Health assessment for chronic HCV infection: results of quality of life.

abstract：:Opioids, both endogenous and exogenous, have been shown to exert a modulating influence on many gastrointestinal functions. Animal studies suggest an inhibitory role for opioids in the control of pancreatic secretion, which may be exerted through their inhibitory effect on acetylcholine release from intramural neurons...

journal_title：Digestive diseases and sciences

authors： Dooley CP,Saad C,Valenzuela JE

更新日期：1988-05-01 00:00:00

abstract：:Growth factors, such as epidermal growth factor (EGF), are known to protect upper gut mucosa against irritants and to enhance healing of ulcerative lesions in animal models. A number of salivary growth factors are found in human saliva. The aim of this study was to determine if salivary growth factors and cytokines ar...

journal_title：Digestive diseases and sciences

authors： Kongara K,Varilek G,Soffer EE

更新日期：2001-03-01 00:00:00

abstract：:The efficacy of comaruman CP, a pectin of marsh cinquefoil Comarum palustre L., was investigated using a model of acetic acid-induced colitis in mice. Mice were administered comaruman CP orally 2 days prior to rectal injection of 5% acetic acid and examined for colonic damage 24 hr later. Colonic inflammation was char...

journal_title：Digestive diseases and sciences

authors： Popov SV,Ovodova RG,Markov PA,Nikitina IR,Ovodov YS

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Whether addition of prokinetics to proton pump inhibitors improves esophageal peristalsis and symptoms in patients with gastroesophageal reflux disease (GERD) remains unknown. AIM:We evaluated the effect of mosapride, a 5-HT4 agonist, and PPI cotherapy in patients with GERD on esophageal motility using high...

journal_title：Digestive diseases and sciences

authors： Cho YK,Choi MG,Park EY,Lim CH,Kim JS,Park JM,Lee IS,Kim SW,Choi KY

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND AND AIMS:The Chronic Hepatitis Cohort Study (CHeCS) is a longitudinal observational study of risks and benefits of treatments and care in patients with chronic hepatitis B (HBV) and C (HCV) infection from four US health systems. We hypothesized that comparative effectiveness methods-including a centralized d...

journal_title：Digestive diseases and sciences

authors： Lu M,Rupp LB,Moorman AC,Li J,Zhang T,Lamerato LE,Holmberg SD,Spradling PR,Teshale EH,Vijayadeva V,Boscarino JA,Schmidt MA,Nerenz DR,Gordon SC

更新日期：2014-12-01 00:00:00

abstract：:Plasma lipids, apoprotein A-I and B in serum and in lipoprotein fractions (VLDL + LDL, HDL2, and HDL3) obtained by preparative ultracentrifugation, as well as postheparin lipoprotein lipase activity (H-TGL and LPL) were evaluated in 17 subjects with primary biliary cirrhosis (stage II and III) subdivided into two grou...

journal_title：Digestive diseases and sciences

authors： Baldo-Enzi G,Baiocchi MR,Grotto M,Floreani AR,Zagolin M,Chiaramonte M,Cera F,Fellin R

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:The relation of gastrointestinal (GI) complaints to IgE-mediated allergy is not well understood. Increased numbers of "IgE-armed" mast cells have been observed in duodenal mucosa of patients with functional GI complaints. AIMS:To explore whether total IgE and atopic sensitization were associated with functi...

journal_title：Digestive diseases and sciences

authors： Vara EJ,Svanes C,Skorge TD,Berstad A,Florvaag E,Jarvis D,Omenaas E,Waatevik M,Johannessen A,Lied GA

更新日期：2016-01-01 00:00:00

abstract：:The effects of ecabet sodium (ecabet), 12-sulfodehydroabietic acid monosodium salt, on gastric mucin biosynthesis in rat antrum were compared with those in the corpus. Intragastric administration of ecabet significantly increased [3H]glucosamine incorporation into antral mucin as well as into corpus mucin during five ...

journal_title：Digestive diseases and sciences

authors： Ichikawa T,Ishihara K,Hayashida H,Hiruma H,Saigenji K,Hotta K

更新日期：2000-03-01 00:00:00

abstract：:The aim of this study was to assess the potential of leflunomide, an immunosuppressant in rheumatoid arthritis, as a second-line immunosuppression treatment of patients with Crohn's disease refractory or intolerant to azathioprine. The study cohort consisted of 24 patients. The primary end point was steroid-free remis...

journal_title：Digestive diseases and sciences

authors： Holtmann MH,Gerts AL,Weinman A,Galle PR,Neurath MF

更新日期：2008-04-01 00:00:00

abstract：:Esophageal diverticula can cause significant symptoms and affect the quality of life. There has been recent interest in the use of peroral endoscopic myotomy in the management of esophageal diverticula (D-POEM). In this meta-analysis, we have evaluated the efficacy and safety of D-POEM in the management of esophageal ...

