Temporal expression of cytokines in rat cutaneous, fascial, and intestinal wounds: a comparative study.

abstract：:Low or minimal doses of aspirin are widely used for prevention of cardiovascular diseases. Aspirin is known to produce severe adverse gastrointestinal effects, such as bleeding and perforation. Less is known about the risk associated with minidose aspirin. Our aim was to assess the possible association of upper gastro...

journal_title：Digestive diseases and sciences

authors： Sapoznikov B,Vilkin A,Hershkovici M,Fishman M,Eliakim R,Niv Y

更新日期：2005-09-01 00:00:00

abstract：:Inhibitors of gastric acid secretion are efficient drugs in the treatment of acid-related diseases. However, by reducing gastric acidity, hypergastrinemia develops. Gastrin regulates its target cell, the enterochromaffin (ECL) cell, both functionally and tropicaly. Long-term hypergastrinemia in whatever species studie...

journal_title：Digestive diseases and sciences

authors： Waldum HL,Gustafsson B,Fossmark R,Qvigstad G

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Subjects with fatty liver disease (FLD) can show increased hepatic 2-deoxy-2-((18)F)fluoro-D-glucose (FDG) uptake, but the role of hepatic inflammation has not been explored. AIMS:We investigated whether hepatic inflammatory response, as implicated by elevated serum markers, is associated with increased liv...

journal_title：Digestive diseases and sciences

authors： Hong SP,Noh TS,Moon SH,Cho YS,Lee EJ,Choi JY,Kim BT,Lee KH

更新日期：2014-03-01 00:00:00

abstract：:Octreotide is an effective therapeutic option in controlling secretory diarrhea of varied etiology. However, marked patient-to-patient differences in the antidiarrheal effects necessitate titration of octreotide dose in individual patients to achieve optimal symptom control. A consensus development panel established g...

journal_title：Digestive diseases and sciences

authors： Harris AG,O'Dorisio TM,Woltering EA,Anthony LB,Burton FR,Geller RB,Grendell JH,Levin B,Redfern JS

更新日期：1995-07-01 00:00:00

abstract：:In the United States, more women than men seek health-care services for symptoms of irritable bowel syndrome (IBS). A number of explanations are given for this gender difference including the higher rates of somatic non-gastrointestinal symptoms and increased psychological distress reported by women with IBS. However,...

journal_title：Digestive diseases and sciences

authors： Cain KC,Jarrett ME,Burr RL,Rosen S,Hertig VL,Heitkemper MM

更新日期：2009-07-01 00:00:00

abstract：:We conducted a randomized prospective study with extended intraesophageal pH monitoring on two consecutive nights to test the hypothesis that a waterbed (WB) might increase recumbent acid exposure compared to a regular bed (RB). We studied 10 controls (mean age 29 years; five males, five females) with no history of re...

journal_title：Digestive diseases and sciences

authors： Wang JC,Castell DO,Sinclair JW,Wu WC

更新日期：1989-10-01 00:00:00

abstract：:The presence in the esophagus of three distinct entities--Barrett's mucosa, Crohn's disease, and adenocarcinoma--is a very rare finding. In a 60-year-old man with a long history of heartburn and recently developed dysphagia, narrowing of the distal esophagus was found to be related to the presence of Barrett's mucosa....

journal_title：Digestive diseases and sciences

authors： Delpre G,Mor C,Avidor I,Gutman H,Leisser A,Kott I,Kadish U

更新日期：1989-02-01 00:00:00

abstract：:This study aimed at establishment of adequate evaluation of intestinal viability before release of the strangulated intestine by measuring electrical properties. In rats a 20-cm segment of the distal ileum and mesentery was strangulated. The intestine was strangulated for 0, 2, 15, 45, 90, and 120 min. The conductance...

journal_title：Digestive diseases and sciences

authors： Matsuo H,Hirose H,Mori Y,Takagi H,Iwata H,Yamada T,Sakamoto K,Yasumura M

更新日期：2004-04-01 00:00:00

abstract：:The indications for surgery on cavernous hemangiomas, the most common benign tumors of the liver, remain unclear. This study reviewed 43 patients with cavernous hemangioma of the liver who underwent hepatic resection from 1984 to 2000. Patients were divided into three groups based on the reasons for surgery. Group I c...

journal_title：Digestive diseases and sciences

authors： Tsai HP,Jeng LB,Lee WC,Chen MF

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Gastroparesis is a heterogeneous disorder. Patient characteristics and treatment responsiveness may differ based on the extent of delay in gastric emptying. AIMS:Characterize gastroparesis patients based on the degree of delay in gastric emptying, and assess the relationship of patient demographics, symptom...

