HMGA2 elicits EMT by activating the Wnt/β-catenin pathway in gastric cancer.

abstract：:The effect of luminal 150 mmol saline, 0.05-0.2% (w/v) lysolecithin, and 5-20% (v/v) ethanol was studied on the mucosal morphology of the proximal small intestine in conscious guinea pigs as well as on the mucosal penetration and transfer to portal venous blood of luminal horseradish peroxidase (HRP). No ultrastructur...

journal_title：Digestive diseases and sciences

authors： Talbot RW,Foster JR,Hermon-Taylor J,Grant DA

更新日期：1984-11-01 00:00:00

abstract：:Detecting plasma protein loss from the stomach is quite difficult by measuring fecal alpha1-AT clearance because alpha1-AT is rapidly destroyed in the gastric juice at values below pH 3. We examined protein loss from the stomach using fecal alpha1-AT clearance with lansoprazole, a proton pump inhibitor. A 38-year-old ...

journal_title：Digestive diseases and sciences

authors： Takeda H,Nishise S,Furukawa M,Nagashima R,Shinzawa H,Takahashi T

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND AND AIM:Second harmonic generation (SHG) is a novel imaging technology that could provide optical biopsy during endoscopy with advantages over current technology. SHG has the unique ability to evaluate the amount of extracellular matrix collagen protein and its alignment. METHODS:Hematoxylin- and eosin-stai...

journal_title：Digestive diseases and sciences

authors： Birk JW,Tadros M,Moezardalan K,Nadyarnykh O,Forouhar F,Anderson J,Campagnola P

更新日期：2014-07-01 00:00:00

abstract：:The gut microbiota is a vast ensemble of microorganisms inhabiting the mammalian gastrointestinal tract that can impact physiologic and pathologic processes. However, our understanding of the underlying mechanism for the dynamic interaction between host and gut microbiota is still in its infancy. The highly evolved ep...

journal_title：Digestive diseases and sciences

authors： Ye J,Wu W,Li Y,Li L

更新日期：2017-05-01 00:00:00

abstract：:Resistant starch is by definition that part of starch that escapes digestion in the small bowel. Cecal fermentation of resistant starch into short-chain fatty acids will result subsequently in a decrease in pH. Thus, resistant starch may have the same effect on colonic luminal contents and mucosa as some fiber compone...

journal_title：Digestive diseases and sciences

authors： van Munster IP,Tangerman A,Nagengast FM

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:The receptor for formylated peptides, formyl peptide receptor 1 (FPR1), potently activates and serves as a chemoattractant receptor for neutrophils. AIM:Given the abundance of neutrophils in the inflamed colon, our aim was to determine if the FPR1 mediates colonic neutrophil migration, using the dextran sod...

journal_title：Digestive diseases and sciences

authors： Farooq SM,Stadnyk AW

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND AND AIMS:The detailed risk factors such as bleeding pattern, comorbidities, and medication usage of patients with obscure gastrointestinal bleeding (OGIB) are largely unknown. We evaluated the risk factors related to ulcerative and vascular lesions of the small intestine diagnosed by capsule endoscopy or bal...

journal_title：Digestive diseases and sciences

authors： Okamoto J,Tominaga K,Sugimori S,Kato K,Minamino H,Ominami M,Fukunaga S,Nagami Y,Kamata N,Yamagami H,Tanigawa T,Shiba M,Watanabe T,Fujiwara Y,Arakawa T

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Cognitive deficiency noted post-liver transplantation might be a result of consequential metabolic derangement before liver transplantation. Long-chain polyunsaturated fatty acids, especially arachidonic acid (AA) and docosahexaenoic acid (DHA), affect the development of the central nervous system and its ab...

journal_title：Digestive diseases and sciences

authors： Chen CC,Huang LT,Tain YL,Chaung HC,Hsieh CS,Eng HL,Wei YC,Yang CY

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Studies examining the mortality risk of inflammatory bowel disease (IBD) have yielded conflicting results, and most do not account for recent advancements made in the treatment of Crohn's disease (CD) and ulcerative colitis (UC). We aim to assess the overall, premature, and cause-specific mortality in IBD pa...

journal_title：Digestive diseases and sciences

authors： Nocerino A,Feathers A,Ivanina E,Durbin L,Swaminath A

更新日期：2019-06-01 00:00:00

abstract：:Cholecystectomy is one of the commonest surgical procedures in the Western world, with more than half a million procedures performed annually in the United States alone. In recent years, studies of gallstone pathogenesis and gallbladder disease have increasingly focused on abnormal gallbladder motility in the pathogen...

journal_title：Digestive diseases and sciences

authors： Patankar R,Ozmen MM,Bailey IS,Johnson CD

更新日期：1995-11-01 00:00:00

abstract：:Using northern blot analysis and immunohistochemistry, we assessed the expression and distribution of human epidermal growth factor receptor-1 (HER-1), HER-2, and HER-3 in pancreatic tissues obtained from patients with acute pancreatitis (AP). Overall, HER-1, HER-2, and HER-3 mRNA levels were similar in the normal pan...

