Dissolution of cholesterol ductal stones in the biliary tree with medium-chain glycerides.

abstract：:Hepatocellular carcinoma (HCC) is a highly morbid and prevalent cancer globally. While high quality evidence for mortality benefit of HCC surveillance is lacking, early detection of HCC is likely beneficial as prognosis is highly correlated with tumor stage. High risk populations, including patients with cirrhosis and...

journal_title：Digestive diseases and sciences

authors： Deng LX,Mehta N

更新日期：2020-12-01 00:00:00

abstract：:To test the role of immune reactivity in the pathogenesis of hepatitis C, serum soluble immune factors were measured in a cohort of 57 patients with chronic hepatitis C, and in 20 healthy subjects. Levels of interleukin-1 beta, granulocyte-macrophage colony-stimulating factor, tumor necrosis factor-alpha, and interleu...

journal_title：Digestive diseases and sciences

authors： Quiroga JA,Martin J,Pardo M,Carreño V

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Fulminant hepatic failure (FHF) is a devastating syndrome, which sometimes results in death or liver transplantation, in which inflammation would aggravate the development of fetuin-A which would act as an anti-inflammatory factor and may be an available approach to attenuate FHF. AIMS:The purpose of this s...

journal_title：Digestive diseases and sciences

authors： Zhang P,Shen H,Huang J,Wang H,Zhang B,Zhou R,Zhong B,Fan X

更新日期：2014-08-01 00:00:00

abstract：:Data about colonic mucosa transport of short-chain fatty acids in cirrhotic patients are still lacking. The aim of the present study was to compare the rectal mucosa transport of n-butyrate and its effect on transport of other electrolytes and endoluminal pH in normal subjects and in cirrhotic patients by using a rect...

journal_title：Digestive diseases and sciences

authors： Onori L,Pimpo MT,Palumbo GC,Gili L,Marchetti G,Saltarelli P,Aggio A,Frieri G

更新日期：2001-10-01 00:00:00

abstract：:The aim of this study was to assess the potential of leflunomide, an immunosuppressant in rheumatoid arthritis, as a second-line immunosuppression treatment of patients with Crohn's disease refractory or intolerant to azathioprine. The study cohort consisted of 24 patients. The primary end point was steroid-free remis...

journal_title：Digestive diseases and sciences

authors： Holtmann MH,Gerts AL,Weinman A,Galle PR,Neurath MF

更新日期：2008-04-01 00:00:00

abstract：:An altered adaptive response of the pancreas and small intestine to nutritional stress has an adverse impact upon nutritional status in elderly humans or senescent rats. We evaluated the effects of a pancreatic extract nutritional supplement on intestinal mucosa adaptation in LPS-treated aged rats. Endotoxemic rats we...

journal_title：Digestive diseases and sciences

authors： Farges MC,Raul F,Cezard JP,Davot P,Meunier MT,Cynober L,Vasson MP

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Mucosal addressin cell adhesion molecule-1 (MAdCAM-1), a member of the immunoglobulin superfamily, is essential for gut-specific homing of leukocytes; however, it has not been well characterized in rhesus macaques. AIMS:To obtain the complete nucleotide sequence of rhesus macaque MAdCAM-1 cDNA and determine...

journal_title：Digestive diseases and sciences

authors： Wang Y,Yao WR,Duan JZ,Xu W,Yang GB

更新日期：2014-10-01 00:00:00

abstract：:There is a high incidence of Campylobacter pylori in the gastric mucosa of patients with duodenal ulcer, gastric ulcer, and nonulcer dyspepsia. Factors that lead to development of this infection are unknown. We hypothesized that delayed solid-phase gastric emptying, a condition characterized by antral stasis, might pr...

journal_title：Digestive diseases and sciences

authors： Barnett JL,Behler EM,Appelman HD,Elta GH

更新日期：1989-11-01 00:00:00

abstract：:Autoregulation of blood flow in the denervated, autoperfused dog stomach was studied before and during local intraarterial infusion of histamine. Histamine caused an increase in gastric blood flow and oxygen uptake. The increased oxygen uptake was due entirely to an increased blood flow, ie, oxygen extraction was not ...

journal_title：Digestive diseases and sciences

authors： Perry MA,Murphree D,Granger DN

更新日期：1982-08-01 00:00:00

abstract：:In previous open studies, misoprostol and metronidazole reduced nonsteroidal anti-inflammatory drug-induced intestinal permeability changes and inflammation respectively. We assessed the effects of indomethacin treatment (50 mg three times a day) for one week with either coadministered metronidazole (400 mg twice a da...

journal_title：Digestive diseases and sciences

authors： Davies GR,Wilkie ME,Rampton DS

更新日期：1993-03-01 00:00:00

abstract：:Heme oxygenase (HO)-1, the rate-limiting enzyme in heme degradation, is induced by oxidative stress and its major end product, bilirubin, is a potent physiological antioxidant. We studied the induction of HO-1 and bilirubin production in intestinal mucosa using a rat model of sepsis. E. coli lipopolysaccharide was adm...

