Abstract:
:Consumption of high-fiber diets has been recommended prior to fecal blood testing to increase bleeding from polyps, cancer, and other lesions associated with mucosal erosion in the gastrointestinal tract. The effect of a high-fiber diet on fecal hemoglobin loss was examined in 17 healthy subjects during two dietary periods: (1) self-selected diet, (2) same diet plus 24 g/day dietary fiber (Fiber One Cereal). Five-day fecal composites were weighed and homogenized, and hemoglobin concentration was determined by the HemoQuant test. Average daily fecal weight increased from 145 +/- 90 g to 281 +/- 91 g (P = 0.0001), fecal hemoglobin concentrations decreased from 0.98 +/- 0.48 to 0.48 +/- 0.28 mg/g (P = 0.0001), while daily fecal hemoglobin contents were similar (P = 0.39) for self-selected and added-fiber diets, respectively. In these healthy individuals, a high-fiber diet had no effect on mucosal bleeding, but the increased fecal weight significantly lowered fecal hemoglobin concentration. Clinical implications are considered.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Slavin JL,Melcher EA,Sundeen M,Schwartz Sdoi
10.1007/BF01297143subject
Has Abstractpub_date
1991-07-01 00:00:00pages
929-32issue
7eissn
0163-2116issn
1573-2568journal_volume
36pub_type
杂志文章abstract::The aim of this study was to determine whether the sensitivity of indium-111 (111In) scanning in the assessment of the activity and extent of Crohn's disease correlates with the severity of intestinal lesions as measured by the newly validated Crohn's disease endoscopic index of severity (CDEIS). Nineteen patients wit...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01303166
更新日期:1993-09-01 00:00:00
abstract::A 70-year-old woman with secretory diarrhea was studied with a novel technique of recording small intestinal myoelectrical activity which allowed us to obtain long, uninterrupted records of slow waves and spikes at eight or more different intestinal levels simultaneously. Typical migrating action potential complexes (...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01300207
更新日期:1987-10-01 00:00:00
abstract:BACKGROUND AND AIMS:Avoidance of gluten is critical for individuals with celiac disease (CD), but there is also concern that "extreme vigilance" to a strict gluten-free diet may increase symptoms such as anxiety and fatigue, and therefore, lower quality of life (QOL). We examined the associations of QOL with energy lev...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-018-4936-4
更新日期:2018-06-01 00:00:00
abstract::Orocecal transit time was determined by the lactulose hydrogen breath test in nine healthy volunteers after administration of placebo, loperamide (16 mg per os), and loperamide (16 mg per os) followed by oral naloxone at doses of 16 and 32 mg. The four tests were performed in double-blind conditions and in random sequ...
journal_title:Digestive diseases and sciences
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF01296704
更新日期:1987-08-01 00:00:00
abstract::We have developed an improved semiconductor recording probe for monitoring motility of the upper small intestine in humans. The probe consists of six ultraminiature silicon pressure sensors spaced 10 cm apart and encased in a flexible polyurethane sheath. The probe is small [2.67 mm (8F) diameter], is easily passed tr...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01308196
更新日期:1985-02-01 00:00:00
abstract:PURPOSE:In the field of colorectal cancer and adenoma, Kudo's classification of pit pattern with magnifying chromocolonoscopy using crystal violet (CV) staining is now accepted. Magnifying endoscopy using narrow band imaging has been used for the diagnosis of gastric carcinoma; the characteristic findings of microvascu...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-011-1638-6
更新日期:2011-09-01 00:00:00
abstract::Because of marked improvement in diagnosis and management, cystic fibrosis is now more frequently noted in young adults, many of whom have only mild clinical forms. Pancreatitis is a known complication of cystic fibrosis and may occur at any time in the course of the disease; in rare instances, pancreatitis is the fir...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01317036
更新日期:1983-10-01 00:00:00
abstract::The aims of this study were to select the patients with a potential for progression to hepatic failure due to lamivudine-resistant HBV and to standardize the treatment for patients with lamivudine-resistant HBV. Patients (n = 47) with reactivated hepatitis due to lamivudine-resistant HBV were classified into two group...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-008-0384-x
