Serial sectioning of a portion of a rectal biopsy detects more focal abnormalities: a prospective study of patients with inflammatory bowel disease.

abstract：:Our objective was to determine whether there are dominating racial differences in patient preferences for surgery that may explain the disparities in proctocolectomy utilization between African Americans (AA) and whites. We used the time trade-off technique to measure health preferences for undergoing ileal pouch anal...

journal_title：Digestive diseases and sciences

authors： Nguyen GC,Tuskey A,Bayless TM,LaVeist TA,Brant SR

更新日期：2008-03-01 00:00:00

abstract：:Rectally administered suspensions of 5-aminosalicylic acid (5-ASA) are topically effective in treating left-sided ulcerative colitis. The extent to which the contents of these enemas are distributed to inflamed mucosal linings has not previously been determined. This study was undertaken to validate a technique for la...

journal_title：Digestive diseases and sciences

authors： Vitti RA,Meyers F,Knight LC,Siegel JA,Malmud LS,Fisher RS

更新日期：1989-11-01 00:00:00

abstract：BACKGROUND AND AIMS:The impact of obesity on survival following liver transplantation is unclear, and existing studies report conflicting results. Our current study aims to further delineate the impact of obesity using population-based registry data from the USA. METHODS:All US adult liver transplant recipients from 2...

journal_title：Digestive diseases and sciences

authors： Wong RJ,Cheung R,Perumpail RB,Holt EW,Ahmed A

更新日期：2015-04-01 00:00:00

abstract：:We examined the effect of interleukin-1beta (IL-1beta) on spontaneous and enhanced restoration (cell migration and proliferation) using an in vitro wound model comprising a confluent monolayer of rat gastric epithelial RGM1 cells. Repair of an artificial wound in a cell monolayer was found to be time- and concentratio...

journal_title：Digestive diseases and sciences

authors： Nakamura E,Takahashi S,Matsui H,Okabe S

更新日期：1998-03-01 00:00:00

abstract：:Phlebosclerosis of the mesenteric vein is a rare condition causing chronic intestinal ischemia, it has only been reported in Japan. A 56-year-old man with liver cirrhosis and hepatic tumor presented with phlebosclerosis of mesenteric vein without any abdominal symptoms. He was admitted for examination of suspected hep...

journal_title：Digestive diseases and sciences

authors： Oshitani N,Matsumura Y,Kono M,Tamori A,Higuchi K,Matsumoto T,Seki S,Arakawa T

更新日期：2002-12-01 00:00:00

abstract：:The effect of secretin and somatostatin on secretion of epidermal growth factor (EGF) from Brunner's glands was investigated in rats. Secretin increased volume secretion and the median output of EGF rose from 720 fmol/5 hr (total range 460-1320) in controls to 2065 fmol/5 hr (total range 1560-2730) at a dose of 50 pmo...

journal_title：Digestive diseases and sciences

authors： Olsen PS,Kirkegaard P,Poulsen SS,Nexø E

更新日期：1994-10-01 00:00:00

abstract：INTRODUCTION:Combined heart-liver transplantation (CHLT) has resulted in acceptable survival rates compared to orthotopic liver transplantation (OLT) alone and orthotopic heart transplantation alone. Using the US transplant registry, we compared outcomes following sequential and combined HLT. METHODS:We conducted a re...

journal_title：Digestive diseases and sciences

authors： Yamaguchi Y,Burrier C,Roth C,Tumin D,Beal EW,Washburn K,Hayes D Jr,Tobias JD

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Eradication therapies for Helicobacter pylori infection are advancing as new acid inhibitory reagents approved. The aim of this study was to assess the efficacy and safety of vonoprazan-based triple treatment. MATERIALS AND METHODS:Triple therapy with vonoprazan and two antibiotics (amoxicillin and clarithr...

journal_title：Digestive diseases and sciences

authors： Tanabe H,Ando K,Sato K,Ito T,Goto M,Sato T,Fujinaga A,Kawamoto T,Utsumi T,Yanagawa N,Ichiishi E,Otake T,Kohgo Y,Nomura Y,Ueno N,Sugano H,Kashima S,Moriichi K,Fujiya M,Okumura T

更新日期：2017-11-01 00:00:00

abstract：:Recent evidence suggests a role of reactive oxygen intermediates (ROI) in intracellular signaling and regulation of gene expression. We examined whether expression of interleukin-8 (IL-8), a key cytokine in the inflammatory responses of gastric epithelial cells, is sensitive to antioxidants and oxidative stress. IL-8 ...

journal_title：Digestive diseases and sciences

authors： Shimada T,Watanabe N,Hiraishi H,Terano A

更新日期：1999-02-01 00:00:00

abstract：:Nine patients with concurrent myelodysplastic syndrome (MDS) and inflammatory bowel disease (IBD) were examined. Median age at diagnosis of these patients was similar to the usual age of patients at diagnosis of IBD only. There was a strong predominance of Crohn's disease (seven of nine cases), with an unusually high ...

