Interleukin-1beta inhibits growth factor-stimulated restoration of wounded rat gastric epithelial cell monolayers.

abstract：:The changes in plasma and duodenal cholecystokinin (CCK) concentrations after pancreatic duct occlusion were examined in rats. The rats were sacrificed 1, 3, 7, 10, 14, and 30 days after occlusion of the duct. Histological examination showed acute inflammation on days 1 and 3 after duct occlusion, interstitial fibrosi...

journal_title：Digestive diseases and sciences

authors： Miyasaka K,Funakoshi A,Jimi A,Nakamura R,Matsumoto M,Kitani K

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:Liver stiffness measurement (LSM) by transient elastography is a popular noninvasive test of fibrosis. Traditional LSM cutoffs dichotomize patients and do not clearly indicate the confidence of diagnosis. AIM:We derived and validated probability functions of fibrosis and cirrhosis based on LSM and determine...

journal_title：Digestive diseases and sciences

authors： Wong VW,Lampertico P,de Lédinghen V,Chang PE,Kim SU,Chen Y,Chan HL,Mangia G,Foucher J,Chow WC,Ahn SH,Hou J

更新日期：2015-05-01 00:00:00

abstract：:The double pylorus is a fistulous communication between the gastric antrum and duodenal bulb. In most instances, it is believed to be a complication of peptic ulcer disease. In prior reports, the longest follow-up has been only 5 years. We report four cases of double pylorus, three of which have been followed medicall...

journal_title：Digestive diseases and sciences

authors： Einhorn RI,Grace ND,Banks PA

更新日期：1984-03-01 00:00:00

abstract：:Autoimmune hepatitis (AIH) is rare in Asian countries compared to the West, and an exceptionally low prevalence was noted previously in Taiwan. Using the revised criteria of the IAIHG, 48 cases of AIH patients were diagnosed. All patients were consecutively diagnosed over a period of 5 years. Detailed medical historie...

journal_title：Digestive diseases and sciences

authors： Koay LB,Lin CY,Tsai SL,Lee C,Lin CN,Sheu MJ,Kuo HT,Sun CS

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH), which are most abundant in the liver, are the main enzymes involved in ethanol and acetaldehyde metabolism. AIMS:The purpose of this study was to compare the activity of ADH isoenzymes and ALDH between liver carcinoma cells and healthy hepatocyt...

journal_title：Digestive diseases and sciences

authors： Jelski W,Zalewski B,Szmitkowski M

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Previous studies have shown vitamin D status to be associated with disease activity in patients with inflammatory bowel disease (IBD), but its influence on the clinical course of IBD has not been established. AIMS:We aimed to analyze whether the serum 25-hydroxyvitamin D3 [25(OH)D] status is associated with...

journal_title：Digestive diseases and sciences

authors： Ham NS,Hwang SW,Oh EH,Kim J,Lee HS,Park SH,Yang DH,Ye BD,Byeon JS,Myung SJ,Yang SK

更新日期：2020-03-26 00:00:00

abstract：BACKGROUND AND AIMS:Matrix metalloproteinase-2 (MMP-2), a type IV collagenase secreted by activated hepatic stellate cells (HSCs), is upregulated in chronic liver disease and is considered a profibrotic mediator due to its proliferative effect on cultured HSCs and ability to degrade normal liver matrix. Although associ...

journal_title：Digestive diseases and sciences

authors： Radbill BD,Gupta R,Ramirez MC,DiFeo A,Martignetti JA,Alvarez CE,Friedman SL,Narla G,Vrabie R,Bowles R,Saiman Y,Bansal MB

更新日期：2011-02-01 00:00:00

abstract：:Sulfated and unsulfated bile acid composition was studied in serum and bile in 10 patients with alcoholic cirrhosis. Samples, collected before and 2 months after portacaval anastomosis, were analyzed using a gaschromatographic method. Mean total serum bile acid levels rose from 32.0 +/- 5.3 (SE) mumol/liter before to ...

journal_title：Digestive diseases and sciences

authors： Capocaccia L,Attili AF,Cantafora A,Bracci F,Paciscopi L,Puoti C,Pièche U,Angelico M

更新日期：1981-06-01 00:00:00

abstract：:Glucagon-like peptide-2 (GLP-2) is an enteroendocrine hormone which is uniquely trophic for the intestine; a physiological role in regulating nutrient absorptive capacity is becoming apparent. GLP-2, independent of enteral feeding, stimulates a classical pattern of intestinal adaptation in terminal ileum following res...

journal_title：Digestive diseases and sciences

authors： Sigalet DL,Bawazir O,Martin GR,Wallace LE,Zaharko G,Miller A,Zubaidi A

更新日期：2006-09-01 00:00:00

abstract：:Endoscopic injection sclerotherapy is known to cause a variety of motility abnormalities, but the correlation between these changes and symptomatology has not been clearly defined. To assess the effects of endoscopic sclerosis of varices on esophageal function and symptoms, we prospectively studied esophageal motility...