journal_title：Digestive diseases and sciences

authors： Otani K,Shimizu S,Chijiiwa K,Morisaki T,Yamaguchi T,Yamaguchi K,Kuroki S,Tanaka M

更新日期：2000-12-01 00:00:00

abstract：:Intravenous lidocaine was infused at 0.82 ml/min in a concentration of 1.2 mg/ml (2.3 mg/kg) for 120 min in awake chair-restrained baboons (Papio anubis), and measurements of esophageal peristalsis and LES pressure were compared before and after lidocaine or control infusions. Lidocaine produced a progressive and sign...

journal_title：Digestive diseases and sciences

authors： Sinar DR,Carey LC,Cordova C,Fletcher JR,Castell DO

更新日期：1985-11-01 00:00:00

abstract：:Ehlers-Danlos syndrome (EDS) type IV is an autosomal dominant connective tissue disease caused by mutations in the type III collagen gene resulting in extreme tissue fragility. Affected individuals are at risk of dramatic and often fatal complications, mostly spontaneous arterial, uterine, or colonic ruptures. Phenoty...

journal_title：Digestive diseases and sciences

authors： Gelbmann CM,Köllinger M,Gmeinwieser J,Leser HG,Holstege A,Schölmerich J

更新日期：1997-08-01 00:00:00

abstract：:Hepatocellular carcinoma (HCC) as an indication to liver transplant (LT) started as palliative treatment, then moved to potentially curative anti-cancer therapy and more recently entered the era of competition with non-cancer indications, consequent to the need of the society to target equal distribution of the limite...

journal_title：Digestive diseases and sciences

authors： Sposito C,Cucchetti A,Mazzaferro V

更新日期：2019-04-01 00:00:00

abstract：:In recent years, a number of comprehensive reviews have been written on inherited intestinal polyposis syndromes (1-7), but none has dealt specifically with Gardner's syndrome and none has focused on basic research being carried out in an attempt to understand this syndrome and to improve the medical management of aff...

journal_title：Digestive diseases and sciences

authors： Naylor EW,Lebenthal E

更新日期：1980-12-01 00:00:00

abstract：:This study evaluated the gastroprotective activity of DA-6034 against various ulcerogens including ethanol, aspirin, indomethacin, stress, and acetic acid. The basic mechanisms of DA-6034 as a defensive factor such as mucus secretion and endogenous prostaglandin E(2) synthesis were determined. Rats with gastric lesion...

journal_title：Digestive diseases and sciences

authors： Choi SM,Shin JH,Kang KK,Ahn BO,Yoo M

更新日期：2007-11-01 00:00:00

abstract：:Ischemic enterocolitis is a well-recognized entity occurring in cocaine users. Diagnosis is based on the presence of rectal bleeding, abdominal pain, a history of cocaine use, supportive endoscopic and histopathologic findings, and the absence of other etiologic mechanisms of ischemic colitis. In this study, we evalua...

journal_title：Digestive diseases and sciences

authors： Niazi M,Kondru A,Levy J,Bloom AA

更新日期：1997-07-01 00:00:00

abstract：:In this study, we examined the effect of rebamipide, a mucoprotective drug, on gastric ulcer healing in Mongolian gerbils infected with H. pylori. Male Mongolian gerbils were inoculated with H. pylori or vehicle alone 12 hr after the production of an acetic acid-induced gastric ulcer. On day 5, the gerbils inoculated ...

journal_title：Digestive diseases and sciences

authors： Watanabe T,Higuchi K,Hamaguchi M,Tanigawa T,Wada R,Tominaga K,Fujiwara Y,Arakawa T

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND AND AIM:Postoperative infection is not uncommon after hepatectomy. This study assessed the effectiveness of preoperative antibiotic prophylaxis in elective hepatectomy in a randomized clinical trial setting. METHODS:A total of 120 patients who were scheduled to undergo elective hepatectomy were equally rand...

journal_title：Digestive diseases and sciences

authors： Zhou YM,Chen ZY,Li XD,Xu DH,Su X,Li B

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Our previous study has shown that MYO5B is downregulated in gastric cancer. However, the mechanism by which the expression of MYO5B was inhibited remains unknown. METHODS:Inspection of the human MYO5B locus uncovered a large and dense CpG island within the 5' region of this gene. Methylation-specific PCR (M...

journal_title：Digestive diseases and sciences

authors： Dong W,Wang L,Shen R

更新日期：2013-07-01 00:00:00

abstract：:Impaired gallbladder emptying is one of the various factors suggested to be involved in the pathogenesis of gallstones. The present study was undertaken to determine whether gallbladder emptying, endogenous cholecystokinin (CCK) secretion, or their interrelation is altered in patients with gallstones. After intraduode...

