Colorectal Cancer Screening in Inflammatory Bowel Disease.

Abstract:

:Patients with long-standing ulcerative colitis (UC) or Crohn's colitis are at increased risk of developing colorectal cancer (CRC). Given that most cases of CRC are thought to arise from dysplasia, previous guidelines have recommended endoscopic surveillance with random biopsies obtained from all segments of the colon involved by endoscopic or microscopic inflammation. However, recent evidence has suggested that the majority of dysplastic lesions in patients with inflammatory disease (IBD) are visible, and data have been supportive of chromoendoscopy with targeted biopsies of visible lesions versus traditional random biopsies. This review article will discuss the risk of colon cancer in patients with IBD, as well as current recommendations for CRC screening and surveillance in patients with UC or Crohn's colitis.

journal_name

Dig Dis Sci

authors

Sengupta N,Yee E,Feuerstein JD

doi

10.1007/s10620-015-3979-z

subject

Has Abstract

pub_date

2016-04-01 00:00:00

pages

980-9

issue

4

eissn

0163-2116

issn

1573-2568

pii

10.1007/s10620-015-3979-z

journal_volume

61

pub_type

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