journal_title：Digestive diseases and sciences

authors： Cohen LB,Simon C,Korsten MA,Scherl EJ,Skorniky J,Guelrud MB,Waye JD

更新日期：1985-01-01 00:00:00

abstract：:Choledochoduodenostomy may be followed by the "sump syndrome." This previously required surgical intervention. We describe the successful application of endoscopic therapy in two patients with this syndrome. ...

journal_title：Digestive diseases and sciences

authors： Barkin JS,Silvis S,Greenwald R

更新日期：1980-08-01 00:00:00

abstract：BACKGROUND:The incidence of Clostridium difficile infection is increasing in the United States. The aim of our investigation is to compare short-term and long-term outcomes of patients admitted with an ulcerative colitis (UC) flare and co-existent C. difficile infection to those of non-infected patients. METHODS:A his...

journal_title：Digestive diseases and sciences

authors： Jodorkovsky D,Young Y,Abreu MT

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:Diagnosis of pediatric inflammatory bowel diseases (IBD) remains challenging. We aimed at the value of immunohistochemical assessment of CD30+ lymphocytes in the intestinal mucosa in differential diagnosis between pediatric Crohn's disease (CD) and ulcerative colitis (UC) and its utility as a predictor of fu...

journal_title：Digestive diseases and sciences

authors： Fabian O,Hradsky O,Drskova T,Mikus F,Zamecnik J,Bronsky J

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND AND AIM:Dietary fiber shortens gut transit time, but data on the effects of fiber components (including resistant starch, RS) on intestinal contractility are limited. We have examined RS effects in male Sprague-Dawley rats fed either a high-amylose maize starch (HAMS) or a wholemeal made from high-amylose wh...

journal_title：Digestive diseases and sciences

authors： Patten GS,Kerr CA,Dunne RA,Shaw JM,Bird AR,Regina A,Morell MK,Lockett TJ,Molloy PL,Abeywardena MY,Topping DL,Conlon MA

更新日期：2015-06-01 00:00:00

abstract：:Duodenogastric reflux (DGR) was assessed with 24-hour gastric bilirubin monitoring in 345 patients (219 men; 49 +/- 13 years) with foregut symptoms and 41 healthy subjects (24 men, 28 +/- 5 years). Bilirubin exposure was measured as percent time above absorbance level 0.25 and excessive DGR was defined above the 95th ...

journal_title：Digestive diseases and sciences

authors： Fein M,Freys SM,Sailer M,Maroske J,Tigges H,Fuchs KH

更新日期：2002-12-01 00:00:00

abstract：:Peutz-Jeghers syndrome (PJS) is an autosomal-dominant inherited disorder characterized by mucocutaneous pigmentation, hamartomatous polyposis of the gastrointestinal tract, and an increased risk for the development of both gastrointestinal and extraintestinal malignancies. Germline mutation of the STK11 gene, which en...

journal_title：Digestive diseases and sciences

authors： Gao Y,Zhang FM,Huang S,Wang X,Zhang P,Huang XD,Ji GZ,Fan ZN

更新日期：2010-04-01 00:00:00

abstract：:We compared the growth rate of locally recurrent hepatocellular carcinoma (HCC) with that of primary HCC. After the first treatment by transcatheter arterial chemoembolization (TACE), 60 locally recurrent HCC nodules were reviewed. The tumor volume doubling time (DT) of locally recurrent HCC was significantly shorter ...

journal_title：Digestive diseases and sciences

authors： Tezuka M,Hayashi K,Kubota K,Sekine S,Okada Y,Ina H,Irie T

更新日期：2007-03-01 00:00:00

abstract：:The present study reports the results of intravenous cyclosporine in 32 patients with refractory and/or severe attacks of ulcerative colitis (UC). Twenty of 32 patients responded to intravenous cyclosporine; cyclosporine was clinically effective and improved colonic lesions. However, one colonic perforation and one po...

journal_title：Digestive diseases and sciences

authors： Carbonnel F,Boruchowicz A,Duclos B,Soulé JC,Lerebours E,Lémann M,Belaïche J,Colombel JF,Cosnes J,Gendre JP

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Activation of the transcription factor NF-κB and expression of pro-inflammatory mediators have been considered as major events of acute pancreatitis (AP). Karyopherin alpha 2 (KPNA2), a member of the importin α family, reportedly modulates p65 subcellular localization. AIM:This study aimed to investigate th...

journal_title：Digestive diseases and sciences

authors： Cai Y,Shen Y,Gao L,Chen M,Xiao M,Huang Z,Zhang D

更新日期：2016-03-01 00:00:00

abstract：:Barrett's esophagus (BE) is a well-known premalignant condition that can be associated with the development of dysplasia and adenocarcinoma. In the past, esophagectomy was the standard treatment for patients with BE with high grade dysplasia (HGD) and early cancer (EC). However, esophagectomy is not necessarily the on...

