Effect of resistant starch on colonic fermentation, bile acid metabolism, and mucosal proliferation.

abstract：BACKGROUND AND AIMS:Biosimilar approval, such as Inflectra™ (CT-P13) for treating ulcerative colitis (UC) and Crohn's disease (CD), has reduced direct drug costs. Though clinicians are comfortable with biosimilar use in treatment-naïve patients, there are concerns in some jurisdictions that there are insufficient data ...

journal_title：Digestive diseases and sciences

authors： Bernard EJ,Fedorak RN,Jairath V

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Heartburn is frequently reported by patients with achalasia before treatment. However, the esophageal sensitivity to acid as a possible mediator of this symptom has not been previously evaluated. AIM:To evaluate the prevalence of gastroesophageal reflux symptoms and the esophageal sensitivity to acid perfus...

journal_title：Digestive diseases and sciences

authors： Ponce J,Ortiz V,Maroto N,Ponce M,Bustamante M,Garrigues V

更新日期：2011-03-01 00:00:00

abstract：:Alterations of small intestinal sensory thresholds and small intestinal dysmotility are associated with functional dyspepsia. Because gastric and duodenal afferents partly project to the same areas, we postulated that patients with functional dyspepsia and H. pylori infection would be characterized by lower duodenal s...

journal_title：Digestive diseases and sciences

authors： Holtmann G,Talley NJ,Goebell H

更新日期：1996-07-01 00:00:00

abstract：:Intravenous administration of platelet-activating factor (PAF) induces extensive damage in rat gastric mucosa. The aim of the present study was to examine whether the presence or absence of acid in the gastric lumen could modify the PAF-induced gastric damage. The effects of inhibition of basal and pentagastrin-stimul...

journal_title：Digestive diseases and sciences

authors： Piqué JM,Pérez Ayuso RM,Bilbao J,Terés J

更新日期：1991-12-01 00:00:00

abstract：BACKGROUND:Systemic sclerosis (SS) patients with severe esophageal affection have impaired peristalsis. However, motor function evaluated in vivo by manometry and fluoroscopy does not provide detailed information about the individual contraction cycles. AIMS:To apply, for the first time in gastrointestinal (GI) patien...

journal_title：Digestive diseases and sciences

authors： Gregersen H,Villadsen GE,Liao D

更新日期：2011-12-01 00:00:00

abstract：:Turmeric is widely used in Indian cuisine. The main constituents of turmeric are curcumin and its analogues, which are well-known antioxidant compounds. In the present study, we hypothesized that turmeric in curry might increase bowel motility and activate hydrogen-producing bacterial flora in the colon, thereby incre...

journal_title：Digestive diseases and sciences

authors： Shimouchi A,Nose K,Takaoka M,Hayashi H,Kondo T

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Exercise-triggered asthma (ETA) develops when physical activity triggers asthma symptoms during or directly after exercise. In patients prone to symptoms of supra-esophageal reflux, exercise may trigger gastroesophageal reflux (GER), resulting in such symptoms. AIMS:To determine the prevalence of abnormal p...

journal_title：Digestive diseases and sciences

authors： Peterson KA,Samuelson WM,Ryujin DT,Young DC,Thomas KL,Hilden K,Fang JC

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Percutaneous catheter drainage (PCD) performed pro-actively for collections in acute pancreatitis (AP) is associated with better outcomes. However, there are only a few studies describing this protocol. AIM:We aimed to evaluate an aggressive PCD protocol. METHODS:Consecutive patients with AP who underwent ...

journal_title：Digestive diseases and sciences

authors： Gupta P,Gupta J,Kumar C,Samanta J,Mandavdhare H,Sharma V,Sinha SK,Gupta V,Yadav TD,Dutta U,Kochhar R

更新日期：2020-12-01 00:00:00

abstract：:The specificity of polymerase chain reaction monoclonality in the diagnosis of gastric lymphoma was prospectively evaluated. Gastric mucosal tissue from normal gastric mucosa (N = 13), benign gastric ulcers (N = 3), chronic Helicobacter pylori gastritis (N = 3), gastric mucosa-associated lymphoid tissue (N = 16), and ...

journal_title：Digestive diseases and sciences

authors： Weston AP,Banerjee SK,Horvat RT,Cherian R,Campbell DR,Zoubine MN

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Trinitrobenzenesulfonic acid (TNBS)-induced colitis is one of the most widely used experimental colitis models. However, there is no standard procedure for inducing colitis by TNBS because it is difficult to achieve a uniform distribution of colitis. We have developed a modified method of murine TNBS-induced...

journal_title：Digestive diseases and sciences

authors： Terai T,Osawa S,Tani S,Oishi S,Arai Y,Yamada T,Sugimoto M,Furuta T,Kanaoka S,Miyajima H,Sugimoto K

