Salivary growth factors and cytokines are not deficient in patients with gastroesophageal reflux disease or Barrett's esophagus.

abstract：:Epidemiologic data have shown that cholecystectomy is associated with a moderately increased risk of esophageal adenocarcinoma. The study objective was to evaluate the role of refluxed bile. A total of 696 patients with upper gastrointestinal symptoms were included in the study, of whom 55 had a history of cholecystec...

journal_title：Digestive diseases and sciences

authors： Fein M,Bueter M,Sailer M,Fuchs KH

更新日期：2008-05-01 00:00:00

abstract：:We evaluated the sequence diversity of the hypervariable region 1 (HVR1) of hepatitis C virus (HCV) in HCV-infected patients in whom the mode of transmission is unknown. The sequence diversity of HVR1 in 26 Japanese patients with chronic HCV infection of unknown mode of transmission (UT) was compared with 17 patients ...

journal_title：Digestive diseases and sciences

authors： Toyoda H,Fukuda Y,Hayakawa T,Kumada T,Nakano S,Takamatsu J,Saito H

更新日期：1999-10-01 00:00:00

abstract：:Nos2 knockout mice were compared to wild-type mice for susceptibility to colitis in response to a diet supplemented with deoxycholate, a bile acid increased in the colon of individuals on a high-fat diet. Wild-type mice fed a fat-related diet, supplemented with 0.2% DOC, develop colonic inflammation associated with in...

journal_title：Digestive diseases and sciences

authors： Bernstein H,Holubec H,Bernstein C,Ignatenko NA,Gerner E,Dvorak K,Besselsen D,Blohm-Mangone KA,Padilla-Torres J,Dvorakova B,Garewal H,Payne CM

更新日期：2007-03-01 00:00:00

abstract：:The gut microbiota is a vast ensemble of microorganisms inhabiting the mammalian gastrointestinal tract that can impact physiologic and pathologic processes. However, our understanding of the underlying mechanism for the dynamic interaction between host and gut microbiota is still in its infancy. The highly evolved ep...

journal_title：Digestive diseases and sciences

authors： Ye J,Wu W,Li Y,Li L

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:According to the Japanese Esophageal Society (JES) guidelines, risk factors for lymph node (LN) metastasis in the muscularis mucosa (MM)/submucosa to a depth of up to 200 μm (SM1) in cases of esophageal squamous cell carcinomas (ESCCs) include the presence of lymphatic invasion (ly), venous invasion (v), inf...

journal_title：Digestive diseases and sciences

authors： Mizumoto T,Hiyama T,Oka S,Yorita N,Kuroki K,Kurihara M,Yoshifuku Y,Sanomura Y,Urabe Y,Murakami Y,Arihiro K,Tanaka S,Chayama K

更新日期：2018-06-01 00:00:00

abstract：:The purpose of this study was to use simultaneous anal manometry and high-frequency endoluminal ultrasonography (EUS) to determine the relationship between resting anal pressure and cross-sectional area of the internal and external anal sphincters. Eleven normal subjects underwent simultaneous anal EUS and manometry u...

journal_title：Digestive diseases and sciences

authors： Wong RF,Bonapace ES Jr,Chung CY,Liu JB,Parkman HP,Miller LS

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVE:To compare the Rosemont criteria, which are graded features chosen by experts in 2007, versus the conventional criteria, which require ≥ 3-5 of the 9 features that are "counted as equal," for the diagnosis of chronic pancreatitis by EUS. METHODS:This is a retrospective cohort study. EUS examinations were sco...

journal_title：Digestive diseases and sciences

authors： D'Souza SL,Anderson MA,Korsnes SJ,Elmunzer BJ,Piraka C,Menees S,Wamsteker EJ,Kwon RS,Scheiman JM,Elta GH

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Computed tomography (CT) and magnetic resonance (MR) enterography are now widely used to diagnose and monitor Crohn's disease. AIM:We sought to assess the use of enterography for management of inflammatory bowel disease (IBD) in our medical center. METHODS:We performed a retrospective review of all patient...

journal_title：Digestive diseases and sciences

authors： Patel NS,Pola S,Muralimohan R,Zou GY,Santillan C,Patel D,Levesque BG,Sandborn WJ

更新日期：2014-04-01 00:00:00

abstract：:We report a case of documented transient segmental aperistalsis of the distal esophagus following an accidental electrical injury. There are no other reports in the literature demonstrating this phenomenon. A review of gastrointestinal injury secondary to electrical injury is presented. ...

journal_title：Digestive diseases and sciences

authors： Rubin BM,Doman DB,Goldberg HJ,Golding MI

更新日期：1998-09-01 00:00:00

abstract：:A previous study showed that supine gastroesophageal reflux occurs mainly in the early nighttime period and is greater if the patient retires within 2 hr of a meal. We analyzed 306 consecutive esophageal pH studies between January and July 2003. Ninety-two patients had abnormal supine reflux. The recumbent period was ...

