当前位置： SCI文献检索 > DIGESTIVE DISEASES AND SCIENCES期刊下所有文献 > Saccharomyces boulardii in maintenance treatment of Crohn's disease.

Saccharomyces boulardii in maintenance treatment of Crohn's disease.

Abstract：

:The possible role of Saccharomyces boulardii, a nonpathogenic yeast with beneficial effects on the human intestine, in the maintenance treatment of Crohn's disease has been evaluated. Thirty-two patients with Crohn's disease in clinical remission (CDAI < 150) were randomly treated for six months with either mesalamine 1 g three times a day or mesalamine 1 g two times a day plus a preparation of Saccharomyces boulardii 1 g daily. Clinical relapses as assessed by CDAI values were observed in 37.5% of patients receiving mesalamine alone and in 6.25% of patients in the group treated with mesalamine plus the probiotic agent. Our results suggest that Saccharomyces boulardii may represent a useful tool in the maintenance treatment of Crohn's disease. However, in view of the product's cost, further controlled studies are needed to confirm these preliminary data.

journal_name

Dig Dis Sci

journal_title

Digestive diseases and sciences

authors

Guslandi M,Mezzi G,Sorghi M,Testoni PA

doi

10.1023/a:1005588911207

subject

Has Abstract

pub_date

2000-07-01 00:00:00

pages

1462-4

issue

7

eissn

0163-2116

issn

1573-2568

journal_volume

45

pub_type

临床试验,杂志文章,随机对照试验

相关文献

DIGESTIVE DISEASES AND SCIENCES文献大全
  • Immune phenotype of children with newly diagnosed and gluten-free diet-treated celiac disease.

    abstract：BACKGROUND:Recent data suggest the involvement of both the adaptive and the innate immune system in celiac disease (CD). However, little is known about the immune phenotype of children with CD and its alteration upon dietary intervention. AIMS:We characterized the prevalence of major interacting members of the adaptiv...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-010-1363-6

    authors： Cseh Á,Vásárhelyi B,Szalay B,Molnár K,Nagy-Szakál D,Treszl A,Vannay Á,Arató A,Tulassay T,Veres G

    更新日期：2011-03-01 00:00:00

  • Early disturbance of microvascular function precedes chemotherapy-induced intestinal injury.

    abstract：:Intestinal injury 4-48 hr after cytotoxic therapy (etoposide phosphate, 100 mg/kg body weight [bw], intravenously [i.v.]) was studied in rats using ligated intestinal loops. Chromium-51 ethylenediaminetetraacetic acid ((51)Cr-EDTA) and rubidium-86 chloride ((86)RbCl) were deposited intraluminally to determine the exte...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-005-2926-9

    authors： Abel E,Ekman T,Warnhammar E,Hultborn R,Jennische E,Lange S

    更新日期：2005-09-01 00:00:00

  • PYY potently inhibits pancreatic exocrine secretion mediated through CCK-secretin-stimulated pathways but not 2-DG-stimulated pathways in awake rats.

    abstract：:Peptide YY (PYY) is an important modulator of stimulated pancreatic exocrine secretion. PYY acts proximal to the acinar cell but the exact site and mechanism of action are unknown. The aim of the present study is to determine the pathway through which PYY exerts its effect on the exocrine pancreas in awake rats under ...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1023/a:1005622227906

    authors： Deng X,Guarita DR,Wood PG,Kriess C,Whitcomb DC

    更新日期：2001-01-01 00:00:00

  • Association between H. pylori, duodenal mechanosensory thresholds, and small intestinal motility in chronic unexplained dyspepsia.

    abstract：:Alterations of small intestinal sensory thresholds and small intestinal dysmotility are associated with functional dyspepsia. Because gastric and duodenal afferents partly project to the same areas, we postulated that patients with functional dyspepsia and H. pylori infection would be characterized by lower duodenal s...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF02088548

    authors： Holtmann G,Talley NJ,Goebell H

    更新日期：1996-07-01 00:00:00

  • Rebamipide prevents indomethacin-induced gastric mucosal lesion formation by inhibiting activation of neutrophils in rats.

