R0 liver resections for primary malignant liver tumors in the noncirrhotic liver: a diagnosis-related analysis.

abstract：:In order to investigate whether the human exocrine pancreas is capable of adapting to a diet with a high-carbohydrate, low-fat, and normal protein content, 10 healthy subjects were given a continuous intraduodenal infusion of such a dietary composition (8760 kJ in 2400 ml/day) via a portable infusion pump over a perio...

journal_title：Digestive diseases and sciences

authors： Emde C,Liehr RM,Gregor M,Pleul O,Riecken EO,Menge H

更新日期：1985-03-01 00:00:00

abstract：:We measured suprahepatic vein and arterial partial oxygen pressure in 35 alcoholics with severe (N = 7) or mild (N = 28) histological liver damage and without evidence of clinical liver failure. The suprahepatic vein was punctured with a fine needle, using a percutaneous approach. Suprahepatic vein partial oxygen pres...

journal_title：Digestive diseases and sciences

authors： Bunout D,Moya P,de la Maza MP,Petermann M,Iturriaga H,Hirsch S

更新日期：1995-06-01 00:00:00

abstract：:Modern methods of diagnosing diarrhea-predominant irritable bowel syndrome (D-IBS) require a "diagnosis of exclusion" approach. In this study we aim to test the diagnostic ability of using the fluctuation of frequency and consistency of bowel patterns in IBS to discriminate it from other causes of diarrhea. Eligible s...

journal_title：Digestive diseases and sciences

authors： Pimentel M,Hwang L,Melmed GY,Low K,Vasiliauskas E,Ippoliti A,Yang J,Lezcano S,Conklin JL,Sahakian A

更新日期：2010-01-01 00:00:00

abstract：:Signet ring carcinoma of the pancreas is rare. We report a case which was remarkable for (1) diffuse, infiltrating growth which suggested chronic pancreatitis at laparotomy, and (2) an associated very high circulating carcinoembryonic antigen (CEA) level of 6400 ng/ml. The case report and autopsy are presented. Twelve...

journal_title：Digestive diseases and sciences

authors： Tracey KJ,O'Brien MJ,Williams LF,Klibaner M,George PK,Saravis CA,Zamcheck N

更新日期：1984-06-01 00:00:00

abstract：PURPOSE:Guidelines recommend routine invasive screening for Helicobacter pylori in patients with peptic ulcer hemorrhage (PUH). However, compliance with screening remains suboptimal. The aim of this study was to determine if a simplified approach based on noninvasive screening is cost effective in PUH. RESULTS:In the ...

journal_title：Digestive diseases and sciences

authors： Atreja A,Fu AZ,Sanaka MR,Vargo JJ

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:The chemokine SDF-1 and its receptor CXCR4 are essential for the proper functioning of multiple organs. In the liver, cholangiocytes and hepatic progenitor cells (HPCs) are the main cells that produce SDF-1, and SDF-1 is thought to be essential for HPC-stimulated liver regeneration. AIMS:In this study, CXCR...

journal_title：Digestive diseases and sciences

authors： Tsuchiya A,Imai M,Kamimura H,Takamura M,Yamagiwa S,Sugiyama T,Nomoto M,Heike T,Nagasawa T,Nakahata T,Aoyagi Y

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:This study aimed to objectively investigate whether the addition of polydextrose to sterilized probiotic containing Lactobacillus helveticus will confer benefits to constipation-predominant irritable bowel syndrome patients. METHODS:A total of 163 patients were randomized into two groups: Group A to consume...

journal_title：Digestive diseases and sciences

authors： Bahrudin MF,Abdul Rani R,Tamil AM,Mokhtar NM,Raja Ali RA

更新日期：2020-02-01 00:00:00

abstract：:Motion sickness provides a unique setting for the study of nausea. Studies of illusory self-motion have linked nausea and objective measures of gastric dysrhythmias and the stress hormones vasopressin and epinephrine. Electrogastrographic methods utilize Ag-AgCl electrodes placed on the abdominal surface in the epigas...

journal_title：Digestive diseases and sciences

authors： Koch KL

更新日期：1999-08-01 00:00:00

abstract：:A large retrospective autopsy study of patients was analyzed to evaluate the major etiologic and pathologic factors contributing to fatal acute pancreatitis (AP). From an autopsy population of 50,227 patients, 405 cases were identified where AP was defined as the official primary cause of death. AP was classified acco...

journal_title：Digestive diseases and sciences

authors： Renner IG,Savage WT 3rd,Pantoja JL,Renner VJ

更新日期：1985-10-01 00:00:00

abstract：:The effect on the mucosa of sodium nitrite that enters the colon from the ileum or transmucosally from the circulation is unknown. Isolated colonic mucosal cells and Roux-en-Y colostomies were used to test whether high doses of sodium nitrite (5-40 mM) had any harmful histological or inhibitory metabolic actions on th...

