MiR-325 Promotes Oxaliplatin-Induced Cytotoxicity Against Colorectal Cancer Through the HSPA12B/PI3K/AKT/Bcl-2 Pathway.

abstract：BACKGROUND:Safety-net hospitals are enriched in ethnic minorities and provide opportunities for high-impact hepatitis B virus (HBV) screening. AIM:We aim to evaluate the impact of a pilot program integrating HBV screening into outpatient endoscopy among urban safety-net populations. METHODS:From July 2015 to May 2017...

journal_title：Digestive diseases and sciences

authors： Campbell B,Lopez A,Liu B,Bhuket T,Wong RJ

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND AND AIMS:Fatigue significantly impacts the quality of life of patients with inflammatory bowel disease (IBD). This study aimed to assess the effect of a personalized, intensive exercise program on fatigue, health-related quality of life (HRQoL), and cardiorespiratory fitness in patients with quiescent IBD an...

journal_title：Digestive diseases and sciences

authors： van Erp LW,Roosenboom B,Komdeur P,Dijkstra-Heida W,Wisse J,Horjus Talabur Horje CS,Liem CS,van Cingel REH,Wahab PJ,Groenen MJM

更新日期：2020-04-01 00:00:00

abstract：:This study determined the effect of low-frequency and high-frequency gastric electrical stimulation (GES) on canine lower esophageal sphincter (LES) pressure and also evaluated the effect of such stimulation on neurohumoral factors that modulate LES pressure. Eight dogs were fitted with stimulation wires along the gre...

journal_title：Digestive diseases and sciences

authors： Xing J,Felsher J,Brody F,Soffer E

更新日期：2005-08-01 00:00:00

abstract：:Ascites is more difficult to detect when only a small quantity is present. The aim of this pilot study was to determine the optimal bowel sound characteristics in order to distinguish no ascites from small-volume ascites by advanced processing of bowel sound wave patterns. This analysis results in the definition of th...

journal_title：Digestive diseases and sciences

authors： Liatsos C,Hadjileontiadis LJ,Mavrogiannis C,Patch D,Panas SM,Burroughs AK

更新日期：2003-08-01 00:00:00

abstract：:Depletion of granulocytes and monocytes (GM) by selective apheresis (GMA) with an Adacolumn exerts an anti-inflammatory effect in patients with ulcerative colitis (UC) or rheumatoid arthritis. However, the mechanism of the anti-inflammatory effect of GMA is not fully understood yet. We investigated the effect of GMA o...

journal_title：Digestive diseases and sciences

authors： Sakimura K,Omori T,Iwashita E,Yoshida T,Tsuzuki Y,Fujimori K,Konishi F,Yoshida Y,Anzai H,Suzuki H,Sugawara S,Takeda Y,Hiraishi K,Saniabadi AR,Ide T,Miura S,Ota S

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Evidence of humanistic detriments of Clostridium difficile infection (CDI) remains limited. AIMS:To assess humanistic burden associated with CDI. METHODS:Self-reported National Health and Wellness Survey data between 2013 and 2016 were analyzed for the USA, five European countries, China, and Brazil. Outco...

journal_title：Digestive diseases and sciences

authors： Heinrich K,Harnett J,Vietri J,Chambers R,Yu H,Zilberberg M

更新日期：2018-11-01 00:00:00

abstract：:Inflammatory bowel disease (IBD) is an important etiologic factor in the development of colorectal cancer (CRC). The risk of CRC begins to increase 8 or 10 years after the diagnosis of IBD. This type of cancer is called colitis-associated CRC (CA-CRC). The molecular pathogenesis of inflammatory epithelium might play a...

journal_title：Digestive diseases and sciences

authors： Yashiro M

更新日期：2015-08-01 00:00:00

abstract：:The role of mast cells, potential mediators of mucosal immunity and inflammation, was studied morphologically in the rectal mucosa in two acute diarrheal diseases, cholera and shigellosis. Quantitation of mucosal mast cells showed that they were significantly higher in the deeper lamina propria where blood vessels and...

journal_title：Digestive diseases and sciences

authors： Pulimood AB,Mathan MM,Mathan VI

更新日期：1998-09-01 00:00:00

abstract：:Concordance between gram-negative enteric and other toxin-producing bacteria in blood and stool culture, endotoxin (lipopolysaccharide), and interleukin-6 (IL-6) was measured in 60 preterm infants (600-1600 g) as a clinical index in neonatal necrotizing enterocolitis (NEC). E. coli, Klebsiella, Enterobacter, and Clost...

journal_title：Digestive diseases and sciences

authors： Duffy LC,Zielezny MA,Carrion V,Griffiths E,Dryja D,Hilty M,Rook C,Morin F 3rd

