Abstract：
:Some patients referred for esophagogastroduodenoscopy (EGD) to evaluate symptoms of dysphagia have normal endoscopies. How best to manage these patients is unclear. We reviewed our experience with empiric esophageal dilation in this setting. Over a five-year period, 40 consecutive patients with esophageal dysphagia and normal EGD underwent empiric esophageal dilation at the time of their endoscopy. Postdilation follow-up was available in 37 of the 40. The patients were divided into two groups depending on whether their dysphagia was to solid food only or to both solids and liquids. The two groups were comparable as regards age, sex, and the frequency of heartburn. Complete resolution of dysphagia was seen in 19 of 20 patients (95%) with solid-food-only dysphagia. In contrast, only two of 17 patients (12%) with solid and liquid dysphagia had complete resolution with empiric dilation, although another six patients (35%) had partial improvement. The difference in response between the two groups was highly significant (P < 0.0001). The response to dilation in patients with dysphagia to solid food only was often long-lasting. Most patients with dysphagia to solid food only and a normal EGD benefit from empiric esophageal dilation performed at the time of their endoscopy. In contrast, few patients with dysphagia to both solids and liquids respond.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Marshall JB,Chowdhury TAdoi
10.1007/BF02088225subject
Has Abstractpub_date
1996-06-01 00:00:00pages
1099-101issue
6eissn
0163-2116issn
1573-2568journal_volume
41pub_type
杂志文章abstract：:MR enteroclysis is becoming a very important imaging modality in the workup and follow-up of small bowel diseases. The technique has many advantages, including the absence of ionizing radiation, ability to control luminal distension, superior tissue characterization, multiplanar capabilities, and mural and extramural ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-005-2700-z
更新日期：2005-06-01 00:00:00
abstract：BACKGROUND:Wnt ligand binding initiates the interaction between Frizzled and Dvl proteins. However, the regulation of Frizzled-Dvl proteins interaction remains largely unknown. AIMS:The present study aims to elucidate the regulation of Frizzled-Dvl interaction by WDR34. METHODS:The protein levels of WDR34 in hepatoce...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-019-05583-w
更新日期：2019-09-01 00:00:00
abstract：:Dientamoeba fragilis is an intestinal protozoan parasite associated with gastrointestinal symptoms. This study was undertaken in a semicommunal group reported to have a high prevalence of this parasite. Stools were collected from 81 adult group members. Intestinal parasites were observed in stool specimens of 45 (56%)...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01324950
更新日期：1983-04-01 00:00:00
abstract：BACKGROUND:Cholangiocarcinoma is a devastating disease with a 2% 5-year survival if the disease has spread outside the liver. The enzyme aspartate beta-hydroxylase (ASPH) has been demonstrated to be highly expressed in cholangiocarcinoma but not in normal bile ducts and found to stimulate tumor cell migration. In addit...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-020-06330-2
更新日期：2020-05-22 00:00:00
abstract：BACKGROUND AND AIMS:Sorafenib is a proven first-line treatment recommended for hepatocellular carcinoma (HCC) patients with portal vein invasion (PVI). However, multiple treatment modalities are used in clinical practice as a first-line option. This study is a prospective, observational, multicenter, cohort study evalu...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-020-06134-4
更新日期：2021-01-01 00:00:00
abstract：:Gastroesophageal reflux disease (GERD) is a common disease in infants and children. Prolonged (24-hr) pH monitoring in the esophagus for determination of increased acid exposure has, together with endoscopy, been the only routinely implemented method for GERD diagnosis. The recently introduced multiple intraluminal im...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-006-9731-y
更新日期：2007-09-01 00:00:00
abstract：:Epidemiological studies have demonstrated a variety of potential environmental factors that may alter susceptibility to chronic pancreatitis (CP) through oxidative/xenobiotic stress; however, a direct causal and mechanistic role has not been established. We aimed (1) to determine the prevalence of functional genetic p...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-005-2790-7
更新日期：2005-07-01 00:00:00
abstract：:Nine patients with concurrent myelodysplastic syndrome (MDS) and inflammatory bowel disease (IBD) were examined. Median age at diagnosis of these patients was similar to the usual age of patients at diagnosis of IBD only. There was a strong predominance of Crohn's disease (seven of nine cases), with an unusually high ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章,评审
doi：10.1007/s10620-007-0090-0
更新日期：2008-07-01 00:00:00
abstract：INTRODUCTION:Voluntary muscle activity, including swallowing, decreases during the night. The association between nocturnal awakenings and swallowing activity is under-researched with limited information on the frequency of swallows during awake and asleep periods. AIM:The aim of this study was to assess nocturnal swa...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章
doi：10.1007/s10620-012-2474-z
更新日期：2013-04-01 00:00:00
abstract：:Acute erosions of the stomach may occur in association with human spinal cord injuries. Erosion of the glandular portion of the stomach also occurs after cervical cord transection in the rat. Reports on the effects of antacids and cimetidine in the prevention of acute "stress" erosions in animals and humans have shown...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01296919
更新日期：1982-03-01 00:00:00
abstract：BACKGROUND:Percutaneous catheter drainage (PCD) performed pro-actively for collections in acute pancreatitis (AP) is associated with better outcomes. However, there are only a few studies describing this protocol. AIM:We aimed to evaluate an aggressive PCD protocol. METHODS:Consecutive patients with AP who underwent ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-020-06116-6
更新日期：2020-12-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF02208653
更新日期：1995-09-01 00:00:00
abstract：:The gold standard for measuring gastric emptying is scintigraphy, either with digestible solids or liquids. Unfortunately, this method is expensive and of limited availability. An alternative could be to use radiopaque markers (ROMs). Our aim was to compare these two tests in healthy volunteers and in patients to see ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1026609808495
更新日期：1999-04-01 00:00:00
abstract：BACKGROUND:Hepatic encephalopathy (HE) is a serious neuropsychiatric complication in both acute and chronic liver disease. AIMS:To establish the utility of a portable noninvasive method to measure ammonia in the breath of healthy subjects and patients with HE. METHODS:The study included 106 subjects: 44 women and 62 ...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-011-1858-9
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:DNA methylation mainly affects tumor suppressor genes in the development of hepatocellular carcinoma (HCC). However, sera methylation of specific genes in hepatitis B virus (HBV)-related HCC remains unknown. AIMS:The purpose of this study was to identify methylation frequencies of sera E-cadherin (CDH1), DN...