journal_title：Digestive diseases and sciences

authors： Roediger WE,Radcliffe BC,Deakin EJ,Nance SH

更新日期：1986-05-01 00:00:00

abstract：BACKGROUNDS AND AIMS:We studied the intestinotrophic hormone glucagon-like peptide-2 (GLP-2) as a possible therapy for non-steroidal anti-inflammatory drug (NSAID)-induced intestinal ulcers. Luminal nutrients release endogenous GLP-2 from enteroendocrine L cells. Since GLP-2 is degraded by dipeptidyl peptidase IV (DPPI...

journal_title：Digestive diseases and sciences

authors： Inoue T,Higashiyama M,Kaji I,Rudenkyy S,Higuchi K,Guth PH,Engel E,Kaunitz JD,Akiba Y

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Eosinophilic gastroenteritis (EOGE) is a rare idiopathic disease characterized by eosinophil-predominant inflammation of the stomach and/or intestines. Our aims are to determine the epidemiology, clinical features and outcomes of EOGE cases in a tertiary-care hospital. METHODS:Retrospective cohort study of ...

journal_title：Digestive diseases and sciences

authors： Alhmoud T,Hanson JA,Parasher G

更新日期：2016-09-01 00:00:00

abstract：:A 68-year-old man developed hepatic injury with no hypersensitivity reaction after three years of hydralazine therapy. The liver injury histologically showed centrilobular zonal necrosis. Clinical, biochemical, and histological recovery followed discontinuation of the drug. Challenge tests and serial liver biopsies re...

journal_title：Digestive diseases and sciences

authors： Itoh S,Yamaba Y,Ichinoe A,Tsukada Y

更新日期：1980-11-01 00:00:00

abstract：:We describe a case with prolonged survival of 2 years in a female patient with pancreatic ductal adenocarcinoma who, at diagnosis, already had liver spread and eventually succumbed to brain metastases which scanned positive with [(111)In-DTPA] octreotide scintiscan (OctreoScan). Subsequently, the patient underwent a c...

journal_title：Digestive diseases and sciences

authors： Marepaily R,Micheals D,Sloan A,Hatfield J,Adsay V,Joyrich R,Ullah N,Tobi M

更新日期：2009-01-01 00:00:00

abstract：:Our aim was to determine the effect of intestinal transection and resection on the prevalence of enteric flora and evaluate whether any such changes alter luminal SCFA and lactic acid content. Dogs underwent either 50% proximal (PR, N = 6) or distal (DR, N = 7) resection, distal resection with bypass of the ileocecal ...

journal_title：Digestive diseases and sciences

authors： Thompson JS,Quigley EM,Adrian TE

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Numerous experiments have shown that alcohol dehydrogenase (ADH) and aldehyde dehydrogenase (ALDH) are present in cells of various cancer and can play role in carcinogenesis. In previous investigations we have found elevated levels of alcohol dehydrogenase class III activity in pancreatic cancer cells. It ca...

journal_title：Digestive diseases and sciences

authors： Jelski W,Zalewski B,Szmitkowski M

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Eosinophilic esophagitis (EoE) is defined by a minimum of 15 eosinophils (eos) per high-powered field (HPF) on esophageal biopsy, along with esophageal symptoms and the exclusion of gastroesophageal reflux (GERD). The clinical significance of fewer eosinophils is unknown. METHODS:Fifty-nine adult patients w...

journal_title：Digestive diseases and sciences

authors： Ravi K,Talley NJ,Smyrk TC,Katzka DA,Kryzer L,Romero Y,Arora AS,Alexander JA

更新日期：2011-07-01 00:00:00

abstract：:The pathogenesis of nonalcoholic steatohepatitis (NASH) remains poorly understood. Since inflammation and fatty changes are associated with hepatitis C (HCV) infection, we have tested the role of HCV in the genesis of NASH. Five consecutive cases of classic NASH were tested by Abbott anti-c100-3 EIA and polymerase cha...

journal_title：Digestive diseases and sciences

authors： Rogers DW,Lee CH,Pound DC,Kumar S,Cummings OW,Lumeng L

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Acute variceal bleeding (AVB) in patients with cirrhosis is associated with high mortality, ranging from 12 to 20% at 6 weeks. The existing prognostic models for AVB lack precision and require further validation. AIM:In this prospective study, we aimed to develop and validate a new prognostic model for AVB,...

journal_title：Digestive diseases and sciences

authors： Rout G,Sharma S,Gunjan D,Kedia S,Saraya A,Nayak B,Singh V,Kumar R,Shalimar

更新日期：2019-08-01 00:00:00

abstract：:Up to 60% of patients with IBS have lowered perception thresholds in the rectum to balloon distension. The current study sought to test the hypothesis that IBS patients with normal perception thresholds in the rectum show hypersensitivity of afferent pathways in the sigmoid colon. Eleven healthy normal subjects and ei...