journal_title：Digestive diseases and sciences

authors： Azarm A,Lukolic I,Shukla M,Concha-Parra R,Gress F

更新日期：2012-12-01 00:00:00

abstract：:Several epidemiological studies have demonstrated a close association between Helicobacter pylori infection and carcinoma of the mid- or distal stomach. If this can be shown to be a causal association, eradication of the organism may prevent later development of cancer. Several mechanisms have been proposed by which H...

journal_title：Digestive diseases and sciences

authors： Hahm KB,Lee KJ,Kim JH,Cho SW,Chung MH

更新日期：1998-09-01 00:00:00

abstract：:Concentration and voltage dependence of unidirectional Mg fluxes across the rat colon ascendens were measured in a modified Ussing chamber. Mucosa (M) to serosa (S) Mg flux exhibits a cellular component, whereas SM flux is totally diffusive. At all the concentrations between 0.125 and 8 mmol/liter MS Mg transport is h...

journal_title：Digestive diseases and sciences

authors： Karbach U

更新日期：1989-12-01 00:00:00

abstract：:Cyclic GMP plays an important role in maintaining homeostasis in the gastric mucosa. NSAIDs damage the mucosa by mechanisms that may be mediated by alterations in the intragastric concentration of cyclic GMP. To test this hypothesis we studied the effects of the oral administration of acetylsalicylic acid (100, 300, a...

journal_title：Digestive diseases and sciences

authors： Herrerías JM,Esteban JM,Caballero-Plasencia AM,Valenzuela-Barranco M,Motilva V,Alarcón C,Martín J,Herrerías JM Jr,Esteban P

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Whether addition of prokinetics to proton pump inhibitors improves esophageal peristalsis and symptoms in patients with gastroesophageal reflux disease (GERD) remains unknown. AIM:We evaluated the effect of mosapride, a 5-HT4 agonist, and PPI cotherapy in patients with GERD on esophageal motility using high...

journal_title：Digestive diseases and sciences

authors： Cho YK,Choi MG,Park EY,Lim CH,Kim JS,Park JM,Lee IS,Kim SW,Choi KY

更新日期：2013-04-01 00:00:00

abstract：:Intravenous lidocaine was infused at 0.82 ml/min in a concentration of 1.2 mg/ml (2.3 mg/kg) for 120 min in awake chair-restrained baboons (Papio anubis), and measurements of esophageal peristalsis and LES pressure were compared before and after lidocaine or control infusions. Lidocaine produced a progressive and sign...

journal_title：Digestive diseases and sciences

authors： Sinar DR,Carey LC,Cordova C,Fletcher JR,Castell DO

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND:Primary liver cancer constitutes an increasingly malignancy in the Western world and one of the leading causes of cancer-related deaths worldwide. The purpose of this study was to evaluate and compare long-term outcomes after R0 resections in noncirrhotic livers for hepatocellular carcinoma (HCC) and intrahe...

journal_title：Digestive diseases and sciences

authors： Sotiropoulos GC,Bockhorn M,Sgourakis G,Brokalaki EI,Molmenti EP,Neuhäuser M,Radtke A,Wohlschlaeger J,Baba HA,Broelsch CE,Lang H

更新日期：2009-04-01 00:00:00

abstract：:The synthetic prostanoid, Ro 22-6923, was studied for its effects on canine gastric secretion. Histamine-stimulated acid secretion was inhibited for up to 8 hr after an orally administered dose of 0.25 mg/kg Ro 22-6923. In the Amdrup (modified Pavlov) pouch model, Ro 22-6923 significantly inhibited food-stimulated aci...

journal_title：Digestive diseases and sciences

authors： Gaginella TS,Bertko RJ,Müller RK,Gallo-Torres H,Sullivan AC

更新日期：1985-04-01 00:00:00

abstract：:The effect of the race of the donor on organ donation and on the outcome of clinical liver transplantation has not been addressed previously. The aims of this study were to determine: (1) the number of organs donated by each of the major racial groups of the United States, (2) the outcome of transplantation of these o...

journal_title：Digestive diseases and sciences

authors： Pillay P,Van Thiel DH,Gavaler JS,Starzl TE

更新日期：1990-11-01 00:00:00

abstract：:Autoregulation of blood flow in the denervated, autoperfused dog stomach was studied before and during local intraarterial infusion of histamine. Histamine caused an increase in gastric blood flow and oxygen uptake. The increased oxygen uptake was due entirely to an increased blood flow, ie, oxygen extraction was not ...

journal_title：Digestive diseases and sciences

authors： Perry MA,Murphree D,Granger DN

更新日期：1982-08-01 00:00:00

abstract：:Despite progress in therapeutic approaches for the elimination of hepatitis C, chronic hepatitis C virus infection remains an important cause of liver disease. Therapeutic intervention with the currently available interferon-based treatment regimens is quite successful, but treatment is difficult to tolerate and is co...

journal_title：Digestive diseases and sciences

authors： Davis GL,Krawczynski K,Szabo G

更新日期：2007-04-01 00:00:00