更新日期：2014-07-01 00:00:00

abstract：:To evaluate the effect of halofuginone on trinitrobenzene sulfonic acid (TNBS)-induced colonic injury, rats were given halofuginone (40 microg/kg, intraperitoneally) or saline 1 h before the induction of colitis, and the injections were continued twice daily for 3 days until they were decapitated. High macroscopic and...

journal_title：Digestive diseases and sciences

authors： Karakoyun B,Yüksel M,Ercan F,Salva E,Işik I,Yeğen BC

更新日期：2010-03-01 00:00:00

abstract：:Data on performance characteristics of flexible sigmoidoscopy (FS) between age groups are limited. This study evaluates screening FS in subjects > or = 75 years of age (elderly) compared with ages 50-74 years (general screening population). Data were collected on patient characteristics, insertion depth, procedural di...

journal_title：Digestive diseases and sciences

authors： Pabby A,Suneja A,Heeren T,Farraye FA

更新日期：2005-11-01 00:00:00

abstract：:In previous studies, the majority of patients with the cholestatic liver diseases, primary biliary cirrhosis (PBC) and primary sclerosing cholangitis (PSC), had increased hepatic copper (Cu) levels even in early stages of disease. We prospectively measured hepatic copper content by atomic absorption spectrophotometry ...

journal_title：Digestive diseases and sciences

authors： Kowdley KV,Knox TA,Kaplan MM

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Autofluorescence imaging (AFI), which is a "red flag" technique during Barrett's surveillance, is associated with significant false positive results. The aim of this study was to assess the inter-observer agreement (IOA) in identifying AFI-positive lesions and to assess the overall accuracy of AFI. METHODS:...

journal_title：Digestive diseases and sciences

authors： Mannath J,Subramanian V,Telakis E,Lau K,Ramappa V,Wireko M,Kaye PV,Ragunath K

更新日期：2013-02-01 00:00:00

abstract：:Dysmotility and delayed emptying of the stomach have been reported in patients with chronic renal failure (CRF). The aim of this study was to investigate whether gastric myoelectrical activity was impaired in patients with CRF using electrogastrography. The electrogastrogram (EGG) was recorded in 24 symptomatic patien...

journal_title：Digestive diseases and sciences

authors： Lin X,Mellow MH,Southmayd L 3rd,Pan J,Chen JD

更新日期：1997-05-01 00:00:00

abstract：:The role of HBV precore mutations in the spontaneous reactivation of chronic hepatitis B (CHB) is currently unknown. We studied 10 patients with CHB; five were HBeAg+ (group I) and five were anti-HBe+ (group II). All 10 had spontaneous reactivation of CHB as defined by the appearance of clinical symptoms along with an...

journal_title：Digestive diseases and sciences

authors： Laskus T,Rakela J,Tong MJ,Persing DH

更新日期：1994-09-01 00:00:00

abstract：:Suspected risk factors for adenocarcinoma of the small bowel in Crohn's disease include surgically excluded small bowel loops, chronic fistulous disease, and male sex. Review of all seven University of Chicago cases failed to confirm any suspected risk factor. A case-control study was performed to identify possible al...

journal_title：Digestive diseases and sciences

authors： Lashner BA

更新日期：1992-08-01 00:00:00

abstract：:Although systemic steroids remain as the gold standard for the treatment of acute moderate to severe active ulcerative colitis (UC), 15-57% of patients do not achieve clinical remission. We sought to identify clinical, biological, or radiologic predictive factors of response to steroid treatment in acute UC attacks. T...

journal_title：Digestive diseases and sciences

authors： Bernal I,Mañosa M,Domènech E,Garcia-Planella E,Navarro M,Lorenzo-Zúñiga V,Cabré E,Gassull MA

更新日期：2006-08-01 00:00:00

abstract：:Polycystic liver disease (PCLD) without polycystic kidney is infrequent in clinical setting. Family clustering is found in patients with PCLD, and it is inherited in an autosomal dominant fashion. Through positional cloning in North America and Europe (mostly in Dutch and Finnish descents), mutations in PRKCSH gene on...

journal_title：Digestive diseases and sciences

authors： Yang AM,Shih SC,Chu CH,Wang TE,Yang WS

更新日期：2010-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Matrix metalloproteinase-2 (MMP-2), a type IV collagenase secreted by activated hepatic stellate cells (HSCs), is upregulated in chronic liver disease and is considered a profibrotic mediator due to its proliferative effect on cultured HSCs and ability to degrade normal liver matrix. Although associ...

journal_title：Digestive diseases and sciences

authors： Radbill BD,Gupta R,Ramirez MC,DiFeo A,Martignetti JA,Alvarez CE,Friedman SL,Narla G,Vrabie R,Bowles R,Saiman Y,Bansal MB