journal_title：Digestive diseases and sciences

authors： Navas CM,Wadas ED,Zbib NH,Crowell MD,Lacy BE

更新日期：2020-04-18 00:00:00

abstract：BACKGROUND AND AIMS:Fatigue significantly impacts the quality of life of patients with inflammatory bowel disease (IBD). This study aimed to assess the effect of a personalized, intensive exercise program on fatigue, health-related quality of life (HRQoL), and cardiorespiratory fitness in patients with quiescent IBD an...

journal_title：Digestive diseases and sciences

authors： van Erp LW,Roosenboom B,Komdeur P,Dijkstra-Heida W,Wisse J,Horjus Talabur Horje CS,Liem CS,van Cingel REH,Wahab PJ,Groenen MJM

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Progressive hepatic fibrosis with development of cirrhosis is a feature of almost all chronic liver diseases. AIMS:We assessed the performance of Fibroscan in patients with chronic viral hepatitis, and in comparison with and combined with several surrogate serum markers for predicting cirrhosis. METHODS:In...

journal_title：Digestive diseases and sciences

authors： Lee MH,Cheong JY,Um SH,Seo YS,Kim DJ,Hwang SG,Yang JM,Han KH,Cho SW

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND:Metabolic syndrome contributing to nonalcoholic fatty liver disease (NAFLD) can lead to hepatic dysfunction, steatohepatitis, cirrhosis, and hepatocellular carcinoma. AIMS:In this study, we tested whether diet-induced fatty liver in a mouse model physiologically mimicked human NAFLD, and whether transcripti...

journal_title：Digestive diseases and sciences

authors： Almanza D,Gharaee-Kermani M,Zhilin-Roth A,Rodriguez-Nieves JA,Colaneri C,Riley T,Macoska JA

更新日期：2019-05-01 00:00:00

abstract：:In toxic liver injury, proliferation of preexisting hepatocytes helps restore liver mass and function. While loss of liver mass per se stimulates hepatocyte proliferation, exogenous mitogens have a potential role in enhancing liver regeneration. The aim of this study was to characterize the effects of the mitogen, tri...

journal_title：Digestive diseases and sciences

authors： Malik R,Saich R,Rahman T,Hodgson H

更新日期：2006-12-01 00:00:00

abstract：:Consumption of high-fiber diets has been recommended prior to fecal blood testing to increase bleeding from polyps, cancer, and other lesions associated with mucosal erosion in the gastrointestinal tract. The effect of a high-fiber diet on fecal hemoglobin loss was examined in 17 healthy subjects during two dietary pe...

journal_title：Digestive diseases and sciences

authors： Slavin JL,Melcher EA,Sundeen M,Schwartz S

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:The heterogeneous patterns and trends in tobacco consumption contribute to regional and gender differences in the burden of gastric cancer attributable to smoking. AIMS:To estimate the proportion and absolute number of gastric cancer cases that can be attributed to smoking in different countries, in 2012 an...

journal_title：Digestive diseases and sciences

authors： Peleteiro B,Castro C,Morais S,Ferro A,Lunet N

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Diagnosis of pediatric inflammatory bowel diseases (IBD) remains challenging. We aimed at the value of immunohistochemical assessment of CD30+ lymphocytes in the intestinal mucosa in differential diagnosis between pediatric Crohn's disease (CD) and ulcerative colitis (UC) and its utility as a predictor of fu...

journal_title：Digestive diseases and sciences

authors： Fabian O,Hradsky O,Drskova T,Mikus F,Zamecnik J,Bronsky J

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND:The early diagnosis of pancreas allograft dysfunction is crucial for the management and long-term survival of transplanted pancreases. We investigated whether intercellular adhesion molecular-1 (ICAM-1), Fas, and Fas ligand (FasL) can be used as novel biomarkers of acute pancreaticoduodenal allograft dysfunc...

journal_title：Digestive diseases and sciences

authors： Dong GH,Li XF,Li JZ,Zhang ZD,Hu WM,Luo YH,Li ZD,Tian BL,He MX,Zhu XW

更新日期：2014-04-01 00:00:00

abstract：:To date few therapies have been shown to reliably prevent the evolution of Crohn's disease (CD). The traditional Chinese medicine, Tripterygium wilfordii Hook F (TWHF), has both immunomodulatory and anti-inflammatory activities. Our aim was to investigate the potential efficacy of T2, the major constituent of extracts...

journal_title：Digestive diseases and sciences

authors： Ren J,Tao Q,Wang X,Wang Z,Li J

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Activation of the transcription factor NF-κB and expression of pro-inflammatory mediators have been considered as major events of acute pancreatitis (AP). Karyopherin alpha 2 (KPNA2), a member of the importin α family, reportedly modulates p65 subcellular localization. AIM:This study aimed to investigate th...

