Dipeptidyl peptidase IV inhibition prevents the formation and promotes the healing of indomethacin-induced intestinal ulcers in rats.

abstract：:Infection with Helicobacter pylori is associated with the development of gastric cancer. To study whether the infection with H. pylori strains expressing the vacuolating cytotoxin (VacA) and/or the cytotoxin-associated protein (CagA) is associated with an increased risk of developing gastric adenocarcinoma, sera of 90...

journal_title：Digestive diseases and sciences

authors： Rudi J,Kolb C,Maiwald M,Zuna I,von Herbay A,Galle PR,Stremmel W

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:Polymerase chain reaction (PCR) assays are the standard for detecting hepatitis C virus viremia. The transcription-mediated amplification (TMA)-based assay is more sensitive. METHODS:We retrospectively reviewed the charts of patients with a post-end of treatment (EOT) PCR-/TMA+ result to assess the clinical...

journal_title：Digestive diseases and sciences

authors： Thadani A,Harley J,Rubin J,Lebovics E

更新日期：2012-01-01 00:00:00

abstract：:Lansoprazole, a proton pump inhibitor, exerts prominent antiulcer activity via both antisecretory and mucosal protective actions. Although the antisecretory action has been explained by inactivation of (H+, K+)-ATPase in parietal cells, the mode of mucosal protective action remains to be elucidated. In the present stu...

journal_title：Digestive diseases and sciences

authors： Inada I,Satoh H

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Whether addition of prokinetics to proton pump inhibitors improves esophageal peristalsis and symptoms in patients with gastroesophageal reflux disease (GERD) remains unknown. AIM:We evaluated the effect of mosapride, a 5-HT4 agonist, and PPI cotherapy in patients with GERD on esophageal motility using high...

journal_title：Digestive diseases and sciences

authors： Cho YK,Choi MG,Park EY,Lim CH,Kim JS,Park JM,Lee IS,Kim SW,Choi KY

更新日期：2013-04-01 00:00:00

abstract：PURPOSE:Studies investigating the association between aspirin use and gastric cancer risk have reported conflicting results. The objective of this study was to quantitatively summarize the evidence for such a relationship. RESULTS:Two investigators independently searched the Medline, PubMed, Embase, and Academic Searc...

journal_title：Digestive diseases and sciences

authors： Yang P,Zhou Y,Chen B,Wan HW,Jia GQ,Bai HL,Wu XT

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND/AIM:We have previously reported that bee venom (BV) has a protective role against acute pancreatitis (AP). However, the effects of apamin, the major compound of BV, on AP have not been determined. The aim of this study was to evaluate the effects of apamin on cerulein-induced AP. METHODS:AP was induced via ...

journal_title：Digestive diseases and sciences

authors： Bae GS,Heo KH,Park KC,Choi SB,Jo IJ,Seo SH,Kim DG,Shin JY,Kang DG,Lee HS,Song HJ,Shin BC,Park SJ

更新日期：2013-10-01 00:00:00

abstract：:There is A paucity of data on racial differences in epidemiology of irritable bowel syndrome (IBS) alone and un-investigated dyspepsia (UD) alone compared to "overlap syndrome" (OS). We conducted a random survey (n = 990). Subjects completed a questionnaire which included Rome II criteria for IBS and functional dyspep...

journal_title：Digestive diseases and sciences

authors： Minocha A,Chad W,Do W,Johnson WD

更新日期：2006-01-01 00:00:00

abstract：:Pheripheral edema was observed in five female patients after taking proton pump inhibitors omeprazole, lansoprazole, or pantoprazole for 7-15 days for peptic acid diseases in recommended standard doses. Edema disappeared two to three days after stopping therapy but reappeared in all five patients after being reexposed...

journal_title：Digestive diseases and sciences

authors： Brunner G,Athmann C,Boldt JH

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Hepatitis C (HCV) knowledge is limited in injection drug users (IDU). Vulnerable populations including IDUs are disproportionally affected by HCV. Effective HCV education can potentially reduce disparity in HCV prevalence and its outcome in this population. AIM:This study aimed to assess the impact of forma...

journal_title：Digestive diseases and sciences

authors： Surjadi M,Torruellas C,Ayala C,Yee HF Jr,Khalili M

更新日期：2011-01-01 00:00:00

abstract：:The hydrogen (H2) lactose breath test (BT) is a test commonly used for the diagnosis of hypolactasia. However, its sensitivity is not always good. In the last few years, the new Quick Lactase Test (QLT) has been developed for endoscopic diagnosis of adult-type hypolactasia. The aim of this study was to compare the eff...

journal_title：Digestive diseases and sciences

authors： Ojetti V,La Mura R,Zocco MA,Cesaro P,De Masi E,La Mazza A,Cammarota G,Gasbarrini G,Gasbarrini A