journal_title：Digestive diseases and sciences

authors： King AL,Baburajan B,Wong T,Anggiansah R,Anggiansah A

更新日期：2007-10-01 00:00:00

abstract：:The possible role of Saccharomyces boulardii, a nonpathogenic yeast with beneficial effects on the human intestine, in the maintenance treatment of Crohn's disease has been evaluated. Thirty-two patients with Crohn's disease in clinical remission (CDAI < 150) were randomly treated for six months with either mesalamine...

journal_title：Digestive diseases and sciences

authors： Guslandi M,Mezzi G,Sorghi M,Testoni PA

更新日期：2000-07-01 00:00:00

abstract：:Our aims were to measure antral axial forces in patients with suspected upper gut dysmotilities and to compare the number of antral contractions detected by an axial force catheter and by manometric sensors in the distal antrum and pylorus. Fifteen patients (2 men, 13 women; mean age 42 years) underwent studies for 3 ...

journal_title：Digestive diseases and sciences

authors： Surrenti E,Camilleri M,Kammer PP,Prather CM,Schei AJ,Hanson RB

更新日期：1996-04-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) is present in up to 75% of patients with chronic refractory ear, nose, and throat (ENT) symptoms, and proton pump inhibitor (PPI) therapy induces symptom relief in the majority of these patients. It has been suggested that endoscopic findings and quantification of esophageal acid...

journal_title：Digestive diseases and sciences

authors： Poelmans J,Feenstra L,Tack J

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:Partially covered metal stents (PCMS) have been increasingly used for both malignant and benign biliary indications. This study reports their complications and subsequent management. METHODS:Over 5 years, all patients receiving biliary PCMS were followed prospectively until stent-related dysfunction or deat...

journal_title：Digestive diseases and sciences

authors： Ho H,Mahajan A,Gosain S,Jain A,Brock A,Rehan ME,Ellen K,Shami VM,Kahaleh M

更新日期：2010-02-01 00:00:00

abstract：:The aim of the study was to determine inter- and intrapatient variation of Helicobacter pylori strains based on genomic fingerprinting and cagA (cytotoxin-associated gene A) status. Ten bacterial colonies from each of 10 patients with gastric cancer (GC), 10 with duodenal ulcer (DU), and 10 with gastritis (GI) were us...

journal_title：Digestive diseases and sciences

authors： Enroth H,Nyrén O,Engstrand L

更新日期：1999-01-01 00:00:00

abstract：:Twenty-eight patients with delayed gastric emptying as measured by an abnormal barium "burger" were treated with metoclopramide in a randomized, double-blind fashion. Five had diabetic gastroparesis, four had undergone vagotomy and pyloroplasty, and 19 were idiopathic. Patients received either metoclopramide or placeb...

journal_title：Digestive diseases and sciences

authors： Perkel MS,Moore C,Hersh T,Davidson ED

更新日期：1979-09-01 00:00:00

abstract：:The diagnostic accuracy of two different methods of sectioning rectal biopsies was evaluated prospectively. The frequency of focal and diffuse findings in more than 80 serial sections from a limited portion of the well-oriented areas of 74 biopsies was compared with that found in three or more step sections distribute...

journal_title：Digestive diseases and sciences

authors： Surawicz CM

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND:Sigmoid volvulus is a common condition in elderly patients with elongated colons. Although endoscopic de-torsion is effective as the primary treatment of sigmoid volvulus, elective surgery is recommended because of the high risk of recurrence and high mortality rate. AIM:The aim of this study was to determi...

journal_title：Digestive diseases and sciences

authors： Kusunoki R,Fujishiro H,Miyake T,Suemitsu S,Kataoka M,Fujiwara A,Tsukano K,Kotani S,Yamanouchi S,Aimi M,Tanaka M,Miyaoka Y,Kohge N,Imaoka T,Yuasa K,Kodama K,Ishihara S,Kinoshita Y

更新日期：2020-05-14 00:00:00

abstract：:Omentum was shown to exhibit angiogenic activity, but its role in healing of chronic gastric ulcers is unknown. This study was designed to compare the effects of omentum and basic fibroblast growth factor (bFGF), a potent angiogenic factor, on healing of chronic gastric ulcers in rats. Several series of rats with gast...

journal_title：Digestive diseases and sciences

authors： Konturek SJ,Brzozowski T,Majka I,Pawlik W,Stachura J

更新日期：1994-05-01 00:00:00

abstract：:In our hospital within one year two patients with Crohn's disease were seen who developed an acute myelocytic leukemia. A review of the literature reveals eight previously reported patients with both Crohn's disease and leukemia. Six of the reported 10 patients have had acute myelocytic leukemia and, interestingly, th...

