Predictors of clinical response to systemic steroids in active ulcerative colitis.

abstract：:Fasting antroduodenal motor activity was studied in 15 dyspeptic patients with chronic superficial antral gastritis and Helicobacter pylori infection (group A), 10 dyspeptic patients with chronic superficial antral gastritis without Helicobacter pylori infection (group B), and eight healthy control subjects (group C) ...

journal_title：Digestive diseases and sciences

authors： Testoni PA,Bagnolo F,Masci E,Colombo E,Tittobello A

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Helminth infection has been proven to reduce the severity of experimental inflammatory bowel disease (IBD). The excretory-secretory proteins of helminths play an important role in the process of immunomodulation. AIMS:In the present study, we aimed to investigate the protective potential of recombinant Tric...

journal_title：Digestive diseases and sciences

authors： Du L,Tang H,Ma Z,Xu J,Gao W,Chen J,Gan W,Zhang Z,Yu X,Zhou X,Hu X

更新日期：2011-10-01 00:00:00

abstract：:Plasma pancreatic polypeptide (PP) responses to food, secretin (1 CU/kg, intravenous) and bombesin (60 pmol/kg/20 min intravenous) were compared in 14 normal subjects and in 17 patients with chronic pancreatitis and pancreatic insufficiency. Basal plasma PP concentrations were significantly higher in normal subjects t...

journal_title：Digestive diseases and sciences

authors： Lamers CB,Diemel CM,Jansen JB

更新日期：1984-02-01 00:00:00

abstract：:The aim of this study was to assess the efficacy of the combination of endoscopic variceal ligation (EVL) and partial splenic embolization (PSE) compared with EVL alone in cirrhosis patients with thrombocytopenia. In a prospective study, 84 cirrhosis patients with esophageal varices and thrombocytopenia (platelet coun...

journal_title：Digestive diseases and sciences

authors： Ohmoto K,Yoshioka N,Tomiyama Y,Shibata N,Takesue M,Yoshida K,Kuboki M,Yamamoto S

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Systemic sclerosis (SS) patients with severe esophageal affection have impaired peristalsis. However, motor function evaluated in vivo by manometry and fluoroscopy does not provide detailed information about the individual contraction cycles. AIMS:To apply, for the first time in gastrointestinal (GI) patien...

journal_title：Digestive diseases and sciences

authors： Gregersen H,Villadsen GE,Liao D

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND AND AIM:Aberrant methylation of specific genes is frequent event in hepatocellular carcinoma (HCC). Our present study aims to explore the methylation levels of acid phosphatase locus 1 (ACP1), bone morphogenetic protein 4 (BMP4), and testis-specific protein, Y-encoded-like 5 (TSPYL5) and their potential clin...

journal_title：Digestive diseases and sciences

authors： Qiu X,Hu B,Huang Y,Deng Y,Wang X,Zheng F

更新日期：2016-01-01 00:00:00

abstract：:Several epidemiological studies have demonstrated a close association between Helicobacter pylori infection and carcinoma of the mid- or distal stomach. If this can be shown to be a causal association, eradication of the organism may prevent later development of cancer. Several mechanisms have been proposed by which H...

journal_title：Digestive diseases and sciences

authors： Hahm KB,Lee KJ,Kim JH,Cho SW,Chung MH

更新日期：1998-09-01 00:00:00

abstract：:The release of intestinal gastrin was examined using the isolated vascularly and luminally perfused rat duodenum. Results show that duodenal gastrin was released into both the intestinal lumen and circulation. The basal release of immunoreactive gastrin (IRG) into the lumen was 23.3 +/- 1.8 pg/min and that into the va...

journal_title：Digestive diseases and sciences

authors： Fujimiya M,Kwok YN

更新日期：1997-03-01 00:00:00

abstract：:Although various types of artificial liver support systems (ALSSs) including a hybrid type have been made, few are practical ALSSs for treatment of acute and/or chronic hepatic failure. Titanium oxide (TiO(2)), a stable material, dismantles various materials using a photocatalytic action under ultraviolet irradiation....

journal_title：Digestive diseases and sciences

authors： Shinohara H,Shimada M,Ikemoto T,Morine Y,Imura S,Fujii M,Imaizumi T,Murayama M,Aiba Y

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:We hypothesized that the severity of dextran sodium sulfate (DSS)-induced colitis could differ between DSS preparations of the same molecular weight, and that this difference may be affected by the sulfur content. To test this, we used three DSS preparations of similar molecular weights but with different su...

journal_title：Digestive diseases and sciences

authors： Bamba S,Andoh A,Ban H,Imaeda H,Aomatsu T,Kobori A,Mochizuki Y,Shioya M,Nishimura T,Inatomi O,Sasaki M,Saitoh Y,Tsujikawa T,Araki Y,Fujiyama Y