更新日期:2008-11-01 00:00:00
abstract::We have studied three patients with chronic HBV infection who had a superimposed bout of type A hepatitis. The patients recovered uneventfully without observing a change in their clinical course afterwards. In one patient we observed transient disappearance of DNA polymerase during type A hepatitis; we have postulated...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01312556
更新日期:1983-08-01 00:00:00
abstract::Breath methane was studied in 394 subjects. Among 152 controls, 50.0% produced methane--42.1% of males and 57.9% of females. One hundred sixteen patients with gastrointestinal diseases were studied. Among 32 with Crohn's disease, only 2 (6.1%) produced methane, as well as 16 of 51 ulcerative colitis patients (31.4%) a...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01297052
更新日期:1987-03-01 00:00:00
abstract::Our aim was to investigate whether there are changes in permeability to sucrose in asymptomatic Helicobacter pylori gastritis. Nineteen asymptomatic subjects with Helicobacter pylori-associated gastritis with no or mild mucosal atrophy and 19 age- and sex-matched normal controls were studied by peroral load of sucrose...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1018809913230
更新日期:1998-04-01 00:00:00
abstract::The gold standard for measuring gastric emptying is scintigraphy, either with digestible solids or liquids. Unfortunately, this method is expensive and of limited availability. An alternative could be to use radiopaque markers (ROMs). Our aim was to compare these two tests in healthy volunteers and in patients to see ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1026609808495
更新日期:1999-04-01 00:00:00
abstract::Intestinal injury 4-48 hr after cytotoxic therapy (etoposide phosphate, 100 mg/kg body weight [bw], intravenously [i.v.]) was studied in rats using ligated intestinal loops. Chromium-51 ethylenediaminetetraacetic acid ((51)Cr-EDTA) and rubidium-86 chloride ((86)RbCl) were deposited intraluminally to determine the exte...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-005-2926-9
更新日期:2005-09-01 00:00:00
abstract::Impairment of pancreatic microcirculation has often been advocated as one pathogenic mechanism in necrotizing pancreatitis. In contrast, data on pancreatic capillary perfusion in edematous pancreatitis are scarce. It was the aim of this experimental study to compare changes in pancreatic microcirculation in edematous ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF02087702
更新日期:1994-12-01 00:00:00
abstract::We report a case of dissecting aneurysm of the celiac axis and hepatic artery resulting in obstructive jaundice. The aneurysm was demonstrated both by ultrasound and by angiography, but the associated aortic dissection was apparent only on CT scan. The patient was treated with percutaneous transhepatic biliary drainag...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01296672
更新日期:1987-12-01 00:00:00
abstract:BACKGROUND:Much of the economic burden of Crohn's disease (CD) is related to surgery. Twenty percent of patients with CD have isolated colonic disease. While permanent end ileostomy (EI) is generally the procedure of choice for patients with refractory CD colitis, single-center experiences suggest that restorative proc...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-015-3886-3
更新日期:2016-02-01 00:00:00
abstract:BACKGROUND:Gastrointestinal motility disorder is an important pathological basis for functional dyspepsia (FD). Epigastric ache and discomfort are the main symptoms of FD, and ghrelin deficiency is closely related to the occurrence and development of FD. While electroacupuncture (EA) alleviated the symptoms of FD patie...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-019-05960-5
更新日期:2020-06-01 00:00:00
abstract:BACKGROUND:MELD attempts to objectively predict the risk of mortality of patients with liver cirrhosis and is commonly used to prioritize organ allocation. Despite the usefulness of the MELD, updated metrics could further improve the accuracy of estimates of survival. AIMS:To assess and compare the prognostic ability ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-018-5360-5
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:HAb18G/CD147 expression has been associated with many tumor invasion molecules, which play important roles in recurrence and poor differentiation of esophageal squamous cell carcinoma (ESCC). However, the clinical implications of HAb18G/CD147 in ESCC are still unclear. AIMS:In this study, we clarified the c...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-011-1812-x
更新日期:2011-12-01 00:00:00
