Deoxycholate-induced colitis is markedly attenuated in Nos2 knockout mice in association with modulation of gene expression profiles.

abstract：:Both intracellular calcium ions and neural input are important in esophageal smooth muscle contraction. The aim of this study was to compare the effects of well-tolerated doses of the calcium-channel blocker, nifedipine (20 mg sublingually/buccally) with the anticholinergic, propantheline bromide (15 mg orally) and th...

journal_title：Digestive diseases and sciences

authors： Hongo M,Traube M,McCallum RW

更新日期：1984-04-01 00:00:00

abstract：:A primary histiocytic lymphoma arising in the esophagus and its resultant spontaneous perforation is reported in a 69-year-old female. To our knowledge esophageal perforation occurring as a complication of a primary non-Hodgkin's lymphoma of the esophagus has not been previously reported. ...

journal_title：Digestive diseases and sciences

authors： Kirsch HL,Cronin DW,Stein GN,Latour F,Herrera AF

更新日期：1983-04-01 00:00:00

abstract：:Intestinal injury 4-48 hr after cytotoxic therapy (etoposide phosphate, 100 mg/kg body weight [bw], intravenously [i.v.]) was studied in rats using ligated intestinal loops. Chromium-51 ethylenediaminetetraacetic acid ((51)Cr-EDTA) and rubidium-86 chloride ((86)RbCl) were deposited intraluminally to determine the exte...

journal_title：Digestive diseases and sciences

authors： Abel E,Ekman T,Warnhammar E,Hultborn R,Jennische E,Lange S

更新日期：2005-09-01 00:00:00

abstract：:Inadequate vegetable intake appears to increase colon cancer risk. Since genetic variation in taste influences vegetable preference, we tested associations between bitterness of 6-n-propylthiouracil (PROP), a measure of taste genetics, and number of colonic polyps, a measure of colon cancer risk, in 251 men who underw...

journal_title：Digestive diseases and sciences

authors： Basson MD,Bartoshuk LM,Dichello SZ,Panzini L,Weiffenbach JM,Duffy VB

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Irritable bowel syndrome (IBS) patients frequently complain of gas-related symptoms, and the lactulose breath test (LBT) is a test that assesses the amount of fermented gas generated by bacteria in the bowel. We aimed to assess the relationship among intestinal gas volume, LBT result, and gastrointe...

journal_title：Digestive diseases and sciences

authors： Youn YH,Park JS,Jahng JH,Lim HC,Kim JH,Pimentel M,Park H,Lee SI

更新日期：2011-07-01 00:00:00

abstract：:Gastroesophageal reflux disease (GERD) is caused by a mechanically defective lower esophageal sphincter (LES) and may be worsened by impaired esophageal peristalsis. The aim of this study was to evaluate the efficacy of medical treatment depending on the function of the LES and esophageal peristalsis. We studied 128 G...

journal_title：Digestive diseases and sciences

authors： Klaus A,Gadenstaetter M,Mühlmann G,Kirchmayr W,Profanter C,Achem SR,Wetscher GJ

更新日期：2003-09-01 00:00:00

abstract：:We have developed a breath test to measure solid gastric emptying using a standardized scrambled egg test meal (250 kcal) labeled with [14C]octanoic acid or [13C]octanoic acid. In vitro incubation studies showed that octanoic acid is a reliable marker of the solid phase. The breath test was validated in 36 subjects by...

journal_title：Digestive diseases and sciences

authors： Maes BD,Ghoos YF,Rutgeerts PJ,Hiele MI,Geypens B,Vantrappen G

更新日期：1994-12-01 00:00:00

abstract：:A previous study showed that supine gastroesophageal reflux occurs mainly in the early nighttime period and is greater if the patient retires within 2 hr of a meal. We analyzed 306 consecutive esophageal pH studies between January and July 2003. Ninety-two patients had abnormal supine reflux. The recumbent period was ...

journal_title：Digestive diseases and sciences

authors： King AL,Baburajan B,Wong T,Anggiansah R,Anggiansah A

更新日期：2007-10-01 00:00:00

abstract：:Autoimmune hepatitis (AIH) is rare in Asian countries compared to the West, and an exceptionally low prevalence was noted previously in Taiwan. Using the revised criteria of the IAIHG, 48 cases of AIH patients were diagnosed. All patients were consecutively diagnosed over a period of 5 years. Detailed medical historie...

journal_title：Digestive diseases and sciences

authors： Koay LB,Lin CY,Tsai SL,Lee C,Lin CN,Sheu MJ,Kuo HT,Sun CS

更新日期：2006-11-01 00:00:00

abstract：INTRODUCTION:Interpretation of video capsule data is time-consuming. Olympus capsule endoscopy (CE) software systems are equipped with auto-speed-adjusted and express-selected playback modes and overview function in an effort to reduce reading times. The clinical efficacy of these new playback features is unknown. Our ...