    abstract：:Since granulocyte elastase has been shown to be involved in the pathogenesis of gastric mucosal lesion formation induced by nonsteroidal antiinflammatory drugs, inhibition of granulocyte elastase release from neutrophils may be useful in the prevention of these lesions. The objective of this study was to determine whe...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：

    authors： Murakami K,Okajima K,Harada N,Isobe H,Okabe H

    更新日期：1998-09-01 00:00:00

  • Methionine deficiency and hepatic injury in a dietary steatohepatitis model.

    abstract：:Methionine (Meth) is an essential amino acid involved in DNA methylation and glutathione biosynthesis. We examined the effect of Meth on the development of steatohepatitis. Rats were fed (five weeks) amino acid-based Meth-choline-sufficient (A-MCS) or total deficient (MCD) diets and gavaged daily (two weeks) with vehi...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-007-9900-7

    authors： Oz HS,Chen TS,Neuman M

    更新日期：2008-03-01 00:00:00

  • Rectal administration of lipopolysaccharide and ovalbumin ameliorates acute murine colitis.

    abstract：BACKGROUND:Repeated challenges of lipopolysaccharide (LPS) could reduce the expression of proinflammatory cytokines in vitro, and oral administration of ovalbumin (OVA) induces mucosal tolerance in vivo. However, the effect of local administration of LPS and OVA on experimental colitis in vivo remains unknown. AIMS:Th...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-011-1630-1

    authors： Im JP,Ye BD,Kim JM,Jung HC,Song IS,Kim JS

    更新日期：2011-08-01 00:00:00

  • Obstructive jaundice alters LFA-1alpha expression in rat small intestine.

    abstract：:Translocation of bacteria and endotoxtin has long been documented in obstructive jaundice, and altered intestinal barrier function is considered to be one of the important mechanisms for this phenomenon. The regulation of gastrointestinal mucosal response to injury is thus of important clinical as well as biological r...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1023/a:1023737317477

    authors： Sheen-Chen SM,Chen HS,Ho HT,Sheen CC,Chen WJ,Eng HL

    更新日期：2003-06-01 00:00:00

  • Therapy for unhealed gastrocutaneous fistulas in rats as a model for analogous healing of persistent skin wounds and persistent gastric ulcers: stable gastric pentadecapeptide BPC 157, atropine, ranitidine, and omeprazole.

    abstract：OBJECTIVE:This study focused on unhealed gastrocutaneous fistulas to resolve whether standard drugs that promote healing of gastric ulcers may simultaneously have the same effect on cutaneous wounds, and corticosteroid aggravation, and to demonstrate why peptides such as BPC 157 exhibit a greater healing effect. Theref...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-008-0332-9

    authors： Skorjanec S,Dolovski Z,Kocman I,Brcic L,Blagaic Boban A,Batelja L,Coric M,Sever M,Klicek R,Berkopic L,Radic B,Drmic D,Kolenc D,Ilic S,Cesarec V,Tonkic A,Zoricic I,Mise S,Staresinic M,Ivica M,Lovric Bencic M,Anic

    更新日期：2009-01-01 00:00:00

  • Effect of nitric oxide on gallbladder motility in patients with acalculous biliary pain: a cholescintigraphic study.

    abstract：:The aim of the present study was to evaluate the influence of the exogenous nitric oxide donor glyceryl trinitrate on cerulein-induced gallbladder contraction in patients with acalculous biliary pain. Quantitative hepatobiliary scintigraphy was performed on 33 patients. From the 60th min cerulein (1 ng/kg body wt/min ...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1023/a:1019648123515

    authors： Madácsy L,Velosy B,Szepes A,Szilvássy Z,Pávics L,Csernay L,Lonovics J

    更新日期：2002-09-01 00:00:00

  • Oncogenic transformation of normal enterocytes by overexpression of cyclin D1.

    abstract：:Cyclin D1 plays an important role in the multi-step process of gastrointestinal tumorigenesis. We hypothesize that normal enterocytes over-expressing cyclin D1 will demonstrate a transformed phenotype. The nontumorigenic intestinal epithelial cell line, IEC-18, was transfected with the vector pMV7-CCND1, encoding cycl...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1023/a:1024138605802

    authors： Kazanov D,Shapira I,Pick M,Kolker O,Liberman E,Deutsch V,Strier L,Dvory-Sobol H,Kunik T,Arber N