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:The use of volatile organic compounds (VOCs) in bile was recently studied and appeared promising for diagnosis of malignancy. Noninvasive diagnosis of malignant biliary strictures by using VOCs in urine has not been studied. AIM:To identify potential VOCs in urine to diagnose malignant biliary strictures. ...

journal_title：Digestive diseases and sciences

authors： Navaneethan U,Parsi MA,Lourdusamy D,Grove D,Sanaka MR,Hammel JP,Vargo JJ,Dweik RA

更新日期：2015-07-01 00:00:00

abstract：:There is growing recognition of the importance of assessing patient perceptions of treatment, especially patient satisfaction. The Gastroesophageal Reflux Disease (GERD) Treatment Satisfaction Questionnaire (GTSQ) was developed to assess satisfaction with GERD medication. A web-based survey, which included the GTSQ an...

journal_title：Digestive diseases and sciences

authors： Shikiar R,Flood E,Siddique R,Howell J,Dodd SL

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Intraductal ultrasonography (IDUS) is a useful procedure for diagnosing microlithiasis in the bile duct but it is not easy to differentiate between tiny echogenicity and real microlithiasis. We compared the echogenicity seen on IDUS and the findings of bile microscopy (BM) of bile that was collected in the c...

journal_title：Digestive diseases and sciences

authors： Kim BJ,Kang P,Lee JK,Sinn DH,Lee KH,Lee KT,Rhee JC,Lim JH

更新日期：2010-03-01 00:00:00

abstract：:The peroxisome proliferator-activated receptor gamma (PPARgamma) is a nuclear receptor highly expressed in the colon and playing an anti-inflammatory role through inhibition of the NF-kappaB pathway. Toll-like receptor 4 (TLR4) has been known to mediate LPS-induced cellular signaling through activation of NF-kappaB pa...

journal_title：Digestive diseases and sciences

authors： Eun CS,Han DS,Lee SH,Paik CH,Chung YW,Lee J,Hahm JS

更新日期：2006-04-01 00:00:00

abstract：:The changes in plasma and duodenal cholecystokinin (CCK) concentrations after pancreatic duct occlusion were examined in rats. The rats were sacrificed 1, 3, 7, 10, 14, and 30 days after occlusion of the duct. Histological examination showed acute inflammation on days 1 and 3 after duct occlusion, interstitial fibrosi...

journal_title：Digestive diseases and sciences

authors： Miyasaka K,Funakoshi A,Jimi A,Nakamura R,Matsumoto M,Kitani K

更新日期：1992-03-01 00:00:00

abstract：:In a Caucasian woman with a history of ocular and pulmonary sarcoidosis, the occurrence of sclerosing peritonitis with exudative ascites but without any of the well-known causes of this syndrome prompts us to consider that sclerosing peritonitis is a manifestation of sarcoidosis. The dramatic improvement that occurred...

journal_title：Digestive diseases and sciences

authors： Ngô Y,Messing B,Marteau P,Nouël O,Pasquiou A,Lavergne A,Rambaud JC

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Approximately 10-28 % of patients experience adverse drug reactions related to treatment with thiopurines. The most serious reaction is myelosuppression, typically manifested as leucopenia, which occurs in approximately 2-5 % of patients. Other adverse drug reactions that often accompany thiopurine therapy a...

journal_title：Digestive diseases and sciences

authors： Wroblova K,Kolorz M,Batovsky M,Zboril V,Suchankova J,Bartos M,Ulicny B,Pav I,Bartosova L

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Determining the risk stratification of nonvariceal upper gastrointestinal bleeding (NVUGIB) plays a vital role in treating upper gastrointestinal bleeding (UGIB). Traditional scores like Glasgow-Blatchford score (GBS), Rockall score (RS), and AIMS65 score have been widely utilized in UGIB practice, however e...

journal_title：Digestive diseases and sciences

authors： Yue W,Liu Y,Jiang W,Huang J,Liu J

更新日期：2020-06-24 00:00:00

abstract：BACKGROUND:As several factors can contribute to low bone mineral density (BMD), we investigated the role of vitamin D in low BMD while controlling for other risk factors in inflammatory bowel diseases (IBD) patients. METHODS:We conducted a prospective cross-sectional study between 2008 and 2012 in adult IBD patients. ...

journal_title：Digestive diseases and sciences

authors： Abraham BP,Prasad P,Malaty HM

更新日期：2014-08-01 00:00:00

abstract：:Papillary stenosis is an imprecisely defined clinical syndrome which eludes definitive diagnosis. In this study we evaluated 26 patients with suspected papillary stenosis by manometric examination of the sphincter of Oddi done during ERCP examination. Basal pressure in the sphincter of Oddi was elevated in 14 of the p...

