Effects of lipopolysaccharide on gastric stasis: role of cyclooxygenase.

abstract：:This study evaluated the gastroprotective activity of DA-6034 against various ulcerogens including ethanol, aspirin, indomethacin, stress, and acetic acid. The basic mechanisms of DA-6034 as a defensive factor such as mucus secretion and endogenous prostaglandin E(2) synthesis were determined. Rats with gastric lesion...

journal_title：Digestive diseases and sciences

authors： Choi SM,Shin JH,Kang KK,Ahn BO,Yoo M

更新日期：2007-11-01 00:00:00

abstract：:Acute erosions of the stomach may occur in association with human spinal cord injuries. Erosion of the glandular portion of the stomach also occurs after cervical cord transection in the rat. Reports on the effects of antacids and cimetidine in the prevention of acute "stress" erosions in animals and humans have shown...

journal_title：Digestive diseases and sciences

authors： Sigman HH,Gillich A

更新日期：1982-03-01 00:00:00

abstract：:The perception that chronic hepatitis C is an asymptomatic disease contrasts with many studies that show a strong association between chronic hepatitis C, hepatocellular cancer, and fatal liver disease. In order to resolve these issues, it is logical to directly evaluate the quality of life in patients with chronic he...

journal_title：Digestive diseases and sciences

authors： Carithers RL Jr,Sugano D,Bayliss M

更新日期：1996-12-01 00:00:00

abstract：:Cholecystokinin (CCK) decreases lower esophageal sphincter pressure (LESP) in man. Cholestyramine, a nonabsorbable bile salt binding resin, stimulates endogenous CCK secretion. We have investigated the effect of oral ingestion of 16 g cholestyramine without and with infusion of the CCK receptor antagonist CR1505 (loxi...

journal_title：Digestive diseases and sciences

authors： Masclee AA,Jansen JB,Rovati LC,Lamers CB

更新日期：1993-10-01 00:00:00

abstract：:A method for isolating and characterizing intestinal lymphoid cells from colonoscopic biopsies is presented. Intraepithelial lymphocytes were separated from the lamina propria by incubation in edetic acid (EDTA) and lamina propria lymphoid cells isolated by incubation in collagenase followed by Ficoll-Hypaque density ...

journal_title：Digestive diseases and sciences

authors： Comer GM,Ramey WG,Kotler DP,Holt PR

更新日期：1986-02-01 00:00:00

abstract：:An important histologic feature of inflammatory bowel disease (IBD) is infiltration of the colonic mucosa with neutrophils. To investigate the nature of the chemotactic agents responsible for this infiltration, colonic mucosa from three normals and nine patients with inflammatory bowel disease (seven ulcerative coliti...

journal_title：Digestive diseases and sciences

authors： Lobos EA,Sharon P,Stenson WF

更新日期：1987-12-01 00:00:00

abstract：INTRODUCTION:A significant proportion of patients with Crohn's disease (CD) lose response to antibodies directed against tumor necrosis factor α (TNF). Prior TNF-antagonist failure is associated with lower rates of response to subsequent TNF-antagonist therapy. In patients failing two anti-TNF agents, a choice exists b...

journal_title：Digestive diseases and sciences

authors： Ananthakrishnan AN,Hur C,Korzenik JR

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:The preferred method for screening asymptomatic people for colorectal cancer (CRC) is colonoscopy, according to the new American guidelines. The aim of our study was to perform a meta-analysis of the prospective cohorts using total colonoscopy for screening this population for CRC. We looked for the diagnosti...

journal_title：Digestive diseases and sciences

authors： Niv Y,Hazazi R,Levi Z,Fraser G

更新日期：2008-12-01 00:00:00

abstract：:We report a case of Pseudomonas aeruginosa liver abscesses following endoscopic retrograde cholangiopancreatography (ERCP) in a patient without evidence of biliary tract disease and of any known cause of hepatic infection. Computer tomography (CT) scan was the best method of diagnosis, allowing, through guided percuta...

journal_title：Digestive diseases and sciences

authors： Davion T,Braillon A,Delamarre J,Delcenserie R,Joly JP,Capron JP

更新日期：1987-09-01 00:00:00

abstract：:While transilluminating guinea pig gastric wall, we noticed foci of irregular compression of submucosal veins and arteries, featuring parallel bands across arteries, with complete cessation of blood flow, mucosal pallor, and shrinkage of the area. Other features demonstrated that this was not due to artifactual pressu...

journal_title：Digestive diseases and sciences

authors： Piasecki CK,Thrasivoulou C

更新日期：1993-07-01 00:00:00

abstract：:An experimental model of massive (80%) small bowel resection and antiperistaltic colon interposition in between the remnant jejunum and ileum was created in rhesus monkeys. The gastrointestinal functions were assessed preoperatively and at different periods after the operation. Progressive increase in the transit time...