更新日期：2011-02-01 00:00:00

abstract：:A patient with several episodes of jaundice associated with sulfamethoxazole therapy is described. In contrast to the histologic picture of hepatocellular necrosis with or without cholestasis that is generally associated with sulfonamide hepatotoxicity, in the present case a relatively pure cholestatic pattern was fou...

journal_title：Digestive diseases and sciences

authors： Steinbrecher UP,Mishkin S

更新日期：1981-08-01 00:00:00

abstract：:This study was done to examine the role of cyclooxygenase (COX) in lipopolysaccharide (LPS)-induced gastroprotection and gastric stasis. In conscious rats, LPS dose and time dependently increased gastric luminal fluid accumulation. LPS decreased blood flow (laser Doppler) and prevented gastric injury from acidified et...

journal_title：Digestive diseases and sciences

authors： West SD,Suliburk JW,Smith GS,Mercer DW

更新日期：2006-04-01 00:00:00

abstract：:The original version of this article unfortunately contained an error in a couple of reference citation in Discussion Section, paragraph 6. The reference citation number should be changed from [6] to [9] in the below sentences so that it reads. ...

journal_title：Digestive diseases and sciences

authors： Hammer V,Hammer K,Memaran N,Huber WD,Hammer K,Hammer J

更新日期：2018-06-01 00:00:00

abstract：:Duodenogastric reflux (DGR) was assessed with 24-hour gastric bilirubin monitoring in 345 patients (219 men; 49 +/- 13 years) with foregut symptoms and 41 healthy subjects (24 men, 28 +/- 5 years). Bilirubin exposure was measured as percent time above absorbance level 0.25 and excessive DGR was defined above the 95th ...

journal_title：Digestive diseases and sciences

authors： Fein M,Freys SM,Sailer M,Maroske J,Tigges H,Fuchs KH

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Previous studies have shown that healing in intestinal wounds is proportionally faster than skin. Cytokines and growth factors play a major role in these coordinated wound-healing events. We hypothesized that this more rapid intestinal healing is due to an early upregulation of proinflammatory cytokines (IL-...

journal_title：Digestive diseases and sciences

authors： Zubaidi A,Buie WD,Hart DA,Sigalet D

更新日期：2010-06-01 00:00:00

abstract：:The effects of Sulglycotide were evaluated in a pilot study of active H. pylori+ atrophic gastritis. Ten informed patients (mean age 51 +/- 13 years) entered a double-blind study. Five received Sulglycotide 400 mg three times a day for one year, the other 5, placebo. At 0, 30, 90, 270, and 360 days of treatment, patie...

journal_title：Digestive diseases and sciences

authors： Bazuro GE,Dezi A,Pallotta L,Masci P,Teodori L,Trinca ML,Koch M,Capurso L

更新日期：1996-01-01 00:00:00

abstract：:Several plant-derived polysaccharides have been shown to have anti-inflammatory activity in animal models. Ambrotose complex and Advanced Ambrotose are dietary supplements that include aloe vera gel, arabinogalactan, fucoidan, and rice starch, all of which have shown such activity. This study was designed to evaluate ...

journal_title：Digestive diseases and sciences

authors： Koetzner L,Grover G,Boulet J,Jacoby HI

更新日期：2010-05-01 00:00:00

abstract：:Obesity and diet affect the incidence and severity of various types of cancer, including colon cancer. It is not known whether obesity, independent of diet, is a risk factor for colon adenocarcinoma. We used azoxymethane (AOM) to induce colon cancer in mature genetically obese male Zucker rats (fa/fa) on low-fat crude...

journal_title：Digestive diseases and sciences

authors： Weber RV,Stein DE,Scholes J,Kral JG

更新日期：2000-05-01 00:00:00

abstract：:Mutations in the gene encoding the CYP2C-19 enzyme for PPI metabolism have been shown to enhance the chance for a cure in a H. pylori-positive patients using a two-week dual-therapy regimen involving omeprazole and amoxicillin. However, the impact of CYP2C-19 genetic polymorphism on eradication rates of a one-week tri...

journal_title：Digestive diseases and sciences

authors： Miwa H,Misawa H,Yamada T,Nagahara A,Ohtaka K,Sato N

更新日期：2001-11-01 00:00:00

abstract：BACKGROUND:Diarrhea, a major pathological hallmark of inflammatory bowel disease, is characterized by a significant reduction in the expression and function of key intestinal ion transporters. The adoptive naïve CD4+ T cell transfer colitis is an immune-based, chronic colitis mouse model which resembles human Crohn's d...

journal_title：Digestive diseases and sciences

authors： Jayawardena D,Tyagi S,Nazmi A,Olivares-Villagómez D,Dudeja PK

更新日期：2020-06-01 00:00:00