Abstract:
:Plasma pancreatic polypeptide (PP) responses to food, secretin (1 CU/kg, intravenous) and bombesin (60 pmol/kg/20 min intravenous) were compared in 14 normal subjects and in 17 patients with chronic pancreatitis and pancreatic insufficiency. Basal plasma PP concentrations were significantly higher in normal subjects than in patients with chronic pancreatitis, but there was considerable overlap between the groups. Ingestion of food induced significant increases in plasma PP both in normal subjects and in patients with chronic pancreatitis, whereas secretin and bombesin significantly increased plasma PP levels in normal subjects only. The PP responses to the three stimuli were significantly larger in normal subjects than in patients with chronic pancreatitis, but there was marked overlap. Calculation of the peak to basal plasma PP ratio did not result in better discrimination between the two groups. In normal subjects there were no significant correlations between the PP responses to the three stimuli, whereas in patients with chronic pancreatitis these responses were significantly correlated. Furthermore, in patients with chronic pancreatitis the PP responses to the various stimuli were significantly correlated with the basal plasma PP level.
journal_name
Dig Dis Scijournal_title
Digestive diseases and sciencesauthors
Lamers CB,Diemel CM,Jansen JBdoi
10.1007/BF01317049subject
Has Abstractpub_date
1984-02-01 00:00:00pages
102-8issue
2eissn
0163-2116issn
1573-2568journal_volume
29pub_type
杂志文章abstract::In conscious dogs with gastric and duodenal Thomas fistulas, we studied the effect of ethanol on plasma concentrations of gastrin. Ethanol was given either as an infusion into a peripheral vein (1.95 M, 200 ml/hr) or into the duodenum (0.95 M, 400 ml/hr) or as an intragastric bolus injection. The effect of the intraga...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01296856
更新日期:1984-01-01 00:00:00
abstract::The aim of the study was to assess the value of quantitative attenuation values (Hounsfield units) and of gallstone pattern by computerized tomography in predicting response to bile acid therapy. We carried out a prospective study in a multicenter setting on 90 consecutive outpatients with radiolucent gallstones. All ...
journal_title:Digestive diseases and sciences
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1007/BF02208664
更新日期:1995-09-01 00:00:00
abstract:BACKGROUND AND AIMS:Avoidance of gluten is critical for individuals with celiac disease (CD), but there is also concern that "extreme vigilance" to a strict gluten-free diet may increase symptoms such as anxiety and fatigue, and therefore, lower quality of life (QOL). We examined the associations of QOL with energy lev...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-018-4936-4
更新日期:2018-06-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01347884
更新日期:1985-03-01 00:00:00
abstract::Longitudinal shortening of the esophagus during peristaltic contraction has been previously analyzed globally using spaced mucosal clips. This method gives a relatively crude measurement. In this study, local longitudinal shortening (LLS) was evaluated using simultaneous high-resolution endoluminal ultrasound (HREUS) ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-006-3092-4
更新日期:2006-01-01 00:00:00
abstract:BACKGROUND AND AIM:There is no consensus regarding the benefit of eradicating Helicobacter pylori (H. pylori) infection in patients with functional dyspepsia (FD). We intended to compare the symptom response to H. pylori eradication in FD patients in presence or absence of microscopic duodenitis (MD). METHODS:Patients...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-014-3285-1
更新日期:2015-01-01 00:00:00
abstract::We evaluated the sequence diversity of the hypervariable region 1 (HVR1) of hepatitis C virus (HCV) in HCV-infected patients in whom the mode of transmission is unknown. The sequence diversity of HVR1 in 26 Japanese patients with chronic HCV infection of unknown mode of transmission (UT) was compared with 17 patients ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1026693512265
更新日期:1999-10-01 00:00:00
abstract::Current research in gene delivery to the liver is focused on the intravenous, intraarterial, intraportal, or intratumoral route. Another possible route for gene delivery is via the common bile duct through endoscopic retrograde cholangiopancreatography (ERCP). Whether bile and pancreatic juice have any effect on gene ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1005431703317
更新日期:2000-02-01 00:00:00
abstract::Stevens-Johnson Syndrome (SJS) is a rare but severe dermatological condition that typically occurs after the ingestion of medications such as nonsteroidal drugs, antibiotics, and anticonvulsants. Extracutaneous manifestations of the syndrome can occur and may involve the conjunctiva, trachea, buccal mucosa, gastrointe...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章,评审
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更新日期:2001-11-01 00:00:00
abstract::In situ steady-state, single-pass small intestine perfusions in rats were carried out to compare the effect of the bicarbonate and citrate World Health Organization oral rehydration solutions and a base precursor-free solution on intestinal water and electrolyte transport after inducing intestinal secretion with purif...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01308341
更新日期:1992-01-01 00:00:00
abstract::Intestinal injury 4-48 hr after cytotoxic therapy (etoposide phosphate, 100 mg/kg body weight [bw], intravenously [i.v.]) was studied in rats using ligated intestinal loops. Chromium-51 ethylenediaminetetraacetic acid ((51)Cr-EDTA) and rubidium-86 chloride ((86)RbCl) were deposited intraluminally to determine the exte...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-005-2926-9
更新日期:2005-09-01 00:00:00
abstract::Effects of selective beta-adrenoceptor agonists on rectosigmoid motility during prolonged rectal distension were studied in 12 healthy volunteers in a double-blind, randomized fashion. Continuous distension was performed with a balloon in the proximal part of the rectum. Pressure was recorded by this balloon and by a ...