journal_title：Digestive diseases and sciences

authors： Sidhu GS,Narasimharao KL,Usha Rani V,Sarkar AK,Mitra SK

更新日期：1985-05-01 00:00:00

abstract：:Isoamylase distribution in the urine of normal individuals and patients admitted to the hospital with hyperamylasemia was determined by a wheat inhibitor mmethod and compared to results obtained by cellulose-acetate electrophoresis. We report two cases where the inhibitor ethod failed to give accurate results in urine...

journal_title：Digestive diseases and sciences

authors： Gersten M,Bank S,Lendvai S

更新日期：1983-11-01 00:00:00

abstract：:The effect on the mucosa of sodium nitrite that enters the colon from the ileum or transmucosally from the circulation is unknown. Isolated colonic mucosal cells and Roux-en-Y colostomies were used to test whether high doses of sodium nitrite (5-40 mM) had any harmful histological or inhibitory metabolic actions on th...

journal_title：Digestive diseases and sciences

authors： Roediger WE,Radcliffe BC,Deakin EJ,Nance SH

更新日期：1986-05-01 00:00:00

abstract：OBJECTIVES:Pancreas divisum (PD) as a cause of pancreatitis has been debated. In this study, we report the association of multiple gene polymorphisms on the risk of RAP in the presence of PD. DESIGN:We enrolled 687 individuals (167 IRAP, 276 ICP, and 244 unrelated healthy controls) from May 2015 to September 2016. Pat...

journal_title：Digestive diseases and sciences

authors： Talukdar R,Aslam M,Reddy DN,Nabi Z,Shava U,Ravikanth VV,Avanthi S,Govardhan B

更新日期：2020-08-04 00:00:00

abstract：:Bacterial infection remains a leading cause of mortality and morbidity for patients with cirrhosis, with hospitalization, alterations in the intestinal microbiota, and therapeutic drugs all implicated in its development. Bacterial infections also remain the most common precipitant of acute-on-chronic liver failure, wi...

journal_title：Digestive diseases and sciences

authors： Cannon MD,Martin P,Carrion AF

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Postmenopausal women have a higher risk of nonalcoholic steatohepatitis (NASH) along with an increase in age, and vitamin D deficiency occurs in some patients with NASH. AIM:We performed ovariectomy (OVX) surgery on female mice to mimic menopause, fed them a choline-deficient high-fat (CDHF) diet to induce ...

journal_title：Digestive diseases and sciences

authors： Ma L,Ishigami M,Honda T,Yokoyama S,Yamamoto K,Ishizu Y,Kuzuya T,Hayashi K,Hirooka Y,Goto H

更新日期：2019-09-01 00:00:00

abstract：:The effect of 5-hydroxytryptamine (5HT) was studied in circular and longitudinal muscle from the proximal and distal colon of New Zealand white rabbits. 5HT stimulated a dose-dependent isometric contraction of distal and proximal circular muscle that was greater than in distal longitudinal muscle (P less than 0.01). 5...

journal_title：Digestive diseases and sciences

authors： Ng WW,Jing J,Hyman PE,Snape WJ Jr

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Different factors have been associated with prolonged fluoroscopy time (FT) during endoscopic retrograde cholangiopancreatography (ERCP). AIM:We hypothesize that FT depends on both the anatomical location of the pathology managed during ERCP and the complexity of the ERCP. METHODS:Three centers participate...

journal_title：Digestive diseases and sciences

authors： Alkhatib AA,Abdel Jalil AA,Faigel DO,Pannala R,Crowell M,Harrison ME

更新日期：2015-06-01 00:00:00

abstract：:The protein ornithine decarboxylase antizyme (AZ) is inhibitory to both polyamine transport and synthesis. Experiments were performed to examine the distribution and regulation of AZ mRNA in cells of the small intestinal epithelium, a tissue exposed to high concentrations of extracellular polyamines and high levels of...

journal_title：Digestive diseases and sciences

authors： Gill JE,Christian JF,Seidel ER

更新日期：2002-07-01 00:00:00

abstract：:We have compared the [14C]triolein breath test for fat malabsorption with fecal fat excretion corrected for marker pellet recovery in 23 subjects with chronic liver disease. The breath test identified 15 of the 17 subjects with abnormal fecal fat excretion (sensitivity 88%). However, four of the six subjects with norm...

journal_title：Digestive diseases and sciences

authors： Absalom SR,Saverymuttu SH,Maxwell JD,Levin GE

更新日期：1988-05-01 00:00:00

abstract：:By using two-color immunofluorescence with fluorescein isothiocyanate (FITC) and phycoerythrin (PE)-labelled monoclonal antibodies and multiparameter flow cytometry, we investigated lamina propria lymphocyte subsets of patients with ulcerative colitis (UC) and Crohn's disease (CD). Leu-3/Leu-2 (CD4/CD8) ratio of lamin...

