Abstract:
BACKGROUND:Different factors have been associated with prolonged fluoroscopy time (FT) during endoscopic retrograde cholangiopancreatography (ERCP). AIM:We hypothesize that FT depends on both the anatomical location of the pathology managed during ERCP and the complexity of the ERCP. METHODS:Three centers participated in a retrospective multi-center cohort study. Data on patient demographics, ERCP complexity, and the location of pathology were collected. The relationships between FT and the location of pathology, ERCP complexity, patient demographics, and ERCP maneuvers, respectively, were analyzed. Prolonged FT was defined as a FT > 10 min. RESULTS:A total of 442 cases underwent ERCP in three different centers (301 cases, 76 cases, and 65 cases in centers A, B, and C, respectively) by six endoscopists. The median FT for all cases was 282 (range 8-3,516) s. Mean FT increased progressively according to anatomical location in the order extrahepatic cases {n = 298; mean FT 292 [95 % confidence interval (CI) 263-322] s}, pancreatic cases [n = 27; mean FT 359 (95 % CI 200-517) s], and intrahepatic cases [n = 117; mean FT 736 s (95 % CI 635-836) s]. Mean FT increased progressively with the complexity scale, with mean FT for Grade I, 218 (95 % CI 138-299) s; Grade II, 295 (95 % 261-329) s; Grade III, 586 (95 % CI 508-663) s; Grade IV, 636 (95 % CI 437-834) s. Multivariable analysis confirmed that prolonged FT was independently associated with anatomical location of the targeted pathology during ERCP-but not with ERCP complexity and endoscopy center. CONCLUSION:Prolonged FT during ERCP is associated most strongly with intrahepatic cases. FT can be used most effectively as a quality measure if it is stratified according to presence or absence of intrahepatic cases.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Alkhatib AA,Abdel Jalil AA,Faigel DO,Pannala R,Crowell M,Harrison MEdoi
10.1007/s10620-014-3508-5subject
Has Abstractpub_date
2015-06-01 00:00:00pages
1787-92issue
6eissn
0163-2116issn
1573-2568journal_volume
60pub_type
杂志文章,多中心研究abstract::Segments of rat ileum and colon were infused in vivo to test if 0.1 M lactate, 10(-4) M H+, or both altered mucosal structure and function. In the first series of experiments, lactate concentration was kept at 0.1 M while H+ was varied from 10(-4) to 10(-7) M. Lactate and 10(-4) M H+ in the colon, and lactate and 10(-...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01308119
更新日期:1982-01-01 00:00:00
abstract:BACKGROUND:As several factors can contribute to low bone mineral density (BMD), we investigated the role of vitamin D in low BMD while controlling for other risk factors in inflammatory bowel diseases (IBD) patients. METHODS:We conducted a prospective cross-sectional study between 2008 and 2012 in adult IBD patients. ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
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abstract::To investigate the possible role of pepsin in ulceration induced by hydrogen ion back-diffusion, the ratio of alkali-labile pepsinogen to total pepsinogen was studied during the course of aspirin- and taurocholate-induced gastric ulceration in comparison with the changes in the ion permeability and histological findin...
journal_title:Digestive diseases and sciences
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journal_title:Digestive diseases and sciences
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更新日期:1996-10-01 00:00:00
abstract::Heart failure is a recognized, although uncommon, cause of massive liver cell necrosis, the clinical consequences of which are intermingled with those of cardiac insufficiency in most cases. We report the cases of six patients suffering from chronic heart failure in whom an episode of acute circulatory failure resulte...
journal_title:Digestive diseases and sciences
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doi:10.1007/BF01312732
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abstract::Patients with gallstone disease have impaired gallbladder motility. Prostaglandins are thought to be important mediators of gallbladder hypomotility. We assessed the effect of aspirin, a prostaglandin inhibitor on gallbladder resting volume and ejection fraction according to a double-blind study protocol in 20 healthy...
journal_title:Digestive diseases and sciences
pub_type: 临床试验,杂志文章,随机对照试验
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abstract::Data on performance characteristics of flexible sigmoidoscopy (FS) between age groups are limited. This study evaluates screening FS in subjects > or = 75 years of age (elderly) compared with ages 50-74 years (general screening population). Data were collected on patient characteristics, insertion depth, procedural di...
journal_title:Digestive diseases and sciences
pub_type: 临床试验,杂志文章
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journal_title:Digestive diseases and sciences
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abstract::We present six cases of cancer associated with Crohn's disease and stress the importance of the earlier age of onset than spontaneously arising small-bowel carcinoma, the long period of latency from the time of diagnosis of Crohn's disease to that of carcinoma, and the generally poor prognosis. We emphasize, furthermo...
journal_title:Digestive diseases and sciences
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更新日期:1980-12-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章,评审
doi:
更新日期:1998-09-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
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更新日期:1995-07-01 00:00:00
abstract::Nonalcoholic fatty liver disease (NAFLD) is widely considered to be the hepatic manifestation of the metabolic syndrome and is closely linked to dyslipidemia, obesity, and insulin resistance. Patients with NAFLD have increased mortality when compared to the general population, primarily related to cardiovascular disea...
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1026687022202
更新日期:1999-12-01 00:00:00
abstract::To study the efficacy of standard blood tests of liver function (LFTs) and technetium-99m liver scan followed by laparoscopy in the diagnosis of solid malignant tumors of the liver, 100 consecutive patients were evaluated who had these tests because of clinical suspicion of liver neoplasm. Malignant liver tumors were ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
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更新日期:1979-08-01 00:00:00
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journal_title:Digestive diseases and sciences
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pub_type: 临床试验,杂志文章
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journal_title:Digestive diseases and sciences
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journal_title:Digestive diseases and sciences
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journal_title:Digestive diseases and sciences
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journal_title:Digestive diseases and sciences
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2006-05-01 00:00:00