Signet ring carcinoma of the pancreas, a rare variant with very high CEA values. Immunohistologic comparison with adenocarcinoma.

Abstract:

:Signet ring carcinoma of the pancreas is rare. We report a case which was remarkable for (1) diffuse, infiltrating growth which suggested chronic pancreatitis at laparotomy, and (2) an associated very high circulating carcinoembryonic antigen (CEA) level of 6400 ng/ml. The case report and autopsy are presented. Twelve other cases of pancreatic adenocarcinoma (non-signet ring) are compared with the signet ring carcinoma with respect to CEA staining and circulating levels. We conclude immunocytochemical staining of biopsy tissue for CEA is a useful adjunct in the interpretation of circulating CEA levels in pancreatic carcinoma.

journal_name

Dig Dis Sci

authors

Tracey KJ,O'Brien MJ,Williams LF,Klibaner M,George PK,Saravis CA,Zamcheck N

doi

10.1007/BF01296277

subject

Has Abstract

pub_date

1984-06-01 00:00:00

pages

573-6

issue

6

eissn

0163-2116

issn

1573-2568

journal_volume

29

pub_type

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