0001). Other pa...

journal_title：Digestive diseases and sciences

authors： Leroi AM,Berkelmans I,Denis P,Hémond M,Devroede G

更新日期：1995-07-01 00:00:00

abstract：INTRODUCTION:Voluntary muscle activity, including swallowing, decreases during the night. The association between nocturnal awakenings and swallowing activity is under-researched with limited information on the frequency of swallows during awake and asleep periods. AIM:The aim of this study was to assess nocturnal swa...

journal_title：Digestive diseases and sciences

authors： Pohl D,Arevalo F,Singh E,Freeman J,Tutuian R,Castell DO

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Avoidance of gluten is critical for individuals with celiac disease (CD), but there is also concern that "extreme vigilance" to a strict gluten-free diet may increase symptoms such as anxiety and fatigue, and therefore, lower quality of life (QOL). We examined the associations of QOL with energy lev...

journal_title：Digestive diseases and sciences

authors： Wolf RL,Lebwohl B,Lee AR,Zybert P,Reilly NR,Cadenhead J,Amengual C,Green PHR

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Prior to the consensus guideline conference in 2007, eosinophilic esophagitis (EoE) was uncommon dominated by the fibrostenotic phenotype, but over the past decade has become a common cause of dysphagia with more inflammatory phenotypes diagnosed. We assessed the impact of guideline definitions on t...

journal_title：Digestive diseases and sciences

authors： Lipka S,Boyce HW,Kumar A,Richter JE

更新日期：2015-06-01 00:00:00

abstract：:It has not been fully understood how intact protein antigens escape digestion in the course of absorption. The present study was designed to investigate the mechanism that heat stress induced an increase in intact protein antigen absorption. Human colonic cell line Caco-2 cells were treated with high temperature (37 t...

journal_title：Digestive diseases and sciences

authors： Yang PC,Wang CS

更新日期：2006-05-01 00:00:00

abstract：:The question of whether alcohol drinking is a risk factor for fatty liver as shown by ultrasonography was investigated by both cross-sectional and longitudinal approaches in Japanese undergoing a health checkup. In this cross-sectional study, 32,438 males (49.0 +/- 11.9 years old) and 31,009 females (48.2 +/- 11.6 yea...

journal_title：Digestive diseases and sciences

authors： Yamada T,Fukatsu M,Suzuki S,Yoshida T,Tokudome S,Joh T

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Previous studies have shown that healing in intestinal wounds is proportionally faster than skin. Cytokines and growth factors play a major role in these coordinated wound-healing events. We hypothesized that this more rapid intestinal healing is due to an early upregulation of proinflammatory cytokines (IL-...

journal_title：Digestive diseases and sciences

authors： Zubaidi A,Buie WD,Hart DA,Sigalet D

更新日期：2010-06-01 00:00:00

abstract：:In recent years, three-dimensional (3-D) printing technology has become a standard tool that is used in several medical applications such as education, surgical training simulation and planning, and doctor-patient communication. Although liver surgery is ideally complemented by the use of preoperative 3-D-printed mode...

journal_title：Digestive diseases and sciences

authors： Larghi Laureiro Z,Novelli S,Lai Q,Mennini G,D'andrea V,Gaudenzi P,Marinozzi F,Engelmann C,Mookarje R,Raptis D,Rossi M,Jalan R

更新日期：2020-08-01 00:00:00

abstract：:Vitamin D deficiency is frequently observed in patients with Crohn's disease and may be associated with an increased risk of development of metabolic bone disease. To estimate the incidence of metabolic bone disease by noninvasive methods, 31 patients (17-75 years old) with Crohn's disease and low 25-hydroxyvitamin D ...

journal_title：Digestive diseases and sciences

authors： Vogelsang H,Ferenci P,Woloszczuk W,Resch H,Herold C,Frotz S,Gangl A

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:The renin-angiotensin system (RAS) is activated in inflammatory bowel disease (IBD), and vitamin D deficiency aggravates the development of colitis, but the relationship between the local colonic RAS and vitamin D is unclear with regard to the pathogenesis of IBD. AIMS:To investigate whether vitamin D suppr...

journal_title：Digestive diseases and sciences

authors： Wei X,Li X,Du J,Ge X,Sun Y,Li X,Xun Z,Liu W,Wang ZY,Li YC

更新日期：2021-01-12 00:00:00

abstract：:The potential effect of recombinant human interleukin-11 (rhIL-11) on trinitrobenzene sulfonic acid (TNB)-induced colitis was investigated in rats. Intrarectal TNB (40 mg in 0.25 ml 40% ethanol) produced significant ulcerative colitis. The lesions were most severe at three days after TNB instillation, and then decline...

journal_title：Digestive diseases and sciences

authors： Qiu BS,Pfeiffer CJ,Keith JC Jr

更新日期：1996-08-01 00:00:00