journal_title：Digestive diseases and sciences

authors： Lembo T,Munakata J,Naliboff B,Fullerton S,Mayer EA

更新日期：1997-06-01 00:00:00

abstract：:A detailed comparison was made of the bile acid composition in gallstones (brown pigment stones) and paired bile and liver from both affected and unaffected lobes by gallstones, which were taken at operation from 16 patients with hepatolithiasis, with the aim of elucidating whether stone formation is derived from poss...

journal_title：Digestive diseases and sciences

authors： Shoda J,Tanaka N,He BF,Matsuzaki Y,Osuga T,Miyazaki H

更新日期：1993-11-01 00:00:00

abstract：:Acid inhibition increases gastric mucosal susceptibility to damage by luminal acid. This might be due to reduced metabolic CO2 and bicarbonate whereas, during normal acid, secretion cytoprotective CO2/HCO3- production parallels acid production. Metabolic activity and mucosal damage caused by luminal acid perfusion was...

journal_title：Digestive diseases and sciences

authors： Glauser M,Bauerfeind P,Feil W,Riegler M,Fraser R,Blum AL

更新日期：1996-05-01 00:00:00

abstract：:The possible role of Saccharomyces boulardii, a nonpathogenic yeast with beneficial effects on the human intestine, in the maintenance treatment of Crohn's disease has been evaluated. Thirty-two patients with Crohn's disease in clinical remission (CDAI < 150) were randomly treated for six months with either mesalamine...

journal_title：Digestive diseases and sciences

authors： Guslandi M,Mezzi G,Sorghi M,Testoni PA

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:Lymphocytic esophagitis is a rare esophageal condition. Our knowledge of potential risk factors and treatment outcomes of lymphocytic esophagitis is limited. AIM:To investigate potential risk factors associated with the development of lymphocytic esophagitis and compare clinical characteristics and treatmen...

journal_title：Digestive diseases and sciences

authors： Zaver HB,Ghoz H,Malviya BJ,Brahmbhatt B,Palmer WC,Lacy BE,DeVault KR,Krishna M,Bi Y

更新日期：2020-11-20 00:00:00

abstract：:This study set out to evaluate the effects of dietary fiber on cancer development in the large bowel under in vivo experimental conditions as similar as possible to those under which this cancer develops in vivo in humans. Forty-eight Sprague-Dawley rats were divided into three groups that were fed either a nonfiber d...

journal_title：Digestive diseases and sciences

authors： Iwane S,Nakaji S,Ohta M,Tamura K,Sakamoto J,Munakata A,Sugawara K

更新日期：2002-06-01 00:00:00

abstract：:Background/Aims Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) as a newly identified biological agent has shown promising antitumor effects in a wide range of cancers. However, gastric cancer cells are less sensitive than other cancer cells to TRAIL-induced apoptosis.Here, we combined TRAIL with borte...

journal_title：Digestive diseases and sciences

authors： Liu J,Qu XJ,Xu L,Zang Y,Qu JL,Hou KZ,Liu YP

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND AIMS:Prior to the consensus guideline conference in 2007, eosinophilic esophagitis (EoE) was uncommon dominated by the fibrostenotic phenotype, but over the past decade has become a common cause of dysphagia with more inflammatory phenotypes diagnosed. We assessed the impact of guideline definitions on t...

journal_title：Digestive diseases and sciences

authors： Lipka S,Boyce HW,Kumar A,Richter JE

更新日期：2015-06-01 00:00:00

abstract：:Development of type 1 insulin-dependent diabetes mellitus has been recently reported in patients who underwent interferon-alpha (IFN-alpha) therapy because of chronic viral hepatitis. Furthermore IFN-alpha seems to be involved in the immunological events that lead to beta-cell destruction and development of type 1 dia...

journal_title：Digestive diseases and sciences

authors： di Cesare E,Previti M,Russo F,Brancatelli S,Ingemi MC,Scoglio R,Mazzù N,Cucinotta D,Raimondo G

更新日期：1996-08-01 00:00:00

abstract：:As immunosuppressive agents, corticosteroids may be considered an appropriate treatment for primary biliary cirrhosis, even if bone loss and other side effects may occur. We studied biliary lipid metabolism in 10 nonicteric patients, with histologically proven primary biliary cirrhosis (stage I-IV). We administered me...

journal_title：Digestive diseases and sciences

authors： Mazzella G,Fusaroli P,Pezzoli A,Azzaroli F,Mazzeo C,Zambonin L,Simoni P,Festi D,Roda E

更新日期：1999-12-01 00:00:00

abstract：BACKGROUND:Recent data suggest the involvement of both the adaptive and the innate immune system in celiac disease (CD). However, little is known about the immune phenotype of children with CD and its alteration upon dietary intervention. AIMS:We characterized the prevalence of major interacting members of the adaptiv...

journal_title：Digestive diseases and sciences

authors： Cseh Á,Vásárhelyi B,Szalay B,Molnár K,Nagy-Szakál D,Treszl A,Vannay Á,Arató A,Tulassay T,Veres G

更新日期：2011-03-01 00:00:00