更新日期：1997-02-01 00:00:00

abstract：:The prevalence of lymphocytic gastritis, a specific form of chronic gastritis characterized by infiltration of gastric superficial epithelium with T lymphocytes, has been established in nonulcer dyspepsia. Among a population sample of 586 patients at risk for gastric carcinoma, 0.83% of patients with nonulcer dyspepsi...

journal_title：Digestive diseases and sciences

authors： Jaskiewicz K,Price SK,Zak J,Louwrens HD

更新日期：1991-08-01 00:00:00

abstract：:Minimal lesions of the small bowel are mucosal changes characterized by an increased number of intraepithelial lymphocytes (with or without crypt hyperplasia) and normal villous architecture. Such changes are associated with a wide spectrum of conditions, ranging from food intolerances to infections, and from drugs to...

journal_title：Digestive diseases and sciences

authors： Volta U,Caio G,Ghirardi C,Lungaro L,Mansueto P,Carroccio A,De Giorgio R

更新日期：2020-10-01 00:00:00

abstract：:Gas within the stomach wall is a rare occurrence. A case of intramural gas is presented. When air or gas is seen within the gastric wall on x-ray, gastric emphysema, emphysematous gastritis, or pneumatosis intestinalis is diagnosed. These classifications have become vague and contradictory. Gas in the gastric wall can...

journal_title：Digestive diseases and sciences

authors： Kussin SZ,Henry C,Navarro C,Stenson W,Clain DJ

更新日期：1982-10-01 00:00:00

abstract：:We examined the effect of sildenafil, an inhibitor of phosphodiesterase subtype 5, that catalyzes hydrolysis of 3',5'-cyclic guanosine monophosphate (cGMP), on indomethacin-induced small-intestinal ulceration in rats and investigated the mechanism of this action, especially in relation to endogenous nitric oxide (NO)....

journal_title：Digestive diseases and sciences

authors： Kato N,Mashita Y,Kato S,Mitsufuji S,Yoshikawa T,Takeuchi K

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Diagnosis of eosinophilic esophagitis (EoE) requires quantification of esophageal eosinophilia. AIMS:The aims of this study were to assess inter- and intraobserver reliability for measuring esophageal eosinophil counts and to validate a novel method of determining tissue eosinophil density using digitized h...

journal_title：Digestive diseases and sciences

authors： Dellon ES,Fritchie KJ,Rubinas TC,Woosley JT,Shaheen NJ

更新日期：2010-07-01 00:00:00

abstract：:A comparative study of three different high-dose regimens of interferon-alpha-2b (IFN) was conducted in patients with chronic hepatitis C to determine which was better at obtaining a sustained remission. A total of 126 patients were assigned randomly to one of three groups: group A was given 10 million international u...

journal_title：Digestive diseases and sciences

authors： Iino S,Hino K,Kuroki T,Suzuki H,Yamamoto S

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:Computed tomography (CT) and magnetic resonance (MR) enterography are now widely used to diagnose and monitor Crohn's disease. AIM:We sought to assess the use of enterography for management of inflammatory bowel disease (IBD) in our medical center. METHODS:We performed a retrospective review of all patient...

journal_title：Digestive diseases and sciences

authors： Patel NS,Pola S,Muralimohan R,Zou GY,Santillan C,Patel D,Levesque BG,Sandborn WJ

更新日期：2014-04-01 00:00:00

abstract：:Low or minimal doses of aspirin are widely used for prevention of cardiovascular diseases. Aspirin is known to produce severe adverse gastrointestinal effects, such as bleeding and perforation. Less is known about the risk associated with minidose aspirin. Our aim was to assess the possible association of upper gastro...

journal_title：Digestive diseases and sciences

authors： Sapoznikov B,Vilkin A,Hershkovici M,Fishman M,Eliakim R,Niv Y

更新日期：2005-09-01 00:00:00

abstract：:Our aim was to investigate the role of renal colic, a clinical condition characterized by excruciating pain, in the etiopathogenesis of irritable bowel syndrome (IBS). Two groups of patients were enrolled in the study. Group I consisted of 59 patients (33 male and 26 female) with a median age of 41.9 (18 to 58) years....

journal_title：Digestive diseases and sciences

authors： Erdem E,Akbay E,Sezgin O,Doruk E,Canpolat B,Cayan S

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:The risk of pancreatic cancer is elevated among people with new-onset diabetes (NOD). Based on Rochester Epidemiology Project Data, the Enriching New-Onset Diabetes for Pancreatic Cancer (END-PAC) model was developed and validated. AIMS:We validated the END-PAC model in a cohort of patients with NOD using r...

journal_title：Digestive diseases and sciences

authors： Chen W,Butler RK,Lustigova E,Chari ST,Wu BU

更新日期：2021-01-01 00:00:00

abstract：INTRODUCTION:Crohn's disease (CD) and ulcerative colitis (UC) are associated with considerable direct healthcare costs. There have been few comprehensive analyses of all IBD- and non-IBD comorbidities that determine direct costs in this population. METHODS:We used data from a validated cohort of patients with inflamma...