journal_title：Digestive diseases and sciences

authors： Subramanian V,Mannath J,Telakis E,Ragunath K,Hawkey CJ

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:Proton pump inhibitors (PPIs) may reduce the risk of esophageal adenocarcinoma (EAC) in patients with Barrett's esophagus. PPIs are prescribed for virtually all patients with Barrett's esophagus, irrespective of the presence of reflux symptoms, and represent a de facto chemopreventive agent in this populatio...

journal_title：Digestive diseases and sciences

authors： Sharaiha RZ,Freedberg DE,Abrams JA,Wang YC

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:The role of cannabinoids in gastrointestinal diseases is controversial and of great interest, yet their use in patients has not been critically examined. AIM:To determine the prevalence and effects of cannabis abuse on healthcare utilization, as measured by emergency department (ED) visits, in a large, tert...

journal_title：Digestive diseases and sciences

authors： Gubatan J,Staller K,Barshop K,Kuo B

更新日期：2016-07-01 00:00:00

abstract：:Little information on functional status and well-being is available in patients with functional gastrointestinal disease. We aimed to evaluate whether quality of life is poorer in patients with functional dyspepsia. A consecutive sample of 73 patients with functional dyspepsia completed a validated questionnaire prior...

journal_title：Digestive diseases and sciences

authors： Talley NJ,Weaver AL,Zinsmeister AR

更新日期：1995-03-01 00:00:00

abstract：:Calcineurin inhibitor (CI)-associated renal dysfunction has emerged as a major cause of morbidity and mortality after liver transplantation. In this retrospective study, we compared the efficacy, safety, and renal protective effect of sirolimus monotherapy (Group A; n = 26) with sirolimus in combination (Group B; n = ...

journal_title：Digestive diseases and sciences

authors： Maheshwari A,Torbenson MS,Thuluvath PJ

更新日期：2006-10-01 00:00:00

abstract：INTRODUCTION:Assessment of whole gut transit, by radio-opaque markers or scintigraphy, is used to evaluate patients with constipation for slow gastrointestinal transit. Wireless capsule motility, using the SmartPill GI monitoring system, samples and transmits intraluminal pH, pressure, and temperature data from a capsu...

journal_title：Digestive diseases and sciences

authors： Maqbool S,Parkman HP,Friedenberg FK

更新日期：2009-10-01 00:00:00

abstract：:Patients with chronic epigastric to right upper quadrant pain are often considered to have gallbladder of sphincter of Oddi dysfunction, but standard tests are nondiagnostic. In 62 consecutive patients with this compliant undergoing antroduodenal manometry, we correlated a change on duodenal motility with spasm of the...

journal_title：Digestive diseases and sciences

authors： Koussayer T,Ducker TE,Clench MH,Mathias JR

更新日期：1995-08-01 00:00:00

abstract：:The neutralizing capacity of two antacids (Alucol = A, Syntrogel = S), differing both in their composition and theoretical neutralizing capacity, was evaluated in vitro and in vivo. In vitro at pH 3.5, 1 ml of A or S neutralizes 3.9 and 1.6 meq of acid, respectively, in an aqueous solution. When tested in vivo in the ...

journal_title：Digestive diseases and sciences

authors： Berchtold P,Reinhart WH,Niederhäuser U,Koller U,Halter F

更新日期：1985-06-01 00:00:00

abstract：BACKGROUND:A possible association between nonalcoholic fatty liver disease (NAFLD) and hypothyroidism has been suggested. The recognized link between hypothyroidism and elements of the metabolic syndrome may explain this association. AIM:The purpose of this study was to determine the prevalence of hypothyroidism in a ...

journal_title：Digestive diseases and sciences

authors： Pagadala MR,Zein CO,Dasarathy S,Yerian LM,Lopez R,McCullough AJ

更新日期：2012-02-01 00:00:00

abstract：:Ethanol is a common cause of both acute and chronic pancreatitis. Studies in other organs suggest that polymorphonuclear neutrophils activated by ethanol may cause tissue injury in a variety of conditions. The aim of this study was to investigate the effects of ethanol on neutrophil extravasation in the feline pancrea...

journal_title：Digestive diseases and sciences

authors： Reber PU,Lewis MP,Patel AG,Andren-Sandberg A,Ashley SW,Reber HA

更新日期：1998-12-01 00:00:00

abstract：:Leptin is an adipocyte-derived hormone involved in the homeostasis of body composition. An imbalance in leptin regulation has been observed in patients with liver cirrhosis. We aimed to assess serum and ascitic leptin levels in a group of patients with decompensated liver cirrhosis and to evaluate the relationship of ...

journal_title：Digestive diseases and sciences

authors： Giannini E,Romagnoli P,Tenconi GL,Botta F,Malfatti F,Chiarbonello B,Mamone M,Barreca T,Testa R