更新日期：2012-02-01 00:00:00

abstract：:Small bowel tumors are rare, accounting for 1-2% of all gastrointestinal neoplasms. We sought to determine the diagnostic and therapeutic impact of double-balloon enteroscopy (DBE) in patients with small bowel tumors. Between January 2005 and March 2008, 78 patients underwent 96 DBE. All nine patients (seven males; me...

journal_title：Digestive diseases and sciences

authors： Almeida N,Figueiredo P,Lopes S,Gouveia H,Leitão MC

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND AND AIM:The association between nonalcoholic fatty liver disease (NAFLD) and apolipoprotein C3 gene (APOC3) promoter region single-nucleotide polymorphisms (SNPs) rs2854117 and rs2854116 is controversial. The aim of this study was to investigate the relationship between other polymorphisms of APOC3 and NAFLD...

journal_title：Digestive diseases and sciences

authors： Zhang RN,Zheng RD,Mi YQ,Zhou D,Shen F,Chen GY,Zhu CY,Pan Q,Fan JG

更新日期：2016-08-01 00:00:00

abstract：:Lansoprazole, a proton pump inhibitor, exerts prominent antiulcer activity via both antisecretory and mucosal protective actions. Although the antisecretory action has been explained by inactivation of (H+, K+)-ATPase in parietal cells, the mode of mucosal protective action remains to be elucidated. In the present stu...

journal_title：Digestive diseases and sciences

authors： Inada I,Satoh H

更新日期：1996-04-01 00:00:00

abstract：:The results of 88 consecutive small-bowel enemas were compared retrospectively with the results of 52 routine small-bowel series and 50 barium enemas done in the same patients. Ninety-six percent of the diagnoses made by small-bowel enema were correct, as compared to only 65% made by routine small-bowel series. The in...

journal_title：Digestive diseases and sciences

authors： Gurian L,Jendrzejewski J,Katon R,Bilbao M,Cope R,Melnyk C

更新日期：1982-12-01 00:00:00

abstract：:Isolated case reports in which symptomatic hearing loss develops suddenly during the course of inflammatory bowel disease (IBD) have been reported, but the presence of subclinical sensorineural hearing loss (SNHL) associated with IBD has been investigated in only two preliminary studies. In order to research this furt...

journal_title：Digestive diseases and sciences

authors： Akbayir N,Caliş AB,Alkim C,Sökmen HM,Erdem L,Ozbal A,Bölükbaş F,Akbayir N

更新日期：2005-10-01 00:00:00

abstract：:In a Caucasian woman with a history of ocular and pulmonary sarcoidosis, the occurrence of sclerosing peritonitis with exudative ascites but without any of the well-known causes of this syndrome prompts us to consider that sclerosing peritonitis is a manifestation of sarcoidosis. The dramatic improvement that occurred...

journal_title：Digestive diseases and sciences

authors： Ngô Y,Messing B,Marteau P,Nouël O,Pasquiou A,Lavergne A,Rambaud JC

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Approximately 233,898 individuals in the Veterans Affairs healthcare network are hepatitis C virus (HCV)-infected, making the Veterans Affairs the single largest provider of HCV care in the USA. Direct-acting antiviral treatment regimens for HCV offer high cure rates. However, these medications pose an enorm...

journal_title：Digestive diseases and sciences

authors： Maier MM,Zhou XH,Chapko M,Leipertz SL,Wang X,Beste LA

更新日期：2018-06-01 00:00:00

abstract：:The evaluation of a group of polyamine analogs as agents to ameliorate diarrhea-predominant irritable bowel syndrome is described. Each compound was assessed when administered subcutaneously in a psychological stress-induced model of irritable bowel syndrome in rodents for its ability to reduce stool output in a dose-...

journal_title：Digestive diseases and sciences

authors： Bergeron RJ,Wiegand J,Fannin TL

更新日期：2001-12-01 00:00:00

abstract：:Endoscopic papillary balloon dilatation (EPBD) has been recently used in conjunction with endoscopic sphincterotomy (EST) for the removal of common bile duct (CBD) stones. The present study was aimed at assessing the safety and outcome of sequential EPBD following EST for CBD stones. A total of 74 patients (43 females...

journal_title：Digestive diseases and sciences

authors： Kochhar R,Dutta U,Shukla R,Nagi B,Singh K,Wig JD

更新日期：2009-07-01 00:00:00

abstract：:Small intestinal bacterial overgrowth (SIBO) has a high incidence in dogs and, as in humans, is difficult to diagnose. The aim of this study was to determine the diagnostic significance of serum unconjugated bile acid concentrations in dogs with bacterial overgrowth. Fasting sera were obtained from 23 dogs: 10 with cu...

