Vitamin C Improves Gastroparesis in Diabetic Rats: Effects on Gastric Contractile Responses and Oxidative Stress.

abstract：:Because of marked improvement in diagnosis and management, cystic fibrosis is now more frequently noted in young adults, many of whom have only mild clinical forms. Pancreatitis is a known complication of cystic fibrosis and may occur at any time in the course of the disease; in rare instances, pancreatitis is the fir...

journal_title：Digestive diseases and sciences

authors： Masaryk TJ,Achkar E

更新日期：1983-10-01 00:00:00

abstract：BACKGROUND AND STUDY AIMS:Bowel-cleansing studies are frequently underpowered, poorly designed, and with subjective assessments. Consensus on tolerability of the bowel-cleansing agents is thus lacking. This study developed and validated a bowel-preparation tolerability questionnaire and used it to assess the tolerabili...

journal_title：Digestive diseases and sciences

authors： Lawrance IC,Willert RP,Murray K

更新日期：2013-04-01 00:00:00

abstract：:A comparative study of three different high-dose regimens of interferon-alpha-2b (IFN) was conducted in patients with chronic hepatitis C to determine which was better at obtaining a sustained remission. A total of 126 patients were assigned randomly to one of three groups: group A was given 10 million international u...

journal_title：Digestive diseases and sciences

authors： Iino S,Hino K,Kuroki T,Suzuki H,Yamamoto S

更新日期：1993-04-01 00:00:00

abstract：BACKGROUND:MicroRNA is essential for the malignant progression of human gastric cancer (GC), which is a leading cause of cancer deaths. However, the mechanism is still not so clear. AIMS:In our present research, we investigated the effect of miR-9-5p in GC. METHODS:We detected miR-9-5p expression in human gastric epi...

journal_title：Digestive diseases and sciences

authors： Fan Y,Shi Y,Lin Z,Huang X,Li J,Huang W,Shen D,Zhuang G,Liu W

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:The preferred method for screening asymptomatic people for colorectal cancer (CRC) is colonoscopy, according to the new American guidelines. The aim of our study was to perform a meta-analysis of the prospective cohorts using total colonoscopy for screening this population for CRC. We looked for the diagnosti...

journal_title：Digestive diseases and sciences

authors： Niv Y,Hazazi R,Levi Z,Fraser G

更新日期：2008-12-01 00:00:00

abstract：:Ehlers-Danlos syndrome (EDS) type IV is an autosomal dominant connective tissue disease caused by mutations in the type III collagen gene resulting in extreme tissue fragility. Affected individuals are at risk of dramatic and often fatal complications, mostly spontaneous arterial, uterine, or colonic ruptures. Phenoty...

journal_title：Digestive diseases and sciences

authors： Gelbmann CM,Köllinger M,Gmeinwieser J,Leser HG,Holstege A,Schölmerich J

更新日期：1997-08-01 00:00:00

abstract：:The incidence of colorectal adenocarcinoma increased in the five major ethnic groups in Hawaii, but more in men than women. The highest rates were in the Chinese and Japanese. The site-specific time trend patterns revealed that the greatest increase occurred in rectosigmoid cancer, followed by cancer of the sigmoid co...

journal_title：Digestive diseases and sciences

authors： Nomura AM,Kolonel LN,Hinds MW

更新日期：1981-12-01 00:00:00

abstract：:Somatostatin inhibits colonic ion secretion in animal models and cultured intestinal cell lines via somatostatin receptor subtype 2 and subtype 1, respectively. In a recent in vitro ion transport study of the human colon, somatostatin was shown to stimulate short-circuit current, a measure of electrogenic ion transpor...

journal_title：Digestive diseases and sciences

authors： Hope N,Butt G,Ross I,Warhurst G,Arn M,Grigor M,Lubcke R,Barbezat GO

更新日期：2001-11-01 00:00:00

abstract：:Metoclopramide tablets have been approved for use in the acute and chronic management of diabetic gastroparesis. Its efficacy as an antiemetic has been well documented. We measured the acute and chronic effects of oral metoclopramide on gastric liquid emptying in 12 diabetic patients with symptoms of stasis using scin...

journal_title：Digestive diseases and sciences

authors： Schade RR,Dugas MC,Lhotsky DM,Gavaler JS,Van Thiel DH

更新日期：1985-01-01 00:00:00

abstract：:To date, tests of small intestinal passive permeability have involved the ingestion of test molecules whose permeation is assessed indirectly by measuring their urinary recovery. Excretion ratios of marker molecules (eg, lactulose-to-mannitol excretion ratio, LMER) are useful clinically. Measurement of permeability ma...

journal_title：Digestive diseases and sciences

authors： Cox MA,Lewis KO,Cooper BT

更新日期：1999-02-01 00:00:00

abstract：:Gastrointestinal motor dysfunction persists in a large number of children subjected to surgical treatment for Hirschsprung's disease, indicating abnormalities in the remaining intestine. The aim of the study was to detect possible alterations in frequency and topographic distribution of enteric neurons and interstitia...