journal_title：Digestive diseases and sciences

authors： Kamal F,Khan MA,Lee-Smith W,Sharma S,Marella HK,Iqbal U,Mcdonough S,Aslam A,Ismail MK,Tombazzi C,Adler DG

更新日期：2020-10-29 00:00:00

abstract：BACKGROUND:Both colorectal neoplasms and atherosclerosis can be induced by common visceral fat accumulation. However, the association between these diseases at the advanced stage, colorectal cancer and cardiovascular/cerebrovascular diseases, has not been elucidated. AIMS:This study aimed to investigate the associatio...

journal_title：Digestive diseases and sciences

authors： Yamaji Y,Yasunaga H,Hirata Y,Yamada A,Yoshida S,Horiguchi H,Fushimi K,Koike K

更新日期：2016-06-01 00:00:00

abstract：PURPOSE:In previous studies the NFKBIA 3'UTR (untranslated region) AA genotype was associated with Crohn's disease (CD), while the NFKB1-94ins/delATTG mutation increased the risk for ulcerative colitis (UC). The aim of our study was to investigate these two polymorphisms and patients' response to medical therapy and/or...

journal_title：Digestive diseases and sciences

authors： Szamosi T,Lakatos PL,Hungarian IBD Study Group.,Szilvasi A,Lakatos L,Kovacs A,Molnar T,Altorjay I,Papp M,Szabo O,Satori A,Tulassay Z,Miheller P,Horvath HC,Papp J,Tordai A,Andrikovics H

更新日期：2009-02-01 00:00:00

abstract：:Plasma pancreatic polypeptide (PP) responses to food, secretin (1 CU/kg, intravenous) and bombesin (60 pmol/kg/20 min intravenous) were compared in 14 normal subjects and in 17 patients with chronic pancreatitis and pancreatic insufficiency. Basal plasma PP concentrations were significantly higher in normal subjects t...

journal_title：Digestive diseases and sciences

authors： Lamers CB,Diemel CM,Jansen JB

更新日期：1984-02-01 00:00:00

abstract：:Abnormalities in the gastric pacemaker potentials occur in patients with impaired gastric emptying. It is unclear if treatment effects the underlying rhythm or if normalization of dysrhythmias is important. We examined the effect of cisapride using surface electrogastrograms and radionuclide gastric emptying studies o...

journal_title：Digestive diseases and sciences

authors： Rothstein RD,Alavi A,Reynolds JC

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma is a major type of liver cancer with poor prognosis. AIM:The aim of the study was to determine the prognostic significance of plasma interleukin-35 level in hepatocellular carcinoma. METHODS:A total of 153 hepatocellular carcinoma patients and 153 healthy controls were enrolled. Bl...

journal_title：Digestive diseases and sciences

authors： Qiu X,Wang X,Song Y,Chen L

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Endoscopic treatment is effective in the treatment of patients with bile duct injury after cholecystectomy. We aimed to investigate the long-term results of endoscopic treatment, factors predicting the recurrence of the stricture, and to determine the optimal endoscopic treatment. METHODS:The study...

journal_title：Digestive diseases and sciences

authors： Parlak E,Dişibeyaz S,Ödemiş B,Köksal AŞ,Küçükay F,Şaşmaz N,Şahin B

更新日期：2015-06-01 00:00:00

abstract：:Using northern blot analysis and immunohistochemistry, we assessed the expression and distribution of human epidermal growth factor receptor-1 (HER-1), HER-2, and HER-3 in pancreatic tissues obtained from patients with acute pancreatitis (AP). Overall, HER-1, HER-2, and HER-3 mRNA levels were similar in the normal pan...

journal_title：Digestive diseases and sciences

authors： Ebert M,Friess H,Büchler MW,Korc M

更新日期：1995-10-01 00:00:00

abstract：:Our aim was to investigate the role of renal colic, a clinical condition characterized by excruciating pain, in the etiopathogenesis of irritable bowel syndrome (IBS). Two groups of patients were enrolled in the study. Group I consisted of 59 patients (33 male and 26 female) with a median age of 41.9 (18 to 58) years....

journal_title：Digestive diseases and sciences

authors： Erdem E,Akbay E,Sezgin O,Doruk E,Canpolat B,Cayan S

更新日期：2005-03-01 00:00:00

abstract：:The mechanisms of pentagastrin-induced gastric mucosal blood flow (GMBF) response were investigated in anesthetized rats. A rat stomach was mounted on an ex vivo chamber, perfused with saline, and GMBF was measured by a laser Doppler flowmetry simultaneously with acid secretion. Pentagastrin infused intravenously prod...

journal_title：Digestive diseases and sciences

authors： Kato S,Okabe S,Takeuchi K

更新日期：1996-03-01 00:00:00

abstract：UNLABELLED:Recent evidence suggests a role for gut bacteria and antibiotics in the pathophysiology and treatment of irritable bowel syndrome (IBS), respectively. While the benefits of the antibiotic rifaximin have demonstrated efficacy and durable improvement in symptoms over 3 months, the long-term need for retreatmen...