journal_title：Digestive diseases and sciences

authors： Melgarejo T,Williams DA,O'Connell NC,Setchell KD

更新日期：2000-02-01 00:00:00

abstract：:Methionine (Meth) is an essential amino acid involved in DNA methylation and glutathione biosynthesis. We examined the effect of Meth on the development of steatohepatitis. Rats were fed (five weeks) amino acid-based Meth-choline-sufficient (A-MCS) or total deficient (MCD) diets and gavaged daily (two weeks) with vehi...

journal_title：Digestive diseases and sciences

authors： Oz HS,Chen TS,Neuman M

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Forkhead box P3 (FOXP3)+ regulatory T cells (Tregs) are critical for controlling inflammation in the gastrointestinal tract. There is a paradoxical increase of mucosal FOXP3+ T cells in patients with inflammatory bowel disease (IBD). These FOXP3+ cells were recently shown to include interleukin (IL)-17A-prod...

journal_title：Digestive diseases and sciences

authors： Lord JD,Valliant-Saunders K,Hahn H,Thirlby RC,Ziegler SF

更新日期：2012-11-01 00:00:00

abstract：:Crohn's disease (CD) is a heterogeneous disorder. A genetic linkage to chromosome 16 (IBD1) has been previously observed and replicated in unrelated populations. Recently, in this region, NOD2/CARD15 has been identified as a susceptibility gene. The aim of this report is to determine whether this gene is implicated in...

journal_title：Digestive diseases and sciences

authors： Zouiten-Mekki L,Zaouali H,Boubaker J,Karoui S,Fekih M,Matri S,Hamzaoui S,Filali A,Chaabouni H,Hugot JP

更新日期：2005-01-01 00:00:00

abstract：:Acid inhibition increases gastric mucosal susceptibility to damage by luminal acid. This might be due to reduced metabolic CO2 and bicarbonate whereas, during normal acid, secretion cytoprotective CO2/HCO3- production parallels acid production. Metabolic activity and mucosal damage caused by luminal acid perfusion was...

journal_title：Digestive diseases and sciences

authors： Glauser M,Bauerfeind P,Feil W,Riegler M,Fraser R,Blum AL

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Endoscopic submucosal dissection (ESD) criteria are histologically categorized by early gastric cancer (EGC) with differentiated- and undifferentiated-type histology. However, EGC is histologically heterogenous and there have been no separate criteria for EGC with mixed-type histology [EGC-MH; differentiated...

journal_title：Digestive diseases and sciences

authors： Bang CS,Yang YJ,Lee JJ,Baik GH

更新日期：2020-01-01 00:00:00

abstract：:This study was designed to determine the effect of a newly synthesized benzimidazole derivative NC-1300-B on H+, K+-ATPase (proton pump) in the hog gastric mucosa and on the basal gastric acid secretion and necrotizing agent-induced gastric lesions in rats. NC-1300-B inhibited the proton pump in a concentration-depend...

journal_title：Digestive diseases and sciences

authors： Okabe S,Akimoto Y,Yamasaki S,Nagai H

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Numerous experiments have shown that alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) are present in cells of various cancer and can play role in carcinogenesis. In previous investigations we have found elevated levels of alcohol dehydrogenase class III activity in pancreatic cancer cells. It ca...

journal_title：Digestive diseases and sciences

authors： Jelski W,Zalewski B,Szmitkowski M

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Probucol, a lipid-lowering agent with antioxidant effects, is effective in normalizing liver enzymes in patients with nonalcoholic steatohepatitis (NASH). We studied changes in the liver histology of patients with NASH after use of probucol for one year. METHODS:Ten patients with biopsy-proven NASH were inc...

journal_title：Digestive diseases and sciences

authors： Merat S,Aduli M,Kazemi R,Sotoudeh M,Sedighi N,Sohrabi M,Malekzadeh R

更新日期：2008-08-01 00:00:00

abstract：:We examined the effect of sildenafil, an inhibitor of phosphodiesterase subtype 5, that catalyzes hydrolysis of 3',5'-cyclic guanosine monophosphate (cGMP), on indomethacin-induced small-intestinal ulceration in rats and investigated the mechanism of this action, especially in relation to endogenous nitric oxide (NO)....

journal_title：Digestive diseases and sciences

authors： Kato N,Mashita Y,Kato S,Mitsufuji S,Yoshikawa T,Takeuchi K

更新日期：2009-11-01 00:00:00

abstract：BACKGROUND:Hepatitis C virus (HCV) recurrence after liver transplantation (LT) is universal and tends to be more aggressive. Data on post-transplant HCV genotype 4 treatment is scarce. The aim of this study is to assess the safety and efficacy of pegylated interferon alpha-2a (PEG-IFN) in combination with ribavirin in ...

journal_title：Digestive diseases and sciences

authors： Al-Hamoudi W,Mohamed H,Abaalkhail F,Kamel Y,Al-Masri N,Allam N,Alqahtani S,Al-Sofayan M,Khalaf H,Al-Sebayel M,Al-Jedai A,Abdo A

更新日期：2011-06-01 00:00:00