    更新日期：2003-07-01 00:00:00

  • Short-term effects of bile diversion on postgastrectomy gastric histology.

    abstract：:Twelve partially gastrectomized subjects who have consecutively undergone total biliary diversion for severe bilious vomiting were studied before and after operation in order to assess the effects of surgery on gastric histology and enterogastric reflux. Before and six months after operation, the following protocol wa...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF01536682

    authors： Bechi P,Amorosi A,Mazzanti R,Buccarelli A,Pantalone D,Cortesini C

    更新日期：1988-10-01 00:00:00

  • Novel classification and pathogenetic analysis of hypoganglionosis and adult-onset Hirschsprung's disease.

    abstract：BACKGROUND AND AIMS:Researchers have not clearly described the clinical and pathogenetic features of hypoganglionosis and adult-onset Hirschsprung's disease, which cause pseudo-obstruction or intractable constipation. We conducted this study to explore these features of hypoganglionosis and adult-onset Hirschsprung's d...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-010-1522-9

    authors： Do MY,Myung SJ,Park HJ,Chung JW,Kim IW,Lee SM,Yu CS,Lee HK,Lee JK,Park YS,Jang SJ,Kim HJ,Ye BD,Byeon JS,Yang SK,Kim JH

    更新日期：2011-06-01 00:00:00

  • Liver histology changes in nonalcoholic steatohepatitis after one year of treatment with probucol.

    abstract：BACKGROUND:Probucol, a lipid-lowering agent with antioxidant effects, is effective in normalizing liver enzymes in patients with nonalcoholic steatohepatitis (NASH). We studied changes in the liver histology of patients with NASH after use of probucol for one year. METHODS:Ten patients with biopsy-proven NASH were inc...

    journal_title：Digestive diseases and sciences

    pub_type： 临床试验,杂志文章

    doi：10.1007/s10620-007-0109-6

    authors： Merat S,Aduli M,Kazemi R,Sotoudeh M,Sedighi N,Sohrabi M,Malekzadeh R

    更新日期：2008-08-01 00:00:00

  • Peritoneal sarcoidosis. An unrecognized cause of sclerosing peritonitis.

    abstract：:In a Caucasian woman with a history of ocular and pulmonary sarcoidosis, the occurrence of sclerosing peritonitis with exudative ascites but without any of the well-known causes of this syndrome prompts us to consider that sclerosing peritonitis is a manifestation of sarcoidosis. The dramatic improvement that occurred...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF01299875

    authors： Ngô Y,Messing B,Marteau P,Nouël O,Pasquiou A,Lavergne A,Rambaud JC

    更新日期：1992-11-01 00:00:00

  • Campylobacter pylori is not associated with gastroparesis.

    abstract：:There is a high incidence of Campylobacter pylori in the gastric mucosa of patients with duodenal ulcer, gastric ulcer, and nonulcer dyspepsia. Factors that lead to development of this infection are unknown. We hypothesized that delayed solid-phase gastric emptying, a condition characterized by antral stasis, might pr...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF01540043

    authors： Barnett JL,Behler EM,Appelman HD,Elta GH

    更新日期：1989-11-01 00:00:00

  • Transpancreatic Sphincterotomy Is Effective and Safe in Expert Hands on the Short Term.

    abstract：:In cases of difficult biliary cannulation, transpancreatic sphincterotomy (TPS) can be an alternative approach of biliary access. However, its success and safety profile have not been studied in detail. A systematic review and meta-analysis were performed to study the overall cannulation success and adverse events of ...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章,meta分析

    doi：10.1007/s10620-019-05640-4

    authors： Pécsi D,Farkas N,Hegyi P,Varjú P,Szakács Z,Fábián A,Varga G,Rakonczay Z Jr,Bálint ER,Erőss B,Czimmer J,Szepes Z,Vincze Á

    更新日期：2019-09-01 00:00:00

  • Hepatopulmonary syndrome in noncirrhotic portal hypertensive patients.