journal_title：Digestive diseases and sciences

authors： Ebert M,Friess H,Büchler MW,Korc M

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Chronic megacolon is a rare disease of the colonic motor function characterized by a permanent increase in colonic diameter. METHODS:We reviewed electronic medical records of all patients diagnosed with chronic megacolon from 1999 to 2014 at Mayo Clinic. Our aim was to summarize clinical and motility featur...

journal_title：Digestive diseases and sciences

authors： O'Dwyer RH,Acosta A,Camilleri M,Burton D,Busciglio I,Bharucha AE

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Mucosal addressin cell adhesion molecule-1 (MAdCAM-1), a member of the immunoglobulin superfamily, is essential for gut-specific homing of leukocytes; however, it has not been well characterized in rhesus macaques. AIMS:To obtain the complete nucleotide sequence of rhesus macaque MAdCAM-1 cDNA and determine...

journal_title：Digestive diseases and sciences

authors： Wang Y,Yao WR,Duan JZ,Xu W,Yang GB

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Although the use of cold snare polypectomy (CSP) has spread rapidly, its safety for pedunculated (Ip) polyps remains controversial. In particular, the outcomes of hot snare polypectomy (HSP) and CSP for Ip polyps have not been previously compared. AIMS:This study evaluated whether the rate of delayed postpo...

journal_title：Digestive diseases and sciences

authors： Arimoto J,Chiba H,Ashikari K,Fukui R,Tachikawa J,Okada N,Suto T,Kawano N,Niikura T,Kuwabara H,Nakaoka M,Ida T,Goto T,Nakajima A

更新日期：2020-07-04 00:00:00

abstract：BACKGROUND AND AIMS:Treatment with tumor necrosis factor-α (TNF-α) inhibitors in patients with Crohn's disease (CD) is associated with potentially serious infections, including tuberculosis (TB) and hepatitis B virus (HBV). We assessed the cost-effectiveness of extensive TB screening and HBV screening prior to initiati...

journal_title：Digestive diseases and sciences

authors： van der Have M,Oldenburg B,Fidder HH,Belderbos TD,Siersema PD,van Oijen MG

更新日期：2014-03-01 00:00:00

abstract：:Papillary stenosis is an imprecisely defined clinical syndrome which eludes definitive diagnosis. In this study we evaluated 26 patients with suspected papillary stenosis by manometric examination of the sphincter of Oddi done during ERCP examination. Basal pressure in the sphincter of Oddi was elevated in 14 of the p...

journal_title：Digestive diseases and sciences

authors： Bar-Meir S,Geenen JE,Hogan WJ,Dodds WJ,Stewart ET,Arndorfer RC

更新日期：1979-03-01 00:00:00

abstract：UNLABELLED:There is a wide choice of fecal occult blood tests (FOBTs) for colorectal cancer screening. GOAL:To highlight the issues applicable when choosing a FOBT, in particular which FOBT is best suited to the range of screening scenarios. Four scenarios characterize the constraints and expectations of screening pro...

journal_title：Digestive diseases and sciences

authors： Young GP,Symonds EL,Allison JE,Cole SR,Fraser CG,Halloran SP,Kuipers EJ,Seaman HE

更新日期：2015-03-01 00:00:00

abstract：:We describe the first reported case of generalized tonic-clonic seizures induced by meperidine premedication for a colonoscopy procedure in a 63-year-old woman with Alzheimer's disease. The active metabolite of meperidine, normeperidine, is postulated to be the precipitating cause of the seizures, although a cholinest...

journal_title：Digestive diseases and sciences

authors： Nagler J,Hammarth PM,Poppers DM

更新日期：2008-01-01 00:00:00

abstract：:The effect of chronic ethanol ingestion on the ability of the small intestine to absorb zinc was examined in male Sprague-Dawley rats. Six rats were fed the Lieber-Decarli liquid rat diet for 1 month during which 36% of their total calories were provided as ethanol, while their pair fed controls received these calorie...

journal_title：Digestive diseases and sciences

authors： Antonson DL,Vanderhoof JA

更新日期：1983-07-01 00:00:00

abstract：:The indications for surgery on cavernous hemangiomas, the most common benign tumors of the liver, remain unclear. This study reviewed 43 patients with cavernous hemangioma of the liver who underwent hepatic resection from 1984 to 2000. Patients were divided into three groups based on the reasons for surgery. Group I c...

journal_title：Digestive diseases and sciences

authors： Tsai HP,Jeng LB,Lee WC,Chen MF

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Diagnosis of eosinophilic esophagitis (EoE) requires manual quantification of tissue eosinophils. Eosinophil peroxidase (EPX) is an eosinophil-specific, cytoplasmic granule protein released during degranulation. AIMS:The objective of this study was to evaluate image analysis of EPX immunohistochemistry as a...