journal_title：Digestive diseases and sciences

authors： Sandgren K,Larsson LT,Ekblad E

更新日期：2002-05-01 00:00:00

abstract：:Serum levels of immunosuppressive acidic protein (IAP) were determined in 68 patients undergoing resection of colorectal cancer and 21 healthy subjects. Eighteen patients had perioperative transfusion of allogeneic blood (transfused patients) and 50 patients had no blood transfusion (nontransfused patients). Transfuse...

journal_title：Digestive diseases and sciences

authors： Iwanaga T,Suzuki H

更新日期：1999-08-01 00:00:00

abstract：:We studied the natural history of ulcerative colitis (UC) by following 1116 patients in whom UC had been diagnosed or confirmed at The Cleveland Clinic Foundation between 1960 and 1983. Data before 1973 were obtained retrospectively. Criteria for inclusion in the study were: a diagnosis of UC confirmed by clinical, ra...

journal_title：Digestive diseases and sciences

authors： Farmer RG,Easley KA,Rankin GB

更新日期：1993-06-01 00:00:00

abstract：:Liver transplantation is the only effective treatment of familial amyloidotic polyneuropathy type I (FAP). The aim of the present investigation was to identify factors at the time of submission for transplantation that had impact on survival, with special reference to gastrointestinal disturbances. All 28 liver-transp...

journal_title：Digestive diseases and sciences

authors： Suhr O,Danielsson A,Rydh A,Nyhlin N,Hietala SO,Steen L

更新日期：1996-10-01 00:00:00

abstract：:The intestine-specific caudal-related homeobox transcription factor Cdx2 is widely accepted to play a key role in intestinal development and differentiation in mammals. We studied the role of Cdx2 in the development of Barrett's esophagus (BE). In previous studies, we have shown a sequence of morphological changes of ...

journal_title：Digestive diseases and sciences

authors： Tatsuta T,Mukaisho K,Sugihara H,Miwa K,Tani T,Hattori T

更新日期：2005-03-01 00:00:00

abstract：:In vitro and in vivo experiments were carried out with medium-chain glycerides. In vitro, cholesterol gallstones were rapidly dissolved by medium-chain glycerides; control experiments with saline solution failed to modify the size of the stones. In vivo, medium-chain glycerides were instilled through an intraductal tu...

journal_title：Digestive diseases and sciences

authors： Uribe M,Uscanga L,Farca S,Sanjurjo JL,LaGarriga J,Ortíz JH

更新日期：1981-07-01 00:00:00

abstract：:Sodium butyrate is a well-recognized differentiating agent inducing alkaline phosphatase activity, one of the epithelial differentiation markers. When IEC6 cells, a nontransformed, small intestinal epithelial cell line, were cultured with butyrate, this substrate induced alkaline phosphate activity in a time- and dose...

journal_title：Digestive diseases and sciences

authors： Fukushima K,Sasaki I,Hasegawa H,Takahashi K,Naito H,Funayama Y,Matsuno S

更新日期：1998-05-01 00:00:00

abstract：:Alterations in insulin and glucagon levels might account for the plasma amino acid imbalance of cirrhotics. In order to verify this hypothesis we evaluated basal insulin, glucagon, branched-chain amino acids, aromatic amino acids, and free tryptophan in 13 controls and 37 cirrhotics divided on the basis of their menta...

journal_title：Digestive diseases and sciences

authors： Marchesini G,Forlani G,Zoli M,Angiolini A,Scolari MP,Bianchi FB,Pisi E

更新日期：1979-08-01 00:00:00

abstract：:Low or minimal doses of aspirin are widely used for prevention of cardiovascular diseases. Aspirin is known to produce severe adverse gastrointestinal effects, such as bleeding and perforation. Less is known about the risk associated with minidose aspirin. Our aim was to assess the possible association of upper gastro...

journal_title：Digestive diseases and sciences

authors： Sapoznikov B,Vilkin A,Hershkovici M,Fishman M,Eliakim R,Niv Y

更新日期：2005-09-01 00:00:00

abstract：:The diagnostic values in detecting terminal ileum dysfunction using [75Se]HCAT have been assessed for two different scintigraphic techniques in 58 subjects. The measurement of [75Se]HCAT T1/2 in the enterohepatic circulation by daily gallbladder scintigraphy showed 78% sensitivity, 96% specificity, 96% positive predic...

journal_title：Digestive diseases and sciences

authors： Ferraris R,Galatola G,Barlotta A,Pellerito R,Fracchia M,Cottino F,de la Pierre M

