A fulminant hepatic failure model in the rat: involvement of interleukin-1beta and tumor necrosis factor-alpha.

abstract：:Metoclopramide tablets have been approved for use in the acute and chronic management of diabetic gastroparesis. Its efficacy as an antiemetic has been well documented. We measured the acute and chronic effects of oral metoclopramide on gastric liquid emptying in 12 diabetic patients with symptoms of stasis using scin...

journal_title：Digestive diseases and sciences

authors： Schade RR,Dugas MC,Lhotsky DM,Gavaler JS,Van Thiel DH

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVES:Lifestyle and demographic risk factors for the development of oesophageal adenocarcinoma developing from columnar-lined oesophagus are not well defined. METHODS:Demographic and lifestyle factors, endoscopy and histology reports were extracted from 1,761 subjects from seven UK centres. The associations of co...

journal_title：Digestive diseases and sciences

authors： Gatenby PA,Caygill CP,Ramus JR,Charlett A,Watson A

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Procedure-induced bleeding is a major complication after endoscopic intervention. AIMS:The aim of this study was to investigate the risk of endoscopy-related bleeding in patients with chronic hematologic thrombocytopenia. METHODS:We investigated endoscopy-related bleeding in 175 procedures performed on 108...

journal_title：Digestive diseases and sciences

authors： Oh HJ,Park JM,Yoon SB,Lee HH,Lim CH,Kim JS,Cho YK,Lee BI,Cho YS,Choi MG

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Treatment with tumor necrosis factor-α (TNF-α) inhibitors in patients with Crohn's disease (CD) is associated with potentially serious infections, including tuberculosis (TB) and hepatitis B virus (HBV). We assessed the cost-effectiveness of extensive TB screening and HBV screening prior to initiati...

journal_title：Digestive diseases and sciences

authors： van der Have M,Oldenburg B,Fidder HH,Belderbos TD,Siersema PD,van Oijen MG

更新日期：2014-03-01 00:00:00

abstract：:The changes in plasma and duodenal cholecystokinin (CCK) concentrations after pancreatic duct occlusion were examined in rats. The rats were sacrificed 1, 3, 7, 10, 14, and 30 days after occlusion of the duct. Histological examination showed acute inflammation on days 1 and 3 after duct occlusion, interstitial fibrosi...

journal_title：Digestive diseases and sciences

authors： Miyasaka K,Funakoshi A,Jimi A,Nakamura R,Matsumoto M,Kitani K

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:Computed tomography (CT) and magnetic resonance (MR) enterography are now widely used to diagnose and monitor Crohn's disease. AIM:We sought to assess the use of enterography for management of inflammatory bowel disease (IBD) in our medical center. METHODS:We performed a retrospective review of all patient...

journal_title：Digestive diseases and sciences

authors： Patel NS,Pola S,Muralimohan R,Zou GY,Santillan C,Patel D,Levesque BG,Sandborn WJ

更新日期：2014-04-01 00:00:00

abstract：:Leptin is a 16-kDa nonglycosylated protein primarily secreted from the adipocytes of white fat; minor levels of regulated leptin expression also occurs at other sites such as placenta, skeletal muscle, the stomach fundus, and culture-activated hepatic stellate cells (HSCs). Leptin is primarily involved in the regulati...

journal_title：Digestive diseases and sciences

authors： Bethanis SK,Theocharis SE

更新日期：2006-10-01 00:00:00

abstract：:The oral intake of food is important for the observed compensatory hyperplasia in the remnant small intestine after resection but the molecular events governing this response are not known. Peptides, of molecular weight 4500 and 1000 daltons, present in the the proximal intestine for 96 hr after resection and mitogeni...

journal_title：Digestive diseases and sciences

authors： Grey VL,Morin CL

更新日期：1988-01-01 00:00:00

abstract：:Among 56 cases who presented to Kanto-Teishin Hospital complaining of bloody diarrhea or considerable hematochezia of acute onset, 8 cases (14.3%) were considered due to colitis associated with oral ampicillin therapy. The bloody diarrhea, often with abdominal cramps, began 2-7 days after starting the treatment. The d...

journal_title：Digestive diseases and sciences

authors： Sakurai Y,Tsuchiya H,Ikegami F,Funatomi T,Takasu S,Uchikoshi T

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND:Data on ERCP nurses and associate (ERCP-NA) training and comfort are lacking. Healthcare industry representative (HCIR) influence may be greater in low-volume units (LVUs) due to decreased procedure and device familiarity. AIM:The aim of this study was to compare ERCP-NA training, safety, and HCIR relations...