journal_title：Digestive diseases and sciences
pub_type： 临床试验,杂志文章
doi：10.1007/s10620-015-3975-3
更新日期：2016-04-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-020-06590-y
更新日期：2020-09-05 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1010653504568
更新日期：2001-08-01 00:00:00
abstract：BACKGROUND/AIM:Transarterial chemoembolization (TACE) is the recommended treatment for patients with Barcelona stage B hepatocellular carcinoma; however, community practice varies from these American Association for the Study of Liver Diseases guidelines. In this study, we sought to assess factors determining outcome a...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-014-3247-7
更新日期：2014-11-01 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章,评审
doi：10.1007/s10620-020-06798-y
更新日期：2021-01-12 00:00:00
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journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01296532
更新日期：1986-11-01 00:00:00
abstract：:The initiating mechanisms involved in colonic injury are currently unknown. The goal of the current study was to examine the role of the inflammatory mediators reactive oxygen metabolites and proteases in an ex vivo model of selective epithelial permeability. Rats were prepared with exteriorized colonic chambers to wh...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF02209017
更新日期：1995-10-01 00:00:00
abstract：BACKGROUND:The early diagnosis of pancreas allograft dysfunction is crucial for the management and long-term survival of transplanted pancreases. We investigated whether intercellular adhesion molecular-1 (ICAM-1), Fas, and Fas ligand (FasL) can be used as novel biomarkers of acute pancreaticoduodenal allograft dysfunc...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-013-2904-6
更新日期：2014-04-01 00:00:00
abstract：:The aim of this study was to investigate the effect of intestinal electrical stimulation on small intestinal dysrhythmia and motion sickness-like symptoms induced by vasopressin. Female dogs chronically implanted with two pairs of electrodes on jejunum serosa were used in a four-session study. Saline and vasopressin w...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/b:ddas.0000030080.60168.01
更新日期：2004-05-01 00:00:00
abstract：BACKGROUND:Helicobacter pylori infection is an established causal factor for non-cardia gastric cancer. H. pylori negative gastric cancer prevalence among US patients is unclear. METHODS:This retrospective cohort study examined H. pylori prevalence among consecutive patients with incident non-cardia gastric adenocarci...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-019-05955-2
更新日期：2020-08-01 00:00:00
abstract：:These studies were done to determine the effects of fluoride (F) on the structure and function of the canine gastric mucosa and the possible protective effects of 16,16-dimethyl-prostaglandin E2 (dmPGE2). A portion of the stomach with its vascular supply intact was mounted in a two-compartment chamber, one side of whi...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1018895207333
更新日期：1997-10-01 00:00:00
abstract：:Prevalence estimates for irritable bowel syndrome from surveys in Western countries are 4.4% to 22%, generally higher in women than men, and only a minority seek health care. There are few studies of bowel patterns in Asian countries. We conducted a survey of a nonpatient population in Ho Chi Minh City, Vietnam, to de...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/s10620-005-9005-0
更新日期：2006-05-01 00:00:00
abstract：:Abnormalities in the gastric pacemaker potentials occur in patients with impaired gastric emptying. It is unclear if treatment effects the underlying rhythm or if normalization of dysrhythmias is important. We examined the effect of cisapride using surface electrogastrograms and radionuclide gastric emptying studies o...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01308614
更新日期：1993-08-01 00:00:00
abstract：:Colonic mucus is decreased in a rat model of spastic constipation, and some types of water-insoluble dietary fiber increase colonic mucus when consumed by rats for several weeks. However, little is known about the effect of water-soluble dietary fiber on the colonic mucus. The aim of the present study was to investiga...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1023/a:1010644021888
更新日期：2001-07-01 00:00:00
abstract：:The association of chronic intestinal pseudoobstruction with ophthalmoplegia has been reported previously in visceral myopathies. We report a case of this association in which muscle mitochondria had a crystalline appearance, a dense core, and decreased cytochrome c oxidase and succinate cytochrome c reductase activit...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF01307743
更新日期：1992-03-01 00:00:00
abstract：:The motor function of the gallbladder after partial distal gastrectomy for gastric carcinoma (Billroth-I reconstruction) and its relationship to the motor function of the stomach was investigated using a double-isotope method. In this method, [99mTc]N-54-pyridoxyl-5-methyltryptophan ([99mTc]PMT) was utilized as a trac...
journal_title：Digestive diseases and sciences
pub_type： 杂志文章
doi：10.1007/BF02064968
更新日期：1995-04-01 00:00:00