journal_title：Digestive diseases and sciences

authors： Cai Y,Shen Y,Gao L,Chen M,Xiao M,Huang Z,Zhang D

更新日期：2016-03-01 00:00:00

abstract：:Solitary rectal ulcer syndrome (SRUS) is sufficiently uncommon that the clinician or general pathologist may lack familiarity with the disorder and may confuse it with other inflammatory bowel diseases. To evaluate the role of collagen staining in facilitating the differential diagnosis of SRUS, an initial open review...

journal_title：Digestive diseases and sciences

authors： Levine DS,Surawicz CM,Ajer TN,Dean PJ,Rubin CE

更新日期：1988-11-01 00:00:00

abstract：:Food allergy, a commonly increasing problem worldwide, defined as an adverse immune response to food. A variety of immune-related effector cells such as mast cells, eosinophils, neutrophils, and T cells are involved in food-related allergic responses categorized as IgE mediated, non-IgE mediated, and mixed (IgE and no...

journal_title：Digestive diseases and sciences

authors： Manohar M,Verma AK,Upparahalli Venkateshaiah S,Goyal H,Mishra A

更新日期：2017-12-01 00:00:00

abstract：:Five cases of granular cell tumor of the esophagus are reported. In four cases, the tumor was an asymptomatic, incidental finding. In one case, a larger granular cell tumor presented with dysphagia and required local surgical excision. Long-term follow-up in three cases revealed no evidence of tumor progression. Esoph...

journal_title：Digestive diseases and sciences

authors： Brady PG,Nord HJ,Connar RG

更新日期：1988-10-01 00:00:00

abstract：:Na/H exchanger-1 (NHE-1) isoform regulates intracellular pH and protects the esophageal mucosa. These functions are compromised in gastroesophageal reflux disease (GERD); however, the role and the underlying mechanism of NHE-1 regulation are obscure. To address this issue, NHE-1 protein and mRNA levels were measured b...

journal_title：Digestive diseases and sciences

authors： Siddique I,Khan I

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND AND AIMS:Minimal hepatic encephalopathy is the mildest form of the spectrum of hepatic encephalopathy (HE) that impairs health-related quality of life. We assessed (1) the usefulness of psychometric hepatic encephalopathy score and critical flicker frequency for the diagnosis of minimal hepatic encephalopath...

journal_title：Digestive diseases and sciences

authors： Dhiman RK,Kurmi R,Thumburu KK,Venkataramarao SH,Agarwal R,Duseja A,Chawla Y

更新日期：2010-08-01 00:00:00

abstract：:To define the clinical significance of delayed postsphincterotomy hemorrhage, we reviewed 476 consecutive ERCP procedures performed over a three-year period. Of 250 patients who underwent endoscopic sphincterotomy (ES), five (2%) developed postprocedure hemorrhage, two of whom had immediate, self-limited bleeding that...

journal_title：Digestive diseases and sciences

authors： Gholson CF,Favrot D,Vickers B,Dies D,Wilder W

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Probucol, a lipid-lowering agent with antioxidant effects, is effective in normalizing liver enzymes in patients with nonalcoholic steatohepatitis (NASH). We studied changes in the liver histology of patients with NASH after use of probucol for one year. METHODS:Ten patients with biopsy-proven NASH were inc...

journal_title：Digestive diseases and sciences

authors： Merat S,Aduli M,Kazemi R,Sotoudeh M,Sedighi N,Sohrabi M,Malekzadeh R

更新日期：2008-08-01 00:00:00

abstract：:The effect of dopamine on human gastric and small intestinal interdigestive motility was investigated in 12 subjects. Intestinal motility was recorded by means of a four-lumen polyvinyl probe with four open tips located 15 cm apart, continuously perfused with distilled water. In each subject during the same study, aft...

journal_title：Digestive diseases and sciences

authors： Marzio L,Neri M,Di Giammarco AM,Cuccurullo F,Lanfranchi GA

更新日期：1986-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder with increasing prevalence. However, epidemiologic data have mostly been acquired from small studies. We sought to describe the epidemiology of EoE in the USA, utilizing a large database. METHODS:We queried a commercial database (Exp...

journal_title：Digestive diseases and sciences

authors： Mansoor E,Cooper GS

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Inflammatory bowel disease (IBD) may be initiated following disruption of the intestinal epithelial barrier. This disruption, in turn, permits luminal antigens unfettered access to the mucosal immune system and leads to an uncontrolled inflammatory response. Glycoalkaloids, which are found in potatoes, disru...

journal_title：Digestive diseases and sciences

authors： Iablokov V,Sydora BC,Foshaug R,Meddings J,Driedger D,Churchill T,Fedorak RN

更新日期：2010-11-01 00:00:00