journal_title：Digestive diseases and sciences

authors： Keswani RN,Malpas P,Lynch SE,Coté GA

更新日期：2016-03-01 00:00:00

abstract：:We explored the function of the intestine's mucosal barrier to foreign antigen entry in Crohn's disease. Macroscopically and microscopically uninvolved areas of the small intestines of patients with Crohn's disease were examined. We studied 27 endoscopic biopsy samples from 17 patients with Crohn's disease and 14 samp...

journal_title：Digestive diseases and sciences

authors： Malin M,Isolauri E,Pikkarainen P,Karikoski R,Isolauri J

更新日期：1996-07-01 00:00:00

abstract：:A discrepancy exists on the effects of somatostatin on the absorption of nutrients: in humans, absorption was found to be reduced, whereas in rats no effects were observed. However, intestinal absorption might be influenced by the transit rate of contents. This was not considered in previous studies. Therefore, we inv...

journal_title：Digestive diseases and sciences

authors： Eisenbraun J,Ehrlein HJ

更新日期：1996-05-01 00:00:00

abstract：AIMS:To determine whether temporary fecal diversion for refractory colonic and/or perianal Crohn's disease can lead to clinical remission and restoration of intestinal continuity after optimization of medical therapy. METHODS:We retrospectively reviewed our prospectively maintained database of patients treated at the ...

journal_title：Digestive diseases and sciences

authors： Bafford AC,Latushko A,Hansraj N,Jambaulikar G,Ghazi LJ

更新日期：2017-08-01 00:00:00

abstract：:The effects of intestinal resection on several intestinal parameters have been studied in the large intestine of rats one month after the surgical operation. The results show that both 50% and 80% distal small bowel resection increased net fluid absorption and mucosal permeability and caused expansion of the intercell...

journal_title：Digestive diseases and sciences

authors： Vázquez CM,Molina MT,Ilundaín A

更新日期：1989-11-01 00:00:00

abstract：:A detailed comparison was made of the bile acid composition in gallstones (brown pigment stones) and paired bile and liver from both affected and unaffected lobes by gallstones, which were taken at operation from 16 patients with hepatolithiasis, with the aim of elucidating whether stone formation is derived from poss...

journal_title：Digestive diseases and sciences

authors： Shoda J,Tanaka N,He BF,Matsuzaki Y,Osuga T,Miyazaki H

更新日期：1993-11-01 00:00:00

abstract：:Although various types of artificial liver support systems (ALSSs) including a hybrid type have been made, few are practical ALSSs for treatment of acute and/or chronic hepatic failure. Titanium oxide (TiO(2)), a stable material, dismantles various materials using a photocatalytic action under ultraviolet irradiation....

journal_title：Digestive diseases and sciences

authors： Shinohara H,Shimada M,Ikemoto T,Morine Y,Imura S,Fujii M,Imaizumi T,Murayama M,Aiba Y

更新日期：2007-09-01 00:00:00

abstract：:The purpose of this study was to evaluate the inhibitory activity of selenium-enriched probiotics against pathogenic Escherichia coli (E. coli) in vitro and in vivo. Escherichia coli was co-cultured in vitro with each probiotic strain individually, and a mixture of the four strains and its population was counted at va...

journal_title：Digestive diseases and sciences

authors： Yang J,Huang K,Qin S,Wu X,Zhao Z,Chen F

更新日期：2009-02-01 00:00:00

abstract：:To investigate the possible role of pepsin in ulceration induced by hydrogen ion back-diffusion, the ratio of alkali-labile pepsinogen to total pepsinogen was studied during the course of aspirin- and taurocholate-induced gastric ulceration in comparison with the changes in the ion permeability and histological findin...

journal_title：Digestive diseases and sciences

authors： Ohe K,Yokoya H,Kitaura T,Kunita T,Miyoshi A

更新日期：1980-11-01 00:00:00

abstract：:Basal gastric acid output was analyzed prospectively in 110 patients with endoscopically documented duodenal ulcer disease to determine the frequency of gastric acid hypersecretion in patients with bleeding versus nonbleeding ulcers. Thirty-eight patients with stigmata of an actively or recently bleeding duodenal ulce...

journal_title：Digestive diseases and sciences

authors： Collen MJ,Kalloo AN,Sheridan MJ

更新日期：1993-02-01 00:00:00

abstract：:Methionine (Meth) is an essential amino acid involved in DNA methylation and glutathione biosynthesis. We examined the effect of Meth on the development of steatohepatitis. Rats were fed (five weeks) amino acid-based Meth-choline-sufficient (A-MCS) or total deficient (MCD) diets and gavaged daily (two weeks) with vehi...

journal_title：Digestive diseases and sciences

authors： Oz HS,Chen TS,Neuman M

更新日期：2008-03-01 00:00:00

abstract：:Some benign and malignant diseases develop on the background of chronic gastritis or duodenitis. The present study was performed in order to determine the magnitude of these background changes with relations to symptomatology and life style in the general population. Examinations were performed in 501 volunteers (age ...