journal_title：Digestive diseases and sciences

authors： Pimentel M,Morales W,Chua K,Barlow G,Weitsman S,Kim G,Amichai MM,Pokkunuri V,Rook E,Mathur R,Marsh Z

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:The pathogenesis and treatment of ulcerative colitis remain poorly understood. The aim of the present study is to investigate the effects of black cumin (Nigella sativa) oil on rats with colitis. METHODS:Experimental colitis was induced with 1 mL trinitrobenzene sulfonic acid (TNBS) in 40% ethanol by intrac...

journal_title：Digestive diseases and sciences

authors： Isik F,Tunali Akbay T,Yarat A,Genc Z,Pisiriciler R,Caliskan-Ak E,Cetinel S,Altıntas A,Sener G

更新日期：2011-03-01 00:00:00

abstract：:To ascertain how elevation of the head of the bed, bethanechol, and antacid foam tablets affect gastroesophageal reflux, we used prolonged intraesophageal pH monitoring in 55 symptomatic patients. Acid exposure was separated into reflux frequency and esophageal acid clearance time and recorded during the day in the up...

journal_title：Digestive diseases and sciences

authors： Johnson LF,DeMeester TR

更新日期：1981-08-01 00:00:00

abstract：:Impaired gallbladder emptying is one of the various factors suggested to be involved in the pathogenesis of gallstones. The present study was undertaken to determine whether gallbladder emptying, endogenous cholecystokinin (CCK) secretion, or their interrelation is altered in patients with gallstones. After intraduode...

journal_title：Digestive diseases and sciences

authors： Masclee AA,Jansen JB,Driessen WM,Geuskens LM,Lamers CB

更新日期：1989-03-01 00:00:00

abstract：:Despite progress in therapeutic approaches for the elimination of hepatitis C, chronic hepatitis C virus infection remains an important cause of liver disease. Therapeutic intervention with the currently available interferon-based treatment regimens is quite successful, but treatment is difficult to tolerate and is co...

journal_title：Digestive diseases and sciences

authors： Davis GL,Krawczynski K,Szabo G

更新日期：2007-04-01 00:00:00

abstract：:Orocecal transit time was determined by the lactulose hydrogen breath test in nine healthy volunteers after administration of placebo, loperamide (16 mg per os), and loperamide (16 mg per os) followed by oral naloxone at doses of 16 and 32 mg. The four tests were performed in double-blind conditions and in random sequ...

journal_title：Digestive diseases and sciences

authors： Basilisco G,Camboni G,Bozzani A,Paravicini M,Bianchi PA

更新日期：1987-08-01 00:00:00

abstract：AIMS:To determine whether temporary fecal diversion for refractory colonic and/or perianal Crohn's disease can lead to clinical remission and restoration of intestinal continuity after optimization of medical therapy. METHODS:We retrospectively reviewed our prospectively maintained database of patients treated at the ...

journal_title：Digestive diseases and sciences

authors： Bafford AC,Latushko A,Hansraj N,Jambaulikar G,Ghazi LJ

更新日期：2017-08-01 00:00:00

abstract：:Some patients referred for esophagogastroduodenoscopy (EGD) to evaluate symptoms of dysphagia have normal endoscopies. How best to manage these patients is unclear. We reviewed our experience with empiric esophageal dilation in this setting. Over a five-year period, 40 consecutive patients with esophageal dysphagia an...

journal_title：Digestive diseases and sciences

authors： Marshall JB,Chowdhury TA

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:Progressive hepatic fibrosis with development of cirrhosis is a feature of almost all chronic liver diseases. AIMS:We assessed the performance of Fibroscan in patients with chronic viral hepatitis, and in comparison with and combined with several surrogate serum markers for predicting cirrhosis. METHODS:In...

journal_title：Digestive diseases and sciences

authors： Lee MH,Cheong JY,Um SH,Seo YS,Kim DJ,Hwang SG,Yang JM,Han KH,Cho SW

更新日期：2010-12-01 00:00:00

abstract：:The gut smooth muscle in the intact conscious state exhibits three distinct types of contractions: rhythmic phasic contractions, tone, and ultrapropulsive contractions. The motility functions of these contractions differ markedly. The phasic contractions mix and propel the ingested food in an orderly fashion so that t...

journal_title：Digestive diseases and sciences

authors： Sarna SK

更新日期：1999-08-01 00:00:00

abstract：:Patients with symptomatic cholelithiasis who represent higher than normal surgical risks may be the most suitable candidates for medical dissolution of gallstones. Chenodeoxycholic acid was given to 97 patients in a dosage of 15 mg/kg of body weight per day for a period of two years. Complete gallstone dissolution occ...

journal_title：Digestive diseases and sciences

authors： Tangedahl T,Carey WD,Ferguson DR,Forsythe S,Williams M,Paradis K,Hightower NC

更新日期：1983-06-01 00:00:00