abstract::The frequent association of stromal tumors with neurofobromatosis raises high suspicion of a possible correlation between the two entities. The aim of this study was to analyze clinicopathologic features of patients with concomitant neurofibromatosis and gastrointestinal stromal tumors and to discuss the molecular bas...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/b:ddas.0000037806.14471.a2
更新日期:2004-08-01 00:00:00
abstract:UNLABELLED:From studies in 43 patients (17 male, 26 female, mean age 51 years), we compared the analysis of the routine complete "24-hr" ambulatory esophageal pH monitoring study to that of the 16-hr overnight interval (4:00 PM to 8:00 AM). The latter included a major meal with an upright postprandial period and a recu...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01300383
更新日期:1992-06-01 00:00:00
abstract::We explored the function of the intestine's mucosal barrier to foreign antigen entry in Crohn's disease. Macroscopically and microscopically uninvolved areas of the small intestines of patients with Crohn's disease were examined. We studied 27 endoscopic biopsy samples from 17 patients with Crohn's disease and 14 samp...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF02088568
更新日期:1996-07-01 00:00:00
abstract::Gastroesophageal reflux disease (GERD) is caused by a mechanically defective lower esophageal sphincter (LES) and may be worsened by impaired esophageal peristalsis. The aim of this study was to evaluate the efficacy of medical treatment depending on the function of the LES and esophageal peristalsis. We studied 128 G...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1025434726161
更新日期:2003-09-01 00:00:00
abstract::Endoscopic injection sclerotherapy is known to cause a variety of motility abnormalities, but the correlation between these changes and symptomatology has not been clearly defined. To assess the effects of endoscopic sclerosis of varices on esophageal function and symptoms, we prospectively studied esophageal motility...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01318367
更新日期:1985-01-01 00:00:00
abstract::A prospective study was performed in 17 patients with achalasia of the esophagus determining the manometric characteristics of the gastroesophageal sphincter, correlating it with histological analysis by biopsies taken during surgery at the distal narrowed segment of the esophagus, at the location of the sphincter. Th...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01308293
更新日期:1985-10-01 00:00:00
abstract::Gastroenterologists are in a unique position to assist women with chronic gastrointestinal disorders in order to optimize their health prior to pregnancy. Women, whether with chronic conditions or not, and their infants are more likely to be healthy when pregnancies are planned. Achieving a planned pregnancy at the id...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章,评审
doi:10.1007/s10620-016-4383-z
更新日期:2017-01-01 00:00:00
abstract::The morphologic characteristics of ductlike tubular complexes were studied in human acute pancreatitis. Pancreatic specimens were obtained from 10 patients who were operated on for acute pancreatitis. Immunocytochemistry for pancreatic enzymes, keratin, actin, and carcinoembryonic antigen were combined with lectin-bin...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01536153
更新日期:1989-01-01 00:00:00
abstract:BACKGROUND:The Child-Turcotte-Pugh (CTP) score is a widely used and validated predictor of long-term survival in cirrhosis. However, the cutpoints for stratifying laboratory variables in CTP have never been validated. OBJECTIVE:The objective of this study was to identify evidence-based cutpoints for the CTP laboratory...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-016-4239-6
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Obesity is associated with a proinflammatory state. AIM:To determine whether obesity at diagnosis is a risk factor for Crohn's disease vs. ulcerative colitis and also vs. community controls and whether there is a U-shaped relationship between body mass index at diagnosis and risk of Crohn's disease versus u...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-010-1541-6
更新日期:2011-03-01 00:00:00
abstract::Modern methods of diagnosing diarrhea-predominant irritable bowel syndrome (D-IBS) require a "diagnosis of exclusion" approach. In this study we aim to test the diagnostic ability of using the fluctuation of frequency and consistency of bowel patterns in IBS to discriminate it from other causes of diarrhea. Eligible s...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-008-0694-z
更新日期:2010-01-01 00:00:00