更新日期：2004-02-01 00:00:00

abstract：:The present study aimed to investigate the role of nitric oxide on the oxidative damage in isolated rabbit gastric cells exposed to hypoxia-reoxygenation. Nitric oxide synthesis modulators such as L-arginine and NG-nitro-L-arginine methyl ester, a nitric oxide donor, sodium nitroprusside, and superoxide dismutase were...

journal_title：Digestive diseases and sciences

authors： Kim H,Kim KH

更新日期：1998-05-01 00:00:00

abstract：:An intravenous injection of diphenylthiocarbazone (dithizone), a zinc chelator, induces selective killing and rapid regeneration of Paneth cells, which have a large amount of zinc in their cytoplasmic granules. We examined the expression pattern of transforming growth factor (TGF) -alpha and TGF-beta1 in this regenera...

journal_title：Digestive diseases and sciences

authors： Seno H,Sawada M,Fukuzawa H,Morita Y,Takaishi S,Hiai H,Chiba T

更新日期：2001-05-01 00:00:00

abstract：:Bicyclol is a synthetic antihepatitis drug with antioxidative property. The present study was performed to investigate the effect of bicyclol on liver regeneration after partial hepatectomy in rats. Bicyclol (300 mg/kg) was given to rats subjected to 70% hepatectomy three times before operation. At 6, 24, and 48 h aft...

journal_title：Digestive diseases and sciences

authors： Yao XM,Zhao J,Li Y,Li Y

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Patients with cirrhosis are at high readmission risk. Using a large statewide database, we evaluated the effect of hospital cirrhosis-related patient volume on 30-day readmissions in patients with cirrhosis. METHODS:We conducted a retrospective study of the Healthcare Cost and Utilization Project State Inpa...

journal_title：Digestive diseases and sciences

authors： Wei M,Ford J,Li Q,Jeong D,Kwong AJ,Nguyen MH,Chang MS

更新日期：2018-09-01 00:00:00

abstract：BACKGROUND:Obesity, gastroesophageal reflux, and Barrett's esophagus have all been linked to esophageal adenocarcinoma. In addition, the decline in Helicobacter pylori (H. pylori) infection in affluent societies has also been suggested to be a major factor in the recent rise in the incidence of esophageal adenocarcinom...

journal_title：Digestive diseases and sciences

authors： Lee YY,Raj SM,Sharif SE,Salleh R,Ayub MC,Graham DY

更新日期：2011-05-01 00:00:00

abstract：INTRODUCTION:Readmission for achalasia treatment is associated with significant morbidity and cost. Factors predictive of readmission would be useful in identifying patients at risk. METHODS:We performed a retrospective study using the Nationwide Readmission Database for the year 2016 and 2017. We collected data on ho...

journal_title：Digestive diseases and sciences

authors： Gupta K,Khan A,Chalhoub J,Groudan K,Desilets D

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Given the rising epidemics of obesity and metabolic syndrome, nonalcoholic steatohepatitis (NASH) is now the most common cause of liver disease in the developed world. Effective treatment for NASH, either to reverse or prevent the progression of hepatic fibrosis, is currently lacking. AIM:To define the pred...

journal_title：Digestive diseases and sciences

authors： Glass LM,Dickson RC,Anderson JC,Suriawinata AA,Putra J,Berk BS,Toor A

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:Diarrhea, a major pathological hallmark of inflammatory bowel disease, is characterized by a significant reduction in the expression and function of key intestinal ion transporters. The adoptive naïve CD4+ T cell transfer colitis is an immune-based, chronic colitis mouse model which resembles human Crohn's d...

journal_title：Digestive diseases and sciences

authors： Jayawardena D,Tyagi S,Nazmi A,Olivares-Villagómez D,Dudeja PK

更新日期：2020-06-01 00:00:00

abstract：:The diagnosis of irritable bowel syndrome requires the exclusion of any associated organic disease: a positive diagnosis would avoid expensive and potentially dangerous diagnostic procedures. A scoring system has been proposed for positive diagnosis where more than 44 points excluded organic digestive disease. The aim...

journal_title：Digestive diseases and sciences

authors： Frigerio G,Beretta A,Orsenigo G,Tadeo G,Imperiali G,Minoli G

更新日期：1992-02-01 00:00:00

abstract：:Barrett's esophagus (BE) is a well-known premalignant condition that can be associated with the development of dysplasia and adenocarcinoma. In the past, esophagectomy was the standard treatment for patients with BE with high grade dysplasia (HGD) and early cancer (EC). However, esophagectomy is not necessarily the on...

journal_title：Digestive diseases and sciences

authors： Azarm A,Lukolic I,Shukla M,Concha-Parra R,Gress F

更新日期：2012-12-01 00:00:00