journal_title：Digestive diseases and sciences

authors： Wang Z,Zhou Y,Liu Y

更新日期：2008-07-01 00:00:00

abstract：:This study investigated the effects of portal hypertension on gastric motor and secretory functions and the role of endothelin in rats. Control; sham-operated; endothelin-A receptor blocker, BQ 485 (1 microgram/kg)-treated; portal hypertensive; and portal hypertension +, endothelin-A receptor blocker-treated rats were...

journal_title：Digestive diseases and sciences

authors： Günal O,Yeğen C,Aktan AO,Yalin R,Yeğen BC

更新日期：1996-03-01 00:00:00

abstract：:Ninety-one patients with idiopathic constipation had segmental colonic transit studied with radiopaque markers using a new simplified technique to determine frequency and type of colonic transit time (CTT) abnormalities and to determine the utility of this test in planning therapy. Colonic transit studies defined four...

journal_title：Digestive diseases and sciences

authors： Chaussade S,Khyari A,Roche H,Garret M,Gaudric M,Couturier D,Guerre J

更新日期：1989-08-01 00:00:00

abstract：OBJECTIVES:Pancreas divisum (PD) as a cause of pancreatitis has been debated. In this study, we report the association of multiple gene polymorphisms on the risk of RAP in the presence of PD. DESIGN:We enrolled 687 individuals (167 IRAP, 276 ICP, and 244 unrelated healthy controls) from May 2015 to September 2016. Pat...

journal_title：Digestive diseases and sciences

authors： Talukdar R,Aslam M,Reddy DN,Nabi Z,Shava U,Ravikanth VV,Avanthi S,Govardhan B

更新日期：2020-08-04 00:00:00

abstract：BACKGROUND:Colonoscopy is associated with multiple adverse outcomes. With an aging population undergoing colorectal cancer screening, few modalities exist to assess the patient risk prior to colonoscopy. Frailty, the age-related decline in reserve and function across multiple organ systems, predicts poor surgical outco...

journal_title：Digestive diseases and sciences

authors： Taleban S,Toosizadeh N,Junna S,Golden T,Ghazala S,Wadeea R,Tirambulo C,Mohler J

更新日期：2018-12-01 00:00:00

abstract：:Diamine oxidase (DAO) is an enzyme whose low plasma values are enhanced by an intravenous injection of heparin, which releases the enzyme from the enterocytes of the villous tips. In 20 normal controls and 15 untreated subjects affected with an overt malabsorption syndrome and subtotal atrophy shown by Crosby jejunal ...

journal_title：Digestive diseases and sciences

authors： D'Agostino L,Ciacci C,Daniele B,Barone MV,Sollazzo R,Mazzacca G

更新日期：1987-03-01 00:00:00

abstract：:The authors have developed a primate model for evaluating cytoprotection against alcohol-induced injury in gastric mucosa pretreated with antiulcer agents. In the present study, groups of squirrel monkeys received either a single oral dose of misoprostol (500 or 200 micrograms/kg), cimetidine (3 or 6 mg/kg), placebo, ...

journal_title：Digestive diseases and sciences

authors： Liss RH,Letourneau RJ,Schepis JP

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Nonalcoholic fatty liver disease (NAFLD) is now recognized as a leading cause of liver dysfunction. Gastroesophageal reflux disease (GERD) is a common disorder causing symptoms that often impair patients' quality of life. In recent years, the prevalence of both these diseases has increased, partially overlap...

journal_title：Digestive diseases and sciences

authors： Catanzaro R,Calabrese F,Occhipinti S,Anzalone MG,Italia A,Milazzo M,Marotta F

更新日期：2014-08-01 00:00:00

abstract：:Continuous noninvasive measurement of local blood flow at one or more chosen sites will be useful during experiments on the liver, during liver surgery, or after hepatic transplantation. We have compared a Clark-type flow-dependent oxygen electrode having a 3-mm-diameter cathode applied to the surface of rabbit liver ...

journal_title：Digestive diseases and sciences

authors： Piasecki C,Seifalian AM

更新日期：1990-03-01 00:00:00

abstract：:Although the association between acute pancreatitis and pleuropulmonary damage is well documented, so far no information on lung function in patients with chronic pancreatitis is available. In this study functional, radiological, and clinical investigations have been carried out in 42 patients affected by chronic calc...

journal_title：Digestive diseases and sciences

authors： Masoero G,Spinaci S,Arossa W,Andriulli A,Gaia E,De Pretis G,Dobrilla G,De la Pierre M

更新日期：1984-10-01 00:00:00

abstract：:Fractional systemic bioavailability of orally administered drugs was found to be unexpectedly low in liver cirrhosis, even after surgical portal-systemic shunting. Fecal loss or intestinal first-pass elimination were assumed to explain the finding. In this paper we evaluated alternative pathophysiological interpretati...