    abstract：:Hepatopulmonary syndrome has yet not been sufficiently assessed in noncirrhotic portal hypertension. The prevalence of hepatopulmonary syndrome was determined in 31 consecutive patients with noncirrhotic portal hypertension (19 idiopathic portal hypertension, 7 portal vein thrombosis, 5 congenital hepatic fibrosis) an...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1023/a:1022549018807

    authors： Kaymakoglu S,Kahraman T,Kudat H,Demir K,Cakaloglu Y,Adalet I,Dincer D,Besisik F,Boztas G,Sözen AB,Mungan Z,Okten A

    更新日期：2003-03-01 00:00:00

  • Recalibrating the Child-Turcotte-Pugh Score to Improve Prediction of Transplant-Free Survival in Patients with Cirrhosis.

    abstract：BACKGROUND:The Child-Turcotte-Pugh (CTP) score is a widely used and validated predictor of long-term survival in cirrhosis. However, the cutpoints for stratifying laboratory variables in CTP have never been validated. OBJECTIVE:The objective of this study was to identify evidence-based cutpoints for the CTP laboratory...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-016-4239-6

    authors： Kaplan DE,Dai F,Skanderson M,Aytaman A,Baytarian M,D'Addeo K,Fox R,Hunt K,Knott A,Mehta R,Pedrosa M,Pocha C,Valderrama A,Taddei T,VOCAL Study Group.

    更新日期：2016-11-01 00:00:00

  • False negative fecal occult blood test may be associated with increased mortality from colorectal cancer.

    abstract：BACKGROUND:Fecal Occult Blood Test (FOBT) is an accepted screening test for colorectal cancer (CRC). It has been shown to decrease mortality by up to 30%. The outcome of screening failures has not been adequately studied. AIMS:The purpose of this study was to assess the outcome of patients who were diagnosed with CRC ...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-013-2702-1

    authors： Half EE,Mlynarsky L,Naftali T,Benjaminov F,Konikoff FM

    更新日期：2013-09-01 00:00:00

  • Anemia Severity Associated with Increased Healthcare Utilization and Costs in Inflammatory Bowel Disease.

    abstract：BACKGROUND:Anemia is a common systemic complication of inflammatory bowel disease (IBD) and is associated with worse disease outcomes, quality of life, and higher healthcare costs. AIMS:The purpose of this study was to determine how anemia severity impacts healthcare resource utilization and if treatment of anemia was...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-020-06590-y

    authors： Blaney H,Vu P,Mathew A,Snelling R,England J,Duong C,Hammonds K,Johnson C

    更新日期：2020-09-05 00:00:00

  • Biologic Use Patterns and Predictors for Non-persistence and Switching of Biologics in Patients with Inflammatory Bowel Disease: A Nationwide Population-Based Study.

    abstract：BACKGROUND:Data on real-life patterns of biologic use for inflammatory bowel disease (IBD) are scarce. AIMS:We aimed to examine the patterns of biologic use and the factors associated with non-persistence and switching of biologics in Korean IBD patients. METHODS:Using National Health Insurance claims, we collected d...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-019-05867-1

    authors： Jung YS,Han M,Park S,Cheon JH

    更新日期：2020-05-01 00:00:00

  • Paraoxonase (PON)1 192R allele carriage is associated with reduced risk of inflammatory bowel disease.

    abstract：:The paraoxonase (PON) genes family maps to chromosome 7q21-q22, within a loci that also showed evidence of susceptibility genes for both Crohn's disease (CD) and ulcerative colitis (UC). In this case-control study we investigated the possible relationship between PON1 and PON2 polymorphisms and the risk of inflammator...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-006-9700-5

    authors： Karban A,Hartman C,Eliakim R,Waterman M,Nesher S,Barnett-Griness O,Shamir R

    更新日期：2007-10-01 00:00:00

  • Gastroesophageal reflux disease: relationship between clinical and histological features. GOSPE. Gruppo Operativo per lo Studio delle Precancerosi dell'Esofago.