journal_title：Digestive diseases and sciences

authors： Wright BL,Doyle AD,Shim KP,Pai RK,Barshow SM,Horsley-Silva JL,Luo H,Rank MA,Jacobsen EA,Katzka DA,Kita H,Dellon ES

更新日期：2020-04-04 00:00:00

abstract：:A variety of human disease conditions are associated with chronic intestinal disorders or enteropathies that are characterized by intestinal inflammation, increased gut permeability, and reduced capacity to absorb nutrients. Such disruptions in the homeostasis of the gastrointestinal (GI) tract can lead to symptoms of...

journal_title：Digestive diseases and sciences

authors： Petschow BW,Burnett BP,Shaw AL,Weaver EM,Klein GL

更新日期：2015-01-01 00:00:00

abstract：:Gastrin-secreting tumors have been identified in ectopic locations including the ovary; the mechanisms regulating gastrin gene expression, its distribution, and signaling pathways in these ectopic tissues are not known. The purpose of our present study was to determine: (1) whether the gastrin gene and peptide could b...

journal_title：Digestive diseases and sciences

authors： Kim HJ,Evers BM,Banker NA,Greeley GH Jr,Hellmich MR,Thompson JC,Townsend CM Jr

更新日期：1998-07-01 00:00:00

abstract：:We compared the growth rate of locally recurrent hepatocellular carcinoma (HCC) with that of primary HCC. After the first treatment by transcatheter arterial chemoembolization (TACE), 60 locally recurrent HCC nodules were reviewed. The tumor volume doubling time (DT) of locally recurrent HCC was significantly shorter ...

journal_title：Digestive diseases and sciences

authors： Tezuka M,Hayashi K,Kubota K,Sekine S,Okada Y,Ina H,Irie T

更新日期：2007-03-01 00:00:00

abstract：:We postulated that coadministration of cholylsarcosine with ursodeoxycholic acid might provide additional benefit to primary biliary cirrhosis patients with an incomplete response to ursodeoxycholic acid. Our aim was to test the tolerability and the effect of adjuvant cholylsarcosine on liver tests and plasma choleste...

journal_title：Digestive diseases and sciences

authors： Ricci P,Hofmann AF,Hagey LR,Jorgensen RA,Rolland Dickson E,Lindor KD

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:Helminth infection has been proven to reduce the severity of experimental inflammatory bowel disease (IBD). The excretory-secretory proteins of helminths play an important role in the process of immunomodulation. AIMS:In the present study, we aimed to investigate the protective potential of recombinant Tric...

journal_title：Digestive diseases and sciences

authors： Du L,Tang H,Ma Z,Xu J,Gao W,Chen J,Gan W,Zhang Z,Yu X,Zhou X,Hu X

更新日期：2011-10-01 00:00:00

abstract：:When radiolabeled 1,25-dihydroxyvitamin D3 is added to the perfusion medium of a rat liver perfusion system, a polar metabolite of 1,25-dihydroxyvitamin D3 is formed in the liver and excreted in the bile. Addition of radiolabeled 1,25-dihydroxyvitamin D3 to the perfusion medium without a liver in the circuit results i...

journal_title：Digestive diseases and sciences

authors： Kumar R,Nagubandi S,Londowski JM

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:Birth characteristics, including weight and gestational age, may be associated with risk of Barrett's esophagus (BE), the only known precursor for esophageal adenocarcinoma; however, data are limited. AIMS:To examine associations between various birth characteristics and BE, and whether these associations a...

journal_title：Digestive diseases and sciences

authors： Shiota S,El-Serag HB,Thrift AP

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:The use of volatile organic compounds (VOCs) in bile was recently studied and appeared promising for diagnosis of malignancy. Noninvasive diagnosis of malignant biliary strictures by using VOCs in urine has not been studied. AIM:To identify potential VOCs in urine to diagnose malignant biliary strictures. ...

journal_title：Digestive diseases and sciences

authors： Navaneethan U,Parsi MA,Lourdusamy D,Grove D,Sanaka MR,Hammel JP,Vargo JJ,Dweik RA

更新日期：2015-07-01 00:00:00

abstract：:Phosphorylation/dephosphorylation of intracellular proteins are important steps in the regulation of cell growth. Okadaic acid, an inhibitor of the serine/threonine protein phosphatases 1 and 2A, is a potent tumor promoter. This effect may be through the inhibition of dephosphorylation (termed "hyperphosphorylation") ...

journal_title：Digestive diseases and sciences

authors： Hirai A,Bold RJ,Ishizuka J,Hirai M,Townsend CM Jr,Thompson JC

更新日期：1996-10-01 00:00:00