journal_title：Digestive diseases and sciences

authors： Molino G,Avagnina P,Garrone C,Sansoè G,Degerfeld MM,Peretti P,Tinivella M,Bianco S

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Proton pump inhibitors (PPIs) may reduce the risk of esophageal adenocarcinoma (EAC) in patients with Barrett's esophagus. PPIs are prescribed for virtually all patients with Barrett's esophagus, irrespective of the presence of reflux symptoms, and represent a de facto chemopreventive agent in this populatio...

journal_title：Digestive diseases and sciences

authors： Sharaiha RZ,Freedberg DE,Abrams JA,Wang YC

更新日期：2014-06-01 00:00:00

abstract：:Papillary stenosis is an imprecisely defined clinical syndrome which eludes definitive diagnosis. In this study we evaluated 26 patients with suspected papillary stenosis by manometric examination of the sphincter of Oddi done during ERCP examination. Basal pressure in the sphincter of Oddi was elevated in 14 of the p...

journal_title：Digestive diseases and sciences

authors： Bar-Meir S,Geenen JE,Hogan WJ,Dodds WJ,Stewart ET,Arndorfer RC

更新日期：1979-03-01 00:00:00

abstract：:Of 112 patients with peptic ulcer disease examined for oral carriage of Candida, 66 (59%) were carriers. Candida carriage was associated with blood group O (P < 0.05) and, independently, with nonsecretion of blood group antigens (P < 0.01). For each subject, the presence or absence of yeasts was found to be a constant...

journal_title：Digestive diseases and sciences

authors： Burford-Mason AP,Willoughby JM,Weber JC

更新日期：1993-08-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is widely considered to be the hepatic manifestation of the metabolic syndrome and is closely linked to dyslipidemia, obesity, and insulin resistance. Patients with NAFLD have increased mortality when compared to the general population, primarily related to cardiovascular disea...

journal_title：Digestive diseases and sciences

authors： Simon TG,Corey KE,Chung RT,Giugliano R

更新日期：2016-12-01 00:00:00

abstract：:It has been suggested that elevated serum lipoprotein cholesterol levels may be a determinant of biliary cholesterol saturation and cholesterol gallstone disease. The aim of this study was to correlate serum lipoprotein cholesterol and apolipoprotein levels with biliary cholesterol saturation in patients with gallston...

journal_title：Digestive diseases and sciences

authors： Marks JW,Cleary PA,Albers JJ

更新日期：1984-12-01 00:00:00

abstract：BACKGROUND:Gut inflammation is prevalent in chronic kidney disease (CKD) and likely contributes to systemic inflammation via disruption of the epithelial tight junction with subsequent endotoxin and bacterial translocation. AIMS:To study the expression profile of inflammatory and tight junction proteins in the colon f...

journal_title：Digestive diseases and sciences

authors： Lau WL,Liu SM,Pahlevan S,Yuan J,Khazaeli M,Ni Z,Chan JY,Vaziri ND

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), which are most abundant in the liver, are the main enzymes involved in ethanol and acetaldehyde metabolism. AIMS:The purpose of this study was to compare the activity of ADH isoenzymes and ALDH between liver carcinoma cells and healthy hepatocyt...

journal_title：Digestive diseases and sciences

authors： Jelski W,Zalewski B,Szmitkowski M

更新日期：2008-09-01 00:00:00

abstract：:The impact of depression (assessed by the Beck Depression Inventory) on quality of life and outcome was prospectively assessed in adult patients with cirrhosis. Patients with depression had significantly poorer perceived quality of life (P = 0.006), poorer adaptive coping (P = 0.001), and lower functional status, i.e....

journal_title：Digestive diseases and sciences

authors： Singh N,Gayowski T,Wagener MM,Marino IR

更新日期：1997-07-01 00:00:00

abstract：:Concordance between gram-negative enteric and other toxin-producing bacteria in blood and stool culture, endotoxin (lipopolysaccharide), and interleukin-6 (IL-6) was measured in 60 preterm infants (600-1600 g) as a clinical index in neonatal necrotizing enterocolitis (NEC). E. coli, Klebsiella, Enterobacter, and Clost...

journal_title：Digestive diseases and sciences

authors： Duffy LC,Zielezny MA,Carrion V,Griffiths E,Dryja D,Hilty M,Rook C,Morin F 3rd

更新日期：1997-02-01 00:00:00

abstract：:Apoptosis is an important process in a wide variety of different biological systems. In addition to caspases, recently, calpains, another family of proteases, have been found to be involved in apoptosis of many cell systems. This study is designed with the aims to evaluate the possible effect of Z-LLY-FMK (a calpain i...

journal_title：Digestive diseases and sciences

authors： Sheen-Chen SM,Ho HT,Eng HL

更新日期：2009-11-01 00:00:00