journal_title:Digestive diseases and sciences
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF01320259
更新日期:1985-06-01 00:00:00
abstract:BACKGROUND:Enhanced cell expression of MAdCAM-1 is critical in tissue recruitment of lymphocytes in response to stimuli expressing the α4β7 integrin. MAdCAM-1 is well characterized in gut mucosa with emerging evidence of hepatic expression. AIMS:(i) Compare quantitative/semi-quantitatively MAdCAM-1 expression in relat...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-013-2755-1
更新日期:2013-09-01 00:00:00
abstract::Our aims were to measure antral axial forces in patients with suspected upper gut dysmotilities and to compare the number of antral contractions detected by an axial force catheter and by manometric sensors in the distal antrum and pylorus. Fifteen patients (2 men, 13 women; mean age 42 years) underwent studies for 3 ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF02213125
更新日期:1996-04-01 00:00:00
abstract::Five healthy young adults developed an acute self-limiting ulcerative esophagitis. Two had definite evidence of herpes virus being present and a third one had appropriate changes in herpes simplex viral titer. All cases followed a characteristic and similar course consisting of sudden onset of odynophagia, multiple di...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01489322
更新日期:1979-07-01 00:00:00
abstract::To determine if organic anions contribute to the diarrhea of inflammatory bowel disease, we measured osmolality, electrolytes, short-chain fatty acids, lactic acid, and some Krebs cycle anions in 24-hr fecal collections from 18 patients with chronic ulcerative colitis, 20 with Crohn's disease of the colon, and 16 norm...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01536987
更新日期:1988-11-01 00:00:00
abstract::This paper reports the results of a multicenter prospective study of 188 consecutive patients affected by gastric ulcer, verified by endoscopy, in whom the frequency of a mycotic infection of the lesion was evaluated as well as the eventual influence of such pathology on the efficiency of medical treatment, the healin...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01308206
更新日期:1985-02-01 00:00:00
abstract:BACKGROUND/AIM:We have previously reported that bee venom (BV) has a protective role against acute pancreatitis (AP). However, the effects of apamin, the major compound of BV, on AP have not been determined. The aim of this study was to evaluate the effects of apamin on cerulein-induced AP. METHODS:AP was induced via ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-013-2800-0
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:Diabetic gastroparesis is a common complication of diabetes mellitus, which mainly affects women. Previous studies have demonstrated that oxidative stress is involved in its onset and development. AIMS:This study evaluated the role of vitamin C on diabetes-associated gastric dysmotility. METHODS:Female rat...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-017-4632-9
更新日期:2017-09-01 00:00:00
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journal_title:Digestive diseases and sciences
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doi:10.1007/s10620-019-06002-w
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF02087766
更新日期:1994-08-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章,评审
doi:10.1007/s10620-005-2805-4
更新日期:2005-10-01 00:00:00
abstract::We compared changes in gastric mucosal blood flow (GMBF) and left gastric artery blood flow (LGABF) in response to pharmacological, physiological, and pathological stimuli. GMBF and LGABF were measured by the hydrogen gas clearance and perivascular ultrasonic transit time techniques, respectively, under baseline condi...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1018807009266
更新日期:1997-09-01 00:00:00
abstract:AIMS:To determine whether temporary fecal diversion for refractory colonic and/or perianal Crohn's disease can lead to clinical remission and restoration of intestinal continuity after optimization of medical therapy. METHODS:We retrospectively reviewed our prospectively maintained database of patients treated at the ...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-017-4618-7
更新日期:2017-08-01 00:00:00
abstract::Clinical features and liver biopsy findings were studied in six patients with nonalcoholic steatohepatitis associated with hyalin. A comparative study was made on the ultrastructure of the hyalin in one patient with nonalcoholic steatohepatitis and in one patient with alcoholic hepatitis. The patients, all over 50 yea...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/BF01296754
更新日期:1982-04-01 00:00:00
abstract::The 1993 Milwaukee Cryptosporidium outbreak posed several questions regarding appropriate management and prognosis of inflammatory bowel disease patients acutely infected with this organism. We prospectively identified and monitored 12 patients with stable ulcerative colitis or Crohn's disease who suffered abrupt clin...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1023/a:1018828507990
更新日期:1997-08-01 00:00:00
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journal_title:Digestive diseases and sciences
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doi:10.1007/s10620-009-1120-x
更新日期:2010-10-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-007-0144-3
更新日期:2008-08-01 00:00:00
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journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-011-1640-z
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND AND AIMS:Percutaneous gastrostomy (PEG) is a common inpatient procedure. Prior data from National Inpatient Sample (NIS) in 2006 reported a mortality rate of 10.8% and recommended more careful selection of PEG candidates. This study assessed for improvement in the last 10 years in mortality rate and complica...
journal_title:Digestive diseases and sciences
pub_type: 杂志文章
doi:10.1007/s10620-020-06396-y
更新日期:2020-06-19 00:00:00