journal_title：Digestive diseases and sciences

authors： Halme L,von Knorring J,Elonen E

更新日期：1990-12-01 00:00:00

abstract：AIM:To investigate whether a diagnostic delay is associated with a poor outcome in Crohn's disease (CD). METHODS:Medical and socioeconomic characteristics as well as medications and need for surgery of consecutive CD adults patients followed in three referral centers were prospectively recorded using an electronic dat...

journal_title：Digestive diseases and sciences

authors： Nahon S,Lahmek P,Paupard T,Lesgourgues B,Chaussade S,Peyrin-Biroulet L,Abitbol V

更新日期：2016-11-01 00:00:00

abstract：:The impact of treatment on progression of fibrosis in autoimmune hepatitis (AIH) is unknown. We assessed the changes in liver fibrosis before and after treatment among these patients. Nineteen AIH patients who had paired liver biopsies were studied. Of these, seven had been treated with 6 months of cyclosporine A and ...

journal_title：Digestive diseases and sciences

authors： Mohamadnejad M,Malekzadeh R,Nasseri-Moghaddam S,Hagh-Azali S,Rakhshani N,Tavangar SM,Sedaghat M,Alimohamadi SM

更新日期：2005-03-01 00:00:00

abstract：:Endoscopic biopsies are being increasingly utilized to investigate cytokine profiles in normal and diseased intestine. To evaluate the adequacy of mucosal biopsies as a source of cytokine-specific mRNA, we measured their content of interleukin-1 beta (IL-1 beta) and interleukin-2 (IL-2) mRNA by reverse transcription-p...

journal_title：Digestive diseases and sciences

authors： Fukushima K,West G,Fiocchi C

更新日期：1995-07-01 00:00:00

abstract：:A 36-year-old female with a six-year history of Crohn's disease of the anus and colon was found to have in situ cloacogenic carcinoma of the anus after having undergone total proctocolectomy for massive bleeding. This case further supports the association between Crohn's disease of the gastrointestinal tract and its p...

journal_title：Digestive diseases and sciences

authors： Daly JJ,Madrazo A

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND:The endoscopic detection of esophageal cancer is suboptimal in both patients referred with dyspeptic symptoms and those enrolled in Barrett's surveillance programs. MCM5 expression in cells collected from gastric fluid may be correlated with the presence of dysplasia or adenocarcinoma. Analysis of this bioma...

journal_title：Digestive diseases and sciences

authors： Everson M,Magee C,Alzoubaidi D,Brogden S,Graham D,Lovat LB,Novelli M,Haidry R

更新日期：2019-10-01 00:00:00

abstract：:When radiolabeled 1,25-dihydroxyvitamin D3 is added to the perfusion medium of a rat liver perfusion system, a polar metabolite of 1,25-dihydroxyvitamin D3 is formed in the liver and excreted in the bile. Addition of radiolabeled 1,25-dihydroxyvitamin D3 to the perfusion medium without a liver in the circuit results i...

journal_title：Digestive diseases and sciences

authors： Kumar R,Nagubandi S,Londowski JM

更新日期：1981-03-01 00:00:00

abstract：:Cytomegalovirus (CMV) inclusions were found at colonic perforation sites in three patients with clinical settings suggesting a compromised immunologic status. This could be interpreted as: (1) CMV was an etiologic agent in these perforations; or (2) CMV was an opportunistic superinfection in areas of preexisting infla...

journal_title：Digestive diseases and sciences

authors： Goodman ZD,Boitnott JK,Yardley JH

更新日期：1979-05-01 00:00:00

abstract：:The 1993 Milwaukee Cryptosporidium outbreak posed several questions regarding appropriate management and prognosis of inflammatory bowel disease patients acutely infected with this organism. We prospectively identified and monitored 12 patients with stable ulcerative colitis or Crohn's disease who suffered abrupt clin...

journal_title：Digestive diseases and sciences

authors： Manthey MW,Ross AB,Soergel KH

更新日期：1997-08-01 00:00:00

abstract：:Suspected risk factors for adenocarcinoma of the small bowel in Crohn's disease include surgically excluded small bowel loops, chronic fistulous disease, and male sex. Review of all seven University of Chicago cases failed to confirm any suspected risk factor. A case-control study was performed to identify possible al...

journal_title：Digestive diseases and sciences

authors： Lashner BA

更新日期：1992-08-01 00:00:00

abstract：INTRODUCTION:Periampullary diverticulum (PAD) is most often asymptomatically found in elderly population. ERCP in the presence of PAD is technically challenging since the location and orientation of the ampulla could be altered. Various studies have reported differing results on the technical success and safety outcome...

journal_title：Digestive diseases and sciences

authors： Jayaraj M,Mohan BP,Dhindsa BS,Mashiana HS,Radhakrishnan G,Dhir V,Trindade AJ,Adler DG

更新日期：2019-05-01 00:00:00