journal_title：Digestive diseases and sciences

authors： Masclee AA,Jansen JB,Driessen WM,Geuskens LM,Lamers CB

更新日期：1989-03-01 00:00:00

abstract：:Nos2 knockout mice were compared to wild-type mice for susceptibility to colitis in response to a diet supplemented with deoxycholate, a bile acid increased in the colon of individuals on a high-fat diet. Wild-type mice fed a fat-related diet, supplemented with 0.2% DOC, develop colonic inflammation associated with in...

journal_title：Digestive diseases and sciences

authors： Bernstein H,Holubec H,Bernstein C,Ignatenko NA,Gerner E,Dvorak K,Besselsen D,Blohm-Mangone KA,Padilla-Torres J,Dvorakova B,Garewal H,Payne CM

更新日期：2007-03-01 00:00:00

abstract：:Stevens-Johnson Syndrome (SJS) is a rare but severe dermatological condition that typically occurs after the ingestion of medications such as nonsteroidal drugs, antibiotics, and anticonvulsants. Extracutaneous manifestations of the syndrome can occur and may involve the conjunctiva, trachea, buccal mucosa, gastrointe...

journal_title：Digestive diseases and sciences

authors： Morelli MS,O'Brien FX

更新日期：2001-11-01 00:00:00

abstract：:By using two-color immunofluorescence with fluorescein isothiocyanate (FITC) and phycoerythrin (PE)-labelled monoclonal antibodies and multiparameter flow cytometry, we investigated lamina propria lymphocyte subsets of patients with ulcerative colitis (UC) and Crohn's disease (CD). Leu-3/Leu-2 (CD4/CD8) ratio of lamin...

journal_title：Digestive diseases and sciences

authors： Senju M,Wu KC,Mahida YR,Jewell DP

更新日期：1991-10-01 00:00:00

abstract：:The optimal administration of immunosuppressants such as tacrolimus (Tac) for small-for-size (SFS) grafts, where the functional liver mass is small and must regenerate, has not been reported so far. The aim of this study is to clarify the characteristics of Tac metabolism according to liver volume. Seven-week-old male...

journal_title：Digestive diseases and sciences

authors： Morine Y,Shimada M,Torii M,Imura S,Ikegami T,Kanemura H,Arakawa Y,Hanaoka J,Kanamoto M,Nii A,Yamazaki N

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Liver fibrosis stage determines risk of morbidity and mortality from chronic hepatitis C virus (HCV) infection. Prior data have shown long-term reversal of liver fibrosis, measured by vibration-controlled transient elastography (VCTE), in patients successfully treated with interferon-based therapies. AIM:Ou...

journal_title：Digestive diseases and sciences

authors： Chan J,Gogela N,Zheng H,Lammert S,Ajayi T,Fricker Z,Kim AY,Robbins GK,Chung RT

更新日期：2018-02-01 00:00:00

abstract：:Psychological distress is often observed in patients with gastrointestinal illness. To date, there has been limited research conducted to assess the prevalence and impact of post-traumatic stress disorder (PTSD) in gastrointestinal cohorts. The aim of this systematic review is to review the evidence for the prevalence...

journal_title：Digestive diseases and sciences

authors： Glynn H,Möller SP,Wilding H,Apputhurai P,Moore G,Knowles SR

更新日期：2021-01-12 00:00:00

abstract：:To date, tests of small intestinal passive permeability have involved the ingestion of test molecules whose permeation is assessed indirectly by measuring their urinary recovery. Excretion ratios of marker molecules (eg, lactulose-to-mannitol excretion ratio, LMER) are useful clinically. Measurement of permeability ma...

journal_title：Digestive diseases and sciences

authors： Cox MA,Lewis KO,Cooper BT

更新日期：1999-02-01 00:00:00

abstract：:This study assessed the mucosal antioxidant response during acute (mouse) and chronic (adult human) H. pylori infection and following N-acetylcysteine administration. Antral biopsies were obtained from 44 patients (16 infected, 28 noninfected). Sixty-nine mice were sacrificed after 1 (n = 25), 4 (n = 28), or 6 (n = 16...

journal_title：Digestive diseases and sciences

authors： Matthews GM,Tivey D,Cummins AG,Butler RN

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Hypoxia is an important factor in malignant tumors, and glycolysis is a major metabolic contributor in their development. Glycolytic enzymes have gained increasing attention as potential therapeutic targets because they are associated with cancer-specific metabolism. Fructose-bisphosphate aldolase A (ALDOA),...

journal_title：Digestive diseases and sciences

authors： Li X,Jiang F,Ge Z,Chen B,Yu J,Xin M,Wang J,An L,Wei J,Wu L

更新日期：2019-11-01 00:00:00