journal_title：Digestive diseases and sciences

authors： Senju M,Wu KC,Mahida YR,Jewell DP

更新日期：1991-10-01 00:00:00

abstract：:The effects of deoxycholic acid (DCA) on the intestinal microbiota, bile acid (BA) metabolism, and intestinal epithelium can be influenced by various factors. Depending on the specific conditions, DCA can be "bad" (proinflammatory) or "good" (anti-inflammatory). Mouse models of colitis show an increase in conjugated B...

journal_title：Digestive diseases and sciences

authors： Sitkin S,Pokrotnieks J

更新日期：2020-10-16 00:00:00

abstract：BACKGROUND:Human hepatocellular carcinoma (HCC) is one of the most common fatal cancers and an important health problem worldwide, but its mechanism is still unclear. Microtubule (MT) kinesin motor proteins orchestrate a variety of cellular processes (e.g. mitosis, motility and organelle transportation) and have been i...

journal_title：Digestive diseases and sciences

authors： Huang X,Liu F,Zhu C,Cai J,Wang H,Wang X,He S,Liu C,Yao L,Ding Z,Zhang Y,Zhang T

更新日期：2014-04-01 00:00:00

abstract：:Over a one-year period, 95 children and adolescents presenting with epigastric pain and/or vomiting, and without associated risk factors for development of peptide disease, underwent endoscopic antral biopsies for pathologic diagnosis and to detect presence of Campylobacter ss. pylori (C. pylori). Additional biopsies ...

journal_title：Digestive diseases and sciences

authors： Glassman MS,Schwarz SM,Medow MS,Beneck D,Halata M,Berezin S,Newman LJ

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Suppressive activity of recurrence by interferon-free direct-acting antivirals (DAA) is not elucidated after curative treatment of hepatocellular carcinoma (HCC). PATIENTS AND METHODS:A total of 177 patients received DAA after curative manners of HCC: 89 patients underwent DAA therapy after initial HCC trea...

journal_title：Digestive diseases and sciences

authors： Ikeda K,Kawamura Y,Kobayashi M,Kominami Y,Fujiyama S,Sezaki H,Hosaka T,Akuta N,Saitoh S,Suzuki F,Suzuki Y,Arase Y,Kumada H

更新日期：2017-10-01 00:00:00

abstract：:This study was designed to evaluate the role of 111In-labeled leukocyte imaging and fecal excretion in the assessment of inflammatory bowel disease. We compared these tests to various indices of disease activity in Crohn's disease, to Truelove's grading in ulcerative colitis, and to endoscopy, x-ray, and pathology in ...

journal_title：Digestive diseases and sciences

authors： Leddin DJ,Paterson WG,DaCosta LR,Dinda PK,Depew WT,Markotich J,McKaigney JP,Groll A,Beck IT

更新日期：1987-04-01 00:00:00

abstract：:Both increased duodenogastric reflux and chronic aspirin ingestion are associated with the development of gastric ulcers in man. Animal studies suggest aspirin increases duodenogastric reflux. Prostaglandin E2 protects gastric mucosa from the effects of many injurious agents and inhibits gastric motility, but its effe...

journal_title：Digestive diseases and sciences

authors： Dooley CP,Mello WD,Valenzuela JE

更新日期：1985-06-01 00:00:00

abstract：:Development of type 1 insulin-dependent diabetes mellitus has been recently reported in patients who underwent interferon-alpha (IFN-alpha) therapy because of chronic viral hepatitis. Furthermore IFN-alpha seems to be involved in the immunological events that lead to beta-cell destruction and development of type 1 dia...

journal_title：Digestive diseases and sciences

authors： di Cesare E,Previti M,Russo F,Brancatelli S,Ingemi MC,Scoglio R,Mazzù N,Cucinotta D,Raimondo G

更新日期：1996-08-01 00:00:00

abstract：:Consistent regression of intestinal metaplasia in Barrett's esophagus has not been achieved with medical or surgical interventions. In this case report, a patient with Barrett's esophagus of stable length had half the circumference of the Barrett's epithelium ablated with laser therapy while on a high-dose proton-pump...

journal_title：Digestive diseases and sciences

authors： Sampliner RE,Hixson LJ,Fennerty MB,Garewal HS

更新日期：1993-02-01 00:00:00

abstract：:In recent years, three-dimensional (3-D) printing technology has become a standard tool that is used in several medical applications such as education, surgical training simulation and planning, and doctor-patient communication. Although liver surgery is ideally complemented by the use of preoperative 3-D-printed mode...

journal_title：Digestive diseases and sciences

authors： Larghi Laureiro Z,Novelli S,Lai Q,Mennini G,D'andrea V,Gaudenzi P,Marinozzi F,Engelmann C,Mookarje R,Raptis D,Rossi M,Jalan R

更新日期：2020-08-01 00:00:00