journal_title：Digestive diseases and sciences

authors： Borch K,Jönsson KA,Petersson F,Redéen S,Mårdh S,Franzén LE

更新日期：2000-07-01 00:00:00

abstract：:We studied effects of graded concentrations of intragastric calcium on acid secretion, residual gastric volume, and serum gastrin and calcium levels. Intragastric titration was performed with solutions of isotonic mannitol or mannitol plus 2.5, 6, 16, 39, and 97 mM CaCl(2) in 10 normal and eight duodenal ulcer subject...

journal_title：Digestive diseases and sciences

authors： Barclay G,Maxwell V,Grossman MI,Solomon TE

更新日期：1983-05-01 00:00:00

abstract：:Left-sided portal hypertension is a rare clinical syndrome which may lead to bleeding from isolated gastric varices. Pancreatic disease is the most common etiology. Left-sided portal hypertension should be considered in the presence of gastrointestinal bleeding with normal liver function and unexplained splenomegaly. ...

journal_title：Digestive diseases and sciences

authors： Köklü S,Coban S,Yüksel O,Arhan M

更新日期：2007-05-01 00:00:00

abstract：:The effects on the sphincter of Oddi of intravenous administration of dipyrone, 2.5 g; tramadol, 50 mg; indomethacin, 75 mg; N-butylscopolamine, 20 mg; and nitroglycerin, 1 mg, in comparison to physiological saline were assessed in a single-blind study in 36 patients hospitalized with upper abdominal pain. Basal sphin...

journal_title：Digestive diseases and sciences

authors： Brandstätter G,Schinzel S,Wurzer H

更新日期：1996-09-01 00:00:00

abstract：:The release of intestinal gastrin was examined using the isolated vascularly and luminally perfused rat duodenum. Results show that duodenal gastrin was released into both the intestinal lumen and circulation. The basal release of immunoreactive gastrin (IRG) into the lumen was 23.3 +/- 1.8 pg/min and that into the va...

journal_title：Digestive diseases and sciences

authors： Fujimiya M,Kwok YN

更新日期：1997-03-01 00:00:00

abstract：:Not much is known about the relationship between portal hemodynamics and the grades of cirrhosis. Using pulsed Doppler ultrasonography, we studied portal vein diameter, portal flow velocity, and portal blood flow rate in 37 patients with liver cirrhosis (11 Child's A, 13 Child's B, and 13 Child's C) and 10 healthy con...

journal_title：Digestive diseases and sciences

authors： Chawla Y,Santa N,Dhiman RK,Dilawari JB

更新日期：1998-02-01 00:00:00

abstract：:Lactose malabsorption was studied, by hydrogen breath test, in 72 adults suffering from irritable bowel syndrome, in 20 ulcerative colitis patients, and in 69 healthy subjects. The minimum dose of lactose required to cause a positive breath test was determined, and the symptoms caused and the resulting hydrogen elimin...

journal_title：Digestive diseases and sciences

authors： Sciarretta G,Giacobazzi G,Verri A,Zanirato P,Garuti G,Malaguti P

更新日期：1984-12-01 00:00:00

abstract：:Four patients treated with the herbal medicine syo-saiko-to (xiao-chai-hu-tang) exhibited acute drug-induced liver injury. The latent period was one and a half to three months. All of the patients showed a rise in aminotransferases after readministration or challenge test. The liver histology revealed centrilobular co...

journal_title：Digestive diseases and sciences

authors： Itoh S,Marutani K,Nishijima T,Matsuo S,Itabashi M

更新日期：1995-08-01 00:00:00

abstract：:Intestinal bacterial overgrowth (IBO) has been suggested to play a pathogenic role in patients with nonalcoholic fatty liver disease (NAFLD). Delayed intestinal transit may contribute to IBO development. Ten nondiabetic patients with NAFLD and abnormal liver enzymes were recruited. Ten healthy individuals, matched by ...

journal_title：Digestive diseases and sciences

authors： Soza A,Riquelme A,González R,Alvarez M,Pérez-Ayuso RM,Glasinovic JC,Arrese M

更新日期：2005-06-01 00:00:00

abstract：:An intravenous injection of diphenylthiocarbazone (dithizone), a zinc chelator, induces selective killing and rapid regeneration of Paneth cells, which have a large amount of zinc in their cytoplasmic granules. We examined the expression pattern of transforming growth factor (TGF) -alpha and TGF-beta1 in this regenera...

journal_title：Digestive diseases and sciences

authors： Seno H,Sawada M,Fukuzawa H,Morita Y,Takaishi S,Hiai H,Chiba T

更新日期：2001-05-01 00:00:00