    abstract：:Our purpose was to evaluate the relationship between the clinical and histological features in a cohort of patients who had gastroesophageal reflux-related lesions diagnosed after upper digestive endoscopy. In all, 589 patients scheduled for elective endoscopy in a multicentric prospective study were evaluated. Multip...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章,多中心研究

    doi：10.1023/a:1026666417658

    authors： Aste H,Bonelli L,Ferraris R,Conio M,Lapertosa G

    更新日期：1999-12-01 00:00:00

  • A Phenome-Wide Analysis of Healthcare Costs Associated with Inflammatory Bowel Diseases.

    abstract：INTRODUCTION:Crohn's disease (CD) and ulcerative colitis (UC) are associated with considerable direct healthcare costs. There have been few comprehensive analyses of all IBD- and non-IBD comorbidities that determine direct costs in this population. METHODS:We used data from a validated cohort of patients with inflamma...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-020-06329-9

    authors： Cai W,Cagan A,He Z,Ananthakrishnan AN

    更新日期：2020-05-20 00:00:00

  • [*C]octanoic acid breath test to measure gastric emptying rate of solids.

    abstract：:We have developed a breath test to measure solid gastric emptying using a standardized scrambled egg test meal (250 kcal) labeled with [14C]octanoic acid or [13C]octanoic acid. In vitro incubation studies showed that octanoic acid is a reliable marker of the solid phase. The breath test was validated in 36 subjects by...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF02300385

    authors： Maes BD,Ghoos YF,Rutgeerts PJ,Hiele MI,Geypens B,Vantrappen G

    更新日期：1994-12-01 00:00:00

  • Nerve-mediated nitric oxide production by opossum lower esophageal sphincter.

    abstract：:Antagonists of nitric oxide synthesis inhibit nerve-induced hyperpolarization and relaxation of muscle from the opossum lower esophageal sphincter. These studies test the hypothesis that nitric oxide is released during stimulation of intrinsic esophageal nerves. The intrinsic nerves were stimulated with an electrical ...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/BF02088117

    authors： Murray J,Bates JN,Conklin JL

    更新日期：1994-09-01 00:00:00

  • Optimal administration of tacrolimus in reduced-size liver.

    abstract：:The optimal administration of immunosuppressants such as tacrolimus (Tac) for small-for-size (SFS) grafts, where the functional liver mass is small and must regenerate, has not been reported so far. The aim of this study is to clarify the characteristics of Tac metabolism according to liver volume. Seven-week-old male...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章

    doi：10.1007/s10620-008-0551-0

    authors： Morine Y,Shimada M,Torii M,Imura S,Ikegami T,Kanemura H,Arakawa Y,Hanaoka J,Kanamoto M,Nii A,Yamazaki N

    更新日期：2009-08-01 00:00:00

  • Adalimumab Maintenance Treatment in Ulcerative Colitis: Outcomes by Prior Anti-TNF Use and Efficacy of Dose Escalation.

    abstract：BACKGROUND:The impact of prior anti-TNF use on "real-life" outcomes of adalimumab therapy in ulcerative colitis (UC) is not well known. AIM:To compare the influence of prior anti-TNF use on the outcomes of adalimumab maintenance treatment in UC patients. We also assessed the effectiveness of adalimumab dose escalation...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章,多中心研究

    doi：10.1007/s10620-016-4398-5

    authors： Taxonera C,Iglesias E,Muñoz F,Calvo M,Barreiro-de Acosta M,Busquets D,Calvet X,Rodríguez A,Pajares R,Gisbert JP,López-Serrano P,Pérez-Calle JL,Ponferrada Á,De la Coba C,Bermejo F,Chaparro M,Olivares D,Alba C,Fernández

    更新日期：2017-02-01 00:00:00

  • A Systematic Review of Esophageal MicroRNA Markers for Diagnosis and Monitoring of Barrett's Esophagus.

    abstract：BACKGROUND:Esophageal epithelial microRNAs may be used to diagnose Barrett's esophagus (BE) and possibly monitor its progression to esophageal adenocarcinoma (EAC). AIMS:We reviewed studies that have investigated this to identify microRNAs with high biomarker potential for screening and disease monitoring in BE. METH...

    journal_title：Digestive diseases and sciences

    pub_type： 杂志文章,评审

    doi：10.1007/s10620-015-3959-3

    authors： Mallick R,Patnaik SK,Wani S,Bansal A

    更新日期：2016-04-01 00:00:00