journal_title：Digestive diseases and sciences

authors： Bar-Meir S,Geenen JE,Hogan WJ,Dodds WJ,Stewart ET,Arndorfer RC

更新日期：1979-03-01 00:00:00

abstract：:It has been suggested that elevated serum lipoprotein cholesterol levels may be a determinant of biliary cholesterol saturation and cholesterol gallstone disease. The aim of this study was to correlate serum lipoprotein cholesterol and apolipoprotein levels with biliary cholesterol saturation in patients with gallston...

journal_title：Digestive diseases and sciences

authors： Marks JW,Cleary PA,Albers JJ

更新日期：1984-12-01 00:00:00

abstract：:Stimulation of the intrinsic nerves of the esophageal body leads to a twitch of the circular muscle after the end of the stimulation (the esophageal off-response), and the twitch spreads in the distal direction because of a latency gradient in the onset of the off-response between the proximal and the distal esophagus...

journal_title：Digestive diseases and sciences

authors： Ren J,Schulze-Delrieu K

更新日期：1989-04-01 00:00:00

abstract：:Some endoscopic trainees find it difficult to manipulate an endoscope's controls, possibly due to small hand size. To assess this, a survey was mailed to all gastroenterology fellows in the US. Two hundred twenty-seven of 1,295 (17.5%) fellows responded. Median surgical glove size was 7.5. Ninety-three respondents (41...

journal_title：Digestive diseases and sciences

authors： Cohen DL,Naik JR,Tamariz LJ,Madanick RD

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:New molecular biology-based methods of bacterial identification are expected to help elucidate the relationship between colorectal cancer (CRC) and intestinal microbiota. Although there is increasing evidence revealing the potential role of microbiota in CRC, it remains unclear whether microbial dysbiosis is...

journal_title：Digestive diseases and sciences

authors： Ohigashi S,Sudo K,Kobayashi D,Takahashi O,Takahashi T,Asahara T,Nomoto K,Onodera H

更新日期：2013-06-01 00:00:00

abstract：:Glutamine synthetase is responsible for the ATP-dependent amidation of glutamate to glutamine. In liver the enzyme is highly localized in perivenous hepatocytes; in brain the enzyme is localized in astrocytes. Portacaval anastomosis resulted in liver atrophy, hyperammonemia, and up to 90% loss of glutamine synthetase ...

journal_title：Digestive diseases and sciences

authors： Girard G,Butterworth RF

更新日期：1992-07-01 00:00:00

abstract：:A previous study showed that supine gastroesophageal reflux occurs mainly in the early nighttime period and is greater if the patient retires within 2 hr of a meal. We analyzed 306 consecutive esophageal pH studies between January and July 2003. Ninety-two patients had abnormal supine reflux. The recumbent period was ...

journal_title：Digestive diseases and sciences

authors： King AL,Baburajan B,Wong T,Anggiansah R,Anggiansah A

更新日期：2007-10-01 00:00:00

abstract：:Colonoscopy is the dominant colorectal cancer screening strategy in the USA. There are no randomized controlled trials completed of screening colonoscopy, but multiple lines of evidence establish that colonoscopy reduces colorectal cancer incidence in both the proximal and distal colon. Colonoscopy is highly operator ...

journal_title：Digestive diseases and sciences

authors： Rex DK

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND/AIM:Transarterial chemoembolization (TACE) is the recommended treatment for patients with Barcelona stage B hepatocellular carcinoma; however, community practice varies from these American Association for the Study of Liver Diseases guidelines. In this study, we sought to assess factors determining outcome a...

journal_title：Digestive diseases and sciences

authors： Barman PM,Sharma P,Krishnamurthy V,Willatt J,McCurdy H,Moseley RH,Su GL

更新日期：2014-11-01 00:00:00

abstract：:Heme oxygenase (HO)-1, the rate-limiting enzyme in heme degradation, is induced by oxidative stress and its major end product, bilirubin, is a potent physiological antioxidant. We studied the induction of HO-1 and bilirubin production in intestinal mucosa using a rat model of sepsis. E. coli lipopolysaccharide was adm...

journal_title：Digestive diseases and sciences

authors： Otani K,Shimizu S,Chijiiwa K,Morisaki T,Yamaguchi T,Yamaguchi K,Kuroki S,Tanaka M

更新日期：2000-12-01 00:00:00

abstract：:Trichinella spiralis infection in rodents is a well-known model of intestinal inflammation associated with hypermotility and hypersecretion. Our aim was to use this experimental model to elucidate if iNOS was involved in the development of gastrointestinal hypermotility. Rats infected with Trichinella spiralis were tr...

journal_title：Digestive diseases and sciences

authors： Torrents D,Prats N,Vergara P

更新日期：2003-06-01 00:00:00