journal_title：Digestive diseases and sciences

authors： Cai W,Cagan A,He Z,Ananthakrishnan AN

更新日期：2020-05-20 00:00:00

abstract：BACKGROUND:A role of an altered dietary pattern (e.g., a diet rich in sugar) but also alterations at the level of the intestinal barrier have repeatedly been discussed to be involved in the development and progression of nonalcoholic fatty liver disease (NAFLD). AIMS:To determine if the nutritional intake, intestinal ...

journal_title：Digestive diseases and sciences

authors： Volynets V,Küper MA,Strahl S,Maier IB,Spruss A,Wagnerberger S,Königsrainer A,Bischoff SC,Bergheim I

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:The pathogenesis and treatment of ulcerative colitis remain poorly understood. The aim of the present study is to investigate the effects of black cumin (Nigella sativa) oil on rats with colitis. METHODS:Experimental colitis was induced with 1 mL trinitrobenzene sulfonic acid (TNBS) in 40% ethanol by intrac...

journal_title：Digestive diseases and sciences

authors： Isik F,Tunali Akbay T,Yarat A,Genc Z,Pisiriciler R,Caliskan-Ak E,Cetinel S,Altıntas A,Sener G

更新日期：2011-03-01 00:00:00

abstract：:Response to interferon (IFN) therapy for chronic hepatitis C has been determined by the alteration of serum alanine aminotransferase (ALT) values. However, eradication of hepatitis C virus (HCV) could be another aim of the therapy. Thus, we serially measured serum HCV RNA levels during therapy and for at least 12 mont...

journal_title：Digestive diseases and sciences

authors： Aiyama T,Yoshioka K,Hirofuji H,Kusakabe A,Yamada M,Tanaka K,Kakumu S

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Despite accumulating data on the pathogenesis of eosinophilic esophagitis, not much is known about risk factors for the development of the disease. The role of factors such as smoking, breastfeeding, early antibiotic exposure and other factors that have been associated with other allergic diseases has not be...

journal_title：Digestive diseases and sciences

authors： Slae M,Persad R,Leung AJ,Gabr R,Brocks D,Huynh HQ

更新日期：2015-11-01 00:00:00

abstract：:Morin, a plant-derived flavonoid, has been reported to exhibit a wide range of pharmacological properties. In this study, we investigated the protective effect of morin on hepatic fibrosis induced by dimethylnitrosamine (DMN) in rats. Oral administration of morin remarkably prevented weight loss in the body and liver ...

journal_title：Digestive diseases and sciences

authors： Lee HS,Jung KH,Park IS,Kwon SW,Lee DH,Hong SS

更新日期：2009-04-01 00:00:00

abstract：:Choledochoduodenostomy may be followed by the "sump syndrome." This previously required surgical intervention. We describe the successful application of endoscopic therapy in two patients with this syndrome. ...

journal_title：Digestive diseases and sciences

authors： Barkin JS,Silvis S,Greenwald R

更新日期：1980-08-01 00:00:00

abstract：:Methionine (Meth) is an essential amino acid involved in DNA methylation and glutathione biosynthesis. We examined the effect of Meth on the development of steatohepatitis. Rats were fed (five weeks) amino acid-based Meth-choline-sufficient (A-MCS) or total deficient (MCD) diets and gavaged daily (two weeks) with vehi...

journal_title：Digestive diseases and sciences

authors： Oz HS,Chen TS,Neuman M

更新日期：2008-03-01 00:00:00

abstract：:The 1993 Milwaukee Cryptosporidium outbreak posed several questions regarding appropriate management and prognosis of inflammatory bowel disease patients acutely infected with this organism. We prospectively identified and monitored 12 patients with stable ulcerative colitis or Crohn's disease who suffered abrupt clin...

journal_title：Digestive diseases and sciences

authors： Manthey MW,Ross AB,Soergel KH

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Percutaneous gastrostomy (PEG) is a common inpatient procedure. Prior data from National Inpatient Sample (NIS) in 2006 reported a mortality rate of 10.8% and recommended more careful selection of PEG candidates. This study assessed for improvement in the last 10 years in mortality rate and complica...

journal_title：Digestive diseases and sciences

authors： Stein DJ,Moore MB,Hoffman G,Feuerstein JD

更新日期：2020-06-19 00:00:00

abstract：BACKGROUND:In search for a source of gastrointestinal bleeding, endoscopy frequently reveals mucosal lesions of questionable dignity. AIM:To investigate the probability of ascertaining conclusive evidence for gastrointestinal bleeding from a suspicious mucosal lesion through a single or multiple consecutive endoscopie...

journal_title：Digestive diseases and sciences

authors： Sonnenberg A

更新日期：2013-05-01 00:00:00