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:Gastrointestinal motility disorder is an important pathological basis for functional dyspepsia (FD). Epigastric ache and discomfort are the main symptoms of FD, and ghrelin deficiency is closely related to the occurrence and development of FD. While electroacupuncture (EA) alleviated the symptoms of FD patie...

journal_title：Digestive diseases and sciences

authors： Tang L,Zeng Y,Li L,Wang J,Peng D,Zhang T,Zhang H,An X

更新日期：2020-06-01 00:00:00

abstract：:Our aim was to investigate whether there are changes in permeability to sucrose in asymptomatic Helicobacter pylori gastritis. Nineteen asymptomatic subjects with Helicobacter pylori-associated gastritis with no or mild mucosal atrophy and 19 age- and sex-matched normal controls were studied by peroral load of sucrose...

journal_title：Digestive diseases and sciences

authors： Borch K,Sjöstedt C,Hannestad U,Söderholm JD,Franzén L,Mårdh S

更新日期：1998-04-01 00:00:00

abstract：:Our objective was to study the predictive value of the family history in the initial diagnosis of hereditary hemochromatosis. Sixty five hemochromatosis proband patients and 66 control patients with chronic liver disease were assessed for a family history of hemochromatosis, cirrhosis, diabetes, and arthritis. There w...

journal_title：Digestive diseases and sciences

authors： Assy N,Adams PC

更新日期：1997-06-01 00:00:00

abstract：:Response to interferon (IFN) therapy for chronic hepatitis C has been determined by the alteration of serum alanine aminotransferase (ALT) values. However, eradication of hepatitis C virus (HCV) could be another aim of the therapy. Thus, we serially measured serum HCV RNA levels during therapy and for at least 12 mont...

journal_title：Digestive diseases and sciences

authors： Aiyama T,Yoshioka K,Hirofuji H,Kusakabe A,Yamada M,Tanaka K,Kakumu S

更新日期：1994-10-01 00:00:00

abstract：:Consumption of high-fiber diets has been recommended prior to fecal blood testing to increase bleeding from polyps, cancer, and other lesions associated with mucosal erosion in the gastrointestinal tract. The effect of a high-fiber diet on fecal hemoglobin loss was examined in 17 healthy subjects during two dietary pe...

journal_title：Digestive diseases and sciences

authors： Slavin JL,Melcher EA,Sundeen M,Schwartz S

更新日期：1991-07-01 00:00:00

abstract：:Bleeding from esophagogastric varices is a potentially deadly complication in patients with hepatosplenic schistosomiasis. The aim of this study is to establish indicators of variceal bleeding. We studied 40 patients with compensated hepatosplenic schistosomiasis and varices, analyzing four endoscopic (variceal size, ...

journal_title：Digestive diseases and sciences

authors： Martins RD,Szejnfeld J,Lima FG,Ferrari AP

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:A new prepared oral viscous budesonide (PVB) has been effective in inducing clinical and histological remission in pediatric eosinophilic esophagitis (EoE). AIMS:To evaluate the efficacy of a 12-week maintenance therapy on clinical, endoscopic, and histological remission using half of the dose used in the i...

journal_title：Digestive diseases and sciences

authors： Oliva S,Rossetti D,Papoff P,Tiberti A,Mallardo S,Volpe D,Ruggiero C,Russo G,Vezzoli D,Isoldi S,Cucchiara S

更新日期：2019-06-01 00:00:00

abstract：:To evaluate the frequency and type of gastroduodenal mucosal inflammatory changes in patients with symptomatic acid peptic disease and nonulcer dyspepsia, 100 patients with gastrointestinal symptoms indicative of acid peptic disease or dyspepsia and 10 control subjects were clinically evaluated and underwent radiograp...

journal_title：Digestive diseases and sciences

authors： Greenlaw R,Sheahan DG,DeLuca V,Miller D,Myerson D,Myerson P

更新日期：1980-09-01 00:00:00

abstract：BACKGROUND AND AIMS:The nature and outcomes of infection among patients with cirrhosis in safety-net hospitals are not well described. We aimed to characterize the rate of and risk factors for infection, both present on admission and nosocomial, in this unique population. We hypothesized that infections would be associ...

journal_title：Digestive diseases and sciences

authors： Fricker ZP,Mukthinuthalapati VVPK,Akinyeye S,Chalasani N,Attar BM,Balakrishnan M,Ghabril M,Long MT

更新日期：2021-01-01 00:00:00

abstract：:Extraintestinal symptoms are often found in patients with irritable bowel syndrome (IBS). Recent studies suggest that IBS is associated with bronchial hyperresponsiveness. But it is still arguable that the bronchial hyperresponsiveness is associated with IBS patients. The purpose of this study is to investigate the po...

journal_title：Digestive diseases and sciences

authors： Jun DW,Lee OY,Yoon HJ,Lee HL,Yoon BC,Choi HS,Lee MH,Lee DH,Kee CS

更新日期：2005-09-01 00:00:00